CN102114110A - Granules with function of obesity treatment and preparation method thereof - Google Patents
Granules with function of obesity treatment and preparation method thereof Download PDFInfo
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Abstract
The invention relates to granules for treating obesity and a preparation method thereof. The granules are prepared by the method comprising the following steps of: weighing finger citron, dogwood, 5 to 7 parts of lucid ganoderma, lotus leaf, cassia seed and ginkgo leaf according to weight parts; mixing the component raw materials; decocting twice by adding water, wherein water in an amount which is 10 times the weight of the raw materials is added for the first time for decocting for 2 hours, and water in an amount which is 8 times the weight of the raw materials is added for the second time for decocting for 1.5 hours; filtering decoction extract obtained by the two operations by using a sieve with the meshes of between 160 and 180 respectively; concentrating filtrate until the density is 1.23 to 1.26g/cm<3> to obtain extract; and mixing the extract and dextrin in a weight part ratio of 1:(2.5-3.5) for granulation to obtain the granules. The granules can regulate blood fat, ensure that people are clear-minded, relaxed and refreshed, and improve the quality of life.
Description
Technical field
The present invention relates to a kind of granule and preparation method thereof, particularly relate to a kind of fat granule and preparation method thereof for the treatment of.
Background technology
Obesity (obestity) is a kind of chronic disease, occupies World Health Organization (WHO) and estimates that it is human face at present the easiest to be out in the cold, kind of the disease but sickness rate sharply rises.
Simple Obesity is that proportion is the highest in all obesity, reaching about 95%, just is the obesity that non-disease causes in brief, and this class patient total body fat distributes more even, do not have the endocrine confusion phenomena, do not have its family of dysbolismus disease yet fat medical history is often arranged.
Obesity influences the labour force, suffers wound easily: fat people is because of weight increase, and the heavy burden of each organ of health all increases, and can cause lumbago, arthralgia, dyspepsia, asthma; Often To Be Protected from Heat for the people of body obesity, hyperhidrosis, skin wrinkle place dermatitis, scratch easily take place, and merge suppurative or fungal infection easily; Also suffer various wounds easily, fracture and sprain etc. because of handicapped.Obesity is a health of people life-prolonging natural enemy: scientist discovers that the concurrent cerebral embolism of overweight people is higher 1 times than normal type person with the sickness rate of heart failure, suffers from coronary heart disease, hypertension, diabetes, the cholelithiasis person is than the high 3-5 of normal person times, because the invasion and attack of these diseases, people's life-span will obviously shorten.The obese people easily suffers from endocrine and metabolic disease: because obesity causes internal metabolism and cryptorrhea, often can cause that multiple metabolic disease is as diabetes, hyperlipemia, hyperuricemia etc., female irregular menstruation etc.Fat all right concurrent sleep apnea syndrome, phlebothrombosis, the danger that increases anesthesia and perform the operation.The fat sickness rate that can also increase malignant tumor, obese women carcinoma of endometrium are than the high 2-3 of normal women doubly.The incidence rate of obese males colon cancer, rectal cancer and carcinoma of prostate is than normal person's height.
Summary of the invention
The purpose of this invention is to provide a kind of can blood lipid regulation, make human body clearheaded, health is light, and is refreshed, the granule with the fat function of treatment of improving the quality of living.
Another object of the present invention provides a kind of preparation method with granule of the fat function of treatment.
The present invention adopts following technical scheme:
A kind of granule with the fat function of treatment, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 25～30 parts of Fructus Citri Sarcodactylis, 10～13 parts of Fructus Corni, 5～7 parts of Ganodermas, 20～25 parts of 30～39 parts on Folium Nelumbinis and Semen Cassiaes, 5～7 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number.
A kind of preparation method with granule of the fat function of treatment, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 25～30 parts of Fructus Citri Sarcodactylis, 10～13 parts of Fructus Corni, 5～7 parts of Ganodermas, 20～25 parts of 30～39 parts on Folium Nelumbinis and Semen Cassiaes, 5～7 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number.
The invention has the beneficial effects as follows: the patient can with granule of the present invention according to every day 6～12g amount directly take after mixing it with water, be a kind of green health solid beverage that is applicable to obese people.
Granule treatment obesity of the present invention has following characteristics:
1, safety: product of the present invention is selected natural plants not only edible but also can be medicinal for use, has no side effect environmental protection.
2, convenient: use product of the present invention, the patient is easy to use, and therapeutic effect is good.
3, evident in efficacy: as to use product of the present invention, hyperlipidemia obese patient blood fat is reduced, alleviate abdominal obesity, the symptom of alleviation physical fatigue etc.
In the granules medicine prescription of the present invention, the effect of each crude drug is:
Fructus Citri Sarcodactylis: suffering, hardship, sweet, temperature, nontoxic, go into liver, spleen, stomach three warps, multiple medicinal functions such as activating QI to eliminate phlegm, cough-relieving relieving distension, the liver soothing and the spleen invigorating stomach function regulating are arranged." book on Chinese herbal medicine is new again " calls it can control the gas soothing liver-QI.The catharsis function of liver is whole body QI movement being in harmonious way then normally, QI and blood and accent, and meridians tonneau, the functional activity of internal organs organ are kept normally, and the defeated cloth metabolism side of the operation of blood, body fluid and cereal nutrient is able to normally.If the liver imbalance is smooth, whether mechanism of qi disorder then this liter or not, and cereal nutrients such as blood glucose can not stagnate in blood with the defeated cloth of the gas of the clear sun whole body, hyperglycemia occurs.Or do not fall and fall, to let out under precise and tiny, glucose in urine appears.Further cause the defeated cloth disorder of other cereal nutrients such as fat, protein, cause many complication.
Be monarch drug with the Fructus Citri Sarcodactylis in the side, depressed liver-energy dispersing and QI regulating is complied with liver bar soothing the liver.
Fructus Corni: liver and kidney tonifying, essence astringing and desertion stemming.Be used for vertigo and tinnitus, soreness of waist and knee joint, interior-heat is quenched one's thirst.Modern pharmacology studies show that Fructus Corni has antiinflammatory, antibiotic, effects such as anti-stress, antioxidation, blood fat reducing.
Ganoderma: cure mainly asthenia, insomnia, cough, asthma, dyspepsia, malignant tumor etc.Modern pharmacology studies show that Ganoderma has antitumor, protecting liver and detoxication, the anti-ageing effect of waiting for a long time.
Folium Nelumbinis: delicate fragrance rises looses; Has summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, dissipating blood stasis hemostatic effect.Modern pharmacology studies show that Folium Nelumbinis has effect for reducing blood fat.
Be ministerial drug with Fructus Corni, Ganoderma, Folium Nelumbinis in the side, supplementing QI and nourishing YIN, auxiliary monarch drug performance curative effect.
Semen Cassiae: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Be used for the puckery pain of conjunctival congestion, the many tears of photophobia, it is dizzy to have a headache, poor vision, constipation.Modern pharmacology studies show that, Semen Cassiae has antibiotic, blood fat reducing, blood pressure lowering, effects such as anti-platelet aggregation.
Folium Ginkgo: astringe the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving.Be used for the cough due to deficiency of the lung, modern pharmacology studies show that, Folium Ginkgo is to coronary heart disease, angina pectoris, hyperlipidemia, the intrinsic certain effect of anticoagulant.
Be adjuvant with Semen Cassiae, Folium Ginkgo in the side, all medicines in the mediation side are corrected each medicine property of medicine.
It is as follows to adopt the present invention to treat fat clinical treatment standard:
Use granule of the present invention every day 1-2 time, each 6-10g, 8 weeks were a course of treatment;
The standard of produce effects is: use 1 course of treatment of granule of the present invention, (subcutaneous fat reduces 〉=1.5cm) obviously improves, and triglyceride, cholesterol, the overall improvement of three indexs of high density lipoprotein surpass 70% in fundamental symptoms.
Effectively standard is: uses 1 course of treatment of granule of the present invention, (subcutaneous fat reduces by 0.5-1.5cm) basic change, and triglyceride, cholesterol, three indexs of high density lipoprotein are totally improved between 30%-70% in fundamental symptoms.
Invalid standard is: use 1 course of treatment of granule of the present invention, fundamental symptoms (subcutaneous fat reduces≤and 0.5cm) not have obviously and improve, triglyceride, cholesterol, three indexs of high density lipoprotein are totally improved less than 30%.
Patient's 268 examples that are put to the test are diagnosed as obesity through hospital above county level, no severe cardiac Liver and kidney complication, and at 27～70 years old age, the edible food that adds unguentum of the present invention of experimental group was taken 56 days continuously, and test-meal group produce effects case 108 people account for 40.3% of test-meal group sum; Effectively case 100 people account for 37.3% of test-meal group sum; Invalid case 60 people account for 22.4% of test-meal group sum.
Model case:
Lee * *, woman, 45 years old, fat history 4 years, triglyceride 2.0 mmol/L when going into to organize, cholesterol 8.0 mmol/L, high density lipoprotein 0.6 mmol/L, use granule of the present invention after 8 weeks, subcutaneous fat reduces 1.6cm, triglyceride 1.6 mmol/L, cholesterol 5 mmol/L, HDL1 .3 mmol/L, blood lipids index is obviously improved.
The hole * *, man, 55 years old, fat history 3 years, triglyceride 2.3 mmol/L when going into to organize, cholesterol 7.0 mmol/L, high density lipoprotein 0.3 mmol/L, use granule of the present invention after 8 weeks, subcutaneous fat reduces 2.0cm, triglyceride 1.7 mmol/L, cholesterol 4 mmol/L, HDL1 .7 mmol/L, blood lipids index is obviously improved.
Literary composition * *, woman, 48 years old, fat history 4 years, triglyceride 3.3 mmol/L when going into to organize, cholesterol 8.5 mmol/L, high density lipoprotein 0.4 mmol/L, use granule of the present invention after 8 weeks, subcutaneous fat reduces 1.8cm, triglyceride 0.9 mmol/L, cholesterol 6 mmol/L, HDL1 .6 mmol/L, blood lipids index is obviously improved.
Open * *, man, 35 years old, fat history 2 years, triglyceride 2.5 mmol/L when going into to organize, cholesterol 6.5 mmol/L, high density lipoprotein 0.3mmol/L, use granule of the present invention after 8 weeks, subcutaneous fat reduces 1.7cm, triglyceride 1.3mmol/L, cholesterol 4.5 mmol/L, HDL1 .8 mmol/L, blood lipids index is obviously improved.
The specific embodiment
Content of the present invention is, a kind of preparation method that is used for the treatment of fat granule, and it adopts following ratio of weight and number component:
Embodiment 1
A kind of granule with the fat function of treatment is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 25 parts of Fructus Citri Sarcodactylis, 10 parts of Fructus Corni, 7 parts of Ganodermas, 25 parts of 30 parts on Folium Nelumbinis and Semen Cassiaes, 6 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.23g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5 promptly gets described granule according to ratio of weight and number.
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.25g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number.
A kind of preparation method of granule with the fat function of treatment is characterized in that it is made up of following steps: the first step: take by weighing by weight: 25 parts of Fructus Citri Sarcodactylis, 10 parts of Fructus Corni, 7 parts of Ganodermas, 30 parts on Folium Nelumbinis and 25 parts of Semen Cassiaes, 6 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.26g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3.5 promptly gets described granule according to ratio of weight and number.
Embodiment 2
A kind of granule with the fat function of treatment is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 30 parts of Fructus Citri Sarcodactylis, 12 parts of Fructus Corni, 7 parts of Ganodermas, 20 parts of 36 parts on Folium Nelumbinis and Semen Cassiaes, 7 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 160 mesh sieves respectively, and it is 1.23g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3.5 promptly gets described granule according to ratio of weight and number.
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5 promptly gets described granule according to ratio of weight and number.
A kind of preparation method of granule with the fat function of treatment is characterized in that it is made up of following steps: the first step: take by weighing by weight: 30 parts of Fructus Citri Sarcodactylis, 12 parts of Fructus Corni, 7 parts of Ganodermas, 36 parts on Folium Nelumbinis and 20 parts of Semen Cassiaes, 7 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, add the water of 8 times of weight for the second time, decocted 1.5 hours, twice decoction extracting solution filters with 180 mesh sieves respectively, and it is 1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5 promptly gets described granule according to ratio of weight and number.
Embodiment 3
A kind of granule with the fat function of treatment is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 25 parts of Fructus Citri Sarcodactylis, 10 parts of Fructus Corni, 5 parts of Ganodermas, 25 parts of 39 parts on Folium Nelumbinis and Semen Cassiaes, 5 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5 promptly gets described granule according to ratio of weight and number.
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.26g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3 promptly gets described granule according to ratio of weight and number.
A kind of preparation method of granule with the fat function of treatment is characterized in that it is made up of following steps: the first step: take by weighing by weight: 25 parts of Fructus Citri Sarcodactylis, 10 parts of Fructus Corni, 5 parts of Ganodermas, 39 parts on Folium Nelumbinis and 25 parts of Semen Cassiaes, 5 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:3.5 promptly gets described granule according to ratio of weight and number.
Claims (2)
1. one kind has the granule for the treatment of fat function, it is characterized in that it being to adopt following method to make: the first step: take by weighing by weight: 25～30 parts of Fructus Citri Sarcodactylis, 10～13 parts of Fructus Corni, 5～7 parts of Ganodermas, 20～25 parts of 30～39 parts on Folium Nelumbinis and Semen Cassiaes, 5～7 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number.
2. preparation method of granule with the fat function of treatment, it is characterized in that it is made up of following steps: the first step: take by weighing by weight: 25～30 parts of Fructus Citri Sarcodactylis, 10～13 parts of Fructus Corni, 5～7 parts of Ganodermas, 20～25 parts of 30～39 parts on Folium Nelumbinis and Semen Cassiaes, 5～7 parts of Folium Ginkgos; Second step: the said components raw material is mixed, decoct with water twice, add the water of 10 times of weight for the first time, decocted 2 hours, and added the water of 8 times of weight for the second time, decocted 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number;
Or, add 70% alcohol reflux twice with the mixing of said components raw material, and add 8 times of amounts of 70% ethanol for the first time, extract and refluxed 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and refluxed 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol is concentrated into density 1.23～1.26g/cm
3, extractum, be described extractum and dextrin that the mixed granulation of 1:2.5～3.5 promptly gets described granule according to ratio of weight and number.
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Cited By (1)
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| CN104225014A (en) * | 2014-10-08 | 2014-12-24 | 久美彭措 | Tibetan medicine for treating diabetes |
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| CN101467577A (en) * | 2007-12-27 | 2009-07-01 | 天津天阜康生物技术发展有限公司 | Lipid-lowering tea and preparation method thereof |
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| CN104225014A (en) * | 2014-10-08 | 2014-12-24 | 久美彭措 | Tibetan medicine for treating diabetes |
| CN104225014B (en) * | 2014-10-08 | 2016-03-09 | 久美彭措 | A kind of Tibetan medicine for the treatment of diabetes |
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| CN102114110B (en) | 2014-04-02 |
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