CN102132930B - Multidimensional nutrition instant decoction and method for preparing same - Google Patents
Multidimensional nutrition instant decoction and method for preparing same Download PDFInfo
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Abstract
The invention discloses a multidimensional nutrition instant decoction which comprises compositions in percentage by weight: 1-60 percent of calcium phosphate; 0-0.2 percent of silicon; 0-0.5 percent of strontium; 0-0.5 percent of zinc; 0-1.0 percent of selenium; 0-1.0 percent of magnesium; 50-95 percent of pulp; and 0.01-5 percent of water, wherein the contents of at least two trace elements cannot be 0 simultaneously. The method for preparing the decoction comprises the following steps of mixing, crushing, squeezing and filtering fruits and nuts, drying pulps, preparing aqueous solution according to main ion compositions of human tissue liquid, adding fruit juice and soluble salt containing the strontium, the zinc, the selenium and the silicon, aging and dissolving out particles, mixing and forming particles and pulps. The invention is simple and convenient in preparation process, the prepared instant traditional decoration is convenient to store and transport and has the characteristics of collaboratively supplying calcium, trace elements and organic nutrient substances, the bioactivity nutrition proportion and the human absorption rate are easy to regulate, excessive acid substances in fresh fruit juice are not related to, the multidimensional nutrition instant traditional decoction can be used as a human health-care drink to regulate the growth of organs, improve bone metabolism and prevent occurrence of diseases caused by nutrition deficiency.
Description
Technical field
The present invention relates to a kind of is Instant Drinks sheet and preparation method thereof, especially improve containing various trace elements and organic nutrient substance tool that organism is grown, regulated skeletal metabolism, what prevent various chronic diseases is Instant Drinks sheet and preparation method thereof, belongs to human nutrition health care drink field.
Background technology
Along with the increase of various chronic diseases (as cardiovascular disease, osteoporosis etc.), the impact of people's pay attention to day by day meals on health.It is predicted, cardiovascular disease more than 50% (Goldberg I. 1994. Functional Foods:Designer Foodss relevant to meals, Pharmafoods, Nutraceuticals. New York:Chapman and Hall, p. 1 – 16.).Of short and small stature, the underweight caused because of malnutrition, skeletal development retardation etc. from the child to young process, have a delicate constitution easily ill etc.The angiocardiopathy that the elderly is more and more multiple, osteoporosis causes the osteoporotic bone injury, is public health problem the most general in world wide.Therefore, all need constantly to strengthen nutrient balance from the baby to the advanced in years old man and supplement.The pathological manifestations of skeletal diseases is summed up as due to calcium deficiency usually, and worldwide, osteoporosis has seriously perplexed middle-aged and old healthy livings.What gone on the market at present take the promotion skeleton development that " replenishing the calcium " be core, the health products numerous and complicated of adjusting skeletal metabolism.The raw materials such as the animal skeleton inorganic calcium phosphate mineral matter that has drawn from, pearl and shell calcium carbonate mineral matter that commercially available calcium-supplementing nutritive preparation has; What have is the chemical synthesis nutritional preparation, as calcium malate, calcium lactate, calcium gluconae, calcium citrate etc.; What have is the collaborative nutriment of binary, as ascorbic deep processing product l threonic acid etc.But these nutrients calcium absorptivities low (bioavilability 30% left and right), especially lack the comprehensively regulating to body, and the risk that exists other nutrient metabolisms to lack of proper care.A up-to-date report demonstration, taking the medicine of replenishing the calcium can increase the risk that the elderly suffers from a heart complaint, and by diet, replenishes the calcium without this misgivings are arranged; Take the people of the medicine of replenishing the calcium, the risk suffered from a heart complaint than user not exceed 30% (Bolland M.J. etc.,
bMJ, 2010,341, c3691).In the prior art, comprise liquid beverage, colloidal state preparation, powder Instant Drinks goods etc.The health food of the disclosed tricalcium phosphate of Chinese patent CN101091720A, resvertrol and cholecalciferol composition, tricalcium phosphate generation to releasing osteoporosis as main calcium tonic that using artificial is synthetic.The Chinese patent CN1086917C that Japanese scholars is declared adds bone mineral, tricalcium phosphate or hydroxyapatite in chewing gum, wishes to reach the dual purpose of tooth-whitening and supplement calcium.In the Chinese patent CN101208017A that Coca-Cola declares, disclose take tricalcium phosphate, one-lime phosphate and calcium lactate as calcium tonic for calcium-replenishing fruit drink of fruit juice additive balance sugar and acidity etc., all attempt to adopt artificial synthetic synthos as calcium tonic, increase the human calcium and absorb channel.The demonstration of " but WomanHealth action plan " report on Epidemiological, menopausal women supplements calcium and vitamin D does not only significantly reduce Hip Fracture, contrary 17% kidney stone dangerous (Jackson RD, the et al. that also increased
n Engl J Med 2006; 354:669.), also there is certain risk in the drink that shows thus to replenish the calcium merely.
The correlative study of epidemiology and nutrition is also found, unbalanced or the long-term lacking of the nutriments such as the mineral matter of human body internal cause picked-up, trace element, amino acid, vitamin, sugar, all can cause various metabolic diseases, people need to pay attention to collaborative the supplementing of multivitamin nutrient material beyond meals more.Be rich in the required amino acid of the metabolism of various human soma and physiological function, vitamin etc. in fruit, especially abundant antioxidant produces the well-tuned effect to regulating the crowd that fat intake is many, antioxidant has the cell ageing of alleviation process, can also prevent that various cancers from occurring, and contribute to prevent the effect such as heart disease.Epidemiological study the analysis showed that possibility that children do not like taking in the meals constipation such as fruit increase by 13 times (Chan M.F. etc.
j Clin Nursing.2010,19,3390); Studies show that the elderly takes in significant quantities of fat and can reduce the life-span, and reduce fat intake, help longevity (Keipert S. etc. most
ageing Cell.2010, DOI:10.1111/j.1474-9726.2010. 00648.x).Up-to-date studies show that, in orange, the specific combination of various antioxidants is taken separately better effects if than various antioxidants, thereby the effect of eating the fruit replenishing vitamins is definitely than taking separately much better than (the Freeman B.L. etc. of some vitamin tablet
j. Food Chem.2010,75, C570).In recent years, along with living standard improves, people also increase the intake of fruit thereupon, and fresh fruit and fruit juice product have enriched people's drink structure, but have acidic materials in fresh fruit and fruit juice, the long-term drinking fruit juice product not only all impacts oral cavity, bone etc.; The most key mid-aged population is poor to this class acidity and ice-cold mouthfeel drink acceptance, to mid-aged population promotion fruit or fruit juice and so on meal supplement, has limitation.In recent years, people also more and more emphasize and pay attention to adding fruit juice as the meals supplement to the baby of lactation, wish and be beneficial to the infantile health growth, but these acid drinks are grown and are produced harmful effect baby's deciduous teeth.
In addition, it is found that the more necessary trace minerals of body metabolism, as strontium can be regulated calcium concentration and bone metabolism in bone, zinc can increase alkaline phosphatase activities and improve DNA content, improves bone strength, silicon and strontium be the balance the body skeletal metabolism significantly, improve bmd, in osteoporosis, show very good therapeutic efficiency (Meunier P.J. etc. aspect preventing and treating
n Engl J Med2006; 350:459; McNaughton S.A. etc.,
brit J Nutr. 2005,94,813; Jugdaohsingh R.
j Bone Miner Res. 2004,19,297; Tournis S.
n. Y. Acad. Sci. 2006,1092,403); Containing the medicine Strontium Ranelate of the Prevention and Treatment of Osteoporosis of strontium in clinical acquisition certain curative effect.In bone defect repair field, also show that silicon, strontium, magnesium, zinc, selenium and other trace elements are impregnated in after calcium phosphate biologically active, biological degradability and the bone defect repair effect that can improve material.Therefore, silicon, strontium, zinc, selenium and other trace elements have been brought into play irreplaceable biological effect in regulating organism metabolism, skeleton development.Also all there are the similar problems such as the bone strength effect is indefinite improved in other with the Chinese herbal medicine beverage that improves spleen and stomach function.The health beverages that the ease of solubility trace element inorganic salts of take in a large amount of prior aries are the raw material development, as sodium selenite, zinc sulfate, zinc sulfate, ferrous sulfate, copper sulphate etc., although can reach fast the higher concentration level after picked-up, but because it is large to control the poor active material loss ratio that causes of release property, absorptivity is low, the drawbacks such as peak valley concentration is obvious, and mechanical mixture causes some micro substance that anti-phenomenon short of money occurs on the one hand, cause serious side reaction, perhaps a certain trace element in a short time high dose cause other active ion metabolism disorder, produce serious counter productive.
The specific biological effect of various micronutrients in balance and balance the body tissue metabolism queried without holding, but the correlative study result also confirms that there is remarkable dose-dependence in adjusting to single micronutrient to metabolism of bone tissue, and the micronutrient that discharges too high dose can cause cytotoxicity or cause other ion metabolism disorder; Lack these micronutrients and will cause the tissue even serious disease that distorts.Human body is comprised of protein, inorganic matter, other carbohydrate, and especially bone tissue is that on nanoscale, self assembly forms has superior mechanical property organic-inorganic composition with the biomolecule such as albumen, polysaccharide and calcium phosphate mineral.The inorganic calcium phosphate mineral are to form with the non-complete crystalline hydroxy apatite containing sodium, potassium and various trace elements, and Trace Elements is being regulated osteoblast activity, promoted young bone development and stabilizing bone eubolism, regulation and control inorganic mineral to bring into play irreplaceable effect in absorbing.But the collaborative compound approach of fruit, calcium mineral matter and other inorganic micronutrients that derives from is not yet arranged at present, thereby avoid directly drinking the harm that fresh fruit, fruit juice cause, and reach and regulate organism metabolism, improve skeletal metabolism, reach the purpose of the chronic diseases such as prevention of osteoporosis disease, cardiovascular disease.Therefore, in the urgent need to Exploration and application trace element and fruit nutrition is plain and with calcium mineral matter organic composite, reach the drink with function of Synergistic, for person in middle and old age, infant crowd improve the human body organism metabolism, prevent that various nutritional deficiency diseases occur, balanced nutritious etc. optimum efficiency.
Summary of the invention
The purpose of this invention is to provide and can obviously improve body metabolism and control various nutritional deficiency diseases pathogenetic multivitamin nutrient is Instant Drinks sheet and preparation method thereof.
Multivitamin nutrient of the present invention is that the Instant Drinks sheet is the powder that contains following component, and the mass percent content of each component is:
Calcium phosphate 1 ~ 60%;
Moisture 0.01 ~ 5%;
The said components sum is 100%, and wherein, silicon, strontium, at least two kinds of materials of zinc and selenium are 0 when different, and said pulp is a kind of or mixture in fruit and nut.
Above-mentioned calcium phosphate is one or more mixtures in unformed calcium phosphate, whitlockite and hydroxyapatite.
Multivitamin nutrient is that the face shaping of Instant Drinks sheet does not exist strict restriction, is generally cylindrical, square or polygonal tablet.
Multivitamin nutrient is the preparation method of Instant Drinks sheet, comprises the following steps:
1) by the fruit that cleans up or/and nut peeling or stoning mix and pulverize, squeeze, filter, obtain pulp and fruit juice, the pulp drying is anhydrated minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 ~ 5.0 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 ~ 2 m м; Cl
?, 163 m м and HCO
3 ?, 4 ~ 27 m м; The pH value of solution is 6 ~ 8.Under stirring condition, in above-mentioned solution, add containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 0 ~ 10:100, Se:P mol ratio are that 0 ~ 10:100, Zn:Ca mol ratio are that 0 ~ 0.8:100 and Sr:Ca mol ratio are 0 ~ 8:100, and SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+at least two kinds of ions are 0 when different.Again to adding step 1 by overall solution volume amount 1 ~ 10% in above-mentioned solution) fruit juice, stir;
3) by step 2) mixed solution for preparing is 35 ~ 180
ounder C, ageing is 0.5 ~ 24 hour, filters, and drying, obtain the powder containing the collaborative doping phosphoric acid calcium of more trace elements, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) drying for preparing pulp in mass ratio 0.2 ~ 3:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
For the Instant Drinks sheet can be dissolved in drinking water fast, can before the step 4) mould molding, in the mixture of powder and pulp, add effervescent agent, the consumption of effervescent agent is 0.05%～1% of powder and pulp mixture weight.
In the present invention, all there is not strict kind restriction in the inorganic salts that doped silicon, zinc, strontium and/or selenium are used, generally containing SiO
3 2-, SeO
4 2inorganic salts are Na
2siO
3, Na
2seO
4; Said containing Sr
2+inorganic salts can be SrCl
2, Sr (NO
3)
2and Sr (CH
3cOO)
2in one or more mixtures.Said containing Zn
2+inorganic salts can be ZnCl
2, Zn (NO
3)
2, Zn (CH
3cOO)
2and ZnSO
4in one or more mixtures.The reagent purity that uses all is not less than its AR purity index.
Above-mentioned fruit and nut can be apples, mandarin orange, grape, strawberry, pears, peach, apricot, Lee, jujube, Kiwi berry, pomegranate, banana, persimmon, longan, gingko, red bayberry, pineapple, lichee, olive, loquat, watermelon, muskmelon, pawpaw, cherry, mulberries, longan, "Hami" melon, sugarcane, orange, coconut, mango, lemon, persimmon, durian, orange, muskmelon, lichee, orange, prune, coconut, mulberries, blueberry, mangosteen, guava, kumquat, dragon fruit, nectarine, panax ginseng fruit, Chinese chestnut, cherry tomato, wax-apple, carambola, fig, olive, cashew nut, chestnut, ginkgo, Chinese torreya, Chinese chestnut, walnut, almond, hawthorn, chain, lily, the hat fruit, muskmelon, pine nut etc.
In preparation process of the present invention, by change, contain SiO
3 2-, SeO
4 2, Zn
2+, and Sr
2+the addition of inorganic salt solution, fruit juice and digestion time, can regulate the particle diameter of calcium phosphate powder and the content of strontium, zinc, silicon and selenium.
Beneficial effect of the present invention is:
Multivitamin nutrient of the present invention is that the Instant Drinks sheet is the compound containing the collaborative doping phosphoric acid calcium particulate of various trace elements and fruit, the organic micronutrient of nut, inorganic calcium phosphate particulate self aggregation forms family of the loose group of high-ratio surface particle, organic nutrient substance molecule in fruit juice can be regulated crystallinity and the form of particulate, and this particulate is conducive to gastrointestinal absorption with the tablet thing of fruit powder produced with combination.Secondly, in synthos, calcium, phosphorus atoms position trace element strontium, zinc, magnesium, silicon, the plasma selenium essential by Human Physiology substitute, nucleation and the particulate stage crystallization degree of growing up is controlled by the organic molecule in fruit juice, thereby be conducive to regulate more trace elements compositely proportional and rate of release thereof by the crystallization control degree, calcium phosphate is unformed or the mineral of partially crystallizable, in stomach, weak acid environment can dissolve gradually, trace quantity mineral substance element also Sustainable Control discharges, and improves the concertedness absorptivity of trace element and calcium, phosphorus; Again, multivitamin nutrient is that the Instant Drinks sheet is compound with pulp and particulate, acidic materials in fruit are excluded, tablet is rendered in drinking water the formation functional beverage is occurred to disintegrate, mouthfeel is good, contribute to infant and the elderly's acceptance and oral, to optimizing diet structure and improving the healthy good action of bringing into play; Trace element is at unformed or partially crystallized calcium phosphate impurity, the rate of release of trace element is controlled by the rate of dissolution of calcium phosphate, can guarantee the characteristic that explosion type that continue, non-discharges, thereby avoid directly taking the various side effects that bring containing micro-solvable inorganic salts.In addition, the technique the present invention relates to is simple, and total calcic rate, micronutrient ratio are easily controlled, and the micronutrient rate of release is easy to the characteristics such as regulation and control, has collaborative distinguishing feature of supplementing lot of trace mineral matter and multiple organic nutrient.
Multivitamin nutrient of the present invention is that the Instant Drinks sheet has excellent biological safety, biologically active and lasting absorbability, can directly render in drinking-water and take, performance is regulated organism metabolism, strengthens bone strength, is regulated the state of mind, prevents various nutritional deficiency diseases to occur.
The accompanying drawing explanation
Fig. 1 is the collaborative doping phosphoric acid calcium particulate X ray diffracting spectrum of various trace elements, in figure, (a) is for containing Kiwi berry, the organic micronutrient of coconut and haw juice, Mg, Zn, Sr, Si and Se trace element, ageing 2 hours, (b) for containing walnut and the organic micronutrient of orange juice, Mg, Sr and Si trace element, ageing 12 hours, (c) for containing pineapple and the organic micronutrient of jujube juice, Mg, Zn, Sr and Si trace element, ageing 18 hours, (d) for containing apple, cashew nut, the organic micronutrient of almond and fig, Mg, Zn, Sr and Si trace element, ageing 0.5 hour.
The specific embodiment
Further illustrate content of the present invention below in conjunction with example, but these examples do not limit the scope of the invention, the medicine materical crude slice of all technology realized based on foregoing of the present invention and preparation all belongs to protection scope of the present invention.
Embodiment 1
1) walnut and the orange that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.4.Under stirring condition, in above-mentioned solution, add containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 8:100, Se:P mol ratio are that 8:100, Zn:Ca mol ratio are that 0.8:100 and Sr:Ca mol ratio are 8:100.Again to adding step 1 by overall solution volume amount 2% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 60
oc, ageing 2 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate, and its X-ray diffracting spectrum is as shown in Fig. 1 (a); As seen from the figure, this calcium phosphate is mainly the compound of whitlockite and hydroxyapatite;
4) by step 3) powder and the step 1 that prepare) drying for preparing mixing pulp in mass ratio 0.2:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
Embodiment 2
1) Kiwi berry, coconut and the hawthorn that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 2 m м; Cl
?, 163 m м and HCO
3 ?, 27 m м; The pH value of solution is 6.5.Under stirring condition, in above-mentioned solution, add containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 4:100, Se:P mol ratio are that 4:100, Zn:Ca mol ratio are that 0.4:100 and Sr:Ca mol ratio are 4:100.Again to adding step 1 by overall solution volume amount 5% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 80
oc, ageing 12 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate, and its X-ray diffracting spectrum is as shown in Fig. 1 (b); As seen from the figure, this calcium phosphate is mainly hydroxyapatite;
4) by step 3) powder and the step 1 that prepare) the mixing pulp for preparing in mass ratio 1:1 mix, add effervescent agent, the consumption of effervescent agent is 0.1% of powder and pulp mixture weight.Use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets again.
Embodiment 3
1) pineapple and the red date that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 3.25 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1.25 m м; Cl
?, 163 m м and HCO
3 ?, 6 m м; The pH value of solution is 7.2.Under stirring condition, in above-mentioned solution, add containing SiO
3 2-, SeO
4 2and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 8:100, Se:P mol ratio are that 4:100 and Sr:Ca mol ratio are 4:100.Again to adding step 1 by overall solution volume amount 6% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 75
oc, ageing 4 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate, and its X-ray diffracting spectrum is as shown in Fig. 1 (c); As seen from the figure, this calcium phosphate is mainly the compound of whitlockite and hydroxyapatite;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 3:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
Embodiment 4
1) apple, cashew nut, almond and the fig that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.2.Under stirring condition, in above-mentioned solution, add containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 2:100, Se:P mol ratio are that 2:100, Zn:Ca mol ratio are that 0.4:100 and Sr:Ca mol ratio are 8:100.Again to adding step 1 by overall solution volume amount 10% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 180
oc, ageing 0.5 hour, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate, and its X-ray diffracting spectrum is as shown in Fig. 1 (d); As seen from the figure, this calcium phosphate is mainly hydroxyapatite;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 0.8:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
Embodiment 5 ~ 9
To microelement concentration and fruit juice ratio, calcium phosphate synthesis temperature and digestion time in the fruit of embodiment 4 and nut compatibility, manual simulation's physiological solution by being adjusted shown in table 1, other condition is with embodiment 4, and also can prepare a series of multivitamin nutrients is the Instant Drinks sheets.
table 1
Claims (11)
1. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) walnut and the orange that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.4, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 8:100, Se:P mol ratio are that 8:100, Zn:Ca mol ratio are that 0.8:100 and Sr:Ca mol ratio are 8:100, again to adding step 1 by overall solution volume amount 2% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 60
oC, ageing 2 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) drying for preparing mixing pulp in mass ratio 0.2:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
2. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) Kiwi berry, coconut and the hawthorn that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 2 m м; Cl
?, 163 m м and HCO
3 ?, 27 m м; The pH value of solution is 6.5, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 4:100, Se:P mol ratio are that 4:100, Zn:Ca mol ratio are that 0.4:100 and Sr:Ca mol ratio are 4:100, again to adding step 1 by overall solution volume amount 5% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 80
oC, ageing 12 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing pulp for preparing in mass ratio 1:1 mix, add effervescent agent, the consumption of effervescent agent is 0.1% of powder and pulp mixture weight, then uses the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
3. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) pineapple and the red date that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 3.25 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1.25 m м; Cl
?, 163 m м and HCO
3 ?, 6 m м; The pH value of solution is 7.2, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, SeO
4 2and Sr
2+inorganic salt solution, and to control Si:P mol ratio in solution be that 8:100, Se:P mol ratio are that 4:100 and Sr:Ca mol ratio are 4:100, then add step 1 by overall solution volume amount 6% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 75
oC, ageing 4 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 3:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
4. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) apple, cashew nut, almond and the fig that clean up are removed the peel respectively, stoning, mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.2, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, SeO
4 2, Zn
2+and Sr
2+inorganic salt solution, and in control solution, the Si:P mol ratio is that 2:100, Se:P mol ratio are that 2:100, Zn:Ca mol ratio are that 0.4:100 and Sr:Ca mol ratio are 8:100, again to adding step 1 by overall solution volume amount 10% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 180
oC, ageing 0.5 hour, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, selenium, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 0.8:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
5. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) by the peeling of the "Hami" melon that cleans up and stoning, the cashew nut peeling, then both mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.2, under stirring condition, in above-mentioned solution, adds containing Zn
2+and Sr
2+inorganic salt solution, and to control Zn:Ca mol ratio in solution be that 0.3:100 and Sr:Ca mol ratio are 5:100, then add step 1 by overall solution volume amount 3% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 65
oC, ageing 20 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, magnesium, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 0.8:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
6. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) fig, pomegranate and the mango that clean up are removed the peel respectively, stoning, then the three mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.2, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, Zn
2+and Sr
2+inorganic salt solution, and to control Si:P mol ratio in solution be that 2:100, Zn:Ca mol ratio are that 0.5:100 and Sr:Ca mol ratio are 8:100, then add step 1 by overall solution volume amount 5% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 75
oC, ageing 15 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 0.8:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
7. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) coconut, muskmelon, Chinese chestnut and the prune that clean up are removed the peel respectively, stoning, then four mix, pulverize, squeezing and filtering, to the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.2, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, Zn
2+and Sr
2+inorganic salt solution, and to control Si:P mol ratio in solution be that 3:100, Zn:Ca mol ratio are that 0.4:100 and Sr:Ca mol ratio are 6:100, then add step 1 by overall solution volume amount 8% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 105
oc, ageing 3 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 0.8:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
8. the preparation method that multivitamin nutrient is the Instant Drinks sheet is characterized in that comprising the following steps:
1) mango and the longan that clean up are removed the peel respectively, stoning, then both mix, pulverize, squeezing and filtering, obtain the pulp and the fruit juice that mix, will mix the pulp drying and anhydrate minute;
2) manually prepare simulated body fluid by main inorganic ion concentration in human plasma, in solution, the concentration of each inorganic ions is respectively Na
+, 142 m м; K
+, 5 m м; Ca
2+, 2.5 m м; Mg
2+, 1.5 m м; SO
4 2, 1 m м; HPO
4 2, 1 m м; Cl
?, 163 m м and HCO
3 ?, 4 m м; The pH value of solution is 7.2, under stirring condition, in above-mentioned solution, adds containing SiO
3 2-, Zn
2+and Sr
2+inorganic salt solution, and to control Si:P mol ratio in solution be that 6:100, Zn:Ca mol ratio are that 0.3:100 and Sr:Ca mol ratio are 8:100, then add step 1 by overall solution volume amount 10% in above-mentioned solution) blended fruit juice, stir;
3) by step 2) mixed solution for preparing is warmed up to 120
oC, ageing 10 hours, filter, and drying obtains the calcium phosphate powder containing the collaborative doping of strontium, zinc, magnesium, silicon, vitamin, amino acid and carbohydrate;
4) by step 3) powder and the step 1 that prepare) the mixing fruit powder for preparing in mass ratio 0.8:1 mix, then use the compression mold moulding, obtaining multivitamin nutrient is the Instant Drinks sheets.
9. the preparation method who is the Instant Drinks sheet according to the arbitrary described multivitamin nutrient of claim 1-8, is characterized in that, said containing SiO
3 2-and SeO
4 2inorganic salts be respectively Na
2siO
3and Na
2seO
4.
10. the preparation method who is the Instant Drinks sheet according to the arbitrary described multivitamin nutrient of claim 1-8, is characterized in that said containing Sr
2+inorganic salts are SrCl
2, Sr (NO
3)
2and Sr (CH
3cOO)
2in one or more mixtures.
11. the preparation method who is the Instant Drinks sheet according to the arbitrary described multivitamin nutrient of claim 1-8, is characterized in that said containing Zn
2+inorganic salts are ZnCl
2, Zn (NO
3)
2, Zn (CH
3cOO)
2and ZnSO
4in one or more mixtures.
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| CN103040068A (en) * | 2012-12-21 | 2013-04-17 | 北京航洋健康科技有限公司 | Pomegranate solid beverage and preparation method thereof |
| CN103202474A (en) * | 2013-04-27 | 2013-07-17 | 刘春雷 | Longan and walnut dew (juice) |
| CN103461999A (en) * | 2013-08-13 | 2013-12-25 | 娄志 | Processing method for nutritious and health care fruit-vegetable powder rich in vitamins |
| CN109418809A (en) * | 2017-08-26 | 2019-03-05 | 石家庄以岭药业股份有限公司 | A kind of prune chewable tablets and preparation method thereof |
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| DE202006012450U1 (en) * | 2005-08-30 | 2006-10-26 | Esarom Essenzenfabrik Ges.M.B.H. | Beverage raw material, useful for preparing e.g. lemonade, comprises flavoring materials, drinking agent, sweetening agent, auxiliary materials, juices and optionally contains e.g. sodium hydrogencarbonate |
| CN101664189A (en) * | 2009-09-24 | 2010-03-10 | 浙江大学 | Multielement nutrition compound and preparing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE202006012450U1 (en) * | 2005-08-30 | 2006-10-26 | Esarom Essenzenfabrik Ges.M.B.H. | Beverage raw material, useful for preparing e.g. lemonade, comprises flavoring materials, drinking agent, sweetening agent, auxiliary materials, juices and optionally contains e.g. sodium hydrogencarbonate |
| CN101664189A (en) * | 2009-09-24 | 2010-03-10 | 浙江大学 | Multielement nutrition compound and preparing method thereof |
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