CN102178756B - Oral liquid for treating high altitude disease (HAD) and preparation method thereof - Google Patents
Oral liquid for treating high altitude disease (HAD) and preparation method thereof Download PDFInfo
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Abstract
The invention discloses oral liquid which is mainly prepared from Tibetan medicine-food dual-purpose herbal materials, and in particular relates to oral liquid for treating high altitude disease (HAD), which overcomes defects that most of the medicines for treating AHAD need to be taken a few days in advance and have no effect on acute high altitude disease (AHAD) in the prior art. The oral liquid is mainly prepared from brassica rapa linn. juice, hippophae thibetana juice, rheum emodi wall juice, rhodiola crenulata extracting solution and potentilla anserine extracting solution; and the medicine-food dual-purpose herbal materials fully exert efficacy of adjusting physiological functions of a human body by means of reasonable matching of a plurality of components so that the oral liquid has the function of rapidly and efficiently treating HAD. The invention further provides a method for preparing the oral liquid for treating AHAD. The oral liquid can be used for rapidly and effectively relieving adverse symptoms of AHAD and improving sign index without any adverse reaction or toxic or side effect; and the oral liquid is easy to produce and the preparation method is very simple.
Description
Technical field
The present invention relates to a kind of oral liquid, particularly relate to a kind of to the west of Tibetan medicine food dual purpose plant raw material be the oral liquid of main component, belong to functional oral liquid and manufacture field thereof.
Background technology
Altitude sickness is that acute high altitude sickness is after the people arrives certain height above sea level, and draught head, the oxygen content cause because of height above sea level are few in order to adapt to for health, the variation of air drying etc., and the natural physiological reaction that produces.When the people arrives the about 2700m of the height above sea level left and right sides, just have altitude sickness.Altitude sickness has become the key factor of the west lags fars such as the Qinghai-Tibet development tourism of serious restriction China, commerce and trade, production.Even threaten national defense construction and the national security in China western part.
The altitude sickness prevention medicine of selling in the market mainly contains plateau recovering capsule, Rhodiola rosea capsules, Radix Panacis Quinquefolii ball etc., and these altitude sickness prevention medicines all will be asked for help and a few days ago be begun to take entering the highlands prerequisite.From pill taker's reaction, there are two point defects in the medicine of this class altitude sickness prevention: the one, and took in advance in the past these medicines and can cause human body to be on wires entering the plateau, cause suitable inadaptable and side effect to the people; The 2nd, take such medicine to acute high altitude reaction almost without any effect, the unique method of disposing at present acute high altitude reaction is intravenous drip, but in most of the cases do not possess corresponding medical condition, to cause the plateau pneumochysis mortality rate very high because of altitude sickness.
Summary of the invention
Purpose of the present invention is exactly for the deficiencies in the prior art, provide a kind of can rapid recovery and to altitude sickness prevention, the oral liquid of acute high altitude reaction particularly.
For achieving the above object, technical scheme of the present invention is as follows:
A kind of oral liquid for resisting altitude stress, take Tibet plant juice, plant extraction liquid as main component, it is characterized in that: described Tibet plant juice comprises Tibet Radix Brassicae Rapae natural juice, Fructus Hippophae thibetanae natural juice, Radix Rhei emodi natural juice, and described plant extraction liquid comprises Radix Rhodiolae extracting solution, Radix potentillae anserinae extracting solution.
Above-mentioned oral liquid is take the natural juice of traditional effect Tibet medicine food dual purpose plant or extracting solution as key component, give full play to these plant materials to the immunoregulation function of human physiological functions by the collocation of the rational formula ratio between various ingredients, make oral liquid have the rapidly and efficiently function of altitude sickness prevention.The formula proportion of various components (W/W) is Tibet Radix Brassicae Rapae natural juice 40%～50%, Fructus Hippophae thibetanae natural juice 4%～5%, Radix Rhei emodi natural juice 4%～5%, Radix Rhodiolae extracting solution 25%～30%, Radix potentillae anserinae extracting solution 4%～5%.
The key component of above-mentioned oral liquid has been selected multiple traditional Tibetan medicine medicine-food two-purpose food that keeps healthy, Tibet Radix Brassicae Rapae (Brassica rapa Linn.) has another name called turnip, circle root (Tibet common name), in Tibetan language, be called " mother girl ", be the distinctive food in high altitude localities, medicine, raise three and use plant.Tibet Radix Brassicae Rapae rich in proteins, crude fibre, calcium, phosphorus, ferrum and vitamin etc. more than 20 are planted the nutritional labeling of needed by human body, what is more important Tibet yuenkanin extract has resisting oxygen lack and can improve body blood coefficient of oxygen utilization with medicine, increase blood confession, Promote immunity, thereby it is relevant to improve the body anaerobic condition.The fruit of Fructus Hippophae thibetanae (Hippophae thibetana) has giddy, the tinnitus that blood circulation promoting and blood stasis dispelling, YIN nourishing, the kidney invigorating, the chest stuffiness relieving are used for anti-initiation on deficiency of liver-blood, the liver-yang, can play by regulating the liver blood function effect of resisting fatigue.Radix Rhei emodi (Rheum australe D.Don---Rheumemodii Wall) Tibetan medicine masterpiece in music is pricked, and is the distinctive medicine food dual purpose plant of Tibet plateau, and Tibetan is commonly called as sour, and is usually that it is edible as fruit.Radix Rhei emodi does not contain composition under contained the rushing down of Chinese herb rhubarb medical material, in the Tibetan medicine mainly in order to treating gastrointestinal inflammation, the gastrointestinal upset that can produce in order to improve altitude sickness, the function of regulating digestive system.Radix Rhodiolae (Rhodiola crenulata) is the medicine food dual purpose plant that the common people of Tibetan commonly use, and mainly grows in the above severe cold of Tibet plateau height above sea level 4500m, anoxia, strong sunshine, pollution-free area.Have heart tonifying, diastole cardiovascular and cerebrovascular vessel, oxygenating effect, help purifying blood, remove refuse in the blood, improve immunity and anti-fatigue ability.Simultaneously also can activate cells in vivo, improve cerebral tissue fatigue is caused the tolerance of anoxia, strengthen cardiac muscle to the resistance of anoxia, regulate blood pressure, make internal body reach balance.Radix potentillae anserinae (Potentilla anserina) Tibet region is called Herba Herminii, Tibetan's food commonly used, Tibetan medicine and pharmacology thinks that Radix potentillae anserinae has invigorating spleen and reinforcing stomach, promoting the production of body fluid to quench thirst, the effect of vigorate qi and replenish the blood, the medicine test shows that Radix potentillae anserinae has the effect that strengthens the smooth muscle wriggling or improve tension force, and can cause that systolic period stops, and has cardiotonic.Above-mentioned oral liquid adds man-hour, and the materials position of various Tibet plant material is respectively: the Tibet Radix Brassicae Rapae is selected plant root, and Fructus Hippophae thibetanae is selected fruit, and Radix Rhei emodi is selected plant roots and stems, and Radix Rhodiolae is selected plant root, and Radix potentillae anserinae adopts plant root.The plant juice that uses be respectively Tibet Radix Brassicae Rapae, Fructus Hippophae thibetanae, Radix Rhei emodi raw material are selected, are cleaned rear with making beating squeeze the juice, centrifugal, filtration, store for subsequent use through the UHT sterilization again, the plant extraction liquid that uses is after Radix Rhodiolae, Radix potentillae anserinae raw material are selected, cleaned, extract vegetation water through micronizing and microwave-subcritical water assisted extraction technique successively, the vegetation water that obtains is through centrifugal, filtration, and the UHT sterilization is stored for subsequent use.
The present invention also provides a kind of method for preparing above-mentioned oral liquid for resisting altitude stress, and its technical scheme is as follows:
A kind of preparation method of above-mentioned oral liquid for resisting altitude stress is characterized in that: first plant juice or plant extraction liquid are mixed in proportion, add necessary adjuvant again, finally by high pressure homogenize, UHT sterilization, packing.
Compared with prior art, the invention has the beneficial effects as follows: (1) oral liquid has the effect of rapid recovery acute high altitude reaction, just the person's that can obviously improve the acute high altitude reaction in about 30min multinomial physiology sign Index can reach the corresponding effect of intravenous drip substantially; (2) the medicine food dual purpose plant raw material selected of oral liquid all is common food materials, the medical material in Tibet plateau common people daily life, and some composition is through edible untoward reaction or the toxic and side effects of not occurring of the mixed collocation of upper a century; (3) oral liquid routinely processing technique production make to store at normal temperatures and guarantee the quality 2 years, product is easy to carry, drink conveniently.
Description of drawings
Fig. 1 is the oral liquor process chart.
The specific embodiment
Below in conjunction with accompanying drawing the preferred embodiments of the present invention are further described.
Embodiment one
Prepare a kind of oral liquid for resisting altitude stress, Fig. 1 is the oral liquor process chart.Concrete grammar is as follows:
1, selection is got the raw materials ready
The Tibet Radix Brassicae Rapae: select the second best in quality Tibet Radix Brassicae Rapae root raw material, after the cleaning successively through making beating squeeze the juice, centrifugal, filter, store for subsequent use through the UHT sterilization again.
Fructus Hippophae thibetanae: select the second best in quality Fructus Hippophae thibetanae fruit, after the cleaning successively through making beating squeeze the juice, centrifugal, filter, store for subsequent use through the UHT sterilization again.
Radix Rhei emodi: select the second best in quality Radix Rhei emodi stem raw material, after the cleaning successively through making beating squeeze the juice, centrifugal, filter, store for subsequent use through the UHT sterilization again.
Radix Rhodiolae: select the second best in quality Radix Rhodiolae root raw material, extract vegetation water through micronizing and microwave-subcritical water assisted extraction technique successively after the cleaning, gained Radix Rhodiolae lixiviating solution is stored for subsequent use through centrifugal, filtration, UHT sterilization; Microwave-subcritical water assisted extraction technique leading indicator is: microwave power 500w, processing time 10min; Take subcritical water as extractant, add on demand in case of necessity α-amylase, solid-to-liquid ratio 1: 10, about 80 ℃ of water temperature, the about 12hr of extraction time, extracting times 3 times.。
Radix potentillae anserinae: select the second best in quality Radix potentillae anserinae root raw material, extract vegetation water through micronizing and microwave-subcritical water assisted extraction technique successively after the cleaning, gained Radix potentillae anserinae lixiviating solution is stored for subsequent use through centrifugal, filtration, UHT sterilization; Microwave-subcritical water assisted extraction technique leading indicator is with the processing of Radix Rhodiolae.
Adjuvant: glucose, sodium chloride, potassium chloride.
2, processing formula
Oral liquid component prescription (W/W): Tibet Radix Brassicae Rapae natural juice 40%～50%, Fructus Hippophae thibetanae natural juice 4%～5%, Radix Rhei emodi natural juice 4%～5%, Radix Rhodiolae extracting solution 25%～30%, Radix potentillae anserinae extracting solution 4%～5%; Glucose 5%, sodium chloride 0.1%, potassium chloride 0.01%.
3, processing technique
The plant juice or the plant extraction liquid that make are mixed in proportion, add again glucose, sodium chloride, potassium chloride, finally by high pressure homogenize, UHT sterilization, packing.
The acute high altitude reaction oral liquid effect that makes drunk by people shows in the certain limit: the acute high altitude reaction person drinks the oral liquid that processing makes can obviously alleviate related symptoms, in about 30min, drinking person is dizzy, headache, nervous, symptom disappear substantially, and most drinking person tachypneas, weak, nauseating, dim eyesight, dizzy symptom disappear substantially; It is decreased heart rate that the physiology sign is improved main manifestations, it is mild to breathe, lip turns red, and the sign performance all is tending towards normal.Physical condition according to drinking person is different, and onset time is slightly different, is effectively alleviated but most drinking person all shows as altitude sickness in drinking the about 30min of oral liquid.
The oral liquid that processing makes in the present embodiment can add first on demand in case of necessity additive and regulate taste again through high pressure homogenize, UHT sterilization, packing.
Embodiment two
The oral liquid for preparing a kind of altitude sickness prevention.Itself and embodiment one something in common no longer repeat, and its difference is processing formula, is specially:
Oral liquid component prescription (W/W): Tibet Radix Brassicae Rapae natural juice 50%, Fructus Hippophae thibetanae natural juice 5%, Radix Rhei emodi natural juice 5%, Radix Rhodiolae extracting solution 30%, Radix potentillae anserinae extracting solution 5%; Glucose 5%, sodium chloride 0.1%, potassium chloride 0.01%.
Claims (3)
1. method for preparing oral liquid for resisting altitude stress is characterized in that: carry out according to following steps:
Step 1, selection are got the raw materials ready
The Tibet Radix Brassicae Rapae: Tibet Radix Brassicae Rapae root raw material, after the cleaning successively through making beating squeeze the juice, centrifugal, filter, store for subsequent use through the UHT sterilization again; Fructus Hippophae thibetanae: the Fructus Hippophae thibetanae fruit, after the cleaning successively through making beating squeeze the juice, centrifugal, filter, store for subsequent use through the UHT sterilization again; Radix Rhei emodi: Radix Rhei emodi stem raw material, after the cleaning successively through making beating squeeze the juice, centrifugal, filter, store for subsequent use through the UHT sterilization again; Radix Rhodiolae: Radix Rhodiolae root raw material, extract vegetation water through micronizing and microwave-subcritical water assisted extraction technique successively after the cleaning, gained Radix Rhodiolae lixiviating solution is stored for subsequent use through centrifugal, filtration, UHT sterilization; Radix potentillae anserinae: Radix potentillae anserinae root raw material, extract vegetation water through micronizing and microwave-subcritical water assisted extraction technique successively after the cleaning, gained Radix potentillae anserinae extract is stored for subsequent use through centrifugal, filtration, UHT sterilization; Adjuvant: glucose, sodium chloride, potassium chloride;
Step 2, processing formula
Oral liquid component prescription (W/W): Tibet Radix Brassicae Rapae natural juice 40%～50%, Fructus Hippophae thibetanae natural juice 4%～5%, Radix Rhei emodi natural juice 4%～5%, Radix Rhodiolae extracting solution 25%～30%, Radix potentillae anserinae extracting solution 4%～5%; Glucose 5%, sodium chloride 0.1%, potassium chloride 0.01%;
Step 3, processing technique
The plant juice or the plant extraction liquid that make are mixed in proportion, add again glucose, sodium chloride, potassium chloride, finally by high pressure homogenize, UHT sterilization, packing.
2. preparation method according to claim 1, it is characterized in that: in described step 2 processing formula, Tibet Radix Brassicae Rapae natural juice weight ratio is 50%, Fructus Hippophae thibetanae natural juice weight ratio is 5%, Radix Rhei emodi natural juice weight ratio is 5%, Radix Rhodiolae extracting solution weight ratio is 30%, and Radix potentillae anserinae extracting solution weight ratio is 5%; Also contain glucose 5%, sodium chloride 0.1%, potassium chloride 0.01%.
3. preparation method according to claim 1 and 2, it is characterized in that: during described step 1 selection is got the raw materials ready, microwave-subcritical water assisted extraction technique leading indicator is: microwave power 500w, processing time 10min, take subcritical water as extractant, solid-to-liquid ratio 1:10,80 ℃ of water temperatures, extraction time 12hr.
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104287001A (en) * | 2013-07-17 | 2015-01-21 | 米玛江才 | Production method of brassica rapa L. anti-hypoxia oral liquid |
| CN104257767B (en) * | 2014-09-19 | 2017-05-17 | 西藏藏真堂藏药产业有限公司 | Method for extracting active ingredients of rheum australe and application thereof |
| CN104288262A (en) * | 2014-10-11 | 2015-01-21 | 中山百鸥医药科技有限公司 | Method for preparing altitude stress resistant medicament |
| CN104274808A (en) * | 2014-10-11 | 2015-01-14 | 中山百鸥医药科技有限公司 | Traditional Chinese medicine composition for anti-altitude stress |
| CN105168308A (en) * | 2015-09-09 | 2015-12-23 | 白玛仁增 | Altitude sickness-resistant compound Tibetan medicine preparation |
| CN106136230A (en) * | 2016-06-28 | 2016-11-23 | 新疆华圣元医药科技有限公司 | Radix Brassicae rapae oral liquid and preparation method thereof |
| CN110338318A (en) * | 2019-01-05 | 2019-10-18 | 西藏屋脊之宝生物科技有限公司 | A kind of health-care beverage and preparation method without pigment essence preservative hormone |
| CN111329907A (en) * | 2020-03-06 | 2020-06-26 | 西南交通大学 | Common turnip composition with anti-hypoxia function and preparation method and application thereof |
| CN115088765A (en) * | 2022-06-17 | 2022-09-23 | 青海省轻工业研究所有限责任公司 | Common turnip and sea buckthorn fruit milk and preparation method thereof |
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