CN102198307B - External composition - Google Patents
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- CN102198307B CN102198307B CN201110026523XA CN201110026523A CN102198307B CN 102198307 B CN102198307 B CN 102198307B CN 201110026523X A CN201110026523X A CN 201110026523XA CN 201110026523 A CN201110026523 A CN 201110026523A CN 102198307 B CN102198307 B CN 102198307B
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- rosae rugosae
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Abstract
The invention relates to a composition for Chinese traditional massage, which is prepared from the following raw medicines: rose, clove, cumin, moxa powder and the like. The preparation method of the composition comprises the following steps of: respectively crushing the dried rose, clove and cumin; then, uniformly mixing with 96 parts of moxa powder; and packing with cotton cloth to obtain the composition. The composition provided by the invention has excellent functions of activating blood circulation, dissipating blood stasis, expelling cold, relieving pain, eliminating viruses and improving the capability of the lung for resisting viruses.
Description
Technical field
The present invention relates to a kind of Chinese traditional massage with opening up, particularly have blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain effect Chinese traditional massage with opening up.
Background technology
The used in the market shape thing of opening up all is to process with cotton parcel crude salt granule, and use the heating back only has the fomentation effect, and does not see medicated powder is mixed back parcel fomentation.
Summary of the invention
One object of the present invention is to disclose the external medicine composition of a kind of blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain effect.
Another object of the present invention is that the external that discloses a kind of blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain effect opens up.
The present invention seeks to realize through following technical scheme:
The external medicine composition of a kind of blood circulation promoting and blood stasis dispelling of the present invention, dispersing cold for relieving pain is processed (weight ratio) by following crude drug:
Flos Rosae Rugosae 1-10 weight portion, Flos Caryophylli 1-10 weight portion, Fructus Foeniculi 0.1-5 weight portion, Chinese mugwort powder 70-120 weight portion.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 2-6 weight portion, Flos Caryophylli 2-6 weight portion, Fructus Foeniculi 0.2-2 weight portion, Chinese mugwort powder 75-100 weight portion.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 2.5 weight portions, Flos Caryophylli 2 weight portions, Fructus Foeniculi 0.5 weight portion, Chinese mugwort powder 96 weight portions.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 4.5 weight portions, Flos Caryophylli 1.5 weight portions, Fructus Foeniculi 1 weight portion, Chinese mugwort powder 70 weight portions.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 5.5 weight portions, Flos Caryophylli 5.5 weight portions, Fructus Foeniculi 4 weight portions, Chinese mugwort powder 70 weight portions.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 5.5 weight portions, Flos Caryophylli 5.5 weight portions, Fructus Foeniculi 4 weight portions, Chinese mugwort powder 70 weight portions.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 2.5 weight portions, Flos Caryophylli 1.5 weight portions, Fructus Foeniculi 4 weight portions, Chinese mugwort powder 100 weight portions.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, process by following crude drug:
Flos Rosae Rugosae 1.5 weight portions, Flos Caryophylli 7.5 weight portions, Fructus Foeniculi 0.9 weight portion, Chinese mugwort powder 110 weight portions.
Fructus Foeniculi is the dry mature fruit of samphire Fructus Foeniculi Foeniculum vulgare Mill., preferred salt Fructus Foeniculi in the above-mentioned Chinese medicine composition.Flos Caryophylli is the dry flower of plant clove of myrtaceae Eugenia caryophllata Thunb..Flos Rosae Rugosae is the dry flower of rosaceous plant Flos Rosae Rugosae Rosa rugosa Thunb..
The Chinese mugwort powder is that Folium Artemisiae Argyi (for the dried leaves of feverfew Chinese mugwort Artemisia argyi Levl.et Vant.) is bought by conventional method preparation or market.Said Chinese mugwort powder can be the carbonization powder that ends.
The present invention also provides the method for preparing of the external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain; This method is: process various externally applied products with Chinese mugwort powder uniform mixing behind Flos Rosae Rugosae, Flos Caryophylli, the Fructus Foeniculi pulverize separately, comprise and process Chinese mugwort goods (moxa roll, Ai Zhu), outer deposited bag.
The external medicine composition of above-mentioned blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain is prepared into the method that external opens up: dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Flos Rosae Rugosae character is gentle, suitable for men women and children in the above-mentioned prescription, can chill out, balance endocrine, the gas of enriching blood, and U.S. face skin protection has the effect of conditioning to liver and stomach, but and allaying tiredness, improves body constitution.The Flos Caryophylli property and flavor of peppery and warm, warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Fructus Foeniculi is warm in nature, and acrid in the mouth, hardship are invigorated blood circulation, promoting the circulation of QI, pain relieving, can be used for breast side of body epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling etc.Chinese mugwort powder toil, temperature is gone into spleen, liver, kidney channel, has the blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive effect.Hot compress after the mentioned component Hybrid Heating has blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain effect, has the effect that improves immunity simultaneously.
Experimental example 1 effect experiment
The experiment of 1 blood circulation promoting and blood stasis dispelling
1.1 material
1.1.1 receive the reagent thing: A is opened up in external: Flos Rosae Rugosae 0.125g, Flos Caryophylli 0.1g, Fructus Foeniculi 0.025g, Chinese mugwort powder 4.8g; B is opened up in external: Chinese mugwort powder 4.8g; C is opened up in external: Chinese mugwort powder 4.8g, Flos Rosae Rugosae 0.125g, Flos Caryophylli 0.125g; D is opened up in external: Chinese mugwort powder 4.8g, Flos Caryophylli 0.2g, Fructus Foeniculi 0.05g.This cotton is opened up with applying behind the pan even heating and is pressed in the animal abdominal part.
1.1.2 control drug: activating meridians to stop pain cream is membranous patch, is the sharp drugmaker of Henan antelope product.
1.1.3 reagent: adrenalin hydrochloride injection; Heparin; Chloral hydrate all has Beijing to encircle inferior Imtech to be provided.
1.1.4 animal subject: the Wistar male rat, 260-300g, the quality certification number are: SCXK (capital) 2006-0009 is provided by Beijing Vital River Experimental Animals Technology Co., Ltd..Each Mus is tested preceding 24 hours abdominal part QUMAO, is convenient to medication.Conventional feed is fed, and freely drinks water, and the laboratory environment temperature is 22 ± 2 ℃.
1.1.5 instrument: the LG-R-80A type washes the blood viscosity appearance automatically, and Beijing Steellex Scientific Instrument Company provides; The 400R refrigerated centrifuge, German Heraeus product.
1.2 method
1.2.1 divide into groups and administration: 70 rats are divided into 7 groups at random by body weight: matched group, the blood stasis model group, A, B, C, D group are opened up in activating meridians to stop pain cream group and external.The all drug of topical application in 3 days in advance of each group, all with gauze and immobilization with adhesive tape, the medicine contact area is 1.2cm*1.2cm, every day 2 times, each 1 hour.Matched group and model group cotton parcel crude salt grain are processed.
1.2.2 blood stasis model is set up: modeling after each administration group cleaning topical remedy behind the medicine was applied in experiment the same day.Subcutaneous injection epinephrine 1mgkg, totally 2 times, interval 4h, (4 ℃) 5min in the mixture of ice and water is immersed with rat in the centre.
1.2.3 collection of specimens: after drug of topical application next day 1 hour, (the RCCA intubate was got blood, heparin (20000UL for 10% chloral hydrate, 0.35ml/100g) anesthesia with chloral hydrate with rat
-1) anticoagulant.Each index of mensuration hemorheology under 25 ℃ of constant temperature.
1.2.4 hemorheology index is measured
1.2.4.1 the mensuration of whole blood viscosity is got anticoagulant blood sample 1mL, is placed on the LG-R-80A type and washes automatically in the blood viscosity appearance sample cell, surveys 37 ℃ respectively and descends it at high shear rate (200s
-1), middle shear rate (30s
-1), low shear rate (5s
-1) under whole blood viscosity.
1.2.4.2 the blood plasma viscosity measurement is got the 3mL anticoagulation, with 3000rmin
-1Centrifugal 10min gets blood plasma 0.8mL, places in the blood viscosity appearance sample cell, surveys its 100s
-1Blood plasma viscosity under the shear rate.
1.2.4.3 after hematocrit capillary tube was got whole blood, plasticine shutoff one end was put the centrifugal 5min of centrifuge 10000rmin, reads packed cell volume with the packed cell volume reading plate.1.2.4.4 reduced viscosity calculates with the ratio calculating whole blood reduced viscosity of whole blood viscosity with packed cell volume.
1.3 result
Each group statistical data is organized a t check; The result shows; Rat is after the heavy dose of epinephrine load of subcutaneous injection frozen water soaks; Whole blood viscosity, whole blood reduced viscosity, blood plasma viscosity, packed cell volume all obviously increase under each shear rate of model group rat, and hemorheology is glutinous, dense blood stasis state, and each index compares with matched group that all there were significant differences.Positive control activating meridians to stop pain cream group and external open up that A group, external are opened up the C group, external is opened up the D group and all can obviously be reduced whole blood viscosity under each shear rate, and the external effect of opening up the A group is better than external and opens up the C group and open up the D group with external, and the B group is opened up in external does not then have obvious acting on; Positive control activating meridians to stop pain cream group significantly reduces whole blood reduced viscosity under the high and low shear rate, and the A group is opened up in external can significantly reduce whole blood reduced viscosity under the low shear rate, and external is opened up B group, external and opened up C group and external and open up the D group and does not then have obviously and act on; Positive control activating meridians to stop pain cream group and external open up that A group, external are opened up the C group, external is opened up the D group and all can obviously be reduced packed cell volume and blood plasma viscosity; And the effect that A group is opened up in external is better than, and the B group is opened up in external, the C group is opened up in external and D group (*: P < 0.05 is opened up in external; *: P 0.01), see table 1-4.
The mPas that influences to blood stasis rat whole blood viscosity is opened up in table 1 external
The mPas that influences to blood stasis rat reduction whole blood viscosity is opened up in table 2 external
The influence to blood stasis rat packed cell volume is opened up in table 3 external
The influence to blood stasis rat plasma viscosity is opened up in table 4 external
2 analgesic experiments
2.1 the influence to the mouse writhing reaction is opened up in external
2.1.1 material
2.1.1.1 receive the reagent thing: A is opened up in external: Flos Rosae Rugosae 8.3mg, Flos Caryophylli 6.6mg, Fructus Foeniculi 1.7mg, Chinese mugwort powder 318.7mg; B is opened up in external: Chinese mugwort powder 318.7mg; C is opened up in external: Chinese mugwort powder 318.7m g, Flos Rosae Rugosae 10.0mg, Flos Caryophylli 6.6mg; D is opened up in external: Chinese mugwort powder 318.7m g, Flos Caryophylli 13.2mg, Fructus Foeniculi 3.4mg.This cotton is opened up with applying behind the pan even heating and is pressed in the animal abdominal part.
2.1.1.2 control drug: activating meridians to stop pain cream is membranous patch, is the sharp drugmaker of Henan antelope product.
2.1.1.3 reagent: glacial acetic acid has Beijing to encircle inferior Imtech to be provided.
2.1.1.4 animal subject: SPF level ICR mice, ♂, 18-22g, the quality certification number are: SCXK (capital) 2006-0009 is provided by Beijing Vital River Experimental Animals Technology Co., Ltd..Each Mus is tested preceding 24 hours with depilatory abdominal part QUMAO, is convenient to medication.Conventional feed is fed, and freely drinks water, and the laboratory environment temperature is 20 ± 2 ℃.
2.1.2 method
2.1.2.1 divide into groups and administration: 84 male mices are divided into 7 groups at random by body weight: matched group, model group, A, B, C, D group are opened up in activating meridians to stop pain cream group and external.The all drug of topical application in 3 days in advance of each group, all with gauze and immobilization with adhesive tape, the medicine contact area is 0.7cm*0.7cm, every day 2 times, each 1 hour.Matched group and model group cotton parcel crude salt grain are processed.
2.1.2.2 acetic acid twisting reaction model: clean every Mus lumbar injection 0.6% glacial acetic acid 0.1ml10g after the topical remedy
-1
2.1.2.3 index determining: what record injection caused each Mus in back 15 minutes of the pain turns round the body number of times, and the comparable group differences carries out statistical analysis.
2.1.3 result
Behind the lumbar injection glacial acetic acid, each model group mice pain is obvious, shows as writhing response.What positive control activating meridians to stop pain cream group and external opened up that A group and external open up that the C group can obviously suppress mice turns round the body number of times, and the external effect of opening up the A group is better than external and opens up C and organize; External open up B group and external open up D organize can suppress mice turn round the body number of times, but with model group relatively do not have significant difference (* P 0.05, * * P 0.01).The result sees table 5.
The influence to glacial acetic acid induced mice writhing response is opened up in table 5 external
2.2 the influence that the mice hot plate is caused the pain reaction is opened up in external
2.2.1 material
2.2.1.1 receive the reagent thing: A is opened up in external: Flos Rosae Rugosae 8.3mg, Flos Caryophylli 6.6mg, Fructus Foeniculi 1.7mg, Chinese mugwort powder 318.7mg; B is opened up in external: Chinese mugwort powder 318.7mg; C is opened up in external: Chinese mugwort powder 318.7m g, Flos Rosae Rugosae 10.0mg, Flos Caryophylli 6.6mg; D is opened up in external: Chinese mugwort powder 318.7mg, Flos Caryophylli 13.2mg, Fructus Foeniculi 3.4mg.This cotton is opened up with applying behind the pan even heating and is pressed in the animal abdominal part.
2.2.1.2 control drug: activating meridians to stop pain cream is membranous patch, is the sharp drugmaker of Henan antelope product.
2.2.1.3 animal subject: SPF level ICR mice, ♀, 18-22g, the quality certification number are: SCXK (capital) 2006-0009 is provided by Beijing Vital River Experimental Animals Technology Co., Ltd..Each Mus is tested preceding 24 hours abdominal part QUMAO, is convenient to medication.Conventional feed is fed, and freely drinks water, and the laboratory environment temperature is 20 ± 2 ℃.
2.2.1.4 instrument: hot plate, water-bath, Shanghai Jie Weifu mechanical & electronic equipment corporation, Ltd.
2.1.2 method
2.1.2.1 divide into groups and administration: 72 female mices are divided into 6 groups at random by body weight: matched group, positive control activating meridians to stop pain cream group and external are opened up A, B, C, D group.The all drug of topical application in 3 days in advance of each group, all with gauze and immobilization with adhesive tape, the medicine contact area is 0.7cm*0.7cm, every day 2 times, each 1 hour.Matched group cotton parcel crude salt grain is processed.
2.1.2.2 mice hot plate reaction model is set up: after cleaning topical remedy, respectively mice is placed on 56 ± 0.5 ℃ of hot plates.
2.1.2.3 index determining: time (second) of licking metapedes pain threshold as this Mus after the administration occurs licking with stopwatch record mice, pain threshold surpasses 60 seconds persons by calculating in 60 seconds.
2.1.3 result
After being placed on mice on 56 ± 0.5 ℃ of hot plates, each model group mice pain is obvious, shows as to lick and licks metapedes.The A group is opened up in activating meridians to stop pain cream group and external can obviously improve the pain threshold of mice; External is opened up B group, external and is opened up C group and external and open up the D group and can improve the pain threshold of mice, but with model group relatively do not have significant difference (* P 0.05, * * P 0.01).The result sees table 6.
The influence to the reaction of mice hot plate is opened up in table 6 external
Brief summary
The external that contains Chinese mugwort powder, Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi is opened up the blood stasis model that adrenalin hydrochloride load ice-water bath is caused and is had the improvement effect, obviously suppresses whole blood viscosity, whole blood reduced viscosity, packed cell volume and blood plasma viscosity; And single with the Chinese mugwort powder, the powder that perhaps ends, Flos Rosae Rugosae and Flos Caryophylli combination, though Chinese mugwort powder, Flos Caryophylli and Fructus Foeniculi combination can improve above index, effect is all opened up not as good as the external that four flavor Chinese medicines share.
The specific embodiment
Embodiment 1:
Flos Rosae Rugosae 2.5g, Flos Caryophylli 2g, Fructus Foeniculi 0.5g, Chinese mugwort powder 96g
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Embodiment 2:
Flos Rosae Rugosae 4.5g, Flos Caryophylli 1.5g, Fructus Foeniculi 1g, Chinese mugwort powder 70g
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Embodiment 3:
Flos Rosae Rugosae 5.5g, Flos Caryophylli 5.5g, Fructus Foeniculi 4g, Chinese mugwort powder 70g
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Embodiment 4:
Flos Rosae Rugosae 5.5g, Flos Caryophylli 5.5g, Fructus Foeniculi 4g, Chinese mugwort powder 70g
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Embodiment 5:
Flos Rosae Rugosae 2.5g, Flos Caryophylli 1.5g, Fructus Foeniculi 4g, Chinese mugwort powder 100g.
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Embodiment 6:
Flos Rosae Rugosae 1.5g, Flos Caryophylli 7.5g, Fructus Foeniculi 0.9g, Chinese mugwort powder 110g.
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into the type of opening up with cotton.Take out this cotton during use and open up, rub repeatedly and rub with deposited pressing behind the pan even heating in body surface.
Claims (7)
1. an external is opened up, and it is characterized in that it being that crude drug by following weight ratio is processed:
Flos Rosae Rugosae 1-10 weight portion, Flos Caryophylli 1-10 weight portion, Fructus Foeniculi 0.1-5 weight portion, Chinese mugwort powder 70-120 weight portion.
2. as claimed in claim 1 opening up is characterized in that it being that crude drug by following weight ratio is processed:
Flos Rosae Rugosae 2.5 weight portions, Flos Caryophylli 2 weight portions, Fructus Foeniculi 0.5 weight portion, Chinese mugwort powder 96 weight portions.
3. external medicine composition is characterized in that it being that crude drug by following weight ratio is processed:
Flos Rosae Rugosae 1-10 weight portion, Flos Caryophylli 1-10 weight portion, Fructus Foeniculi 0.1-5 weight portion, Chinese mugwort powder 70-120 weight portion.
4. Chinese medicine composition as claimed in claim 3 is characterized in that it being that crude drug by following weight ratio is processed: Flos Rosae Rugosae 2-6 weight portion, Flos Caryophylli 2-6 weight portion, Fructus Foeniculi 0.2-2 weight portion, Chinese mugwort powder 75-100 weight portion.
5. Chinese medicine composition as claimed in claim 3 is characterized in that it being that crude drug by following weight ratio is processed:
Flos Rosae Rugosae 2.5 weight portions, Flos Caryophylli 2 weight portions, Fructus Foeniculi 0.5 weight portion, Chinese mugwort powder 96 weight portions.
6. like the method for preparing of the arbitrary described Chinese medicine composition of claim 3-5, it is characterized in that this method is: process various externally applied products with Chinese mugwort powder uniform mixing behind Flos Rosae Rugosae, Flos Caryophylli, the Fructus Foeniculi pulverize separately.
7. according to claim 1 or claim 2 the method for preparing of opening up is characterized in that this method comprises the steps:
Dry Flos Rosae Rugosae, Flos Caryophylli, Fructus Foeniculi are pulverized the back separately with Chinese mugwort powder uniform mixing, be rolled into cotton and open up.
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| CN201110026523XA CN102198307B (en) | 2010-03-22 | 2011-01-25 | External composition |
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|---|---|---|---|
| CN201010128936.4 | 2010-03-22 | ||
| CN201010128936 | 2010-03-22 | ||
| CN201110026523XA CN102198307B (en) | 2010-03-22 | 2011-01-25 | External composition |
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| CN102198307B true CN102198307B (en) | 2012-10-10 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1149418A (en) * | 1995-11-09 | 1997-05-14 | 王玉玺 | Seasoning powder |
| CN2307591Y (en) * | 1997-02-05 | 1999-02-17 | 陈财先 | Multi-effect health-care pillow with Chinese traditional herb, western medicine flower-and-plant and mineral substance |
| CN1218828A (en) * | 1997-11-28 | 1999-06-09 | 田军民 | Natural fruit wine and its producing method |
| CN1254520A (en) * | 1999-11-01 | 2000-05-31 | 济南联合大学 | Compound oil-resin flavouring |
| CN101378734A (en) * | 2006-02-10 | 2009-03-04 | 佰欧杰尼瑞克斯制药有限公司 | Microtablet-based pharmaceutical preparation |
-
2011
- 2011-01-25 CN CN201110026523XA patent/CN102198307B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1149418A (en) * | 1995-11-09 | 1997-05-14 | 王玉玺 | Seasoning powder |
| CN2307591Y (en) * | 1997-02-05 | 1999-02-17 | 陈财先 | Multi-effect health-care pillow with Chinese traditional herb, western medicine flower-and-plant and mineral substance |
| CN1218828A (en) * | 1997-11-28 | 1999-06-09 | 田军民 | Natural fruit wine and its producing method |
| CN1254520A (en) * | 1999-11-01 | 2000-05-31 | 济南联合大学 | Compound oil-resin flavouring |
| CN101378734A (en) * | 2006-02-10 | 2009-03-04 | 佰欧杰尼瑞克斯制药有限公司 | Microtablet-based pharmaceutical preparation |
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