CN102068642A - Medicinal composition for treating skin tinea and preparation method and application thereof - Google Patents
Medicinal composition for treating skin tinea and preparation method and application thereof Download PDFInfo
- Publication number
- CN102068642A CN102068642A CN2009102163360A CN200910216336A CN102068642A CN 102068642 A CN102068642 A CN 102068642A CN 2009102163360 A CN2009102163360 A CN 2009102163360A CN 200910216336 A CN200910216336 A CN 200910216336A CN 102068642 A CN102068642 A CN 102068642A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- preparation
- medicinal composition
- tinea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention belongs to the field of medicaments, and particularly relates to a medicinal composition for treating skin tinea and a preparation method and application thereof. The invention aims to provide a brand-new medicinal composition for treating the skin tinea, which consists of 5 to 10 parts of fructus cnidii, 5 to 10 parts of sessile stemona root, 3 to 7 parts of Saposhnikovia divaricata, 4 to 8 parts of Chinese angelica, 4 to 8 parts of cicada slough, 5 to 10 parts of pepper, and 0.5 to 2 parts of borneol, and is an externally applied preparation prepared by taking the crude drugs as active ingredients and adding pharmaceutically accepted excipients into the crude drugs. Particularly, the medicinal composition can be prepared into common formulations such as lotions, ointments, emulsions and the like. The clinical medication shows that the medicinal composition has definite therapeutic effect, has the efficacies in dispelling wind, removing damp and relieving itching, and is used for treating tinea manuum, tinea pedis and tinea corporis.
Description
Technical field
The invention belongs to field of medicaments, particularly a kind of pharmaceutical composition for the treatment of the skin ringworm and its production and use.
Background technology
Tinea (hands, foot, tinea corporis) is the dermatosis that is caused by mycete (fungus).With the skin pruritus is cardinal symptom.Treat the external preparation such as ointment, emulsifiable paste and disinfectant preparation that the medicine of above-mentioned disease is made more, based on antipruritic.
Chinese patent publication number CN1939522A, application number 200510107769.4, treating dermopathic external preparation and preparation method thereof discloses a kind of to be the dermopathic external preparation of treatment of active drug composition by natural drug Radix Et Rhizoma Rhei, Rhizoma Curcumae Longae, sulfur, Radix Scutellariae, Radix Glycyrrhizae, Borneolum Syntheticum, Mentholum, to be used for the skin pruritus that damp-heat accumulation or heat in blood wind-dryness cause; Neurodermatitis, warm rash and cause hands, foot, tinea corporis because of various funguses, antibacterial, infected by microbes.
Summary of the invention
The purpose of this invention is to provide a kind of brand-new medicinal composition and be used for the treatment of the skin ringworm.
Pharmaceutical composition of the present invention is made up of Fructus Cnidii 5-10 part, Radix Stemonae 5-10 part, Radix Saposhnikoviae 3-7 part, Radix Angelicae Sinensis 4-8 part, Periostracum Cicadae 4-8 part, Pericarpium Zanthoxyli 5-10 part, Borneolum Syntheticum 0.5-2 part.
Determine that by screening test 7.5 parts of Fructus Cnidiis, 7.5 parts of the Radixs Stemonae, 5 parts of Radix Saposhnikoviaes, 6 parts of Radix Angelicae Sinensis, 6 parts of Periostracum Cicadaes, 7.5 parts in Pericarpium Zanthoxyli, 1 part of therapeutic effect of Borneolum Syntheticum are the clearest and the most definite, the most stable.
Pharmaceutical composition of the present invention has and dispels the wind, and dehumidifying is antipruritic, is used for the treatment of hands, foot, tinea corporis.
When pharmaceutical composition of the present invention is used, be to be active component, add the external preparation that acceptable accessories is made with Fructus Cnidii, the Radix Stemonae, Radix Saposhnikoviae, Radix Angelicae Sinensis, Periostracum Cicadae, Pericarpium Zanthoxyli, Borneolum Syntheticum.Specifically can be made into common dosage forms such as lotion, ointment, Emulsion, easy to use, easy to carry.
Second purpose of the present invention provides the preparation of drug combination method of this treatment treatment skin ringworm, it is characterized in that it comprises the steps:
A, take by weighing Fructus Cnidii 5-10 part, Radix Stemonae 5-10 part, Radix Saposhnikoviae 3-7 part, Radix Angelicae Sinensis 4-8 part, Periostracum Cicadae 4-8 part, Pericarpium Zanthoxyli 5-10 part, Borneolum Syntheticum 0.5-2 part, be ground into coarse powder;
B, employing percolation extract, and solvent is the solvent composition of following volume ratio: 1 part in ethanol 1-5 part, glacial acetic acid; 3 parts of preferred alcohols, 1 part in glacial acetic acid;
C, dipping 36-72 hour, the beginning percolation is collected the percolate that 6-12 doubly measures, and leaves standstill, and gets supernatant, makes external preparation according to the pharmaceutics conventional method.
Preparation method of the present invention is simple, can make stable, controlled preparation, and the preparation effect is clear and definite.
The specific embodiment
Below adopt the beneficial effect of clinical data proof medicine of the present invention.
Press the proportioning of table 1, each raw material powder is broken into coarse powder, adopt the solvent percolation of 3 parts of ethanol, 1 part in glacial acetic acid to extract: flooded 48 hours, the beginning percolation is collected the percolate of 10 times of amounts, leaves standstill, and gets supernatant, gets final product.
The proportioning of each crude drug of table 1
The inventor adopts the medicine of the present invention of embodiment 1-5 preparation to be used for the treatment of hands, foot, tinea corporis, through 500 routine clinical observations (No. 1 prescription 100 examples, No. 2 prescription 100 examples, No. 3 prescription 100 examples, No. 4 prescription 100 examples, No. 5 prescription 100 examples), total effective rate all reaches more than 85%, and wherein No. 1 prescription effective percentage is that 96.5%, No. 2 prescription effective percentage is 90.3%, No. 3 prescription effective percentage are that 89.7%, No. 4 prescription effective percentage is that 91.7%, No. 5 prescription effective dose is 92.6.
Claims (8)
1. treat the pharmaceutical composition of skin ringworm, it is characterized in that it is made up of following materials of weight proportions medicine:
Fructus Cnidii 5-10 part, Radix Stemonae 5-10 part, Radix Saposhnikoviae 3-7 part, Radix Angelicae Sinensis 4-8 part, Periostracum Cicadae 4-8 part, Pericarpium Zanthoxyli 5-10 part, Borneolum Syntheticum 0.5-2 part.
2. the pharmaceutical composition of treatment skin ringworm according to claim 1 is characterized in that, it is made up of following materials of weight proportions medicine:
7.5 parts of Fructus Cnidiis, 7.5 parts of the Radixs Stemonae, 5 parts of Radix Saposhnikoviaes, 6 parts of Radix Angelicae Sinensis, 6 parts of Periostracum Cicadaes, 7.5 parts in Pericarpium Zanthoxyli, 1 part of Borneolum Syntheticum.
3. the pharmaceutical composition of treatment skin ringworm according to claim 1 and 2 is characterized in that, it is to be active component with Fructus Cnidii, the Radix Stemonae, Radix Saposhnikoviae, Radix Angelicae Sinensis, Periostracum Cicadae, Pericarpium Zanthoxyli, Borneolum Syntheticum, adds the external preparation that acceptable accessories is made.
4. the pharmaceutical composition of treatment skin ringworm according to claim 3 is characterized in that, described external preparation is lotion, ointment, Emulsion.
5. the preparation of drug combination method of the described treatment skin of claim 1 ringworm is characterized in that step is as follows:
A, take by weighing Fructus Cnidii 5-10 part, Radix Stemonae 5-10 part, Radix Saposhnikoviae 3-7 part, Radix Angelicae Sinensis 4-8 part, Periostracum Cicadae 4-8 part, Pericarpium Zanthoxyli 5-10 part, Borneolum Syntheticum 0.5-2 part, be ground into coarse powder;
B, employing percolation extract, and solvent is the solvent composition of following volume ratio: 1 part in ethanol 1-5 part, glacial acetic acid;
C, dipping 36-72 hour, the beginning percolation is collected the percolate that 6-12 doubly measures, and leaves standstill, and gets supernatant, makes external preparation according to the pharmaceutics conventional method.
6. the preparation of drug combination method of treatment skin ringworm according to claim 5 is characterized in that, steps A takes by weighing 7.5 parts of Fructus Cnidiis, 7.5 parts of the Radixs Stemonae, 5 parts of Radix Saposhnikoviaes, 6 parts of Radix Angelicae Sinensis, 6 parts of Periostracum Cicadaes, 7.5 parts in Pericarpium Zanthoxyli, 1 part of Borneolum Syntheticum.
7. the preparation of drug combination method of treatment skin ringworm according to claim 5 is characterized in that, solvent is the solvent composition of following volume ratio among the step B: 3 parts of ethanol, 1 part in glacial acetic acid.
8. the purposes of the described pharmaceutical composition of claim 1 in the medicine of preparation treatment hands, foot, tinea corporis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102163360A CN102068642A (en) | 2009-11-25 | 2009-11-25 | Medicinal composition for treating skin tinea and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102163360A CN102068642A (en) | 2009-11-25 | 2009-11-25 | Medicinal composition for treating skin tinea and preparation method and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102068642A true CN102068642A (en) | 2011-05-25 |
Family
ID=44027522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102163360A Pending CN102068642A (en) | 2009-11-25 | 2009-11-25 | Medicinal composition for treating skin tinea and preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102068642A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266860A (en) * | 2015-06-06 | 2017-01-04 | 陈冠卿 | A kind of medicated powder treating tinea corporis and cruris |
| CN110946949A (en) * | 2019-12-18 | 2020-04-03 | 白遥 | Traditional Chinese medicine formula for clearing collaterals and dispelling wind and acupuncture method using traditional Chinese medicine formula |
-
2009
- 2009-11-25 CN CN2009102163360A patent/CN102068642A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266860A (en) * | 2015-06-06 | 2017-01-04 | 陈冠卿 | A kind of medicated powder treating tinea corporis and cruris |
| CN110946949A (en) * | 2019-12-18 | 2020-04-03 | 白遥 | Traditional Chinese medicine formula for clearing collaterals and dispelling wind and acupuncture method using traditional Chinese medicine formula |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103893727A (en) | Pain-relieving, blood-invigorating and tendon-relaxing plaster and preparation method thereof | |
| CN101062289A (en) | External application medicine combination for treating gout | |
| CN102058673B (en) | Chinese medicine composition for expelling wind and removing dampness and preparation method thereof | |
| Villanueva et al. | Solving the puzzle: What is behind our forefathers’ anti-inflammatory remedies? | |
| Zheng et al. | Ephedrae herba: A comprehensive review of its traditional uses, phytochemistry, pharmacology, and toxicology | |
| CN103386022B (en) | Chinese medicine composition for treating tuberculous pleurisy | |
| CN102688327B (en) | Medicine composition of damp itch lotion and preparation method of medicine composition | |
| CN101664482B (en) | Externally-applied medicine for treating beriberi and skin pruritus and preparation method thereof | |
| Thounaojam et al. | Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb leaf extract | |
| CN102068642A (en) | Medicinal composition for treating skin tinea and preparation method and application thereof | |
| CN102145091B (en) | Traditional Chinese medicinal composition for eliminating wind and relieving heat and preparation method thereof | |
| CN103585545B (en) | Traditional Chinese medicine composition for treating otitis media | |
| CN101337026A (en) | External medicine composition for treating gout | |
| WO2019142042A1 (en) | Synergistic medicinal preparation for treating skin disorders like tinea versicolor | |
| CN1954841B (en) | Medicine for treating chronic pharyngitis | |
| TWI409076B (en) | Medical herb composition for increasing inflammation, swell and pain, method for manufacturing medical herb abstract, application for the same | |
| CN108434227A (en) | A kind of drug for treating tinea pedis | |
| Klein et al. | Occurrence of chai hu (Bupleuri radix) in prescriptions of Chinese herbal medicine in Switzerland | |
| CN103142928A (en) | Iliacus muscle oral liquid and preparation method thereof | |
| CN100496600C (en) | Medicine for treating osteoporosis and its preparation method | |
| CN103127255A (en) | Antioxidant externally-applied Chinese medicine dressing formula for treating asthma and preparation method thereof | |
| CN109806321B (en) | A Chinese medicinal composition, its preparation method and application in preparing medicine for treating trauma | |
| CN103520475B (en) | A kind of pharmaceutical composition being used for the treatment of skin pruritus | |
| CN102145092B (en) | Chinese medical composition capable of dispelling wind and relieving fever and preparation method | |
| CN101711842B (en) | Efficient pure Chinese medicinal anti-inflammation and itching-relieving liquid, and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110525 |