CN102085253A - Compound green vitriol capsule - Google Patents

Abstract

The invention discloses a compound green vitriol capsule, which is prepared through the following steps by using green vitriol, american ginseng, hippocampus, cinnamon, jujube without kernel, and walnut kernel as raw drugs: properly extracting the raw drugs, adding auxiliary materials, stirring uniformly, and filling into a capsule shell. The drug has the effects of warming kidney and strengthening marrow, supplementing qi and nourishing yin, promoting blood generation and stopping blood losing, is convenient for taking and carrying, and is more favorable to quality control and shelf life extension.

Description

A kind of compound recipe Melanteritum capsule

Technical field

The present invention relates to the pharmaceutical preparations technology field, especially a kind of compound recipe Melanteritum capsule.

Background technology

FUFANG ZAOFAN WAN is the prescribed preparation that records in one one of Pharmacopoeia of People's Republic of China version in 2005, has the effect of the strong marrow of the kidney warming, supplementing QI and nourishing YIN, hemopoietic hemostasis.With Melanteritum, Radix Panacis Quinquefolii, Hippocampus, Cortex Cinnamomi, Fructus Jujubae (pitted), Semen Juglandis is raw material, will directly beat powder after each raw medicinal material drying, add refined honey and make small honey pill.

But, on the one hand, owing to the concrete ratio that discloses in the pharmacopeia between each crude drug of this medicine; And the curative effect of Chinese medicine composition is by accurate reasonably combined realization the between the different material medicine, and therefore, material rate uncertain also makes product quality and curative effect become wayward; On the other hand, the crude drug that does not add extraction directly is used as medicine, and easily breed bacteria is unfavorable for quality guarantee, and its shelf-life is shorter usually; In addition, the dose of small honey pill is bigger usually, takes inconvenience.

Summary of the invention

Purpose of the present invention just provides a kind of compound recipe Melanteritum capsule, and this medicine has the strong marrow of the kidney warming, supplementing QI and nourishing YIN, the effect of hemopoietic hemostatic, and its drug effect is reliable, and is quality controllable, and takes and carry all more convenient, helps quality control and extends the shelf life.

In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:

A kind of compound recipe Melanteritum capsule, with following amount amount part proportion raw material medicine:

Melanteritum 8-10 part, Radix Panacis Quinquefolii 5-6 part, hippocampus 3-4 part, Cortex Cinnamomi 3-4 part, Fructus Jujubae (pitted) 6-8 part, Semen Juglandis 8-10 part,

Make according to the method that comprises the steps:

(1), extract crude drug: get each crude drug of described proportioning, add the ethanol that 8-10 doubly measures 80-90%, reflux, extract, 2-3 time, each 3-4 hour, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 8-10 doubly to be measured, and decoction is extracted 2-3 time, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;

(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, it is an amount of to add pharmaceutic adjuvant, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Compared with prior art, the invention has the beneficial effects as follows: medicaments compound Melanteritum capsule of the present invention has filtered out suitable crude drug proportion by a large amount of contrast tests; Make it to have the strong marrow of significant the kidney warming, supplementing QI and nourishing YIN, the effect of hemopoietic hemostatic, and extracts of bulk drugs is made capsule by suitable extracting method, it takes and carries all more convenient, and can obviously reduce dose, the common high-temperature sterilization treatment of leaching process also more helps quality control and extends the shelf life.

The specific embodiment

The present invention is described in further detail below in conjunction with the specific embodiment.

Embodiment 1

Present embodiment compound recipe Melanteritum capsule is with following amount amount part proportion raw material medicine:

10 parts of Melanteritum, 6 parts of Radix Panacis Quinquefoliis, 4 parts of Hippocampus, 3 parts of Cortex Cinnamomis, 6 parts of Fructus Jujubae (pitted), 8 parts of Semen Juglandis make according to the method that comprises the steps:

(1), extract crude drug: get each crude drug of described proportioning, add the ethanol of 10 times of amounts 80%, reflux, extract, 3 times, each 3 hours, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 10 times of amounts, and decoction is extracted 2 times, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;

(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, add appropriate amount of starch, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Embodiment 2

Present embodiment compound recipe Melanteritum capsule is with following amount amount part proportion raw material medicine:

8 parts of Melanteritum, 5 parts of Radix Panacis Quinquefoliis, hippocampus 3 part, 4 parts of Cortex Cinnamomis, 8 parts of Fructus Jujubae (pitted), 8 parts of Semen Juglandis make according to the method that comprises the steps:

(1), extract crude drug: get each crude drug of described proportioning, add the ethanol of 8 times of amounts 90%, reflux, extract, 2 times, each 4 hours, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 8 times of amounts, and decoction is extracted 3 times, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;

(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, add an amount of dextrin, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.

Claims (1)

1. compound recipe Melanteritum capsule, with following amount amount part proportion raw material medicine:

Melanteritum 8-10 part, Radix Panacis Quinquefolii 5-6 part, hippocampus 3-4 part, Cortex Cinnamomi 3-4 part, Fructus Jujubae (pitted) 6-8 part, Semen Juglandis 8-10 part,

Make according to the method that comprises the steps:

(1), extract crude drug: get each crude drug of described proportioning, add the ethanol that 8-10 doubly measures 80-90%, reflux, extract, 2-3 time, each 3-4 hour, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 8-10 doubly to be measured, and decoction is extracted 2-3 time, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;

(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, it is an amount of to add pharmaceutic adjuvant, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.