CN102085247A - Medicinal drop pills having effects of nourishing blood, eliminating blood stasis, soothing the liver and regulating menstruation - Google Patents
Medicinal drop pills having effects of nourishing blood, eliminating blood stasis, soothing the liver and regulating menstruation Download PDFInfo
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- CN102085247A CN102085247A CN200910225570XA CN200910225570A CN102085247A CN 102085247 A CN102085247 A CN 102085247A CN 200910225570X A CN200910225570X A CN 200910225570XA CN 200910225570 A CN200910225570 A CN 200910225570A CN 102085247 A CN102085247 A CN 102085247A
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Abstract
The invention discloses medicinal drop pills having effects of nourishing blood, eliminating blood stasis, soothing the liver and regulating menstruation. The medicinal drop pills are prepared by the following steps of: extracting motherwort, angelica, white peony root, bupleurum root, costustoot and Szechuan lovage rhizome serving as raw materials, adding polyethylene glycol 4000, mixing uniformly and dropping. The medicinal drop pills can increase the concentration of active ingredients, so that the pills act faster effect, have exact efficacy and high safety, and can be administered in small dose; in addition, by high-temperature extraction, the medicinal drop pills effectively achieve a sterilization effect, which contributes to the quality control of preparation and the improvement of the quality of medicaments.
Description
Technical field
The present invention relates to the pharmaceutical preparations technology field, especially a kind of medicinal dropping ball with the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia.
Background technology
Must give birth to ball and be the prescribed preparation that records in one one of Pharmacopoeia of People's Republic of China version in 2005, have the effect of the blood stasis dispelling of nourishing blood, soothing the liver regulating menstruation; The menoxenia, the dysmenorrhea that are used for caused by energy stagnation and blood stasis, card sees the rare clot of menstrual blood volume, delayed menstrual period or front and back are indefinite, through row lower abdominal distention pain, Huo You mass in the abdomen mass in the abdomen.With Herba Leonuri, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Bupleuri, the Radix Aucklandiae, Rhizoma Chuanxiong is crude drug, directly is ground into fine powder, adds refined honey behind the mixing that sieves and makes big honeyed pills.Because the restriction of its preparation method is not carried out any extraction to raw medicinal material, thereby may be had a large amount of antibacterials and other impurity, be unfavorable for quality control, and onset is slower.
Summary of the invention
Purpose of the present invention just provides a kind of medicinal dropping ball with the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia, and this drug effect is very fast, determined curative effect, safety is good, dose is little, and is beneficial to quality control.
In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:
A kind of medicinal dropping ball with the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia is a crude drug for 1 part with 12 parts of Herba Leonuris, 4 parts of Radix Angelicae Sinensis, 4 parts of the Radix Paeoniae Albas, 2 parts of Radix Bupleuri, 1 part of the Radix Aucklandiae, Rhizoma Chuanxiong, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 2-3 time, and each amount of water is 8-10 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: (1.5～1.8), the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, get final product.
During above-mentioned steps (2) preparation medicinal liquid, extract: the Macrogol 4000 weight ratio was excellent with 1: 1.6.
When above-mentioned steps (3) was dripped the system drop pill, dripping speed was excellent with 45～50/minute, and coolant is excellent with liquid paraffin.
Compared with prior art, the invention has the beneficial effects as follows:
Medicinal dropping ball of the present invention extracts raw medicinal material by suitable method, makes drop pill after adding suitable pharmaceutic adjuvant then, can improve the concentration of active component, makes that onset is faster, dose is littler, determined curative effect, safety be good; And, by high temperature extraction, can effectively reach sterilization effect, help the quality control of preparation, improve drug quality; In addition, make drop pill, take and carry etc. all more convenient than traditional pill.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Following each embodiment has the medicinal dropping ball of the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia, is that crude drug makes for 1 part with 12 parts of Herba Leonuris, 4 parts of Radix Angelicae Sinensis, 4 parts of the Radix Paeoniae Albas, 2 parts of Radix Bupleuri, 1 part of the Radix Aucklandiae, Rhizoma Chuanxiong all.
Embodiment 1
Present embodiment has the medicinal dropping ball of the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 2 times, and each amount of water is 10 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: 1.5, the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, dripping speed is 50/minute, and coolant is a liquid paraffin.
Embodiment 2
Present embodiment has the medicinal dropping ball of the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 3 times, and each amount of water is 9 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: 1.6, the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, dripping speed is 45/minute, and coolant is a liquid paraffin.
Embodiment 3
Present embodiment has the medicinal dropping ball of the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 3 times, and each amount of water is 8 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: 1.8, the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, dripping speed is 48/minute, and coolant is a liquid paraffin.
Claims (3)
1. the medicinal dropping ball with the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia is a crude drug for 1 part with 12 parts of Herba Leonuris, 4 parts of Radix Angelicae Sinensis, 4 parts of the Radix Paeoniae Albas, 2 parts of Radix Bupleuri, 1 part of the Radix Aucklandiae, Rhizoma Chuanxiong, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 2-3 time, and each amount of water is 8-10 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: (1.5～1.8), the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, get final product.
2. the medicinal dropping ball with the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia according to claim 1 is characterized in that: during described step (2) preparation medicinal liquid, extract: the Macrogol 4000 weight ratio is 1: 1.6.
3. the medicinal dropping ball with the blood stasis dispelling of nourishing blood, soothing the liver regulating menoxenia according to claim 1 is characterized in that: when described step (3) was dripped the system drop pill, dripping speed was 45～50/minute, and coolant is a liquid paraffin.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200910225570XA CN102085247A (en) | 2009-12-03 | 2009-12-03 | Medicinal drop pills having effects of nourishing blood, eliminating blood stasis, soothing the liver and regulating menstruation |
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| CN200910225570XA CN102085247A (en) | 2009-12-03 | 2009-12-03 | Medicinal drop pills having effects of nourishing blood, eliminating blood stasis, soothing the liver and regulating menstruation |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526229A (en) * | 2011-12-27 | 2012-07-04 | 陕西兴邦药业有限公司 | Chinese medicinal composition for regulating menstruation, nourishing blood, regulating flow of qi and dissipating blood stasis and preparation method thereof |
| CN102641361A (en) * | 2012-02-21 | 2012-08-22 | 常熟市方塔涂料化工有限公司 | Chinese herb preparation for treating abnormal menstruation |
| CN102670774A (en) * | 2012-05-17 | 2012-09-19 | 王宏彬 | Traditional Chinese medicine pill for treating puerperal disease |
| CN102784207A (en) * | 2012-08-01 | 2012-11-21 | 李虹霖 | Desheng dropping pill and preparation method thereof |
| CN103127352A (en) * | 2013-03-05 | 2013-06-05 | 李桂娟 | Chinese medicine composition for treating blood stasis type irregular menstruation |
-
2009
- 2009-12-03 CN CN200910225570XA patent/CN102085247A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526229A (en) * | 2011-12-27 | 2012-07-04 | 陕西兴邦药业有限公司 | Chinese medicinal composition for regulating menstruation, nourishing blood, regulating flow of qi and dissipating blood stasis and preparation method thereof |
| CN102526229B (en) * | 2011-12-27 | 2013-08-07 | 陕西兴邦药业有限公司 | Chinese medicinal composition for regulating menstruation, nourishing blood, regulating flow of qi and dissipating blood stasis and preparation method thereof |
| CN102641361A (en) * | 2012-02-21 | 2012-08-22 | 常熟市方塔涂料化工有限公司 | Chinese herb preparation for treating abnormal menstruation |
| CN102641361B (en) * | 2012-02-21 | 2014-02-26 | 常熟华港制药有限公司 | Chinese herb preparation for treating abnormal menstruation |
| CN102670774A (en) * | 2012-05-17 | 2012-09-19 | 王宏彬 | Traditional Chinese medicine pill for treating puerperal disease |
| CN102784207A (en) * | 2012-08-01 | 2012-11-21 | 李虹霖 | Desheng dropping pill and preparation method thereof |
| CN103127352A (en) * | 2013-03-05 | 2013-06-05 | 李桂娟 | Chinese medicine composition for treating blood stasis type irregular menstruation |
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Application publication date: 20110608 |