CN102085254A - Codonopsis pilosula, radix astragali and kadsura longepedunculata dripping pill - Google Patents
Codonopsis pilosula, radix astragali and kadsura longepedunculata dripping pill Download PDFInfo
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- CN102085254A CN102085254A CN2009102527070A CN200910252707A CN102085254A CN 102085254 A CN102085254 A CN 102085254A CN 2009102527070 A CN2009102527070 A CN 2009102527070A CN 200910252707 A CN200910252707 A CN 200910252707A CN 102085254 A CN102085254 A CN 102085254A
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Abstract
The invention discloses a codonopsis pilosula, radix astragali and kadsura longepedunculata dripping pill which is prepared by using kadsura longepedunculata, codonopsis pilosula, radix astragali, fried spina date seeds as raw material medicines through the steps of extracting, adding polyethylene glycol 400 and polyethylene glycol 4000, uniformly mixing and dripping. The dripping pill has the effects of tonifying qi, strengthening the spleen, calming the heart and tranquilizing the mind, wherein active constituents have higher concentration, quick action and smaller dosage; the dripping pill is beneficial to the quality control of preparations and quality improvement of medicaments; and the operation flows can be simplified, and the production period is shortened.
Description
Technical field
The present invention relates to the pharmaceutical preparations technology field, especially a seed ginseng stilbene schisandra fruit dripping pill.
Background technology
SHENQI WUWEIZI PIAN is the prescribed preparation that records in one one of Pharmacopoeia of People's Republic of China version in 2005, effect with replenishing QI to invigorate the spleen, mind tranquilizing and the heart calming, be used for due to insufficiency of vital energy and blood, the deficiency of both the heart and spleen insomnia, dreaminess, forgetful, weak, cardiopalmus, breathe hard, spontaneous perspiration.With Fructus Schisandrae Sphenantherae, Radix Codonopsis, the Radix Astragali, Semen Ziziphi Spinosae (parched) is raw material, Radix Codonopsis and 1/3rd Fructus Schisandrae Sphenantherae medical material directly are ground into fine powder, the Radix Astragali, Semen Ziziphi Spinosae (parched), and remaining Fructus Schisandrae Sphenantherae make fluid extract with percolation extraction after 45%, 70%, 60% alcohol dipping respectively, mixing again, add granulate behind the suitable adjuvant, tabletting makes.
Because the restriction of its preparation method, part material medical material un-extracted be directly with medical material fine powder pelletizing press sheet, thereby may exist a large amount of antibacterials and other impurity, be unfavorable for quality control, and onset is slower; And the part medical material adopts the percolation extraction method, and solvent-oil ratio is big; And the different material medicine needs Different concentrations of alcohol dipping back percolation, complex operation, and the production cycle is longer.
Summary of the invention
Purpose of the present invention just provides a kind of ginseng stilbene schisandra fruit dripping pill, and this medicinal dropping ball has the effect of replenishing QI to invigorate the spleen, mind tranquilizing and the heart calming, and wherein active component concentration is higher, and onset is faster, dose is littler; And the quality control that helps preparation improves drug quality; Also the simplified operation flow process shortens the production cycle.
In order to realize the foregoing invention purpose, the technical solution used in the present invention is as follows:
One seed ginseng stilbene schisandra fruit dripping pill, with following amount amount part proportion raw material medicine:
6 parts of Fructus Schisandrae Sphenantheraes, 2 parts of Radix Codonopsis, 4 parts of the Radixs Astragali, 1 part of Semen Ziziphi Spinosae (parched),
Make according to the method that comprises the steps:
(1), extract raw medicinal material: get each crude drug of described proportioning, mix, add 60-75% alcohol reflux 2-3 time, merge extractive liquid,, recovery ethanol, reconcentration is dried to dry extract, makes extract;
(2), preparation medicinal liquid: according to extract: PEG400: the Macrogol 4000 weight ratio is 1: (0.2～0.5): (1.5～2), the PEG400 and the Macrogol 4000 of described proportioning are mixed, slowly be heated to molten condition, slowly add extract, mix homogeneously, make medicinal liquid, 80 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 80 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, get final product.
During above-mentioned steps (2) preparation medicinal liquid, extract: PEG400: the Macrogol 4000 weight ratio is 1: 0.3: 1.7.
Ginseng stilbene schisandra fruit dripping pill according to claim 1 is characterized in that: when described step (3) was dripped the system drop pill, dripping speed was excellent with 40～45/minute, and coolant is excellent with liquid paraffin.
Compared with prior art, the invention has the beneficial effects as follows: medicinal dropping ball of the present invention has the effect of replenishing QI to invigorate the spleen, mind tranquilizing and the heart calming, and after Shi Yi method was extracted whole raw medicinal materials excessively, wherein active component concentration was higher, and onset is faster, dose is littler; And the quality control that helps preparation improves drug quality; Also the simplified operation flow process shortens the production cycle.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Following each present embodiment ginseng stilbene schisandra fruit dripping pill all makes with following amount amount part proportion raw material medicine:
6 parts of Fructus Schisandrae Sphenantheraes, 2 parts of Radix Codonopsis, 4 parts of the Radixs Astragali, 1 part of Semen Ziziphi Spinosae (parched).
Embodiment 1
Present embodiment ginseng stilbene schisandra fruit dripping pill makes according to the method that comprises the steps:
(1), extract raw medicinal material: get each crude drug of described proportioning, mix, add 60% alcohol reflux 3 times, merge extractive liquid,, reclaim ethanol, reconcentration is dried to dry extract, makes extract;
(2), preparation medicinal liquid: according to extract: PEG400: the Macrogol 4000 weight ratio is 1: 0.2: 1.8, the PEG400 and the Macrogol 4000 of described proportioning are mixed, slowly be heated to molten condition, slowly add extract, mix homogeneously, make medicinal liquid, 80 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 80 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, dripping speed is 40/minute, and coolant is a liquid paraffin.
Embodiment 2
Present embodiment ginseng stilbene schisandra fruit dripping pill makes according to the method that comprises the steps:
(1), extract raw medicinal material: get each crude drug of described proportioning, mix, add 75% alcohol reflux 2 times, merge extractive liquid,, reclaim ethanol, reconcentration is dried to dry extract, makes extract;
(2), preparation medicinal liquid: according to extract: PEG400: the Macrogol 4000 weight ratio is 1: 0.5: 1.5, the PEG400 and the Macrogol 4000 of described proportioning are mixed, slowly be heated to molten condition, slowly add extract, mix homogeneously, make medicinal liquid, 80 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 80 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, dripping speed is 45/minute, and coolant is a liquid paraffin.
Embodiment 3
Present embodiment ginseng stilbene schisandra fruit dripping pill makes according to the method that comprises the steps:
(1), extract raw medicinal material: get each crude drug of described proportioning, mix, add 70% alcohol reflux 3 times, merge extractive liquid,, reclaim ethanol, reconcentration is dried to dry extract, makes extract;
(2), preparation medicinal liquid: according to extract: PEG400: the Macrogol 4000 weight ratio is 1: 0.3: 1.7, the PEG400 and the Macrogol 4000 of described proportioning are mixed, slowly be heated to molten condition, slowly add extract, mix homogeneously, make medicinal liquid, 80 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 80 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, dripping speed is 42/minute, and coolant is a liquid paraffin.
Claims (3)
1. a seed ginseng stilbene schisandra fruit dripping pill, with following amount amount part proportion raw material medicine:
6 parts of Fructus Schisandrae Sphenantheraes, 2 parts of Radix Codonopsis, 4 parts of the Radixs Astragali, 1 part of Semen Ziziphi Spinosae (parched),
Make according to the method that comprises the steps:
(1), extract raw medicinal material: get each crude drug of described proportioning, mix, add 60-75% alcohol reflux 2-3 time, merge extractive liquid,, recovery ethanol, reconcentration is dried to dry extract, makes extract;
(2), preparation medicinal liquid: according to extract: PEG400: the Macrogol 4000 weight ratio is 1: (0.2～0.5): (1.5～2), the Macrogol 4000 and the polyethylene glycol 6000 of described proportioning are mixed, slowly be heated to molten condition, slowly add extract, mix homogeneously, make medicinal liquid, 80 ± 2 ℃ of insulations, standby;
(3), drip the system drop pill: under 80 ± 2 ℃ of conditions, the medicine liquid droplet that (2) step makes is made drop pill, get final product.
2. ginseng stilbene schisandra fruit dripping pill according to claim 1 is characterized in that: during described step (2) preparation medicinal liquid, extract: PEG400: the Macrogol 4000 weight ratio is 1: 0.3: 1.7.
3. ginseng stilbene schisandra fruit dripping pill according to claim 1 is characterized in that: when described step (3) was dripped the system drop pill, dripping speed was 40～45/minute, and coolant is a liquid paraffin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102527070A CN102085254A (en) | 2009-12-02 | 2009-12-02 | Codonopsis pilosula, radix astragali and kadsura longepedunculata dripping pill |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102527070A CN102085254A (en) | 2009-12-02 | 2009-12-02 | Codonopsis pilosula, radix astragali and kadsura longepedunculata dripping pill |
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| CN102085254A true CN102085254A (en) | 2011-06-08 |
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| CN2009102527070A Pending CN102085254A (en) | 2009-12-02 | 2009-12-02 | Codonopsis pilosula, radix astragali and kadsura longepedunculata dripping pill |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697891A (en) * | 2012-06-15 | 2012-10-03 | 李良 | Astragalus Chinese medicinal decoction for treating palpitation and preparation method thereof |
| CN108185023A (en) * | 2017-12-21 | 2018-06-22 | 陇南市朝华核桃产业开发有限公司 | A kind of Walnut oil dropping pills for promoting infant development and preparation method thereof |
| CN113827648A (en) * | 2021-10-28 | 2021-12-24 | 深圳市艾普生物科技有限公司 | Traditional Chinese medicine composition with nerve calming and sleep aiding effects and preparation method and application thereof |
-
2009
- 2009-12-02 CN CN2009102527070A patent/CN102085254A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697891A (en) * | 2012-06-15 | 2012-10-03 | 李良 | Astragalus Chinese medicinal decoction for treating palpitation and preparation method thereof |
| CN108185023A (en) * | 2017-12-21 | 2018-06-22 | 陇南市朝华核桃产业开发有限公司 | A kind of Walnut oil dropping pills for promoting infant development and preparation method thereof |
| CN113827648A (en) * | 2021-10-28 | 2021-12-24 | 深圳市艾普生物科技有限公司 | Traditional Chinese medicine composition with nerve calming and sleep aiding effects and preparation method and application thereof |
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Application publication date: 20110608 |