CN102113981A - Non-rinse pregnant woman perineum medical care gel and preparation method thereof - Google Patents
Non-rinse pregnant woman perineum medical care gel and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a non-rinse pregnant woman perineum medical care gel and a preparation method thereof. The gel comprises the following components in percentage by weight: 0.1 to 5 percent of water-soluble chitosan, 0.3 to 1 percent of A.SAP natural organic fungicide, 0.1 to 0.5 percent of aloe extract, 0.3 to 1.5 percent of water-soluble polymer gel material, 0.1 to 1 percent of triethanolamine, 0.05 to 0.5 percent of chelating agent, 0.05 to 0.5 percent of emollient and the balance of distilled water, and is prepared by dissolving the components in the distilled water and uniformly mixing the solution. The chitosan non-rinse pregnant woman perineum medical care gel has the effects of cleaning perineum, removing dirt, promoting blood circulation and enhancing immunity of the perineum part and is antibacterial and antiviral; most importantly, the medical care gel has high using safety performance and does not have any adverse effect on a fetus in a pregnant woman. The medical care gel is easy and convenient to produce, is environmentally-friendly during production and is suitable for mass industrial production.
Description
Technical field
The present invention relates to a kind of flushing free anemia of pregnant woman perineum medical treatment and nursing gel and preparation method thereof.
Background technology
After anemia of pregnant woman's pregnancy, because functions of hormones, the secretions increase of the lower part of the body, pudendum humidity are easy to breed bacteria; Simultaneously, anemia of pregnant woman's resistance has also descended, than ordinary person easy infection antibacterial more, so various gynecological inflammation just is wrapped with " ready-to-be mother " easily.Generally speaking, anemia of pregnant woman's colpitis mycotica more sees; So anemia of pregnant woman's perineal position is infected extremely easily.The anemia of pregnant woman carries out the medical cleaning-nursing of perineal position in period of pregnancy, just seems very important.
At present the anemia of pregnant woman just cleaned with clear water in period of pregnancy during the perineal position cleaning, there is no the effect that sterilizing and anti-virus, antiinflammatory alleviate hyperemia and edema, antiallergic, increase perineum local immunity power and blood circulation promoting; And a large amount of flushing with clean water, also very inconvenient to the anemia of pregnant woman.In addition, when both having made the anemia of pregnant woman perineal position be carried out general nursing, also only be to use 1: 5000 potassium permanganate solution drip washing pudendum, play the effect of corrosion-proof and sterilization in the pregnancy period.But, potassium permanganate be a kind of oxidability very strong, have corrosive chemical drugs, this antiseptic not only can kill pathogenic organisms, can kill equally and colonize in the human body, healthy and helpful normal flora, the ecological balance that long-term often use then can destroy body local brings out other infection.In addition, some anemia of pregnant woman even use some compound Chinese herb gynecological flushing liquors on the market, but these washing liquids often only play the effect that suppresses antibacterial, there is no the effect of others.And some " ready-to-be mothers " if use the medicine washing vagina, also are inappropriate after suffering from gynecological inflammation.Because owing to do not know the depth of things, very easily cause threatened abortion or miscarriage during flushing.In addition, the too big crank of anemia of pregnant woman's belly cleans the lower part of the body every night and squats not go down, so also also inconvenient with a large amount of flushing with clean water or bathing perineal position.
Therefore, be badly in need of a kind of medical supplies of exempting from the water flushing of the anemia of pregnant woman's of being used for perineal position on the Chinese market, its dirty function that not only has cleaning, cleans and dispel, also should possess anti-bacteria and anti-virus, antiinflammatory and impel that local inflammation disappears, the effect of blood circulation promoting, more should in use have no effect, could really satisfy the actual demand of anemia of pregnant woman's perineal position medical treatment and nursing fetus.
Summary of the invention
The objective of the invention is provides a kind of flushing free anemia of pregnant woman perineum medical treatment and nursing gel and preparation method thereof in order to overcome defective and the problem that above-mentioned prior art exists.Flushing free anemia of pregnant woman perineum medical treatment and nursing gel not only has the local dirty effect of dispelling that cleans, and also has sterilizing and anti-virus, strengthens the effect of local immunity power; And safety non-toxic, chafe and mucosa do not influence foetus health yet.Its preparation process is simple, and is with low cost, can satisfy the actual medical demand of anemia of pregnant woman's perineal position fully.
Technical scheme of the present invention is:
A kind of flushing free anemia of pregnant woman perineum medical treatment and nursing gel comprises following component:
Water-soluble chitosan 0.1-5%
Corn extract quaternary ammonium salt cationic Surface Active Germicide ASAP 0.3-1%
Aloe extract 0.1-0.5%
Water soluble polymer gel rubber material 0.3-1.5%
Triethanolamine 0.1-1%
Chelating agen 0.05-0.5%
Emollient 0.05-0.5%
Distilled water surplus.
Above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel, described water-soluble chitosan are one or two or more kinds the mixture in carboxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan, the N-trimethyl oxidation chitosan.Water-soluble chitosan among the present invention all can be buied in market.
Above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel, described corn extract quaternary ammonium salt cationic Surface Active Germicide is buied from Foochow Sheng Deli Information Technology Co., Ltd.
Above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel, described aloe extract is by the aloe extract that obtains from Folium Aloe.Aloe extract among the present invention is buied from market.
Above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel, described water-soluble high-molecular material is that the composite water soluble polymer gel of crosslinked polypropylene acid resin, crosslinked polypropylene acid resin and hydroxyethyl-cellulose combination is handed over or connection polyacrylic resin and the composite water soluble polymer gel of hydroxypropyl cellulose combination, the composite water soluble polymer gel of preferred crosslinked polypropylene acid resin and hydroxyethyl-cellulose combination is handed over or connection polyacrylic resin and the composite water soluble polymer gel of hydroxypropyl cellulose combination, can form the composite substrate of gel, form fine and smooth stabilizing gel.
Above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel, one or both mixture in citric acid, sodium citrate, potassium citrate, calcium citrate, tartaric acid, sodium tartrate, Soluble tartar., Calcium d-tartrate, triethyl sodium ethylene diamine tetracetate, triethyl ethylenediamine tetraacetic acid (EDTA) potassium, triethyl ethylenediamine tetraacetic acid (EDTA) calcium, sodium gluconate, Fructus Vitis viniferae acid potassium, the calcium gluconate.Preferred triethyl sodium ethylene diamine tetracetate, triethyl ethylenediamine tetraacetic acid (EDTA) potassium, triethyl ethylenediamine tetraacetic acid (EDTA) calcium, itself and most metal ions have chelation.
Above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel, described emollient is one or more mixture in glycerol, vitamin A, vitamin C, vitamin E, lanoline, the lactic acid.
A kind of preparation method of flushing free anemia of pregnant woman perineum medical treatment and nursing gel comprises the steps:
A) natural organic bactericide of ASAP and emollient are dissolved in the part distilled water, left standstill 1-15 hour;
B) the water soluble polymer gel rubber material is dissolved in the part distilled water, makes solution;
C) water-soluble chitosan, aloe extract and chelating agen are dissolved in the part distilled water, make solution;
D) triethanolamine is dissolved in the part distilled water, makes solution;
E) with the mixed solution that makes in the step a), under agitation, after adding the water soluble polymer gel rubber material solution that makes in the step b), continue to stir 5-30 minute, supply the residue distilled water, and under stirring, add water-soluble chitosan, aloe extract and the chelating agent solution that makes in the step c);
F) with e) solution that makes, under stirring, add in the step d) and make triethanolamine solution, make gel.
The preparation method of above-mentioned flushing free anemia of pregnant woman perineum medical treatment and nursing gel wherein, also comprises step g), g) gel that makes is made finished product, adopts the disinfection with high pressure steam sterilization, the aseptic level gel that makes.Finished product in the laggard horizontal high voltage vapor sterilization sterilization of Production and Packaging, had both been kept the sterilizing ability of manufactured goods, the thorough aseptic condition that has kept manufactured goods itself again, significant for the secondary infection of prevention anemia of pregnant woman perineal position.
In the flushing free anemia of pregnant woman perineum medical treatment and nursing gel of the present invention, select the water-soluble chitosan natural bactericidal agent for use, can not only be fast, effectively and wide spectrum ground pathogenic microbe killing, also have antiinflammatory and regulate immunocompetent effect, more importantly be that it does not have any stimulation to mucosa, and without any side effects to fetus, this makes and more is applicable to the cleaning and the medical treatment and nursing of anemia of pregnant woman's perineum part by this flushing free anemia of pregnant woman perineum medical treatment and nursing gel.Water-soluble chitosan has better antibacterial activity, can suppress the growth and breeding of some funguses, antibacterial and virus.Water-soluble chitosan has the series of biologic that activates airframe systems, mediation airframe systems and learns effect, improves cytophagous systemic-function.The macrophage surface exists the receptor of bacterial polysaccharides, and water-soluble chitosan is as the analog of bacterial polysaccharides, can stimulate macrophage activation, produce following reaction: promote its phagocytic function, strengthen its cooperative effect in other immunne response, thereby realize the adjusting of body, the cellullar immunologic response and the humoral immunoresponse(HI) of mediation body to T cell, NK cell and B cell.Therefore, shell water solublity polysaccharide has the partial immunological enhancement of anemia of pregnant woman's perineum.
In the flushing free anemia of pregnant woman perineum medical treatment and nursing gel of the present invention, select for use corn extract quaternary ammonium salt cationic Surface Active Germicide ASAP that antibacterial and virus are had quick killing action, the function that extremely strong removal abnormal flavour is arranged, and has tight security, non-stimulated to mucosa, external does not have influence to fetus.
In the flushing free anemia of pregnant woman perineum medical treatment and nursing gel of the present invention, select aloe extract for use, can strengthen further that this gel is antibacterial to anemia of pregnant woman's perineal position, effect such as antiinflammatory, antipruritic, convergence and pain relieving; It also can strengthen the antiallergic ability of anemia of pregnant woman's perineal position.
The present invention adopts triethanolamine to be used for and the crosslinked polypropylene acid resin as nertralizer, is neutral and presents gel form; And triethanolamine is in process of production to operator's avirulence.
Flushing free anemia of pregnant woman perineum medical treatment and nursing gel of the present invention can play effective medical treatment and nursing effect to anemia of pregnant woman's perineum part, and fetus is had no side effect.Flushing free anemia of pregnant woman perineum medical treatment and nursing gel of the present invention has sterilizing and anti-virus, strengthens local immunity power, antipruritic and antianaphylactic function.And the preparation method of flushing free anemia of pregnant woman perineum medical treatment and nursing gel of the present invention is simple, with low cost, free from environmental pollution, helps large-scale industrial production.
The specific embodiment
Describe the present invention in detail below in conjunction with embodiment.Should be understood that these embodiment only to be used to the present invention is described and be not used in and limit the scope of the invention.The ASAP washing liquid antibacterial that ASAP in the present embodiment buys from Foochow Sheng Deli Information Technology Co., Ltd.
Embodiment 1
The preparation gross weight is the flushing free anemia of pregnant woman perineum medical treatment and nursing gel of 1000 grams:
The first step is dissolved in 3 gram ASAP and 1 gram vitamin E in the distilled water of 50 grams, leaves standstill 12 hours;
Second step was dissolved in 5 gram crosslinked polypropylene acid resins and 5 gram hydroxyethyl-celluloses in the distilled water of 250 grams, obtained the mixed solution of crosslinked polypropylene acid resin and hydroxyethyl-cellulose;
In the 3rd step, 50 gram carboxymethyl chitosans, 10 gram triethyl sodium ethylene diamine tetracetates and 1 gram aloe extract are dissolved in the 150 gram distilled water;
In the 4th step, 10 gram triethanolamine are dissolved in the 50 gram distilled water;
The 5th step, the solution that contains ASAP and emollient that the first step is obtained under agitation, add in the mixed solution of the second crosslinked polypropylene acid resin that obtain of step and hydroxyethyl-cellulose, continue to stir 5 minutes, supply the distilled water of surplus by weight, and under stirring, add the solution that the 3rd step gained contains carboxymethyl chitosan, aloe extract and triethyl sodium ethylene diamine tetracetate;
In the 6th step, the 5th step gained solution adds the triethanolamine solution that the 4th step made under stirring, can get the milky gel.
The 7th step, manufactured goods are made in the gel packing in the step 6, carry out the disinfection with high pressure steam sterilization, the aseptic level gel that makes.
The outward appearance of the gel that embodiment 1 makes and result of use check:
1) the concrete parameter of flushing free anemia of pregnant woman perineum medical treatment and nursing gel that makes in the present embodiment is as shown in table 1.
The physics and chemistry technical specification testing result of the gel that makes among table 1 embodiment 1
| Sequence number | The physics and chemistry technical specification | Unit | Value |
| 1 | Loading amount | g | The 60g/ pipe |
| 2 | Viscosity | Pa.s/m | 8.6 |
| 3 | PH value | / | 6.0 |
Conclusion: physical and chemical index is qualified, and the gel that makes among the embodiment 1 is easy to smearing, and coats after the perineum part, and mucosa is had no stimulation, and usability is good.
2) use the gel that makes among the embodiment 1 to be applied to perineum, detect after being coated with 50 seconds, testing result is as shown in table 2:
The bacteriological detection result of the gel that makes among table 2 embodiment 1
| Test item | Examination criteria | Testing result | Conclusion |
| Total number of bacteria | 0 | 0 | Qualified |
| Staphylococcus aureus | Killing rate 〉=99.9% | ≥99.99％ | Qualified |
| Escherichia coli | Killing rate 〉=99.9% | ≥99.99％ | Qualified |
| Bacillus pyocyaneus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Aerobacteria | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Excrement produces bacillus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Pseudomonas fluorescens | Killing rate 〉=90.0% | ≥99.00％ | Qualified |
| Aspergillus flavus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Bacillus proteus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Bacillus subtilis | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Candida albicans | Killing rate 〉=90.0% | ≥99.00％ | Qualified |
| Hepatitis B surface antigen | Killing rate 〉=99.9% | 100％ | Qualified |
Conclusion: embodiment 1 made gel has stronger sterilizing and anti-virus ability.
Embodiment 2
The preparation gross weight is the flushing free anemia of pregnant woman perineum medical treatment and nursing gel of 1000 grams:
The first step is dissolved in 5 gram ASAP and 0.5 gram vitamin E in the distilled water of 50 grams, leaves standstill 12 hours;
Second step was dissolved in 10 gram crosslinked polypropylene acid resins and 5 gram hydroxyethyl-celluloses in the distilled water of 350 grams, obtained the mixed solution of crosslinked polypropylene acid resin and hydroxyethyl-cellulose;
In the 3rd step, 50 gram hydroxyethyl chitosans, 0.5 gram potassium citrate and 1.5 gram aloe extracts are dissolved in the 200 gram distilled water;
In the 4th step, 10 gram triethanolamine are dissolved in the 100 gram distilled water;
The 5th step, the solution that contains ASAP and emollient that the first step is obtained under agitation, add in the mixed solution of the second crosslinked polypropylene acid resin that obtain of step and hydroxyethyl-cellulose, continue to stir 5 minutes, supply the distilled water of surplus by weight, and under stirring, add the solution that the 3rd step gained contains hydroxyethyl chitosan, aloe extract and potassium citrate;
In the 6th step, the 5th step gained solution adds the triethanolamine solution that the 4th step made under stirring, can get the milky gel;
The 7th step, manufactured goods are made in the gel packing in the step 6, carry out the disinfection with high pressure steam sterilization, the aseptic level gel that makes.
The outward appearance of the gel that embodiment 2 makes and result of use check:
1) the concrete parameter of flushing free anemia of pregnant woman perineum medical treatment and nursing gel that makes in the present embodiment is as shown in table 3.
The physics and chemistry technical specification testing result of the gel that makes among table 3 embodiment 2
| Sequence number | The physics and chemistry technical specification | Unit | Value |
| 1 | Loading amount | g | The 60g/ pipe |
| 2 | Viscosity | Pa.s/m | 9 |
| 3 | PH value | / | 6.5 |
Conclusion: physical and chemical index is qualified, and the gel that makes among the embodiment 1 is easy to smearing, and coats after the perineum part, and mucosa is had no stimulation, and usability is good.
2) use the gel that makes among the embodiment 2 to be applied to perineum, detect after being coated with 50 seconds, testing result is as shown in table 4:
The bacteriological detection result of the gel that makes among table 4 embodiment 2
| Test item | Examination criteria | Testing result | Conclusion |
| Total number of bacteria | 0 | 0 | Qualified |
| Staphylococcus aureus | Killing rate 〉=99.9% | ≥99.99％ | Qualified |
| Escherichia coli | Killing rate 〉=99.9% | ≥99.99％ | Qualified |
| Bacillus pyocyaneus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Aerobacteria | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Excrement produces bacillus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Pseudomonas fluorescens | Killing rate 〉=90.0% | ≥99.00％ | Qualified |
| Aspergillus flavus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Bacillus proteus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Bacillus subtilis | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Candida albicans | Killing rate 〉=90.0% | ≥99.00％ | Qualified |
| Hepatitis B surface antigen | Killing rate 〉=99.9% | 100％ | Qualified |
Conclusion: embodiment 2 made gels have stronger sterilizing and anti-virus ability.
Embodiment 3
The preparation gross weight is the chitosan flushing free anemia of pregnant woman perineum medical treatment and nursing gel of 1000 grams:
The first step is dissolved in 8 gram ASAP and 2 gram vitamin Es in the distilled water of 100 grams, leaves standstill 12 hours;
Second step was dissolved in 2 gram crosslinked polypropylene acid resins and 1 gram hydroxyethyl-cellulose in the distilled water of 250 grams, obtained the mixed solution of crosslinked polypropylene acid resin and hydroxyethyl-cellulose;
In the 3rd step, 30 gram hydroxypropyl chitosans, 5 gram Calcium d-tartrates and 2 gram aloe extracts are dissolved in the 200 gram distilled water;
In the 4th step, 8 gram triethanolamine are dissolved in the 100 gram distilled water;
The 5th step, the solution that contains ASAP and emollient that the first step is obtained under agitation, add in the mixed solution of the second crosslinked polypropylene acid resin that obtain of step and hydroxyethyl-cellulose, continue to stir 5 minutes, supply the distilled water of surplus by weight, and under stirring, add the solution that the 3rd step gained contains hydroxypropyl chitosan, aloe extract and Calcium d-tartrate;
In the 6th step, the 5th step gained solution adds the triethanolamine solution that the 4th step made under stirring, can get the milky gel;
The 7th step, manufactured goods are made in the gel packing in the step 6, carry out the disinfection with high pressure steam sterilization, the aseptic level gel that makes.
The outward appearance of the gel that embodiment 3 makes and result of use check:
1) the concrete parameter of flushing free anemia of pregnant woman perineum medical treatment and nursing gel that makes in the present embodiment is as shown in table 5.
The physics and chemistry technical specification testing result of the gel that makes among table 5 embodiment 3
| Sequence number | The physics and chemistry technical specification | Unit | Value |
| 1 | Loading amount | g | The 60g/ pipe |
| 2 | Viscosity | Pa.s/m | 9.5 |
| 3 | PH value | / | 6.2 |
Conclusion: physical and chemical index is qualified, and the gel that makes among the embodiment 3 is easy to smearing, and coats after the perineum part, and mucosa is had no stimulation, and usability is good.
2) use the gel that makes among the embodiment 3 to be applied to perineum, detect after being coated with 50 seconds, testing result is as shown in table 6:
The bacteriological detection result of the gel that makes among table 2 embodiment 3
| Test item | Examination criteria | Testing result | Conclusion |
| Total number of bacteria | 0 | 0 | Qualified |
| Staphylococcus aureus | Killing rate 〉=99.9% | ≥99.99％ | Qualified |
| Escherichia coli | Killing rate 〉=99.9% | ≥99.99％ | Qualified |
| Bacillus pyocyaneus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Aerobacteria | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Excrement produces bacillus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Pseudomonas fluorescens | Killing rate 〉=90.0% | ≥99.00％ | Qualified |
| Aspergillus flavus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Bacillus proteus | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Bacillus subtilis | Killing rate 〉=99.9% | ≥99.90％ | Qualified |
| Candida albicans | Killing rate 〉=90.0% | ≥99.00％ | Qualified |
| Hepatitis B surface antigen | Killing rate 〉=99.9% | 100％ | Qualified |
Conclusion: embodiment 3 made gels have stronger sterilizing and anti-virus ability.
Embodiment 4
The preparation gross weight is the chitosan flushing free anemia of pregnant woman perineum medical treatment and nursing gel of 1000 grams:
The first step is dissolved in 9 gram ASAP and 3 gram vitamin Es in the 100 gram distilled water, leaves standstill 8 hours;
Second step was dissolved in 5 gram crosslinked polypropylene acid resins in the distilled water of 200 grams, obtained the cross linked polyacrylate resin solution;
In the 3rd step, 1 gram N-trimethyl oxidation chitosan, 1 gram sodium gluconate and 5 gram aloe extracts are dissolved in the 200 gram distilled water;
In the 4th step, 1 gram triethanolamine is dissolved in the 100 gram distilled water;
The 5th step, the solution that contains ASAP and vitamin E that the first step is obtained under agitation, adding second goes on foot in the solution of the crosslinked polypropylene acid resin that obtains, continue to stir 5 minutes, supply the distilled water of surplus by weight, and under stirring, add the solution that the 3rd step gained contains N-trimethyl oxidation chitosan, aloe extract and sodium gluconate;
In the 6th step, the solution with step 5 makes adds triethanolamine solution under stirring, can get the milky gel;
The 7th step, manufactured goods are made in the gel packing in the step 6, carry out the disinfection with high pressure steam sterilization, the aseptic level gel that makes.
The flushing free anemia of pregnant woman perineum medical treatment and nursing gel that present embodiment makes not only has cleaning action, also has the effect of sterilizing and anti-virus and promotion local immunity power; The anemia of pregnant woman uses comfortable; Preparation process is simple, and is with low cost.
Embodiment 5
The preparation gross weight is the chitosan flushing free anemia of pregnant woman perineum medical treatment and nursing gel of 1000 grams:
The first step is dissolved in 10 gram ASAP and 5 gram vitamin Es in the 100 gram distilled water, leaves standstill 8 hours;
Second step was dissolved in 5 gram crosslinked polypropylene acid resins in the distilled water of 200 grams, obtained the cross linked polyacrylate resin solution;
In the 3rd step, 5 gram carboxymethyl chitosans, 1.5 gram triethyl ethylenediamine tetraacetic acid (EDTA) calcium and 4 gram aloe extracts are dissolved in the 200 gram distilled water;
In the 4th step, 1.5 gram triethanolamine are dissolved in the 100 gram distilled water;
The 5th step, the solution that contains ASAP and vitamin E that the first step is obtained under agitation, adding second goes on foot in the solution of the crosslinked polypropylene acid resin that obtains, continue to stir 5 minutes, supply the distilled water of surplus by weight, and under stirring, add the solution that the 3rd step gained contains carboxymethyl chitosan, aloe extract and triethyl ethylenediamine tetraacetic acid (EDTA) calcium;
In the 6th step, the solution with step 5 makes adds triethanolamine solution under stirring, can get the milky gel;
The 7th step, manufactured goods are made in the gel packing in the step 6, carry out the disinfection with high pressure steam sterilization, the aseptic level gel that makes.
The flushing free anemia of pregnant woman perineum medical treatment and nursing gel that present embodiment makes not only has cleaning action, also has the effect of sterilizing and anti-virus and promotion local immunity power; The anemia of pregnant woman uses comfortable; Preparation process is simple, and is with low cost.
Claims (8)
1. flushing free anemia of pregnant woman perineum medical treatment and nursing gel is characterized in that: comprise following component, each component by weight percentage:
Water-soluble chitosan 0.1-5%
Corn extract quaternary ammonium salt cationic Surface Active Germicide ASAP 0.3-1%
Aloe extract 0.1-0.5%
Water soluble polymer gel rubber material 0.3-1.5%
Triethanolamine 0.1-1%
Chelating agen 0.05-0.5%
Emollient 0.05-0.5%
Distilled water surplus.
2. flushing free anemia of pregnant woman perineum medical treatment and nursing gel according to claim 1 is characterized in that: described water-soluble chitosan is one or two or more kinds the mixture in carboxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan, the N-trimethyl oxidation chitosan.
3. flushing free anemia of pregnant woman perineum medical treatment and nursing gel according to claim 1, it is characterized in that: described aloe extract is by the aloe extract that obtains from Folium Aloe.
4. flushing free anemia of pregnant woman perineum medical treatment and nursing gel according to claim 1 is characterized in that: described water-soluble high-molecular material is that the composite water soluble polymer gel of crosslinked polypropylene acid resin, crosslinked polypropylene acid resin and hydroxyethyl-cellulose combination is handed over or connection polyacrylic resin and the composite water soluble polymer gel of hydroxypropyl cellulose combination.
5. flushing free anemia of pregnant woman perineum medical treatment and nursing gel according to claim 1 is characterized in that: described chelating agen is one or both mixture in citric acid, sodium citrate, potassium citrate, calcium citrate, tartaric acid, sodium tartrate, Soluble tartar., Calcium d-tartrate, triethyl sodium ethylene diamine tetracetate, triethyl ethylenediamine tetraacetic acid (EDTA) potassium, triethyl ethylenediamine tetraacetic acid (EDTA) calcium, sodium gluconate, Fructus Vitis viniferae acid potassium, the calcium gluconate.
6. flushing free anemia of pregnant woman perineum medical treatment and nursing gel according to claim 1, it is characterized in that: described emollient is one or more mixture in glycerol, vitamin A, vitamin C, vitamin E, lanoline, the lactic acid.
7. according to the preparation method of the described flushing free anemia of pregnant woman of one of claim 1-6 perineum medical treatment and nursing gel, it is characterized in that comprising the steps:
A) natural organic bactericide of ASAP and emollient are dissolved in the part distilled water, left standstill 1-15 hour;
B) the water soluble polymer gel rubber material is dissolved in the part distilled water, makes solution;
C) water-soluble chitosan, aloe extract and chelating agen are dissolved in the part distilled water, make solution;
D) triethanolamine is dissolved in the part distilled water, makes solution;
E) with the mixed solution that makes in the step a), under agitation, after adding the water soluble polymer gel rubber material solution that makes in the step b), continue to stir 5-30 minute, supply the residue distilled water, and under stirring, add water-soluble chitosan, aloe extract and the chelating agent solution that makes in the step c);
F) with e) solution that makes, under stirring, add in the step d) and make triethanolamine solution, make gel.
8. preparation method according to claim 7 is characterized in that: also comprise step g), g) gel that makes is made finished product, adopt the disinfection with high pressure steam sterilization, the aseptic level gel that makes.
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| CN103405348A (en) * | 2013-07-31 | 2013-11-27 | 刘劲松 | Skin moisturizing lotion |
| CN104042791A (en) * | 2014-07-07 | 2014-09-17 | 江苏瑞京科技发展有限公司 | Antibacterial modified chitosan foaming agent and preparation method thereof |
| CN108014054A (en) * | 2018-02-02 | 2018-05-11 | 上海哈美实业发展有限公司 | A kind of temperature sensitive active compacts peptide and preparation method thereof |
| CN108186546A (en) * | 2018-02-02 | 2018-06-22 | 上海哈美实业发展有限公司 | A kind of private parts lotion and preparation method thereof |
| CN108403520A (en) * | 2018-05-07 | 2018-08-17 | 青岛高新区尚达医药研究所 | A kind of chitosan Mrs Chinese herbal medicine conditioning liquid and its application |
| CN108578313A (en) * | 2018-05-04 | 2018-09-28 | 四川生命源健康管理有限公司 | A kind of nursing for preventing private parts from blacking frost |
| CN109875936A (en) * | 2017-12-06 | 2019-06-14 | 河北得迪投资有限公司 | A kind of aloe nursing bacteriostatic gel and preparation method thereof |
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| CN103405348A (en) * | 2013-07-31 | 2013-11-27 | 刘劲松 | Skin moisturizing lotion |
| CN104042791A (en) * | 2014-07-07 | 2014-09-17 | 江苏瑞京科技发展有限公司 | Antibacterial modified chitosan foaming agent and preparation method thereof |
| CN104042791B (en) * | 2014-07-07 | 2017-06-27 | 江苏瑞京科技发展有限公司 | A kind of antibacterial modified chitose foaming agent and preparation method thereof |
| CN109875936A (en) * | 2017-12-06 | 2019-06-14 | 河北得迪投资有限公司 | A kind of aloe nursing bacteriostatic gel and preparation method thereof |
| CN108014054A (en) * | 2018-02-02 | 2018-05-11 | 上海哈美实业发展有限公司 | A kind of temperature sensitive active compacts peptide and preparation method thereof |
| CN108186546A (en) * | 2018-02-02 | 2018-06-22 | 上海哈美实业发展有限公司 | A kind of private parts lotion and preparation method thereof |
| CN108578313A (en) * | 2018-05-04 | 2018-09-28 | 四川生命源健康管理有限公司 | A kind of nursing for preventing private parts from blacking frost |
| CN108403520A (en) * | 2018-05-07 | 2018-08-17 | 青岛高新区尚达医药研究所 | A kind of chitosan Mrs Chinese herbal medicine conditioning liquid and its application |
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|---|---|
| CN102113981B (en) | 2012-02-08 |
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