CN102144712B - Platycodon root extract feed additive and preparation method thereof - Google Patents
Platycodon root extract feed additive and preparation method thereof Download PDFInfo
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- CN102144712B CN102144712B CN201010106905.9A CN201010106905A CN102144712B CN 102144712 B CN102144712 B CN 102144712B CN 201010106905 A CN201010106905 A CN 201010106905A CN 102144712 B CN102144712 B CN 102144712B
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Abstract
The invention discloses a platycodon root extract feed additive and a preparation method thereof. The platycodon root extract feed additive is prepared by performing circulating extraction on the platycodon root for multiple times and then mixing the extract and a carrier uniformly. The preparation method comprises the following steps of: crudely extracting the platycodon root; and 2, performing secondary circulating extraction on the residues after the extraction in the step 1, performing spray drying on the extractum obtained in the secondary extraction, and mixing the extractum and the carrier uniformly to prepare the platycodon root extract feed additive. The platycodon root extract feed additive has the functions of releasing lung, eliminating phlegm, releasing throat, evacuating pus and improving animal immunity.
Description
Technical field
The present invention relates to a kind of platycodon root extract feed additive and preparation method thereof, there is a surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, improve the function of animal immunizing power, belong to natural plants additive technology field.
Background technology
Along with the development of China's aquaculture, the disease of all kinds of cultivated animals has become the outstanding problem of restriction industry development.Only, with regard to common communicable disease, its kind is just very complicated, has bacteriosis, parasitic diseases, viral disease etc.Such disease is prevented and treated mainly through the method such as vaccine inoculation, medical treatment at present in aquaculture.
Vaccine control common is at present all only for the specific immune system of animal body, not strong to the specific aim of the cause of disease of other type, and a kind of vaccine can only prevent a kind of disease, and need the antibody generation time being greater than about a week, because its use procedure needs strict use management measure, so vaccine control effect is aborning also very limited.Although there is the vaccine product of One's name is legion in the market, very different, add in use improper use, make the effect of vaccine prevention always bad.Although medical treatment technology is relatively effective, be also current employing mainly prevent mode, its side effect is also very outstanding, the generation of drug resistance and expansion, multi-medicament residual effect, to pollution of environment etc.The use of present chemicals has also received very strict restriction.
Although had Chinese herbal medicine to enter feed addictive ranks at present, be of rude workmanship, majority has been direct pulverization process.Its active ingredient is indefinite, consumption is large, it is slow to absorb, onset is slow, and Chinese herbal medicine extract exactly compensate for above shortcoming, have consumption few, check on clear and definite, act on fast feature.Because resources of Chinese medicinal herb is in natural plants, medicament residue can not be produced, bacterium can not be caused, virus variation, feature free from environmental pollution etc., the effect of alternative medicine additive, antibiotic etc. can be played.Therefore Chinese herb feed additive will be advocated in future in the journey of healthy aquaculture, green cultivation and is had very high research and utilization value.
Summary of the invention
The present invention with natural balloonflower root for raw material, through the processing of science, it can be the nerve of animal, immunity, internal system provides comprehensively potent trophism, blood-enrich, fast quick-recovery and enhancing animal immune system function, increase the mucilage secretion amount of animal body mucous membrane tissue, strengthen the ability of the multiple IG antibody of animal body mucosal secretions, strengthen the activity of all kinds of immunocyte, repair the mucous membrane tissue structure damaged, thus resist various germ efficiently, virus, harmful microbe is invaded, thus reduce the incidence of disease of the common respiratory tract of livestock and poultry and disease of digestive tract.
Technical scheme of the present invention adopts following means to realize to achieve these goals:
A kind of platycodon root extract feed additive and preparation method thereof, described platycodon root extract feed additive comprises extract 2-4 part of the root of balloonflower root, carrier 3-6 part, is made up of with suitable carrier after spray drying treatment through twice alcohol extract the root of balloonflower root.
Present invention also offers a kind of preparation method of platycodon root extract feed additive, concrete steps are as follows:
Step 1, respectively the root of raw material balloonflower root is picked only, brachymemma, cleaning;
Step 2, loaded in alcohol extracting tank by raw material, add 65% ~ 95% ethanol of 3 ~ 6 times of weight, boil 3 ~ 6 hours, steam pressure is 0.4 ~ 0.7MPa, alcohol reflux;
Filter after step 3, first time alcohol extracting, obtain the first filtrate and the first filter residue respectively; Wherein, the first filtrate is by reduced pressure concentration tank recovery ethanol, until the ethanol < 60% reclaimed stops reclaiming, the continuation of the first filtrate concentrates to obtain concentrate;
Step 4, the first filter residue second time add 65% ~ 95% ethanol of 3 ~ 6 times of weight, boil 3 ~ 6 hours, steam pressure 0.4 ~ 0.7MPa, alcohol reflux, until the ethanol < 60% reclaimed stops reclaiming, filter, obtain the second filtrate and the second filter residue respectively, discard the second filter residue;
Step 5, concentrate, the second filtrate mixed and is concentrated into proportion D=0.9 ~ 1.4, obtaining medicinal extract;
Step 6, medicinal extract load container, refrigerate and preserve at 1 ~ 5 DEG C;
Step 7, medicinal extract enter spray dryer, EAT 180 DEG C, and leaving air temp 70 ~ 90 DEG C, obtains Radix Platycodonis extract dry powder;
Namely step 9, extract dry powder obtain a kind of platycodon root extract feed additive after mixing with the carrier be applicable to.
Described carrier is preferably at least one in attapulgite, silica, pine needle meal and maltodextrin.Concentrated reduced pressure concentration or the interlayer concentration tank of being respectively of described concentrate, the first filtrate, the second filtrate concentrates.
The present invention has following obvious advantage and beneficial effect in sum:
1) declare lung to eliminate the phlegm, reduce the animal respiratory disease incidence of disease;
2) generation of animal alimentary canal ulcer and diarrhea is prevented and treated;
3) palatability is strong, improves feed intake;
4) natural, noresidue, have no drug resistance, have no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is illustrated:
A kind of platycodon root extract feed additive, is made up of following parts by weight formula: the extract of balloonflower root root 2 parts; 3 parts, carrier.
A kind of platycodon root extract feed additive and preparation method thereof, preparation process is as follows:
Step 1, respectively the root of raw material balloonflower root is picked only, brachymemma, cleaning;
Step 2, loaded in alcohol extracting tank by raw material, add 65% ~ 95% ethanol of 3 ~ 6 times of weight, boil 3 ~ 6 hours, steam pressure is 0.4 ~ 0.7MPa, alcohol reflux;
Filter after step 3, first time alcohol extracting, obtain the first filtrate and the first filter residue respectively; Wherein, the first filtrate is by reduced pressure concentration tank recovery ethanol, until the ethanol < 60% reclaimed stops reclaiming, the continuation of the first filtrate concentrates to obtain concentrate;
Step 4, the first filter residue second time add 65% ~ 95% ethanol of 3 ~ 6 times of weight, boil 3 ~ 6 hours, steam pressure 0.4 ~ 0.7MPa, alcohol reflux, until the ethanol < 60% reclaimed stops reclaiming, filter, obtain the second filtrate and the second filter residue respectively, discard the second filter residue;
Step 5, concentrate, the second filtrate mixed and is concentrated into proportion D=0.9 ~ 1.4, obtaining medicinal extract;
Step 6, medicinal extract load container, refrigerate and preserve at 1 ~ 5 DEG C;
Step 7, medicinal extract enter spray dryer, EAT 180 DEG C, and leaving air temp 70 ~ 90 DEG C, obtains Radix Platycodonis extract dry powder;
Namely step 9, extract dry powder obtain a kind of platycodon root extract feed additive after mixing with the carrier be applicable to.
Chinese herbal medicine is the natural resources of Chinese medicinal materials in China's traditional Chinese veterinary medicine.Balloonflower root is Araliaceae, another name: RADIX PLATYCODI, RADIX PLATYCODI, RADIX PLATYCODI, baiyao.The medicinal part of balloonflower root is root, and active ingredient is wherein for containing platycodoside.There is a surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, anti-inflammation, the function improving animal immunizing power can be used for bacillary, mycoplasma breathing problem, enteritis etc., green, nontoxic, have no side effect.
The present invention is illustrated below in conjunction with embodiment:
Embodiment 1
2009.07.10----2009.08.10 experimental animal adopted and was bred as later stage DLY ternary pigs in Shanghai Bai Shu breeding demonstration field period.Carry out contrasting interpolation result of the test as follows
| Test index | Test group | Control group | Conspicuousness |
| Daily gain (g) | 855 | 780 | P＜0.05 |
| Daily ingestion amount (g) | 2291 | 2384 | - |
| Feedstuff-meat ratio | 2.68 | 3.01 | P＜0.01 |
| Survival rate (%) | 100 | 97 | - |
| The respiratory tract incidence of disease | 22％ | 34％ | P＜0.05 |
| Diarrhea incidence | 17％ | 26％ | P＜0.05 |
Conclusion:
1. improve feed palatability, improve animal daily ingestion amount, improve adding weight;
2. improve feedstuff-meat ratio, reduce production cost;
3. reduce swinery respiratory tract, the disease of digestive tract incidence of disease, improve survival rate.
During use, can use by spice.During spice, complete feed per ton adds 500 ~ 1000g.
Last it is noted that above embodiment only in order to illustrate the present invention and and unrestricted technical scheme described in the invention; Therefore, although this description with reference to each above-mentioned embodiment to present invention has been detailed description, those of ordinary skill in the art should be appreciated that and still can modify to the present invention or equivalent to replace; And all do not depart from technical scheme and the improvement thereof of the spirit and scope of invention, it all should be encompassed in the middle of right of the present invention.
Claims (1)
1. the preparation method of a platycodon root extract feed additive, described platycodon root extract feed additive comprises the extract of the root of balloonflower root, carrier, it is characterized in that: be made up of following formulation by weight ratio: extract dry powder 2-4 part of the root of balloonflower root, carrier 3-6 part, the preparation method of described platycodon root extract feed additive, preparation process is as follows:
Step 1, respectively the root of raw material balloonflower root is picked only, brachymemma, cleaning;
Step 2, loaded in alcohol extracting tank by raw material, add 65% ~ 95% ethanol of 3 ~ 6 times of weight, boil 3 ~ 6 hours, steam pressure is 0.4 ~ 0.7MPa, alcohol reflux;
Filter after step 3, first time alcohol extracting, obtain the first filtrate and the first filter residue respectively; Wherein, the first filtrate is by reduced pressure concentration tank recovery ethanol, until the ethanol <60% reclaimed stops reclaiming, the continuation of the first filtrate concentrates to obtain concentrate;
Step 4, the first filter residue second time add 65% ~ 95% ethanol of 3 ~ 6 times of weight, boil 3 ~ 6 hours, steam pressure 0.4 ~ 0.7MPa, alcohol reflux, until the ethanol <60% reclaimed stops reclaiming, filters, obtain the second filtrate and the second filter residue respectively, discard the second filter residue;
Step 5, concentrate, the second filtrate mixed and is concentrated into proportion D=0.9 ~ 1.4, obtaining medicinal extract;
Step 6, medicinal extract load container, refrigerate and preserve at 1 ~ 5 DEG C;
Step 7, medicinal extract enter spray dryer, EAT 180 DEG C, and leaving air temp 70 ~ 90 DEG C, obtains Radix Platycodonis extract dry powder;
Namely step 8, extract dry powder obtain a kind of platycodon root extract feed additive after mixing with the carrier be applicable to,
Described carrier is at least one in attapulgite, silica, pine needle meal and maltodextrin, and the simmer down to reduced pressure concentration of described concentrate, the first filtrate, the second filtrate or interlayer concentration tank concentrate.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201010106905.9A CN102144712B (en) | 2010-02-08 | 2010-02-08 | Platycodon root extract feed additive and preparation method thereof |
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| CN201010106905.9A CN102144712B (en) | 2010-02-08 | 2010-02-08 | Platycodon root extract feed additive and preparation method thereof |
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| CN102144712B true CN102144712B (en) | 2015-04-08 |
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| CN103371272B (en) * | 2013-06-28 | 2014-09-10 | 贵州博康生物工程有限公司 | Method for promoting intensive spawning of houseflies and used breeding feed and egg receiving material |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569128A (en) * | 2004-04-23 | 2005-01-26 | 赵子群 | Livestock feedstuff addictive with Chinese medicine for preventing and treating aftosa and its preparation |
| CN101584745A (en) * | 2009-06-29 | 2009-11-25 | 北京大北农科技集团股份有限公司 | Preparation for new antivirus Chinese medicine formulation for animal |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1669460A (en) * | 2004-03-16 | 2005-09-21 | 上海朝翔生物技术有限公司 | Front-anthocyanidin feed addictive |
| KR100631317B1 (en) * | 2005-09-15 | 2006-10-04 | 이용광 | Manufacturing method of nutural feed using medicinal herbs and propolis |
| JP2007151524A (en) * | 2005-12-02 | 2007-06-21 | Nippon Yuki Kk | Agriculture and livestock industry circulative environment maintenance system, and livestock feed, feed additive, useful microorganism immobilizing gel, and fertilizer to be used for the system |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569128A (en) * | 2004-04-23 | 2005-01-26 | 赵子群 | Livestock feedstuff addictive with Chinese medicine for preventing and treating aftosa and its preparation |
| CN101584745A (en) * | 2009-06-29 | 2009-11-25 | 北京大北农科技集团股份有限公司 | Preparation for new antivirus Chinese medicine formulation for animal |
Non-Patent Citations (1)
| Title |
|---|
| 金锡九,等.桔梗乙醇提取物的急性及蓄积性毒性试验.《饲料博览》.2007,(第19期),对比文件1第51页第2、3段及第52页第1.3.1节. * |
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