CN102144728A - Preparation method of honeysuckle extract feed additive - Google Patents
Preparation method of honeysuckle extract feed additive Download PDFInfo
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- CN102144728A CN102144728A CN2010101068709A CN201010106870A CN102144728A CN 102144728 A CN102144728 A CN 102144728A CN 2010101068709 A CN2010101068709 A CN 2010101068709A CN 201010106870 A CN201010106870 A CN 201010106870A CN 102144728 A CN102144728 A CN 102144728A
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Abstract
The invention discloses a preparation method of a honeysuckle extract feed additive. The preparation method comprises the following steps of: collecting the stalks, leaves and flowers of the honeysuckle and clearing the stalks, leaves and flowers of the honeysuckle; putting the raw materials into an ethanol extracting tank; adding ethanol; boiling; performing ethanol reflux; filtering after extracting alcohol for the first time to obtain filtrate and filter residue respectively; allowing the filtrate to pass through a vacuum pressure reduction concentration tank to recover the ethanol; concentrating the concentrated liquid continuously to obtain concentrated solution; adding ethanol into the filter residue for the second time; boiling; performing ethanol reflux; filtering to obtain first filtrate and filter residue; adding water into the filter residue; boiling; filtering to obtain second filtrate and filter residue respectively; discarding the filter residue; mixing and concentrating the concentrated solution, the first filtrate and the second filtrate to obtain honeysuckle extractum; putting the extractum into a container to refrigerate and store; and drying the extractum to obtain the honeysuckle extract dried powder. The honeysuckle extract feed additive has the advantages of avoidance of medicament residue, safety and harmlessness. The honeysuckle extract feed additive has the effects of clearing heat, relieving toxin, cooling and dissipating heat, has broad spectrum antibiotic and antioxidant effects and can be applied to preparation process of animal feed additives.
Description
Technical field
The present invention relates to a kind of preparation method of feed addictive, relate in particular to the preparation method of a kind of animal, belong to the natural plant feed additives technical field with the Honegsukle flower P.E feed addictive.
Background technology
Along with the continuous development of China's aquaculture, the disease of all kinds of cultivated animals has become the outstanding problem of restriction industry development.Only with regard to common communicable disease, its kind is just very complicated, bacteriosis is arranged, parasitic diseases, viral disease or the like.Equally, the disease that all kinds are propagated by respiratory tract, alimentary canal is also deep is perplexing the various places raiser, and respiratory tract and disease of digestive tract and disease of digestive tract threaten the pig industry of China day by day, to the stage that must solve.In aquaculture, mainly prevent and treat such disease at present by methods such as vaccine inoculation, medical treatments.
Common vaccine control all is a specific immunity system at animal body at present, specific aim to the cause of disease of other type is not strong, and a kind of vaccine can only prevent a kind of disease, and need be greater than the antibody generation time about a week, because its use needs strict use and management measure, so vaccine control effect aborning is also very limited.Though the vaccine product of One's name is legion is arranged in the market, very different, add improper use in use, make that the effect of vaccine prevention is bad always.Though the medical treatment technology is more effective, also be the mode that mainly prevents of current employing, its side effect is also very outstanding, chemical sproof generation and expansion, the multiple noresidue effect of wanting is to pollution of environment or the like.The use of chemicals now also has been subjected to very strict restriction.
Though had Chinese herbal medicine to enter the feed addictive ranks at present, be of rude workmanship, most be direct pulverization process.Its active ingredient is indeterminate, consumption big, it is slow to absorb, active ingredient is difficult for absorbing, and onset is slow, and Chinese herbal medicine extract has exactly remedied above shortcoming, has the advantages that consumption is few, target organ clear and definite, effect is fast.Because resources of Chinese medicinal herb is in natural plants, can not produce medicament residue, can not cause bacterium, virus variation, free from environmental pollution etc. characteristics, can play the effect of alternative medicine additive, antibiotic etc.
Summary of the invention
The objective of the invention is to,, be used for animal heat-clearing, detoxifcation, cool breeze heat radiation, have broad-spectrum antiseptic and oxidation resistant effect by a kind of preparation method of Honegsukle flower P.E feed addictive is provided.
The present invention adopts following technological means to realize:
Gather stem, leaf, the flower of honeysuckle and choose clean;
Above-mentioned raw materials is packed in the alcohol extracting jar, add 60%～95% ethanol of 3～6 times of amounts, boiled 1～3 hour, steam pressure is 0.4MPa～0.7MPa, alcohol reflux;
Carry for the first time the alcohol back and filter, respectively filtrate and filter residue, filtrate is reclaimed ethanol by the decompression concentration tank, stop to reclaim until ethanol＜60% that reclaims, filtrate continuation concentrate concentrate;
Filter residue adds 60%～95% ethanol of 3～6 times of amounts for the second time, boils 1～3 hour, and steam pressure is 0.4MPa～0.7MPa, and alcohol reflux stops to reclaim until ethanol＜60% that reclaims, and filters the win filtrate and first filter residue;
Filter residue adds 6～9 times of water gagings, boils 1～3 hour, and steam pressure is 1MPa～1.3MPa, filters, and obtains second filtrate and second filter residue respectively, discards second filter residue;
Concentrate, first filtrate, second filtrate mixed and be concentrated into D=0.8～1.5 promptly get honeysuckle concrete;
The medicinal extract container of packing into refrigerates in 1 ℃～5 ℃ and preserves down;
The medicinal extract spray dryer of packing into, EAT is 180 ℃～195 ℃, leaving air temp is 70 ℃～90 ℃, promptly gets Honegsukle flower P.E dry powder.
Honegsukle flower P.E dry powder promptly gets a kind of Honegsukle flower P.E feed addictive after mixing with the carrier that is fit to.
Described carrier is for being a kind of in pine needle meal, attapulgite, silica, the maltodextrin at least.
Aforesaid concentrate, first filtrate, second filtrate concentrated is respectively that decompression concentrates or the interlayer concentration tank concentrates.
The present invention also provides a kind of using method of Honegsukle flower P.E feed addictive, and the Honegsukle flower P.E feed addictive that adopts above-mentioned preparation method to make adds the 100g-200g proportioning by complete feed per ton and uses.
Because adopt above-mentioned technical scheme, the present invention has following beneficial effect:
Owing to adopt pure plant extract, the feed addictive that preparation method of the present invention produces has the effect of avoiding medicament residue, safe and harmless, heat-clearing, detoxifcation, cool breeze heat radiation, has broad-spectrum antiseptic and oxidation resistant effect.
Description of drawings
Fig. 1 is the preparation method's of Honegsukle flower P.E feed addictive of the present invention process chart.
The specific embodiment
As shown in Figure 1, the preparation method of Honegsukle flower P.E feed addictive of the present invention utilizes extraction process to extract active ingredient in the honeysuckle to prepare by a certain percentage with pine needle meal, plant plait wood powder etc. and mix.2 parts of Honegsukle flower P.Es; 3 parts in carrier.
The main technique step comprises:
Gather stem, leaf, the flower of honeysuckle and choose clean;
Above-mentioned raw materials is packed in the alcohol extracting jar, add 60%～95% ethanol of 3～6 times of amounts, boiled 1～3 hour, steam pressure is 0.4MPa～0.7MPa, alcohol reflux;
Carry for the first time the alcohol back and filter, respectively filtrate and filter residue, filtrate is reclaimed ethanol by the decompression concentration tank, stop to reclaim until ethanol＜60% that reclaims, filtrate continuation concentrate concentrate;
Filter residue adds 60%～95% ethanol of 3～6 times of amounts for the second time, boils 1～3 hour, and steam pressure is 0.4MPa～0.7MPa, and alcohol reflux stops to reclaim until ethanol＜60% that reclaims, and filters the win filtrate and first filter residue;
First filter residue adds 6～9 times of water gagings, boils 1～3 hour, and steam pressure is 1MPa～1.3MPa, filters, and obtains second filtrate and second filter residue respectively, discards second filter residue;
Concentrate, first filtrate, second filtrate mixed and be concentrated into D=0.8～1.5 promptly get honeysuckle concrete;
The medicinal extract container of packing into refrigerates in 1 ℃～5 ℃ and preserves down;
The medicinal extract spray dryer of packing into, EAT is 180 ℃～195 ℃, leaving air temp is 70 ℃～90 ℃, promptly gets Honegsukle flower P.E dry powder.
Honegsukle flower P.E dry powder promptly gets a kind of Honegsukle flower P.E feed addictive after mixing with the carrier that is fit to.
The active ingredient of Honegsukle flower P.E: chlorogenic acid, in addition, also contain flavonoids, triterpenes etc.
Product efficacy of the present invention: heat-clearing, detoxifcation, cool breeze heat radiation, broad-spectrum antiseptic and oxidation resistant effect.
Many evidences are used Chinese herbal medicine and not only can be cured the disease by individuality, and can colony's control.And adapt to intensification, the needs of large-scale breeding.The most important thing is to have solved the insurmountable medicament residue problems of medicated premix such as antibiotic, hormone.Meet the nuisanceless animal husbandry of development, produce the feed addictive standard of green livestock products, but also have antibiotic, the unrivaled advantage of hormone medicine additive.
Specify the present invention below in conjunction with embodiment:
2008.06.20----2008.07.20 during test at the vast and boundless biotechnology research of Shanghai farming institute test site, experimental animal adopts breeds later stage DLY ternary pig.It is as follows to have carried out contrast interpolation result of the test
| Test index | Test group | Control group | Conspicuousness |
| Daily gain (g) | 851 | 792 | P＜0.05 |
| Daily ingestion amount (g) | 2286 | 2340 | - |
| Feedstuff-meat ratio | 2.7 | 3.12 | P＜0.01 |
| Survival rate (%) | 100 | 96 | - |
| The diarrhea incidence of disease | 14％ | 25％ | P＜0.01 |
| The respiratory tract incidence of disease | 22％ | 34％ | P＜0.05 |
| The blue otopathy incidence of disease | 16％ | 27％ | P＜0.05 |
Conclusion:
1. strengthen animal body immunologic function, disease-resistant growth-promoting;
2. reduce the swinery respiratory tract and the disease of digestive tract incidence of disease, improve survival rate;
3. reduce the blue otopathy incidence of disease, improve productivity effect.
4. natural, noresidue, have no drug resistance, have no side effect.
During use, can drink water also can spice.During drinking-water, water per ton adds 500g; During spice, complete feed per ton adds 500～1000g.
It should be noted that at last: above embodiment only in order to the explanation the present invention and and unrestricted technical scheme described in the invention; Therefore, although this specification has been described in detail the present invention with reference to each above-mentioned embodiment,, those of ordinary skill in the art should be appreciated that still and can make amendment or be equal to replacement the present invention; And all do not break away from the technical scheme and the improvement thereof of the spirit and scope of invention, and it all should be encompassed in the middle of the claim scope of the present invention.
Claims (2)
1. the preparation method of a Honegsukle flower P.E feed addictive is characterized in that: be divided into following steps:
Step 1: stem, leaf, the flower of gathering honeysuckle choose clean;
Step 2: above-mentioned raw materials is packed in the alcohol extracting jar, add 60%～95% ethanol of 3～6 times of amounts, boiled 1～3 hour, steam pressure is 0.4MPa～0.7MPa, alcohol reflux;
Step 3: carry for the first time the alcohol back and filter, divide other filtrate and filter residue, filtrate is reclaimed ethanol by the decompression concentration tank, stop to reclaim until ethanol＜60% that reclaims, filtrate continuation concentrate concentrate;
Step 4: filter residue adds 60%～95% ethanol of 3～6 times of amounts for the second time, boils 1～3 hour, and steam pressure is 0.4MPa～0.7MPa, and alcohol reflux stops to reclaim until ethanol＜60% that reclaims, and filters the win filtrate and first filter residue;
Step 5: first filter residue adds 6～9 times of water gagings, boils 1～3 hour, and steam pressure is 1MPa～1.3MPa, filters, and obtains second filtrate and second filter residue respectively, discards second filter residue;
Step 6: concentrate, first filtrate, second filtrate mixed and be concentrated into D=0.8～1.5 promptly getting honeysuckle concrete;
Step 7: the medicinal extract container of packing into refrigerates in 1 ℃～5 ℃ and preserves down;
Step 8: the medicinal extract spray dryer of packing into, EAT is 180 ℃～195 ℃, leaving air temp is 70 ℃～90 ℃, promptly gets extract dry powder.
Step 9: Honegsukle flower P.E dry powder promptly gets a kind of Honegsukle flower P.E feed addictive after mixing with the carrier that is fit to.
2. the preparation method of a kind of Honegsukle flower P.E feed addictive according to claim 1 is characterized in that: described concentrate, first filtrate, second filtrate concentrated is respectively that decompression concentrates or the interlayer concentration tank concentrates.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101068709A CN102144728A (en) | 2010-02-08 | 2010-02-08 | Preparation method of honeysuckle extract feed additive |
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| CN2010101068709A CN102144728A (en) | 2010-02-08 | 2010-02-08 | Preparation method of honeysuckle extract feed additive |
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| CN102144728A true CN102144728A (en) | 2011-08-10 |
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| CN2010101068709A Pending CN102144728A (en) | 2010-02-08 | 2010-02-08 | Preparation method of honeysuckle extract feed additive |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106561983A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | Decay-proof and mildew-resistant honeysuckle stem and leaf feed additive, and preparation method and application thereof |
| CN106562100A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | Feed additive for preventing and treating diseases of aquatic organisms and feed for aquatic organisms, and preparation methods thereof |
| CN106562078A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | A honeysuckle flower stem and leaf feed additive capable of preventing and treating poultry bacterium and virus infectious diseases, a preparing method thereof and applications of the feed additive |
| CN106562037A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | Honeysuckle stem and leaf feed additive for preventing and treating pig intestinal tract infectious diseases and improving feed utilization ratio as well as preparation method and application thereof |
| CN107361204A (en) * | 2017-08-14 | 2017-11-21 | 胡玉涛 | The preparation method and animal feed of a kind of honeysuckle extract feed additive |
| CN108157288A (en) * | 2018-01-30 | 2018-06-15 | 广西东兰县隘洞拉社通达种养专业合作社 | The cultural method of one broad sow |
-
2010
- 2010-02-08 CN CN2010101068709A patent/CN102144728A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 吴良柱: "畜禽常用的中草药饲料添加剂", 《湖南农业》 * |
| 张艳丽等: "金银花中绿原酸提取工艺的正交试验研究", 《唐山学院学报》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106561983A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | Decay-proof and mildew-resistant honeysuckle stem and leaf feed additive, and preparation method and application thereof |
| CN106562100A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | Feed additive for preventing and treating diseases of aquatic organisms and feed for aquatic organisms, and preparation methods thereof |
| CN106562078A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | A honeysuckle flower stem and leaf feed additive capable of preventing and treating poultry bacterium and virus infectious diseases, a preparing method thereof and applications of the feed additive |
| CN106562037A (en) * | 2016-09-13 | 2017-04-19 | 河北京阳生物医药科技有限公司 | Honeysuckle stem and leaf feed additive for preventing and treating pig intestinal tract infectious diseases and improving feed utilization ratio as well as preparation method and application thereof |
| CN107361204A (en) * | 2017-08-14 | 2017-11-21 | 胡玉涛 | The preparation method and animal feed of a kind of honeysuckle extract feed additive |
| CN108157288A (en) * | 2018-01-30 | 2018-06-15 | 广西东兰县隘洞拉社通达种养专业合作社 | The cultural method of one broad sow |
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Application publication date: 20110810 |