CN102125619A - Chinese medicinal compound for adjunctively reducing blood sugar - Google Patents
Chinese medicinal compound for adjunctively reducing blood sugar Download PDFInfo
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- CN102125619A CN102125619A CN2010100193294A CN201010019329A CN102125619A CN 102125619 A CN102125619 A CN 102125619A CN 2010100193294 A CN2010100193294 A CN 2010100193294A CN 201010019329 A CN201010019329 A CN 201010019329A CN 102125619 A CN102125619 A CN 102125619A
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Abstract
The invention relates to a Chinese medicinal compound, which is characterized by comprising the following nine traditional Chinese medicines in percentage by weight: 10 to 45 percent of mulberry leaf, 10 to 50 percent of buckwheat, 10 to 50 percent of guava (Chinese white olive), 10 to 45 percent of red lucid ganoderma, 10 to 40 percent of red ginseng, 5 to 40 percent of corsvenor momordica fruit, 5 to 40 percent of cherokee rose fruit, 5 to 40 percent of gardenia and 5 to 40 percent of broadleaf holly leaf. The nine traditional Chinese medicines and extracts thereof in the compound can be prepared into all medical oral preparations such as tea bags, granules, instant medicines, oral liquid, beverages, capsules, tablets, dispersants and the like. The Chinese medicinal compound has the effects of reducing blood sugar, regulating blood sugar, reducing diabetes complications, preventing diabetes and cardiovascular diseases and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine compound, have blood sugar lowering, blood sugar regulation, alleviate diabetic complication, effects such as prevent diabetes, cardiovascular disease.Crude drug in the compound recipe and extract thereof can be made into all oral formulations on medical such as teabag, granule, electuary, oral liquid, beverage and capsule, tablet, dispersant.
Background technology
Along with improving constantly of living standards of the people, various what is called " affluenza " are also threatening human health.Diabetes are a kind of representational lifelong diseases wherein, are characterized in the sickness rate height, and each age level all exists, and the teenager sickness rate also constantly rises.According to authoritative institution's prediction, by 2010, the diabetics of China will reach about 6,000 ten thousand people.China mainly is based on the blood sugar lowering Western medicine at present, and Chinese patent medicine is auxilliary, causes that drug resistance, Drug resistance, lesions of liver and kidney etc. make the patient painful more but take medicine for a long time.There is investigation to show diabetics to cooperating Drug therapy, stablizing blood glucose, urgent to the blood sugar lowering relevant food demand that human body has no side effect.
Show that according to the market survey situation there is inferior quality in blood sugar reducing health product on the market, costs an arm and a leg, take problem such as inconvenience at present.Make tea as Hypoglycemic bag, Folium Mori tea, Radix Et Rhizoma Fagopyri Tatarici tea, Folium Ilicis etc. are arranged, these teabag show that all composition is more single, and mouthfeel, visual effect all are weak, so that poor, the mouthfeel bitterness of hypoglycemic effect, dark brown not person of modern times meaning.In addition, the antihypelipidemic product of these single components only has effects such as blood sugar lowering, fat-reducing, but for diabetic population, they not only need blood sugar regulation, more need to regulate the allomeric function of health, as alleviate diabetic complication to physical impairment, raising immunity etc.The present invention is a kind of Chinese medicine compound, has not only solved problems such as present antihypelipidemic product DeGrain, has obvious blood sugar lowering, blood sugar regulation effect, and the adjuvant therapy of diabetes complication improves effects such as body immunity.
Summary of the invention
The present invention is a kind of Chinese medicine compound, and prescription is made up of Folium Mori, Radix Et Rhizoma Fagopyri Tatarici, Fructus psidii guajavae immaturus (Fructus Canarii), Ganoderma lucidum (Leyss. Ex Fr.) Karst., Radix Ginseng Rubra, Fructus Momordicae, Fructus Rosae Laevigatae, Fructus Gardeniae, Folium Ilicis nine flavor Chinese medicines.Each medical material composition proportioning is in the Chinese medicine compound: Folium Mori 10%-45%, Radix Et Rhizoma Fagopyri Tatarici 10%-50%, Fructus psidii guajavae immaturus (Fructus Canarii) 10%-50%, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 10-45%, Radix Ginseng Rubra 10-40%, Fructus Momordicae 5%-40%, Fructus Rosae Laevigatae 5%-40%, Fructus Gardeniae 5%-40%, Folium Ilicis 5%-40%.Chinese medicine compound not only has obvious blood sugar lowering, blood sugar regulation effect, and can assist treating diabetes, alleviates the complication that treating diabetes produces, effects such as human body immunity improving power.The innovation part of this Chinese medicine compound has following 6 points:
1. Chinese medicine compound is made up of Folium Mori, Radix Et Rhizoma Fagopyri Tatarici, Fructus psidii guajavae immaturus (Fructus Canarii), Ganoderma lucidum (Leyss. Ex Fr.) Karst., Radix Ginseng Rubra, Fructus Momordicae, Fructus Rosae Laevigatae, Fructus Gardeniae, Folium Ilicis, and reasonable compatibility does not have any incompatibility.
In the Chinese medicine compound most of crude drug source in the food materials of medicine-food two-purpose, safe and reliable, without any side effects.
3. all Chinese medicines of Chinese medicine compound all have blood sugar lowering, blood sugar regulation effect.
4. add Ganoderma lucidum (Leyss. Ex Fr.) Karst., Radix Ginseng Rubra in the Chinese medicine compound, have blood sugar lowering simultaneously, regulate blood effect, the effect of human body immunity improving power, strengthening the body resistance.
5. add Fructus Momordicae, the Fructus Rosae Laevigatae of auxiliary hyperglycemic effect in the Chinese medicine compound, both are natural sweeting agents, can be used for the correctives of preparation.
6. add the Fructus Gardeniae of auxiliary hyperglycemic effect in the Chinese medicine compound, can be used for the natural toner in the preparation.
The specific embodiment
1. teabag: take by weighing Folium Mori 200g, Radix Et Rhizoma Fagopyri Tatarici 50g, Fructus psidii guajavae immaturus (Fructus Canarii) 150g, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 50g, Radix Ginseng Rubra 100g, Fructus Momordicae 50g, Fructus Rosae Laevigatae 50g, Fructus Gardeniae 100g, Folium Ilicis 50g nine flavor Chinese medicine crude drugs, pulverize separately is to the 20-40 order, sieve, fully mix, sterilization, teabag is made in pack.
2. granule or electuary: take by weighing Folium Mori 200g, Radix Et Rhizoma Fagopyri Tatarici 50g, Fructus psidii guajavae immaturus (Fructus Canarii) 150g, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 50g, Radix Ginseng Rubra 100g, Fructus Momordicae 50g, Fructus Rosae Laevigatae 50g, Fructus Gardeniae 100g, Folium Ilicis 50g nine flavor Chinese medicine crude drugs, add 8 times of amounts of medical material, 50% ethanol, reflux, extract, 2 hours, filter, medicinal residues add 4 times of amount 50% ethanol again, reflux, extract, 2 hours is filtered, and merges filtrate twice, evaporating solvent must precipitate drying, granulate, sterilization, granule or electuary are made in pack.
3. oral liquid and beverage: take by weighing Folium Mori 200g, Radix Et Rhizoma Fagopyri Tatarici 50g, Fructus psidii guajavae immaturus (Fructus Canarii) 150g, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 50g, Radix Ginseng Rubra 100g, Fructus Momordicae 50g, Fructus Rosae Laevigatae 50g, Fructus Gardeniae 100g, Folium Ilicis 50g nine flavor Chinese medicine crude drugs, add 8 times of amount distilled water of medical material, decocted 2 hours, filter, medicinal residues add 4 times of amount distilled water again, decocted 2 hours, filter, merge filtrate twice, simmer down to (medical material/extracting solution) M/V=1: 5, toning, flavoring, fill, oral liquid, beverage are made in sterilization.
4. capsule: take by weighing Folium Mori 200g, Radix Et Rhizoma Fagopyri Tatarici 50g, Fructus psidii guajavae immaturus (Fructus Canarii) 150g, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 50g, Radix Ginseng Rubra 100g, Fructus Momordicae 50g, Fructus Rosae Laevigatae 50g, Fructus Gardeniae 100g, Folium Ilicis 50g nine flavor Chinese medicine crude drugs, add 8 times of amounts of medical material, 50% ethanol, reflux, extract, 2 hours, filter, medicinal residues add 4 times of amount 50% ethanol again, reflux, extract, 2 hours is filtered, and merges filtrate twice, evaporating solvent must precipitate drying, granulate, sterilization, the capsulae vacuus of packing into is made capsule.
5. tablet: take by weighing Folium Mori 200g, Radix Et Rhizoma Fagopyri Tatarici 50g, Fructus psidii guajavae immaturus (Fructus Canarii) 150g, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 50g, Radix Ginseng Rubra 100g, Fructus Momordicae 50g, Fructus Rosae Laevigatae 50g, Fructus Gardeniae 100g, Folium Ilicis 50g nine flavor Chinese medicine crude drugs, add 8 times of amounts of medical material, 50% ethanol, reflux, extract, 2 hours, filter, medicinal residues add 4 times of amount 50% ethanol again, reflux, extract, 2 hours is filtered, and merges filtrate twice, evaporating solvent must precipitate drying, granulate, sterilization, tabletting is made tablet.
6. dispersant: take by weighing Folium Mori 200g, Radix Et Rhizoma Fagopyri Tatarici 50g, Fructus psidii guajavae immaturus (Fructus Canarii) 150g, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 50g, Radix Ginseng Rubra 100g, Fructus Momordicae 50g, Fructus Rosae Laevigatae 50g, Fructus Gardeniae 100g, Folium Ilicis 50g nine flavor Chinese medicine crude drugs, add 8 times of amounts of medical material, 50% ethanol, reflux, extract, 2 hours, filter, medicinal residues add 4 times of amount 50% ethanol again, reflux, extract, 2 hours, filter, merge filtrate twice, evaporating solvent, precipitation is dry, add and help powder, fully stir, make various dispersants.
7. blood sugar lowering experiment
(1) zoopery
Intact animal's model, zoic model with hyperglycemia, getting Hypoglycemic bag makes tea and adds the water of 10 times of volumes, at 80 ~ 90 ℃ of heating 60min, extract 2 times, merge extractive liquid, also is concentrated to a certain amount of, make basic, normal, high three dosage groups respectively, each concentration is respectively 0.5g/kg, 1g/kg and 3g/kg, and other establishes distilled water blank group and hyperglycemia model group.Normal mouse, hyperglycemia mice give glucose 2.5g/kgbw and irritate stomach after irritating stomach with the continuous 14d of each dosage of teabag respectively, measure blood glucose value mutually respectively in 0, when three of 0.5h and 2.0h.The result shows that Hypoglycemic bag is made tea does not have influence to normal mouse blood sugar, and the hyperglycemia mice is had remarkable hypoglycemic activity.Experimental result sees Table 1, table 2.
Table 1 Hypoglycemic bag is made tea to the influence of the anti-sugar amount of normal mouse
Table 2 Hypoglycemic bag is made tea to the influence of the anti-sugar amount of hyperglycemia mice
(2) human experimentation
Get Hypoglycemic bag and make tea and add the water of 10 times of volumes, at 80～90 ℃ of heating 60min, extract 2 times, merge extractive liquid, also is concentrated to a certain amount ofly, and concentration is 6g/60kg, drinks for three times on the one.In 5 routine non-insulin-depending types (II type) patient's clinical trial, do not share Hypoglycemic bag and make tea preceding clinically with 5tid glipizide (mg), 10tid diabetes pill (grain); Share Hypoglycemic bag and make tea treatment back with 5qd glipizide (mg), 5tid diabetes pill (grain), mensuration patient blood glucose, glucose in urine, the result shows the Hypoglycemic bag auxiliary hyperglycemic effect of making tea.M is a glipizide, and x is a diabetes pill.Patient's blood glucose, glucose in urine the results are shown in Table 1.
Table 1 is used make tea Comparison of therapeutic (n=5) before and after the partner treatment of Hypoglycemic bag
Claims (7)
1. the present invention relates to a kind of Chinese medicine compound, its prescription is characterised in that: be made up of Folium Mori, Radix Et Rhizoma Fagopyri Tatarici, Fructus psidii guajavae immaturus (Fructus Canarii), Ganoderma lucidum (Leyss. Ex Fr.) Karst., Radix Ginseng Rubra, Fructus Momordicae, Fructus Rosae Laevigatae, Folium Ilicis, Fructus Gardeniae nine flavor medical materials.
2. according to each composition proportion of composing in the compound recipe of claim 1: Folium Mori 10%-45%, Radix Et Rhizoma Fagopyri Tatarici 10%-50%, Fructus psidii guajavae immaturus (Fructus Canarii) 10%-50%, Ganoderma lucidum (Leyss. Ex Fr.) Karst. 10-45%, Radix Ginseng Rubra 10-40%, Fructus Momordicae 5%-40%, Fructus Rosae Laevigatae 5%-40%, Fructus Gardeniae 5%-40%, Folium Ilicis 5%-40%.
3. have blood sugar lowering, blood sugar regulation according to claim 1,2 Chinese medicine compound and proportioning, alleviate diabetic complication, effects such as prevent diabetes, cardiovascular disease.
4. make teabag according to claim 1,2,3 Chinese medicine crude drug and extract thereof.
5. make granule or electuary according to claim 1,2,3 Chinese medicine crude drug and extract thereof.
6. make oral liquid and beverage according to claim 1,2,3 Chinese medicine crude drug and extract thereof.
7. make all oral formulations on medical such as capsule, tablet, dispersant according to claim 1,2,3 Chinese medicine crude drug and extract thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2010100193294A CN102125619A (en) | 2010-01-12 | 2010-01-12 | Chinese medicinal compound for adjunctively reducing blood sugar |
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| CN2010100193294A CN102125619A (en) | 2010-01-12 | 2010-01-12 | Chinese medicinal compound for adjunctively reducing blood sugar |
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| CN102125619A true CN102125619A (en) | 2011-07-20 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103549080A (en) * | 2013-10-29 | 2014-02-05 | 黄毅青 | Lung-clearing tea |
| CN103652181A (en) * | 2013-12-04 | 2014-03-26 | 曾玉 | A tartary buckwheat tea beverage |
| CN103750444A (en) * | 2013-12-17 | 2014-04-30 | 安徽金安康生物科技有限公司 | Beverage applicable to diabetic patients and preparation method thereof |
| CN104095122A (en) * | 2014-06-19 | 2014-10-15 | 马鞍山市心洲葡萄专业合作社 | Buckwheat tea for reducing blood sugar and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045088A (en) * | 2006-03-28 | 2007-10-03 | 山西亚宝药业集团股份有限公司 | Medicine composition for treating diabetes and its preparing method |
-
2010
- 2010-01-12 CN CN2010100193294A patent/CN102125619A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045088A (en) * | 2006-03-28 | 2007-10-03 | 山西亚宝药业集团股份有限公司 | Medicine composition for treating diabetes and its preparing method |
Non-Patent Citations (3)
| Title |
|---|
| 冯敏等: "辅助降糖食品的研究现状", 《中国食物与营养》 * |
| 喇万英: "中医消渴病概述", 《华北煤炭医学院学报》 * |
| 王如沾: "糖尿病中药筛选组方思路", 《山东中医杂志》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103549080A (en) * | 2013-10-29 | 2014-02-05 | 黄毅青 | Lung-clearing tea |
| CN103652181A (en) * | 2013-12-04 | 2014-03-26 | 曾玉 | A tartary buckwheat tea beverage |
| CN103750444A (en) * | 2013-12-17 | 2014-04-30 | 安徽金安康生物科技有限公司 | Beverage applicable to diabetic patients and preparation method thereof |
| CN104095122A (en) * | 2014-06-19 | 2014-10-15 | 马鞍山市心洲葡萄专业合作社 | Buckwheat tea for reducing blood sugar and preparation method thereof |
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Application publication date: 20110720 |