CN102114113A - 一种白头翁汤颗粒剂的制备方法 - Google Patents
一种白头翁汤颗粒剂的制备方法 Download PDFInfo
- Publication number
- CN102114113A CN102114113A CN2010100280131A CN201010028013A CN102114113A CN 102114113 A CN102114113 A CN 102114113A CN 2010100280131 A CN2010100280131 A CN 2010100280131A CN 201010028013 A CN201010028013 A CN 201010028013A CN 102114113 A CN102114113 A CN 102114113A
- Authority
- CN
- China
- Prior art keywords
- extraction
- radix pulsatillae
- granule
- preparation
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008187 granular material Substances 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims description 14
- 241000206469 Pulsatilla Species 0.000 title abstract description 4
- 238000000605 extraction Methods 0.000 claims abstract description 23
- 239000000284 extract Substances 0.000 claims abstract description 6
- 239000009806 pulsatillae Substances 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 239000008589 Cortex Fraxini Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000003809 water extraction Methods 0.000 claims description 6
- 239000004375 Dextrin Substances 0.000 claims description 3
- 229920001353 Dextrin Polymers 0.000 claims description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- 239000002671 adjuvant Substances 0.000 claims description 3
- 235000019425 dextrin Nutrition 0.000 claims description 3
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 3
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 229920000858 Cyclodextrin Polymers 0.000 claims description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 235000021050 feed intake Nutrition 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000741 silica gel Substances 0.000 claims 1
- 229910002027 silica gel Inorganic materials 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 238000009835 boiling Methods 0.000 abstract description 9
- 239000004615 ingredient Substances 0.000 abstract description 7
- 239000003814 drug Substances 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 238000005520 cutting process Methods 0.000 abstract description 2
- 241000099774 Cuscuta salina Species 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000012567 medical material Substances 0.000 description 10
- 230000004087 circulation Effects 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 208000012271 tenesmus Diseases 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
提取方法 | 药材浸膏收率% | 浸膏中白头翁B4的含量 | 浸膏中盐酸小糪碱的含量 |
沸腾煎煮方法 | 25% | 42mg/g | 30mg/g |
低温循环动态提取 | 18% | 60mg/g | 42mg/g |
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010028013A CN102114113B (zh) | 2010-01-05 | 2010-01-05 | 一种白头翁汤颗粒剂的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010028013A CN102114113B (zh) | 2010-01-05 | 2010-01-05 | 一种白头翁汤颗粒剂的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102114113A true CN102114113A (zh) | 2011-07-06 |
CN102114113B CN102114113B (zh) | 2012-09-12 |
Family
ID=44213113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201010028013A Expired - Fee Related CN102114113B (zh) | 2010-01-05 | 2010-01-05 | 一种白头翁汤颗粒剂的制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102114113B (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102526302A (zh) * | 2011-12-31 | 2012-07-04 | 郑州后羿制药有限公司 | 一种抑制仔猪细菌性痢疾的中药微生态制剂及其制备方法 |
CN102697930A (zh) * | 2012-06-15 | 2012-10-03 | 李良 | 治疗痢疾的凤尾草中药汤剂及制备方法 |
CN102973702A (zh) * | 2012-08-23 | 2013-03-20 | 郑州后羿制药有限公司 | 一种用于治疗仔猪黄白痢的复方中药组合物及其制备方法 |
CN104257826A (zh) * | 2014-09-24 | 2015-01-07 | 河南亚卫动物药业有限公司 | 一种畜禽用中药白头翁发酵颗粒及其制备方法 |
CN104922636A (zh) * | 2015-06-16 | 2015-09-23 | 黑龙江中医药大学 | 一种地黄饮子颗粒 |
CN113884587A (zh) * | 2021-08-25 | 2022-01-04 | 广西中医药大学 | 一种白头翁汤多组分化学成分含量测定方法 |
-
2010
- 2010-01-05 CN CN201010028013A patent/CN102114113B/zh not_active Expired - Fee Related
Non-Patent Citations (2)
Title |
---|
时维静,等: "白头翁汤提取工艺试验研究", 《中国实验方剂学杂志》 * |
时维静,等: "综合评分法优化白头翁汤提取工艺", 《中国中医药科技》 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102526302A (zh) * | 2011-12-31 | 2012-07-04 | 郑州后羿制药有限公司 | 一种抑制仔猪细菌性痢疾的中药微生态制剂及其制备方法 |
CN102697930A (zh) * | 2012-06-15 | 2012-10-03 | 李良 | 治疗痢疾的凤尾草中药汤剂及制备方法 |
CN102973702A (zh) * | 2012-08-23 | 2013-03-20 | 郑州后羿制药有限公司 | 一种用于治疗仔猪黄白痢的复方中药组合物及其制备方法 |
CN102973702B (zh) * | 2012-08-23 | 2014-12-17 | 郑州后羿制药有限公司 | 一种用于治疗仔猪黄白痢的复方中药组合物及其制备方法 |
CN104257826A (zh) * | 2014-09-24 | 2015-01-07 | 河南亚卫动物药业有限公司 | 一种畜禽用中药白头翁发酵颗粒及其制备方法 |
CN104922636A (zh) * | 2015-06-16 | 2015-09-23 | 黑龙江中医药大学 | 一种地黄饮子颗粒 |
CN104922636B (zh) * | 2015-06-16 | 2018-11-30 | 黑龙江中医药大学 | 一种地黄饮子颗粒 |
CN113884587A (zh) * | 2021-08-25 | 2022-01-04 | 广西中医药大学 | 一种白头翁汤多组分化学成分含量测定方法 |
Also Published As
Publication number | Publication date |
---|---|
CN102114113B (zh) | 2012-09-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU658614B2 (en) | Pharmaceutical compositions for the treatment of skin disorders | |
CN102114113B (zh) | 一种白头翁汤颗粒剂的制备方法 | |
CN101972395B (zh) | 一种舒缓减压中药组合物及其制备方法 | |
US20110318438A1 (en) | Pharmacologically effective composition of herbs for treatment on symptoms of influenza and colds | |
Zheng et al. | Ephedrae herba: A comprehensive review of its traditional uses, phytochemistry, pharmacology, and toxicology | |
CN105560884A (zh) | 一种治疗狗肺炎的药物组合物及其制备方法 | |
CN103479963A (zh) | 一种治疗类风湿关节炎的中药胶囊及其制备方法 | |
CN104013929B (zh) | 一种治疗风湿性关节炎和类风湿性关节炎的风湿祛痛药物及制备方法 | |
CN102266487B (zh) | 治疗高脂血症的含葛根组合物及制备方法和应用 | |
CN103520456A (zh) | 一种治疗感冒伤风止咳的复方中药颗粒剂 | |
KR20160043430A (ko) | 탈모 예방 또는 발모 촉진, 또는 모발의 보윤·보습용 조성물 및 이의 제조방법 | |
CN104491359B (zh) | 一种治疗口腔溃疡、咽炎肿痛的中药组合物及其制备方法 | |
CN104758358A (zh) | 一种用于湿疹的药物组合物及其制备方法 | |
CN105343847A (zh) | 一种含有艾叶的治疗湿疹的中药组合物及其制备方法 | |
CN104800317A (zh) | 一种预防和治疗鸡球虫的中药组合物及制备方法 | |
CN103599442A (zh) | 一种制备咽炎片的新方法 | |
CN103919972B (zh) | 一种抗疲劳的药物组合物及其制备方法和应用 | |
CN107334988B (zh) | 一种治疗肺痈的中药组合物 | |
CN113101331B (zh) | 一种百里香药茶及其制备方法和应用 | |
CN115252729B (zh) | 一种治疗糖尿病的中药组合物及其应用 | |
CN112057535B (zh) | 一种预防或/和治疗血脂异常的中药组合物的制备方法 | |
CN103006835B (zh) | 具有降血脂和通便功效的药物组合物及其制备方法 | |
CN102058825B (zh) | 一种治疗肝炎的中药组合物及其制备方法 | |
CN110448622B (zh) | 治疗热性感冒的药物及其制备方法和应用 | |
CN106376928A (zh) | 一种辅助降血糖的复方铁皮石斛保健品制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C53 | Correction of patent of invention or patent application | ||
CB02 | Change of applicant information |
Address after: 610041, No. 3, No. 6, building A, building 1, high tech incubator Park, South Tianfu Road, Chengdu hi tech Zone, Sichuan, China Applicant after: Sichuan Dihon Medical Development Co., Ltd. Co-applicant after: Dihon Pharmaceutical Group Co., Ltd. Co-applicant after: Yunnan Dihon Pharmaceutical Co., Ltd. Address before: 610041, No. 3, No. 6, building A, building 1, high tech incubator Park, South Tianfu Road, Chengdu hi tech Zone, Sichuan, China Applicant before: Sichuan Dihon Medical Development Co., Ltd. Co-applicant before: Kuning Dianhong Pharmaceutical Co., Ltd. Co-applicant before: Yunnan Dihon Pharmaceutical Group Co., Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: DIHON PHARMACEUTICAL GROUP CO., LTD. Free format text: FORMER OWNER: DIHON PHARMACEUTICAL GROUP CO., LTD. YUNNAN DIHON PHARMACEUTICAL CO., LTD. Effective date: 20130220 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20130220 Address after: 610041, No. 3, No. 6, building A, building 1, high tech incubator Park, South Tianfu Road, Chengdu hi tech Zone, Sichuan, China Patentee after: Sichuan Dihon Medical Development Co., Ltd. Patentee after: Dihon Pharmaceutical Group Co., Ltd. Address before: 610041, No. 3, No. 6, building A, building 1, high tech incubator Park, South Tianfu Road, Chengdu hi tech Zone, Sichuan, China Patentee before: Sichuan Dihon Medical Development Co., Ltd. Patentee before: Dihon Pharmaceutical Group Co., Ltd. Patentee before: Yunnan Dihon Pharmaceutical Co., Ltd. |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20160720 Address after: 650106 Kunming science and Technology Development Zone, Yunnan Province Road No. 45 Patentee after: Dihon Pharmaceutical Group Co., Ltd. Address before: 610041, No. 3, No. 6, building A, building 1, high tech incubator Park, South Tianfu Road, Chengdu hi tech Zone, Sichuan, China Patentee before: Sichuan Dihon Medical Development Co., Ltd. Patentee before: Dihon Pharmaceutical Group Co., Ltd. |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120912 Termination date: 20190105 |