CN102085253A - Compound green vitriol capsule - Google Patents
Compound green vitriol capsule Download PDFInfo
- Publication number
- CN102085253A CN102085253A CN2009102255818A CN200910225581A CN102085253A CN 102085253 A CN102085253 A CN 102085253A CN 2009102255818 A CN2009102255818 A CN 2009102255818A CN 200910225581 A CN200910225581 A CN 200910225581A CN 102085253 A CN102085253 A CN 102085253A
- Authority
- CN
- China
- Prior art keywords
- capsule
- extract
- melanteritum
- dry extract
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 20
- 150000001875 compounds Chemical class 0.000 title claims abstract description 10
- SURQXAFEQWPFPV-UHFFFAOYSA-L iron(2+) sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Fe+2].[O-]S([O-])(=O)=O SURQXAFEQWPFPV-UHFFFAOYSA-L 0.000 title abstract 3
- 229910000359 iron(II) sulfate Inorganic materials 0.000 title abstract 3
- 239000003814 drug Substances 0.000 claims abstract description 25
- 229940079593 drug Drugs 0.000 claims abstract description 15
- 210000001320 hippocampus Anatomy 0.000 claims abstract description 6
- 239000000284 extract Substances 0.000 claims description 21
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 238000001035 drying Methods 0.000 claims description 9
- 239000012141 concentrate Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 5
- 210000000582 semen Anatomy 0.000 claims description 5
- 238000002481 ethanol extraction Methods 0.000 claims description 4
- 238000012856 packing Methods 0.000 claims description 4
- 238000010298 pulverizing process Methods 0.000 claims description 4
- 238000010992 reflux Methods 0.000 claims description 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 210000003734 kidney Anatomy 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 4
- 230000001502 supplementing effect Effects 0.000 abstract description 4
- 238000010792 warming Methods 0.000 abstract description 4
- 238000003908 quality control method Methods 0.000 abstract description 3
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 244000223760 Cinnamomum zeylanicum Species 0.000 abstract 1
- 240000007049 Juglans regia Species 0.000 abstract 1
- 235000009496 Juglans regia Nutrition 0.000 abstract 1
- 240000005373 Panax quinquefolius Species 0.000 abstract 1
- 235000003140 Panax quinquefolius Nutrition 0.000 abstract 1
- 244000126002 Ziziphus vulgaris Species 0.000 abstract 1
- 235000017803 cinnamon Nutrition 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 238000005728 strengthening Methods 0.000 abstract 1
- 235000020234 walnut Nutrition 0.000 abstract 1
- 230000002607 hemopoietic effect Effects 0.000 description 3
- 235000012907 honey Nutrition 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 230000002439 hemostatic effect Effects 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- -1 and therefore Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a compound green vitriol capsule, which is prepared through the following steps by using green vitriol, american ginseng, hippocampus, cinnamon, jujube without kernel, and walnut kernel as raw drugs: properly extracting the raw drugs, adding auxiliary materials, stirring uniformly, and filling into a capsule shell. The drug has the effects of warming kidney and strengthening marrow, supplementing qi and nourishing yin, promoting blood generation and stopping blood losing, is convenient for taking and carrying, and is more favorable to quality control and shelf life extension.
Description
Technical field
The present invention relates to the pharmaceutical preparations technology field, especially a kind of compound recipe Melanteritum capsule.
Background technology
FUFANG ZAOFAN WAN is the prescribed preparation that records in one one of Pharmacopoeia of People's Republic of China version in 2005, has the effect of the strong marrow of the kidney warming, supplementing QI and nourishing YIN, hemopoietic hemostasis.With Melanteritum, Radix Panacis Quinquefolii, Hippocampus, Cortex Cinnamomi, Fructus Jujubae (pitted), Semen Juglandis is raw material, will directly beat powder after each raw medicinal material drying, add refined honey and make small honey pill.
But, on the one hand, owing to the concrete ratio that discloses in the pharmacopeia between each crude drug of this medicine; And the curative effect of Chinese medicine composition is by accurate reasonably combined realization the between the different material medicine, and therefore, material rate uncertain also makes product quality and curative effect become wayward; On the other hand, the crude drug that does not add extraction directly is used as medicine, and easily breed bacteria is unfavorable for quality guarantee, and its shelf-life is shorter usually; In addition, the dose of small honey pill is bigger usually, takes inconvenience.
Summary of the invention
Purpose of the present invention just provides a kind of compound recipe Melanteritum capsule, and this medicine has the strong marrow of the kidney warming, supplementing QI and nourishing YIN, the effect of hemopoietic hemostatic, and its drug effect is reliable, and is quality controllable, and takes and carry all more convenient, helps quality control and extends the shelf life.
In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:
A kind of compound recipe Melanteritum capsule, with following amount amount part proportion raw material medicine:
Melanteritum 8-10 part, Radix Panacis Quinquefolii 5-6 part, hippocampus 3-4 part, Cortex Cinnamomi 3-4 part, Fructus Jujubae (pitted) 6-8 part, Semen Juglandis 8-10 part,
Make according to the method that comprises the steps:
(1), extract crude drug: get each crude drug of described proportioning, add the ethanol that 8-10 doubly measures 80-90%, reflux, extract, 2-3 time, each 3-4 hour, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 8-10 doubly to be measured, and decoction is extracted 2-3 time, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;
(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, it is an amount of to add pharmaceutic adjuvant, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.
Compared with prior art, the invention has the beneficial effects as follows: medicaments compound Melanteritum capsule of the present invention has filtered out suitable crude drug proportion by a large amount of contrast tests; Make it to have the strong marrow of significant the kidney warming, supplementing QI and nourishing YIN, the effect of hemopoietic hemostatic, and extracts of bulk drugs is made capsule by suitable extracting method, it takes and carries all more convenient, and can obviously reduce dose, the common high-temperature sterilization treatment of leaching process also more helps quality control and extends the shelf life.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Embodiment 1
Present embodiment compound recipe Melanteritum capsule is with following amount amount part proportion raw material medicine:
10 parts of Melanteritum, 6 parts of Radix Panacis Quinquefoliis, 4 parts of Hippocampus, 3 parts of Cortex Cinnamomis, 6 parts of Fructus Jujubae (pitted), 8 parts of Semen Juglandis make according to the method that comprises the steps:
(1), extract crude drug: get each crude drug of described proportioning, add the ethanol of 10 times of amounts 80%, reflux, extract, 3 times, each 3 hours, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 10 times of amounts, and decoction is extracted 2 times, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;
(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, add appropriate amount of starch, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.
Embodiment 2
Present embodiment compound recipe Melanteritum capsule is with following amount amount part proportion raw material medicine:
8 parts of Melanteritum, 5 parts of Radix Panacis Quinquefoliis, hippocampus 3 part, 4 parts of Cortex Cinnamomis, 8 parts of Fructus Jujubae (pitted), 8 parts of Semen Juglandis make according to the method that comprises the steps:
(1), extract crude drug: get each crude drug of described proportioning, add the ethanol of 8 times of amounts 90%, reflux, extract, 2 times, each 4 hours, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 8 times of amounts, and decoction is extracted 3 times, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;
(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, add an amount of dextrin, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.
Claims (1)
1. compound recipe Melanteritum capsule, with following amount amount part proportion raw material medicine:
Melanteritum 8-10 part, Radix Panacis Quinquefolii 5-6 part, hippocampus 3-4 part, Cortex Cinnamomi 3-4 part, Fructus Jujubae (pitted) 6-8 part, Semen Juglandis 8-10 part,
Make according to the method that comprises the steps:
(1), extract crude drug: get each crude drug of described proportioning, add the ethanol that 8-10 doubly measures 80-90%, reflux, extract, 2-3 time, each 3-4 hour, merge each time extracting solution, reclaim ethanol, concentrate, drying, pulverizing gets dry extract 1; Residue behind the ethanol extraction adds 8-10 doubly to be measured, and decoction is extracted 2-3 time, merges decoction liquor, concentrates, and drying is pulverized, and gets dry extract 2;
(2), make capsule: the dry extract 1 and 2 that combining step (1) makes, it is an amount of to add pharmaceutic adjuvant, mix homogeneously is granulated, and divides in the capsule shells of packing into, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102255818A CN102085253A (en) | 2009-12-03 | 2009-12-03 | Compound green vitriol capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102255818A CN102085253A (en) | 2009-12-03 | 2009-12-03 | Compound green vitriol capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102085253A true CN102085253A (en) | 2011-06-08 |
Family
ID=44097414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102255818A Pending CN102085253A (en) | 2009-12-03 | 2009-12-03 | Compound green vitriol capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102085253A (en) |
-
2009
- 2009-12-03 CN CN2009102255818A patent/CN102085253A/en active Pending
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| Date | Code | Title | Description |
|---|---|---|---|
| DD01 | Delivery of document by public notice |
Addressee: Liu Xin Document name: Notification of Passing Preliminary Examination of the Application for Invention |
|
| C06 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Liu Xin Document name: Notification of Publication of the Application for Invention |
|
| DD01 | Delivery of document by public notice |
Addressee: Liu Xin Document name: Notification of before Expiration of Request of Examination as to Substance |
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| DD01 | Delivery of document by public notice |
Addressee: Liu Xin Document name: Notification that Application Deemed to be Withdrawn |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110608 |