CN103070338B - Blueberry chewable tablet - Google Patents

Blueberry chewable tablet Download PDF

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Publication number
CN103070338B
CN103070338B CN2013100583725A CN201310058372A CN103070338B CN 103070338 B CN103070338 B CN 103070338B CN 2013100583725 A CN2013100583725 A CN 2013100583725A CN 201310058372 A CN201310058372 A CN 201310058372A CN 103070338 B CN103070338 B CN 103070338B
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blue berry
chewable tablet
blueberry
granulate
formula
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CN103070338A (en
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林继华
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Liaoning Qianliming Pharmaceutical (Group) Co., Ltd.
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LIAONING QIANLIMING PHARMACEUTICAL (GROUP) CO Ltd
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Abstract

The invention relates to a blueberry chewable tablet with a healthcare function, and the chewable tablet comprises the following ingredients: blueberry extraction powder, crystal sugar, citric acid, maltodextrin, soluble dietary fibers, flavoring orange essence and magnesium stearate. The blueberry chewable tablet is produced through the production process such as pulverizing, mixing, pelleting, drying and pressing.

Description

A kind of blue berry chewable tablet
Technical field
The present invention relates to a kind of compositions with health care, particularly a kind ofly contain the blue berry extract powder and added the compositions such as citric acid, maltodextrin, through the production technologies such as pulverizing, mixing, pelletize, oven dry, compacting, the chewable tablet of making.
Background technology
Blue berry (Blueberry), the Latin formal name used at school: Semen Trigonellae means the meaning of blue berry.It is blue that a kind of little berry, fruit are, and color and luster is beautiful, pleasing, blue and wrapped up by 1 layer of white really powder, the sarcocarp exquisiteness, and seed is minimum.Sweet and sour palatability, and have fragrant refreshing pleasant fragrance, for eating good merchantable brand raw.
In Blueberry, except conventional sugar, acid and Vc, be rich in VE, VA, VB, SOD, arbutin, protein, anthocyanin, edible fiber and abundant K, Fe, the mineral elements such as Zn, Ca.Blueberry belongs to the nourishing healthy fruit of homoamino acid, high zinc, high calcium, high ferro, high-copper, homovitamin.It not only has good nutrition health-care functions, also has the functions such as the cranial nerve of preventing is aging, heart tonifying, anticancer vessel softening, enhancing human organism immunity.
Blueberry contains abundant nutritional labeling, belongs to the nourishing healthy fruit of homoamino acid, high zinc, high calcium, high ferro, high-copper, homovitamin.It not only has good nutrition health-care functions, also have prevent that cranial nerve is aging, heart tonifying, anticancer, vessel softening, enhancing people's the functions such as human body immunity, its nutritive value is far above fruit such as Fructus Mali pumilae, Fructus Vitis viniferae, Fructus Citri tangerinaes, can be rated as " king of world's fruit ". but because the blue berry fancy price, it is far away as welcome as Fructus Mali pumilae, Fructus Citri junoris at present.
The effect of blue berry and effect
(1) quick-acting protection eyes, fabulous function of improving eyesight, be called as the treasured of eye protection.Along with the age increases; in eyes, erythropsin is decomposed; and the VMA in Blueberry (anthocyani pigment) can protect the blood capillary of eyes; improve blood circulation; promote the erythropsin resynthesis; can improve vision, widen the vision, alleviate eyestrain, strengthen night vision, prevention, long-term taking can keep vision lasting.
(2) in and free radical, antioxidation, strengthen body immunity.Free radical can directly cause 100 various diseases, comprises various cancers, cardiovascular and cerebrovascular vessel, arteriosclerosis, diabetes etc.Vaccinium oxycoccus pigment content is the abundantest; the special molecular structure of anthocyanidin; can make free radical become stable; can not form the dangerous substance that can cause chain reaction again; also can form the anti-oxidation protection film with collagen protein; Cell protection and organizing not by free-radical oxidation, help VC, VE to absorb, and strengthens antioxidation.
(3) delay the cranial nerve aging, memory reinforcing, prevention senile dementia.The blue berry compound can promote the growth of memory reflection district brain cell, improve impermanent memory, improve cognitive ability, pass through blood brain barrier, improve the degeneration senile dementia, delay and transform senile symptom, treatment parkinson disease and Alzheimer degenerative brain disorder, have rejuvenescent magical effect.
(4) reduce cholesterol, protection blood vessel, cardiac function enhancing.The compound that can resist fungal infection is arranged in blue berry, can reduce body's cholesterol, prevention of obesity, strengthen VAR, reduce capillary fragility, keep blood vessel penetrating, strengthen the function of blood capillary, vein, tremulous pulse, promote blood circulation, strengthen skin elasticity, improve varicosis and edema, suppress platelet and solidify, formation and the arteriosclerosis of pre-preventing thrombosis, reduce the cardiovascular disease incidence rate.
(5) eliminate inflammation in body, have the effect of anticancer.Flavonoid isoreactivity compound in blue berry, can kill food-borne causal agent, strengthen useful growth of lactobacillus, especially to urinary tract infection, chronic nephritis, leukemia, non-bacterial inflammation such as arthritis etc. have the preventive and therapeutic effect shown the most, can strengthen the function of joint and soft tissue, Blueberry contains cancer-resisting substance such as selenium etc., and the enzymatic activity that cancerous cell is bred rapidly is suppressed.Can prevent and treat hepatocarcinoma, uterus carcinoma, carcinoma of prostate, breast carcinoma etc.
(6) prevent and treat the other diseases that diabetes and diabetes cause.Phytoalexin in blue berry " pterostibene ", be free from side effects except cholesterol reducing, can also regulate blood glucose, prevents and treats type Ⅱdiabetes mellitus, can reduce the initiation potential of diabetes, the generation of complication.
The effect blue berry contains cyanine two pigments, has activation retina effect, can strengthen vision, prevents eyeball fatigue;
Blue berry is rich in vitamin C, and cardiac function enhancing is arranged, and prophylaxis of cancer and cardiopathic effect can prevent that cranial nerve is old and feeble, it is mental to promote;
The effect target that blue berry is pursued except the intrinsic antioxidation of anthocyanidin, anti-aging, improve immunity function, more lay particular emphasis on the increase alleviating asthenopia, eliminate the ophthalmic free radical, promote rhodopsin to generate, the effect of antagonism pseudomyopia.
Blue berry is a kind ofly to have antioxidation, improve ciliary spasm, promotes rhodopsin to generate, and improves scotopia, eliminates the ophthalmic free radical, antagonism pseudomyopia and asthenopia effect.It is contained to human body beneficiating ingredient anthocyanidin, takes generation and reparation that this product can resist pseudomyopia.For reducing the adolescent myopia rate, improve vision, improve teen-age eye health and played positive effect.Take the vision subhealth state of this product for the adult, as asthenopia, eye is dry, eye is puckery, visual deterioration etc.; Old people's presbyopia and the prevention of ocular disease, have good help and improvement effect, for people's eye care provides more more options, for people's eye is healthy, erects firm defence line.
At present, blue berry goods aspect, most of with effervescent tablet, buccal tablet, liquid beverage form both at home and abroad, add in addition in other food.Be necessary to provide oral form that blue berry is new to adapt to adolescent myopia crowd's needs.
Summary of the invention
The inventor is through research, develop a kind of, good mouthfeel, color and luster is stable, the blue berry chewable tablet of just melt in the mouth.Blue berry chewable tablet of the present invention, according to percentage by weight, its formula is composed as follows:
Blue berry extract powder 2%
White sugar 70%
Citric acid 3%
Maltodextrin 7%
Water soluble dietary fiber 15%
Flavoring orange essence 2%,
Magnesium stearate 1%
Raw material in above formula all can be bought and obtain on market.As: the multiple logical soluble dietary fiber powder of trade name unit, the blue berry extract powder that the safe imperial biochemical technology company limited in Shaanxi Si Nuote Bioisystech Co., Ltd and Guangzhou is produced, blue berry extract powder of the present invention, also can be according to prior art from Blueberry, extracting and obtain, described blue berry extract powder, preferred anthocyanidin content wherein is 10%-40%, as the blue berry extract powder of east, Huizhou plant health Science and Technology Ltd. production.
Blue berry chewable tablet of the present invention, its preparation method is as follows:
1. weighing, get raw material after crushed, accurately takes various dry powder raw materials by each formula proportion;
2, be dry mixed, mixing of materials is even;
3, wet mixing, add water by the material after being dry mixed and carry out wet mixing;
4, granulate;
5, drying, by particle drying;
6, granulate;
7, tabletting.
Described preparation method belongs to the routine techniques for preparing tablet, only need prepare and get final product according to a conventional method.
Blue berry formula of chewable tablets of the present invention, obtain through screening, and screening process is as follows:
Sample of the present invention and the control sample in the embodiment of the present invention used in experiment, wherein the mouthfeel experiment adopts 10 people to taste the marking mode, full marks are 100 minutes, comprehensive 10 people's scorings, color and luster adopts 40 ℃ of degree of temperature, and humidity 70 incubators were placed 30 days, observes color and luster and changes, dissolution velocity adopts sample to be placed in 20 ℃ of water and stirs, to all dissolving the required time.
Figure 3
Blue berry chewable tablet of the present invention be take blue berry powder and is raw material, add white sugar, food additive (citric acid, maltodextrin) Fructus Vitis viniferae powdered flavor magnesium stearate, the directly edible blue berry chewable tablet of making through certain technique such as pulverizing, mixing, pelletize, drying, compacting, metering, packing.
Blue berry chewable tablet of the present invention has the characteristics such as pure natural, nourishing healthy, meets Present Domestic to consume fashion outward, and be the daily first-selected good merchantable brand of selecting of consumer, product has wide market prospect.
In modern society, TV, the extensive of automobile and computer popularized, the increase of operating pressure and life stress, eyestrain and associated oculopathy get more and more.According to U.S.'s nutritionist suggestion, eat the blue berry product every day, can reach the purpose of eye health.According to the U.S., Japan, the scholar of European Section research, frequent edible blue berry goods, vision enhancing significantly, anti-eye strain.
Blue berry chewable tablet of the present invention is the science compositing formula, is presented as that ecosystem, content are high, three characteristics of mouthfeel.Its technique is special, makes the dosage form that can chew, be conducive to absorb---chewable tablet.Change traditional tablet by the method for making of starch as auxiliary type agent, make this product in taking process, its effective ingredient can be absorbed by the body equably, has greatly improved bioavailability, gives full play to the effective ingredient effect of product, improves effect.
No matter the science of blue berry chewable tablet of the present invention formula, or the advance of technique dosage form, all unique have leading characteristics.Especially at anthocyanidin to aspect people's eye care, this project has had new breakthrough and development.This Project Product market utilizes and has a extensive future.
The technique of blue berry chewable tablet of the present invention and dosage form have had very much progress, have improved bioavailability, and effect is significantly increased.This product could be introduced to the market rapidly, improves market share, is also that the crowds such as compatriots' eye care, especially adolescent myopia provide a kind of health care to select!
By clinical observation, to alleviating asthenopia, improve the successful of vision.
By clinical observation, blue berry chewable tablet tool of the present invention has some improvement, improves vision and strengthens the effect that eyes are looked the aspects such as thing endurance
1,8-18 years old, more than eyesight improving 2 row (standard logarithmic visual acuity chart sighting target), the vision endurance improved 30%;
2, adult, more than eyesight improving 1 row (standard logarithmic visual acuity chart sighting target), the vision endurance improves 20%;
3, the mouthfeel satisfaction reaches 95%;
4, bioavailability improves 32% than like product (as the blue berry chewable tablet of extra large king's production).
Relatively, following many index is all higher than prior art for blue berry chewable tablet of the present invention and similar products at home and abroad:
1, improve vision, strengthen and look the thing endurance;
2, bioavailability;
3, mouthfeel satisfaction;
4, anthocyanidin content.
The research and development success of this project is also put the eye health into compatriots on market, and especially teen-age eye health provides the material support.
The product description of blue berry chewable tablet of the present invention is as follows:
[name of product] common name: Herba Senecionis Scandentis board blue berry chewable tablet [Main Ingredients and Appearance] blue berry extract
[specification] 1g/ grain [shelf-life] [storage procedures] shading in 18 months, sealing, preserve at shady and cool dry place.[points for attention] this product can not replace medicine.[manufacturing enterprise] enterprise name: Liaoning Herba Senecionis Scandentis Pharmaceutical Group Co.,Ltd
The specific embodiment:
Further illustrate by the following examples the present invention, but not as limitation of the present invention.
Embodiment 1, the formula 1 that experiment is adopted
Blue berry extract powder 2g
White sugar 70g
Citric acid 3g
Maltodextrin 7g
Water soluble dietary fiber 15g
Flavoring orange essence 2g
Magnesium stearate 1g
Preparation method is as follows:
Get raw material after crushed, accurately take by formula proportion, mixing of materials is even; Add water-wet; Granulate; Drying, granulate, tabletting.
Below for testing the blue berry formula of chewable tablets that compares use:
The formula 2 that experiment is adopted
Blue berry extract powder 2g
White sugar 70g
Maltodextrin 7g
Water soluble dietary fiber 15g
Apple essence 2g
Calcium stearate 1g
Preparation method is as follows:
Get raw material after crushed, accurately take by formula proportion, mixing of materials is even; Add water-wet; Granulate; Drying, granulate, tabletting.
The formula 3 that experiment is adopted
Blue berry extract powder 2g
White sugar 70g
Tartaric acid 3g
Water soluble dietary fiber 15g
Flavoring pineapple essence 2g
Pulvis Talci 1g
Preparation method is as follows:
Get raw material after crushed, accurately take by formula proportion, mixing of materials is even; Add water-wet; Granulate; Drying, granulate, tabletting.
The formula 4 that experiment is adopted
Blue berry extract powder 2g
White sugar 70g
Lactic acid 3g
Maltodextrin 7g
Flavoring banana essence 2g
Micropowder silica gel 1g
Preparation method is as follows:
Get raw material after crushed, accurately take by formula proportion, mixing of materials is even; Add water-wet; Granulate; Drying, granulate, tabletting.
The formula 5 that experiment is adopted
Blue berry extract powder 2g
White sugar 70g
Potassium citrate 3g
Maltodextrin 7g
Water soluble dietary fiber 15g
Magnesium stearate 1g
Preparation method is as follows:
Get raw material after crushed, accurately take by formula proportion, mixing of materials is even; Add water-wet; Granulate; Drying, granulate, tabletting.

Claims (2)

1. blue berry chewable tablet, its formula is composed as follows:
Blue berry extract powder 2%
White sugar 70%
Citric acid 3%
Maltodextrin 7%
Water soluble dietary fiber 15%
Flavoring orange essence 2%,
Magnesium stearate 1%.
2. the preparation method of the described blue berry chewable tablet of claim 1, is characterized in that, step is as follows: get raw material after crushed, accurately take by formula proportion, mixing of materials is even; Add water-wet; Granulate; Drying, granulate, tabletting.
CN2013100583725A 2013-02-25 2013-02-25 Blueberry chewable tablet Active CN103070338B (en)

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Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494134B (en) * 2013-08-28 2015-06-24 沈阳农业大学 Blueberry lozenge for relieving asthenopia and preparation method thereof
CN104621552A (en) * 2013-11-12 2015-05-20 江苏艾兰得营养品有限公司 Eyesight protecting and improving chewable tablet and preparation method thereof
CN105533316A (en) * 2014-11-04 2016-05-04 威海特伦斯生物工程有限公司 Production method of blueberry chewable tablets for alleviating visual fatigue
CN104366328A (en) * 2014-11-07 2015-02-25 柳城县天地自然食品有限公司 Chewable tablets containing blueberries and poria cocos, and preparation method of chewable tablets
CN104522645A (en) * 2014-12-09 2015-04-22 大兴安岭至臻尚品寒带生物技术有限公司 Formula of blueberry anthocyanin tablets and production process of blueberry anthocyanin tablets
CN104814995A (en) * 2015-05-12 2015-08-05 沈小玲 Oriental blueberry fruit powder health product composition as well as preparation method and application thereof
CN106036626A (en) * 2016-06-16 2016-10-26 湖北工业大学 Mulberry wine lees chewable tablet preparation method
CN106343548B (en) * 2016-08-24 2019-08-02 东北林业大学 A kind of licoflavone composite blueberry juice chewable tablets and preparation method thereof
CN110710673A (en) * 2019-09-26 2020-01-21 南宁海王健康生物科技有限公司 Blueberry compound vitamin C chewable tablet and preparation method thereof
CN110522030A (en) * 2019-10-12 2019-12-03 烟台华康海洋食品有限公司 A kind of sea cucumber nutrient chewable tablets and preparation method thereof

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CN101385769A (en) * 2008-10-24 2009-03-18 上海应用技术学院 Blueberry pearl chewing tablet and preparation method thereof

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Owner name: LIAONING QIANLIMING PHARMACEUTICAL (GROUP) CO., LT

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Address after: 110000 No. 76, unity Road, Shenhe District, Liaoning, Shenyang

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