CN102085275A - Medicinal lozenge for clearing throat and preparation method thereof - Google Patents
Medicinal lozenge for clearing throat and preparation method thereof Download PDFInfo
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- CN102085275A CN102085275A CN2009102255714A CN200910225571A CN102085275A CN 102085275 A CN102085275 A CN 102085275A CN 2009102255714 A CN2009102255714 A CN 2009102255714A CN 200910225571 A CN200910225571 A CN 200910225571A CN 102085275 A CN102085275 A CN 102085275A
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Abstract
The invention discloses a medicinal lozenge for clearing throat and a preparation method thereof. The lozenge is prepared by employing immature fruits of Terninalia chebula, balloonflower roots, boat-fruited sterculia seeds, exocarpium citri rubrum, fructus aurantii, mulberry leaves and menthols as raw materials, extracting extracts from the raw materials and adding proper pharmaceutical adjuvants. The medicinal lozenge of the invention has remarkable and fast effects of clearing throat by directly taking effect on pains; moreover no toxic and side effects occur.
Description
Technical field
The present invention relates to the pharmaceutical preparations technology field, especially a kind of medicine buccal tablet and preparation method thereof with throat-benefiting effect.
Background technology
Affection due to external wind and heat, acute/chronic pharyngitis, tonsillitis etc. all can cause card marquis such as pharyngeal dryness, hoarseness, and the medicine of some concrete throat-benefiting commonly used clinically and/or the chest stuffiness relieving throat moistening function is treated, as qinghouyan mixture, throat-benefiting granule, good for larynx pill etc.; But it is all very not convenient to take and carry etc. as qinghouyan mixture and throat-benefiting granule etc., and good for larynx pill etc. contain directly usually with crude drug beats that powder (un-extracted processing) is used as medicine etc. and to the harmful effects of quality control and shelf-life etc.; Usually, this class patient more is ready to accept safe and effective and takes and medicine easy to carry, as with the combination of suitable crude drug, after suitably extracting, make buccal tablet, can reach effectively and onset rapidly, purposes such as the patient part that goes directly, and take and carry all comparatively convenient.Determine that suitable crude drug combination and compatibility then is crucial, different material combination, the extract that different extracting method obtains will be made buccal tablet, also needs just may obtain good arduous effect in conjunction with suitable pharmaceutic adjuvant.
Summary of the invention
Purpose of the present invention just provides a kind of medicine buccal tablet with throat-benefiting effect, and this medicine buccal tablet has good throat-benefiting effect, directly acts on the affected part, and is rapid-action; And have no side effect.
In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:
A kind of medicine buccal tablet with throat-benefiting effect, with FRUCTUS TERMINALIAE IMMATURUS, Radix Platycodonis, Semen Sterculiae Lychnophorae, dried tangerine peel, Lignum Aquilariae Resinatum, Fructus Aurantii, Folium Mori, Folium Perillae, Mentholum is that crude drug makes, the weight portion proportioning of each crude drug is:
FRUCTUS TERMINALIAE IMMATURUS 12-15 part, Radix Platycodonis 8-10 part, Semen Sterculiae Lychnophorae 8-10 part, tangerine 6-8 part, Lignum Aquilariae Resinatum 3-5 part, Fructus Aurantii 6-8 part, Folium Mori 3-4 part, Folium Perillae 4-6 part, Mentholum 2-3 part.
The preparation method of said medicine buccal tablet comprises following key step:
(1), extract raw medicinal material: get dried tangerine peel, Lignum Aquilariae Resinatum and the Folium Perillae of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; Medical material residue behind the extraction volatile oil is mixed with other each raw medicinal material of described proportioning, decoct with water and extract 2-3 time, each amount of water is 10-12 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), the preparation buccal tablet: according to extract: the mannitol weight ratio is 1: (0.2～0.3), with the extract and an amount of mannitol mix homogeneously that step (1) obtains, spray again and add the volatile oil that step (1) obtains, mix homogeneously, granulate, repress is made tablet, promptly gets described medicine buccal tablet.
Compared with prior art, the invention has the beneficial effects as follows:
Medicine buccal tablet of the present invention is by reasonable raw material medicine matched combined, combined effect has good throat-benefiting effect, can be used for pharyngeal dryness, hoarseness due to the affection due to external wind and heat, and acute/chronic pharyngitis, tonsillitis etc. see above-mentioned card marquis person, also can often do in order to the protection vocal cords; Make buccal tablet, taking convenience not only, and can directly act on the affected part, onset is very fast; In addition, raw materials used medical material is the Chinese medicine commonly used of safe without toxic side effect, and confirms that through animal experiment this medicine buccal tablet has no side effect, and is safe and reliable.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Following each embodiment has the medicine buccal tablet of throat-benefiting effect, is that crude drug makes for 1 part with 12 parts of Herba Leonuris, 4 parts of Radix Angelicae Sinensis, 4 parts of the Radix Paeoniae Albas, 2 parts of Radix Bupleuri, 1 part of the Radix Aucklandiae, Rhizoma Chuanxiong all.
Embodiment 1
Present embodiment has the medicine buccal tablet of throat-benefiting effect, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 2 times, and each amount of water is 10 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: 1.5, the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system buccal tablet: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made buccal tablet, dripping speed is 50/minute, and coolant is a liquid paraffin.
Embodiment 2
Present embodiment has the medicine buccal tablet of throat-benefiting effect, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 3 times, and each amount of water is 9 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: 1.6, the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system buccal tablet: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made buccal tablet, dripping speed is 45/minute, and coolant is a liquid paraffin.
Embodiment 3
Present embodiment has the medicine buccal tablet of throat-benefiting effect, makes according to the method that comprises the steps:
(1), extract raw medicinal material: get Radix Angelicae Sinensis, the Radix Aucklandiae and the Rhizoma Chuanxiong of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; The medical material residue mixes with other each raw medicinal material of getting described proportioning, decocts with water to extract 3 times, and each amount of water is 8 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), preparation medicinal liquid: according to extract: the Macrogol 4000 weight ratio is 1: 1.8, the Macrogol 4000 of described proportioning slowly is heated to molten condition, slowly add the extract that step (1) obtains, mix homogeneously, add the volatile oil that step (1) obtains again, mix homogeneously makes medicinal liquid, 70 ± 2 ℃ of insulations, standby;
(3), drip the system buccal tablet: under 70 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made buccal tablet, dripping speed is 48/minute, and coolant is a liquid paraffin.
Claims (2)
1. medicine buccal tablet with throat-benefiting effect, with FRUCTUS TERMINALIAE IMMATURUS, Radix Platycodonis, Semen Sterculiae Lychnophorae, dried tangerine peel, Lignum Aquilariae Resinatum, Fructus Aurantii, Folium Mori, Folium Perillae, Mentholum is that crude drug makes, the weight portion proportioning of each crude drug is:
FRUCTUS TERMINALIAE IMMATURUS 12-15 part, Radix Platycodonis 8-10 part, Semen Sterculiae Lychnophorae 8-10 part, tangerine 6-8 part, Lignum Aquilariae Resinatum 3-5 part, Fructus Aurantii 6-8 part, Folium Mori 3-4 part, Folium Perillae 4-6 part, Mentholum 2-3 part.
2. the preparation method of the described medicine buccal tablet of claim 1 comprises following key step:
(1), extract raw medicinal material: get dried tangerine peel, Lignum Aquilariae Resinatum and the Folium Perillae of described proportioning, be ground into coarse powder, steam distillation extracts volatile oil, and the device preservation is standby in addition with volatile oil; Medical material residue behind the extraction volatile oil is mixed with other each raw medicinal material of described proportioning, decoct with water and extract 2-3 time, each amount of water is 10-12 times, and merge extractive liquid, concentrates, drying, and it is standby to make extract;
(2), the preparation buccal tablet: according to extract: the mannitol weight ratio is 1: (0.2～0.3), with the extract and an amount of mannitol mix homogeneously that step (1) obtains, spray again and add the volatile oil that step (1) obtains, mix homogeneously, granulate, repress is made tablet, promptly gets described medicine buccal tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102255714A CN102085275A (en) | 2009-12-03 | 2009-12-03 | Medicinal lozenge for clearing throat and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102255714A CN102085275A (en) | 2009-12-03 | 2009-12-03 | Medicinal lozenge for clearing throat and preparation method thereof |
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| Publication Number | Publication Date |
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| CN102085275A true CN102085275A (en) | 2011-06-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2009102255714A Pending CN102085275A (en) | 2009-12-03 | 2009-12-03 | Medicinal lozenge for clearing throat and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102726585A (en) * | 2012-05-29 | 2012-10-17 | 桂龙药业(安徽)有限公司 | Throat-clearing health food and preparation method thereof |
| CN102771853A (en) * | 2012-05-09 | 2012-11-14 | 操应胜 | Peucedanum praeruptorum dunn beverage, peucedanum praeruptorum dunn beverage health-care product and production process thereof |
| CN103520332A (en) * | 2013-10-24 | 2014-01-22 | 吴心怡 | Buccal tablet capable of clearing heat from pharynx and throat and performing anti-inflammation and throat protection and preparation method thereof |
| CN104738285A (en) * | 2013-12-26 | 2015-07-01 | 天津中新药业研究中心 | Throat clearing candy and preparation method thereof |
-
2009
- 2009-12-03 CN CN2009102255714A patent/CN102085275A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771853A (en) * | 2012-05-09 | 2012-11-14 | 操应胜 | Peucedanum praeruptorum dunn beverage, peucedanum praeruptorum dunn beverage health-care product and production process thereof |
| CN102726585A (en) * | 2012-05-29 | 2012-10-17 | 桂龙药业(安徽)有限公司 | Throat-clearing health food and preparation method thereof |
| CN103520332A (en) * | 2013-10-24 | 2014-01-22 | 吴心怡 | Buccal tablet capable of clearing heat from pharynx and throat and performing anti-inflammation and throat protection and preparation method thereof |
| CN104738285A (en) * | 2013-12-26 | 2015-07-01 | 天津中新药业研究中心 | Throat clearing candy and preparation method thereof |
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Application publication date: 20110608 |