CN102133345A - Medicament for treating nasal polyp, nasosinusitis and acute and chronic rhinitis and preparation method thereof - Google Patents
Medicament for treating nasal polyp, nasosinusitis and acute and chronic rhinitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating nasal polyp, nasosinusitis and acute and chronic rhinitis, which is mainly prepared from pangolin scales, tall gastrodia tuber, weeping forsythia, golden thread and figwort root according to a weight ratio. The medicament has the effects of clearing heat and purging intense heat, resisting bacteria, diminishing inflammation and cooling blood, has good curative effect on the nasal polyp, the nasosinusitis and the acute and chronic rhinitis and rhinitis and nasal obstruction, and has high cure rate.
Description
Technical field
The present invention relates to a kind of rhinitis that nasal polyp, sinusitis, acute and chronic rhinitis, hypertrophic rhinitis, atrophic rhinitis, allergic rhinitis and various unknown cause cause, medicine of nasal obstruction for the treatment of, belong to the field of Chinese medicines.
Background technology
Sinusitis, nasal polyp and various rhinitis are one of a kind of commonly encountered diseases frequently-occurring diseases, and generation is all arranged throughout the year, and winter is careful especially.The Excreta that polyp and inflammation cause is stopped up nasal cavity, causes respiratory disorder, patient's headache, dizziness, and misery influences normal life and sleep unbearably.At present, the doctor trained in Western medicine for the treatment of this type of is used the injection or the tablet symptomatic treatment of anti-inflammatory type more, but also can only be to cure the symptoms, not the disease, and does not reach the effect of radical cure.
Summary of the invention
Therefore people to curative effect preferably the Chinese medicine medicine have great demand, so far, also do not find about relevant report of the present invention, the inventor is through repeatedly development test, and through a large amount of clinical verifications, finally various rhinitis, polypous Chinese medicine medicine are treated in working out of success, thereby have finished the present invention.
Purpose of the present invention just provides a kind of medicine for the treatment of nasal polyp, sinusitis, acute and chronic rhinitis and various rhinitis, nasal obstruction.
Another object of the present invention has just provided the preparation method of this medicine.
Medicine selection Squama Manis of the present invention, Rhizoma Gastrodiae, Bombyx Batryticatus, Fructus Forsythiae, Rhizoma Coptidis, Radix Scrophulariae, Radix Angelicae Sinensis, Rhizoma Arisaematis (processed), Rhizoma Chuanxiong, Borneolum Syntheticum, Oleum Sesami ten crude drug simply make up, make each medicine produce synergism these drug regimens, thereby can effectively treat rhinitis, the nasal obstruction that nasal polyp, sinusitis, acute and chronic rhinitis, hypertrophic rhinitis, atrophic rhinitis, allergic rhinitis and other various unknown causes cause.Wherein select for use Squama Manis to be because its nature and flavor are salty, liver, stomach warp are gone in cold, and the routed carbuncle of detumescence is arranged, and it is active to search wind, the function of the stimulating milk secretion of stimulating the menstrual flow, and it is swollen to control the carbuncle skin ulcer, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external hemostasis.Select for use Rhizoma Gastrodiae to be because its nature and flavor are sweet, flat, go into Liver Channel, endogenous wind stopping is arranged, the function of arresting convulsion is controlled dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia, aphasia, Xiao Jing Epilepsy wind symptom.Select for use Bombyx Batryticatus to be because its nature and flavor suffering is salty, flat, go into liver, lung, stomach warp, expelling wind to relieve convulsion is arranged, the function of dissipating phlegm and resolving masses is controlled apoplectic aphasia ， Jing Epilepsy, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis.Selecting Fructus Forsythiae for use is because its nature and flavor hardship, and the heart, liver, gallbladder meridian are gone in cold, and heat clearing away is arranged, detoxifcation, eliminating stagnation, the repercussive function, control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Select for use Rhizoma Coptidis to be because its nature and flavor hardship is cold, go into the heart, liver, stomach, large intestine channel, pathogenic fire purging is arranged, dampness, detoxifcation, parasiticidal function, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis is told, nosebleed, hematochezia, quenches one's thirst infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select for use Radix Scrophulariae to be because its nature and flavor hardship is salty, lung, kidney channel are gone in cold, and YIN nourishing is arranged, pathogenic fire reducing, and relieving restlessness, the antidotal function is controlled the calentura excessive thirst, sends out speckle, the hectic fever due to YIN-deficiency consumptive fever, it is not peaceful to sleep night, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Selecting Radix Angelicae Sinensis for use is that temperature is gone into the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down.Select Rhizoma Arisaematis (processed) for use, the different name Rhizoma Arisaematis (processed) is because of its nature and flavor hardship, suffering, and temperature is poisonous, returns lung, liver, spleen channel, drying dampness to eliminate phlegm is arranged, expelling wind and relieving convulsion, the function of mass dissipating and swelling eliminating is controlled the pertinacious phlegm cough, dizziness due to wind-phlegm, and middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Selecting Rhizoma Chuanxiong for use is because its nature and flavor suffering, and temperature is gone into liver, gallbladder meridian, and activating QI to alleviate the depression is arranged, dispeiling pathogenic wind and removing dampness, and the function of promoting blood circulation and stopping pain is controlled air-cooled headache and is revolved dizzyly, and the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation stop block pain, ulcer sores.Select for use Borneolum Syntheticum to be because its nature and flavor are arduous, the heart, lung meridian are gone in cold, and logical all keys are arranged, the stagnated fire of loosing, and removing nebula makes eye bright, the function of reducing swelling and alleviating pain is controlled the apoplexy locked mouth, calentura coma ， Jing Epilepsy expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, conjunctivitis, enterobiasis.Select for use Oleum Sesami to be because its nature and flavor are sweet, meridian of Hand-YANG MING is gone in cold, and moistening dryness for relaxing bowels is arranged, detoxifcation, and the function of granulation promoting is controlled the dryness of the intestine constipation, ascarid, abdominal pain due to retention of food, skin ulcer is swollen, ulcer, scabies, chapped skin.
The consumption of drug component of the present invention is also groped to sum up to draw through the inventor in a large number, and each amounts of components all has curative effect preferably in following weight range:
Squama Manis 20-30 gram Rhizoma Gastrodiaes 30-40 gram Bombyx Batryticatus 10-15 grams
Fructus Forsythiae 30-40 gram Rhizoma Coptidis 10-20 gram Radix Scrophulariaes 30-35 grams
Radix Angelicae Sinensis 20-30 is restrained Rhizoma Arisaematis 20-25 gram Rhizoma Chuanxiongs 25-35 grams
Borneolum Syntheticum 10-15 gram Oleum Sesami 1500-1600 grams
Be preferably:
Squama Manis 26 gram Rhizoma Gastrodiaes 35 gram Bombyx Batryticatus 12 grams
Fructus Forsythiae 35 gram Rhizoma Coptidis 18 gram Radix Scrophulariaes 32 grams
Radix Angelicae Sinensis 26 is restrained Rhizoma Arisaematis 21 gram Rhizoma Chuanxiongs 30 grams
Borneolum Syntheticum 12 gram Oleum Sesami 1500 grams
Main embodiment
The preparation method of medicine of the present invention is as follows:
One, get the raw materials ready:
1, Squama Manis: get the Squama Manis sheet of choosing clean, size is separately put sand and is fried in the pot to easily, adds the Squama Manis sheet, fries to heaving when being golden yellow, takes out, and sifts out sand, cools;
2, Rhizoma Gastrodiae: choose decontamination, size shelves separately are soaked in water to seventy percent saturating, pull out, dry in the air slightly, and profit is even to inside and outside humidity again, and section is dried;
3, Bombyx Batryticatus: choose the silk hair, clean dirt, dry;
4, Fructus Forsythiae: choose clean impurity, stranding is opened, and removes discarding stalk;
5, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section is dried in the shade;
6, Radix Scrophulariae: choose clean impurity, remove removing LU, clean running through, section is dried;
7, Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air slightly to inside and outside humidity when suitable, and section is dried;
8, Rhizoma Arisaematis (processed): get the Rhizoma Arisaematis of choosing clean, soak with cold water and float, avoid Exposure to Sunlight, change water every day 2-3 times, float when playing foam, every Rhizoma Arisaematis adds 2 jin of Alumens for 100 jin, soak after one month, continue to change water, till mouth is tasted no spicy sense, pull out, evenly spread in the container layer by layer, add water logging and do not have with fresh ginger-chip and Alumen, through 3-4 weeks, pour pan boiling again into to the interior no white heart, take out, choose Rhizoma Zingiberis, dry in the air to sixty percent and do; Cut into slices behind the moistening, dry, every day, 100 jin of Rhizoma Arisaematis were with 25 jin of fresh gingers, 12.5-25 jin of Bai Fan;
9, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
10, Borneolum Syntheticum: select the high-quality Borneolum Syntheticum, grind;
11, Oleum Sesami: select high-quality Oleum Sesami.
Two, preparation
1, the Oleum Sesami of described weight is poured into extracted when heating to 130-180 ℃ in the pot, it is fried earlier Squama Manis to be put into pot;
2, treat that Squama Manis in the pot is expanded after, it is fried to deceiving a burnt shape again the Rhizoma Gastrodiae of described weight, Bombyx Batryticatus, Fructus Forsythiae, Rhizoma Coptidis, Radix Scrophulariae, Radix Angelicae Sinensis, Rhizoma Arisaematis (processed), Rhizoma Chuanxiong to be put into pot;
When 3, naturally cooling to 40-50 ℃, the adding Borneolum Syntheticum also stirs, and is cooled to room temperature after-filtration medicinal residues, and the packing bottle packages spare.
Medicine of the present invention has heat clearing away, pathogenic fire purging, and antiinflammatory, antibiotic, the function of removing heat from blood is used for the treatment of nasal polyp, sinusitis, acute and chronic rhinitis and other various rhinitis, nasal obstruction good effect, the cure rate height.
Below further set forth the beneficial effect of medicine of the present invention by testing example.
The rhinitis that Drug therapy nasal polyp of the present invention, sinusitis, acute and chronic rhinitis, hypertrophic rhinitis, atrophic rhinitis, allergic rhinitis and a variety of causes cause, the clinical observation material of nasal obstruction.
1, physical data:
Accept out-patient's 560 examples for medical treatment, wherein male 293 examples, women 267 examples, 3-10 years old 157 age people, 11-20 years old 108 people, 21-30 years old 96 people, 31-40 years old 73 people, 41-50 years old 69 people, 57 people more than 50 years old.
2, diagnostic criteria:
Light-duty inflammation: both sides replacing property of nasal cavity obstruction, rhinorrhea with clear discharge, breathing is obstructed, and suffers from cold and increases the weight of, the influence sleep.
Heavy inflammation: the bilateral nasal cavity stops up for a long time, and dyspnea, nose flow dense tears, sees distinguished and admirable tear, often breathes by the oral cavity, and with headache, feeling of fullness in the head seriously influences sleep.
3, Therapeutic Method:
Adopt spray bottle to spray to nasal cavity, spray twice every day three times at every turn, or two of each collunariums, dripped three times in 1st, 7 days is a course of treatment, three courses of treatment of logotype.
4, efficacy assessment standard;
Produce effects: various inflammation are breathed unimpeded through the treatment posterula, focal symptom disappears, and recover normal, observe 6 months no recidivists.
Take a turn for the better: the nasal obstruction phenomenon takes a turn for the better, and sx is breathed normal substantially.
Invalid: as not reach improvement standard person.
5, therapeutic outcome: (seeing the following form)
In the treatment of above three courses of treatment, with Drug therapy nasal polyp patient 30 examples of the present invention, produce effects 23 examples, 5 examples that take a turn for the better, invalid 2 examples, obvious effective rate is 76.66%, and total effective rate is 93.32%; Treatment sinusitis patient 130 examples, produce effects 109 examples, 18 examples that take a turn for the better, invalid 3 examples, obvious effective rate is 83.84%, total effective rate is 97.70%; Treatment acute and chronic rhinitis patient 142 examples, produce effects 122 examples, 15 examples that take a turn for the better, invalid 5 examples, obvious effective rate is 85.92%, total effective rate is 96.48%; Treatment hypertrophic rhinitis patient 84 examples, produce effects 68 examples, 9 examples that take a turn for the better, invalid 7 examples, obvious effective rate is 80.95%, total effective rate is 91.67%; Treatment atrophic rhinitis patient 73 examples, produce effects 66 examples, 3 examples that take a turn for the better, invalid 4 examples, obvious effective rate is 90.41%, total effective rate is 94.52%; Treatment of allergic rhinitis patient's 59 examples, produce effects 51 examples, 6 examples that take a turn for the better, invalid 2 examples, obvious effective rate is 86.44%, total effective rate is 96.62%; Treatment rhinitis snuffles patient 42 examples, produce effects 37 examples, 4 examples that take a turn for the better, invalid 1 example, obvious effective rate is 88.10%, total effective rate is 97.62%.
Claims (3)
1. medicine for the treatment of nasal polyp sinusitis acute and chronic rhinitis, it is characterized in that: it is to be made by the crude drug in the following weight range:
Squama Manis 20-30 gram Rhizoma Gastrodiaes 30-40 gram Bombyx Batryticatus 10-15 grams
Fructus Forsythiae 30-40 gram Rhizoma Coptidis 10-20 gram Radix Scrophulariaes 30-35 grams
Radix Angelicae Sinensis 20-30 is restrained Rhizoma Arisaematis 20-25 gram Rhizoma Chuanxiongs 25-35 grams
Borneolum Syntheticum 10-15 gram Oleum Sesami 1500-1600 grams.
2. the medicine of treatment nasal polyp sinusitis acute and chronic rhinitis according to claim 1, it is characterized in that: the consumption of described crude drug is:
Squama Manis 26 gram Rhizoma Gastrodiaes 35 gram Bombyx Batryticatus 12 grams
Fructus Forsythiae 35 gram Rhizoma Coptidis 18 gram Radix Scrophulariaes 32 grams
Radix Angelicae Sinensis 26 is restrained Rhizoma Arisaematis 21 gram Rhizoma Chuanxiongs 30 grams
Borneolum Syntheticum 12 gram Oleum Sesami 1500 grams.
3. according to the preparation method of claim 1 or 2 described medicines, it is characterized in that: it comprises the steps:
(1) gets the raw materials ready
(1) Squama Manis: get the Squama Manis sheet of choosing clean, size is separately put sand and is fried in the pot to easily, adds the Squama Manis sheet, fries to heaving when being golden yellow, takes out, and sifts out sand, cools;
(2) Rhizoma Gastrodiae: choose decontamination, size shelves separately are soaked in water to seventy percent saturating, pull out, dry in the air slightly, and profit is even to inside and outside humidity again, and section is dried;
(3) Bombyx Batryticatus: choose the silk hair, clean dirt, dry;
(4) Fructus Forsythiae: choose clean impurity, stranding is opened, and removes discarding stalk;
(5) Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section is dried in the shade;
(6) Radix Scrophulariae: choose clean impurity, remove removing LU, clean running through, section is dried;
(7) Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air slightly to inside and outside humidity when suitable, and section is dried;
(8) Rhizoma Arisaematis (processed): get the Rhizoma Arisaematis of choosing clean, soak with cold water and float, avoid Exposure to Sunlight, change water every day 2-3 times, float when playing foam, every Rhizoma Arisaematis adds 2 jin of Alumens for 100 jin, soak after one month, continue to change water, till mouth is tasted no spicy sense, pull out, evenly spread in the container layer by layer, add water logging and do not have with fresh ginger-chip and Alumen, through 3-4 weeks, pour pan boiling again into to the interior no white heart, take out, choose Rhizoma Zingiberis, dry in the air to sixty percent and do; Cut into slices behind the moistening, dry, every day, 100 jin of Rhizoma Arisaematis were with 25 jin of fresh gingers, 12.5-25 jin of Bai Fan;
(9) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
(10) Borneolum Syntheticum: select the high-quality Borneolum Syntheticum, grind;
(11) Oleum Sesami: select high-quality Oleum Sesami;
(2) preparation
(1) Oleum Sesami of described weight is poured into extracted when heating to 130-180 ℃ in the pot, it is fried earlier Squama Manis to be put into pot;
(2) treat that Squama Manis in the pot is expanded after, it is fried to deceiving a burnt shape again the Rhizoma Gastrodiae of described weight, Bombyx Batryticatus, Fructus Forsythiae, Rhizoma Coptidis, Radix Scrophulariae, Radix Angelicae Sinensis, Rhizoma Arisaematis (processed), Rhizoma Chuanxiong to be put into pot;
When (3) naturally cooling to 40-50 ℃, the adding Borneolum Syntheticum also stirs, and is cooled to room temperature after-filtration medicinal residues, the packing bottle.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100671055A CN102133345B (en) | 2011-03-21 | 2011-03-21 | Medicament for treating nasal polyp, nasosinusitis and acute and chronic rhinitis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011100671055A CN102133345B (en) | 2011-03-21 | 2011-03-21 | Medicament for treating nasal polyp, nasosinusitis and acute and chronic rhinitis and preparation method thereof |
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| CN102133345A true CN102133345A (en) | 2011-07-27 |
| CN102133345B CN102133345B (en) | 2012-04-18 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772539A (en) * | 2012-07-31 | 2012-11-14 | 潘颜芳 | Tincture medicine for treating deficiency-cold rhinopolypus |
| CN104546969A (en) * | 2013-10-26 | 2015-04-29 | 张福增 | Formulas and using method of drug for treating rhinopolypus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101336975A (en) * | 2008-08-13 | 2009-01-07 | 赵建良 | Traditional Chinese medicine ointment for treating dermatophytosis |
| CN101675973A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Heat-clearing and detoxifying phlegm-reducing and masses-resolving traditional Chinese medicine composition |
-
2011
- 2011-03-21 CN CN2011100671055A patent/CN102133345B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101336975A (en) * | 2008-08-13 | 2009-01-07 | 赵建良 | Traditional Chinese medicine ointment for treating dermatophytosis |
| CN101675973A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Heat-clearing and detoxifying phlegm-reducing and masses-resolving traditional Chinese medicine composition |
Non-Patent Citations (4)
| Title |
|---|
| 《开卷有益求医问药》 19980228 刘国应 中医治疗慢性鼻窦炎新方（上） 26-27 1-3 , 第2期 * |
| 《开卷有益求医问药》 19980228 刘国应 中医治疗慢性鼻窦炎新方（上） 26-27 1-3 , 第2期 2 * |
| 《江苏中医》 20000831 耿引循 耿鉴庭先生治疗鼻病十二法 42-44 1-3 第21卷, 第8期 * |
| 《江苏中医》 20000831 耿引循 耿鉴庭先生治疗鼻病十二法 42-44 1-3 第21卷, 第8期 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772539A (en) * | 2012-07-31 | 2012-11-14 | 潘颜芳 | Tincture medicine for treating deficiency-cold rhinopolypus |
| CN102772539B (en) * | 2012-07-31 | 2016-02-17 | 富阳原野生物科技有限公司 | A kind of tincture dose medicament for the treatment of asthenic cold type nasal polyp |
| CN104546969A (en) * | 2013-10-26 | 2015-04-29 | 张福增 | Formulas and using method of drug for treating rhinopolypus |
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| CN102133345B (en) | 2012-04-18 |
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