CN100374130C - Stasis expelling vessel freeing drip pill - Google Patents
Stasis expelling vessel freeing drip pill Download PDFInfo
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- CN100374130C CN100374130C CNB200510127400XA CN200510127400A CN100374130C CN 100374130 C CN100374130 C CN 100374130C CN B200510127400X A CNB200510127400X A CN B200510127400XA CN 200510127400 A CN200510127400 A CN 200510127400A CN 100374130 C CN100374130 C CN 100374130C
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Abstract
The present invention discloses a stasis expelling vessel freeing drip pill which belongs to traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases. The present invention has the advantages of effectively improved medical bioavailability, reliable curative effect, thorough treatment, fast absorption and convenient application. The present invention is characterized in that leeches, gadflies, peach kernels and rhubarb are used as a recipe, are respectively pulverized, and are mixed in a progressive increase method; after the materials are soaked by water, ultrasonic extraction is carried out; after ethanol is used for further ultrasonic treatment on filter residues, twice filter liquor is merged; afterwards, medicine powder is obtained through concentrating, drying and pulverizing; polyethylene glycol-6000 water solution solid substrate is uniformly mixed with the medicine powder to be made into the drip poll with the ratio of medicine to substrate of 1/2.4.
Description
Technical field
The present invention relates to a kind of pure Chinese medicinal preparation, in particular for treating the Chinese medicine prescription of the cardio-cerebralvascular diseases that causes by high viscous disease.
Background technology
" stasis expelling vessel freeing drip pill " existing capsule belongs to exclusive patented product of my company and Chinese medicine protection kind at present.For above-mentioned disease special efficacy is arranged all, but exist weakness such as big, the difficult absorption of taking dose, storage and transportation inconvenience.
Summary of the invention
Have deficiencies such as dosage is big, the slow bioavailability of absorption is low for overcoming above-mentioned dosage form, the objective of the invention is to provide a kind of stasis expelling vessel freeing drip pill, it can improve bioavailability of medicament effectively, absorbs fast, taking convenience, more remarkable treatment effect.
The technical solution adopted for the present invention to solve the technical problems is: with the prescription of following traditional Chinese medicines as this medicine.
Hirudo 500g Tabanus 20g
Semen Persicae 41.7g Radix Et Rhizoma Rhei 106.7g
The present invention adopts Polyethylene Glycol---6000 water solublity solid state substrates.
Technology: the Hirudo, Tabanus, Semen Persicae, Radix Et Rhizoma Rhei four Chinese medicine of getting recipe quantity are pulverized, and press incremental method and mix, and add 5 times water, soaked 24 hours, and in 40 ℃ of supersound extraction 20 minutes, filtration; Filtering residue, filters in 40 ℃ of supersound process 20 minutes with 70% ethanol, reclaims ethanol.Twice filtrate is merged, concentrates in 70 ℃ with the economic benefits and social benefits concentrator, extractum, drying is pulverized with pulverizer, must medicated powder.Press medicine and substrate than 1: 2.4 mixing, control material temperature is in 90 ℃, and 70 ℃ of condensation temperatures to drip apart from 2.0 centimetres, are dripped 12 droplets/minute of speed, and liquid coolant is that liquid paraffin is a coolant, adopt drop pill machine-processed 1000 of 30 milligrams/ball drop pill.
Beneficial effect
The stasis expelling vessel freeing drip pill prescription is based on theory of Chinese medical science, with reference to ancient prescription " keeping out it " Fang Yi, best prescription has been found out in repetition test and clinical practice surplus ten year, adopting modern preparation technique. its innovation part is to utilize solid dispersions technique to prepare drop pill, reach modernization of Chinese medicine level, improve drug bioavailability, reduce drug dose, created a novel form that curative effect is outstanding, make this product curative effect more reliable, treat more thoroughly, can reach treating both the principal and secondary aspects of a disease, filled up the blank of stasis expelling vessel freeing drip pill dosage form.
The specific embodiment
The concrete mode of the present invention is identical with technical scheme, and this repeats no more.Prescription is 1000 amounts.Usage and dosage: oral, a 2-4 grain, an order 3 times.
Claims (1)
1. a Chinese medicine stasis expelling vessel freeing drip pill that is used for the treatment of cardiovascular and cerebrovascular disease is characterized in that adopting polyethylene glycol 6000 water solublity solid state substrate; Water intaking trematodiasis 500g, Tabanus 20g, Semen Persicae 41.7g, Radix Et Rhizoma Rhei 106.7g pulverize, and press incremental method and mix, and add 5 times water, soaked 24 hours, and in 40 ℃ of supersound process 20 minutes, filtration; Filtering residue concentrates with 70% ethanol, gets extractum, and drying is ground into medicated powder; Press 1: 2.4 mixing of Chinese medicine dry extract medicated powder and substrate, control material temperature is in 90 ℃, and 70 ℃ of condensation temperatures with 2.0 centimetres of distances, are dripped 12 droplets/minute of speed, and liquid paraffin is a coolant, adopts machine-processed 1000 of the 30 milligrams/ball drop pill that get of drop pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200510127400XA CN100374130C (en) | 2005-12-28 | 2005-12-28 | Stasis expelling vessel freeing drip pill |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200510127400XA CN100374130C (en) | 2005-12-28 | 2005-12-28 | Stasis expelling vessel freeing drip pill |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1823952A CN1823952A (en) | 2006-08-30 |
| CN100374130C true CN100374130C (en) | 2008-03-12 |
Family
ID=36934892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB200510127400XA Active CN100374130C (en) | 2005-12-28 | 2005-12-28 | Stasis expelling vessel freeing drip pill |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100374130C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102225076B (en) * | 2011-06-14 | 2012-10-10 | 重庆时珍阁普生药业有限公司 | Modified Maixuekang preparation, modified Maixuekang enteric-coated preparation as well as preparation methods and applications thereof |
| CN103505532B (en) * | 2013-10-10 | 2015-02-25 | 北京康远制药有限公司 | Traditional Chinese medicinal granules capable of removing blood stasis and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051019C (en) * | 1997-09-18 | 2000-04-05 | 鹤岗圣尔药业有限公司 | Capsule for removing blood stasis and activating blood flow |
| CN1506097A (en) * | 2002-12-10 | 2004-06-23 | 浙江得恩德制药有限公司 | Chinese medicine capsule for treating ischemic cerebral apoplexy |
-
2005
- 2005-12-28 CN CNB200510127400XA patent/CN100374130C/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051019C (en) * | 1997-09-18 | 2000-04-05 | 鹤岗圣尔药业有限公司 | Capsule for removing blood stasis and activating blood flow |
| CN1506097A (en) * | 2002-12-10 | 2004-06-23 | 浙江得恩德制药有限公司 | Chinese medicine capsule for treating ischemic cerebral apoplexy |
Non-Patent Citations (2)
| Title |
|---|
| 国家新药注册数据. 国家药品监督管理局药品注册司，药品审评中心，WS-094(Z-013)97，电子工业出版社. 2001 * |
| 逐瘀通脉滴丸药理药效学研究. 于敏等.黑龙江医药科学，第28卷第5期. 2005 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1823952A (en) | 2006-08-30 |
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