CN102068635B - Traditional Chinese medicine for treating refractory pruritus - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating refractory pruritus, which is characterized by being prepared from the following raw materials by weight: 6 to 12 grams of phellodendron, 9 to 30 grams of rehmanniae praeparatum, 6 to 12 grams of fructus tribuli, 6 to 12 grams of divaricate saposhnikovia root, 6 to 12 grams of fineleaf schizonepeta herb, 3 to 6 grams of szechuanlovage rhizome, 6 to 12 grams of red paeony root, 6 to 12 grams of Chinese angelica, 12 to 30 grams of coix seed, 6 to 9 grams of cortex moutan, 6 to 9 grams of alisma orientale, 9 to 12 grams of dictamnus bark, 12 to 30 grams of belvedere fruit, 4.5 to 9 grams of siberian cocklour fruit and 6 to 12 grams of beautiful sweetgum fruit. Compared with the prior art, the invention provides an internaland external-relieving traditional Chinese medicine for treating the refractory pruritus, wherein the fructus tribuli is used for invigorating blood circulation, dispelling wind and arresting itching, the phellodendron, the cortex moutan, the alisma orientale and the coix seed are used for clearing heat and drying damp, the fineleaf schizonepeta herb, the divaricate saposhnikovia root, the dictamnus bark, the belvedere fruit, the lightyellow sophora root and the siberian cocklour fruit are used for dispelling wind, arresting itching and killing worms, the beautiful sweetgum fruit is used for dispelling wind, removing obstruction in channels, inducing diuresis and dehumidifying, and the Chinese angelica, the szechuan lovage rhizome, the red paeony root and the rehmanniae praeparatum are used for enriching, nourishing and cooling blood. The traditional Chinese medicine attacks pathogenic factors without hurting vital qi to achieve the effects of clearing heat and drying damp and dispelling wind and arresting itching, and has a good curative effect on diseases which does not have obvious pathogenesis to study, the refractory pruritus and yin-deficiency.

Description

A kind of Chinese medicine of treating the intractable skin pruritus

Technical field

The present invention relates to field of Chinese herbal, specifically refer to a kind of Chinese medicine of treating the intractable skin pruritus.

Background technology

The intractable skin pruritus is commonly considered as being caused by the skin immunization gene impairing, is a kind of chronic dermatosis that does not have former skin lesion.A lot of skin prurituss do not have the obvious cause of disease and can study carefully among the crowd, can be taken place by stimulation such as some disease, medicine, cold, woolen knitwear allergy, belong to function of nervous system's sexual disorders, are a kind of clinical common but dermatosis of being difficult to cure fully.Especially old intractable skin pruritus; There is pruritus more than half not have cause specific; This possibly be because old people's skin aging, smegma minimizing, xerosis cutis, degree of hydration are lower; Be prone to produce the local material that causes the character of itching,, or some is caused the material sensitive property of itching increase like cytokine etc.The intractable skin pruritus of persistence can be brought spirit and insufferable misery animally to the patient.Grab because acutely scratch, cause black and bluely, often show that skin significantly thickens, leather, hemorrhage, incrustation, secondary infection etc.

At present the intractable skin pruritus of treatment in, Western medicine all has application.Like the oral antihistamines in the Western medicine, calcium preparation, vitamin A, vitamin C and compound vitamin B.The traditional Chinese medical science thinks that then primary disease belongs to blood-deficiency and wind-dry, the treatment skin moistening that should nourish blood, and dispelling wind is antipruritic.Common Chinese medicine preparation has: Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, windproof each 10 gram, the Radix Rehmanniae, Radix Rehmanniae Preparata, Caulis Spatholobi, Caulis Polygoni Multiflori, Fructus Tribuli, each 15 gram of the Fructus Kochiae.Be decocted in water for oral dose 1 dose of every day 2 times.These two kinds of methods all can adopt the external used medicine auxiliary treatment, for example at local corticosteroid hormone ointment or frost and antipruritic liquid medicine and the skin moistening liquid medicine etc. of using of pruritus.The poor effect that the medicine of above-mentioned these existing treatment intractable skin pruritus, the side effect that has be too big, have, have the taboo of use arranged.

Summary of the invention

Technical problem to be solved by this invention is that the present situation to prior art provides determined curative effect, the Chinese medicine of the treatment intractable skin pruritus that has no side effect, and this Chinese medicine can be taken for a long time, and has treatment and preventive effect simultaneously.

The present invention solves the problems of the technologies described above the technical scheme that is adopted: the Chinese medicine of this treatment intractable skin pruritus is characterized in that being processed by following materials of weight proportions:

Cortex Phellodendri 6-12g, Radix Rehmanniae 9-30g, Fructus Atriplicis Sibiricae 6-12g, windproof 6-12g, Herba Schizonepetae 6-12g; Rhizoma Chuanxiong 3-6g, Radix Paeoniae Rubra 6-12g, Radix Angelicae Sinensis 6-12g, Semen Coicis 12-30g, Cortex Moutan 6-9g; Rhizoma Alismatis 6-9g, Cortex Dictamni 9-12g, Fructus Kochiae 12-30g, Fructus Xanthii 4.5-9g, Fructus Liquidambaris 6-12g.

The present invention selects the said medicine combination to use, and makes each efficacy of drugs produce synergism, thereby can effectively treat the intractable skin pruritus.

Wherein:

Cortex Phellodendri: claim Clausena lansium (Lour.) Skeels, Cortex Phellodendri, Cortex Phellodendri, Cortex Phellodendri, yellow spinach sieve again; Be heat clearing and dampness removing medicine, return kidney, urinary bladder channel, nature and flavor are bitter, cold; Has heat clearing and damp drying; Pathogenic fire purging removes steams, and the performance of skin ulcer is treated in detoxifcation, is used for hyperactivity of fire caused by deficiency of YIN, damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.

The Radix Rehmanniae: nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, and clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid, and is used for that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, sends out the speckle dermexanthesis.

Tribulus terrestris: nature and flavor are bitter, hot, flat, go into Liver Channel, soothing liver-qi stagnation, wind-expelling pain-stopping, benefiting shrewd head, be used to treat nephrasthenia lumbago, seminal emission band down, headache, the many tears of hot eyes, cough that contrary consumptive lung disease, crux are gathered, breast closes obstructed, pruitus, rubella, leucoderma.

Windproof: nature and flavor are hot, sweet, warm, return bladder, liver, spleen channel, cure mainly inducing diaphoresis to dispel wind, win wet, relieving convulsion, are used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.

Herba Schizonepetae: hot, the tepor of nature and flavor, return lung, Liver Channel, have the diffusing wind that induces sweat, rash, the skin ulcer that disappears, hemostatic function, cure mainly that flu, measles are passed through and sent out not freely, have blood in stool, metrorrhagia, epistaxis.

Rhizoma Chuanxiong: nature and flavor are hot, warm, go into liver, gallbladder meridian, have that activating QI to alleviate the depression, method wind-dryness are wet, the function of promoting blood circulation and stopping pain, cure mainly control air-cooled headache revolve dizzy, the hypochondriac pain abdomen painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.

Radix Paeoniae Rubra: nature and flavor are bitter, be slightly cold, and return Liver Channel, have the function of clearing away heat and cooling blood, eliminating stasis to stop pain, cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea 、 mass in the abdomen stomachache, injury from falling down, carbuncle skin infection.

Radix Angelicae Sinensis: nature and flavor are sweet, hot, warm; Return liver, the heart, spleen channel; Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, and the function of loosening bowel to relieve constipation cures mainly blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Semen Coicis: claim Semen Coicis again, nature and flavor are sweet, light, cool, return spleen, stomach, lung meridian, have spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, the dense function of heat clearing away row, cure mainly edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis, verruca plana.

Cortex Moutan: nature and flavor are hot, bitter, be slightly cold, and go into the heart, liver, kidney channel, have the effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, cure mainly maculae caused by violent heat pathogen, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, fall and pounce on the pain of injury.

Rhizoma Alismatis: have another name called marshy land, Rhizoma Alismatis, car Herba Sonchi Oleracei, TIAN'EDAN, day bald, YIZHIHUA, nature and flavor are sweet, cold, return kidney, urinary bladder channel.Function with diuresis, clearing away damp-heat cures mainly dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipidemia.

Cortex Dictamni: the nature and flavor hardship is salty, cold, goes into spleen, stomach warp, have dispel the wind, dampness, heat clearing away, antidotal effect, cure mainly wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.

The Fructus Kochiae: another name broom, DIKUI, wheat, benefit bright, nature and flavor are bitter, cold, return urinary bladder channel, have heat clearing away, diuresis, itching relieving effect, cure mainly dysuria, drench the puckery pain of drop, pruritus, eczema all over the body.

Xanthium: Alias cocklebur, old Cubeba, Cubeba, Xi ears, dark green thorn, hair Cubeba, crazy head shoved, sheep with normalization, of spicy, bitter, warm, the lung, with scattered wind and dampness, the efficacy of the nasal passage, attending cold, headache, runny nose Biyuan, rubella itching, dampness Spasm.

Fructus Liquidambaris: the another name Fructus Liquidambaris, nature and flavor are bitter, flat, return liver, kidney channel, have the effect that dispelling, collateral-activating, diuretic stimulate the menstrual flow, and cure mainly arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.

Drug component of the present invention and consumption thereof are through inventor's long-term clinical and carried out groping in a large number, adjusted the back summary draws.Usually, each component can obtain better therapeutic when following dosage:

Cortex Phellodendri 9g, Radix Rehmanniae 19g, Fructus Atriplicis Sibiricae 9g, windproof 9g, Herba Schizonepetae 9g, Rhizoma Chuanxiong 5g, Radix Paeoniae Rubra 9g, Radix Angelicae Sinensis 9g, Semen Coicis 20g, Cortex Moutan 7g, Rhizoma Alismatis 8g, Cortex Dictamni 11g, Fructus Kochiae 23g, Fructus Xanthii 7g, Fructus Liquidambaris 9g.

The method for using of Chinese medicine of the present invention is conventional decocting, oral behind the water preparation.

According to the clinical operating position of this medicine in recent years, added up 145 routine intractable skin pruritus patients and used the situation behind this medicine following:

Total case 145 examples, wherein male 97 examples, women 48 examples, age 35-55 year 111 examples, 34 examples more than 55 years old.Therapeutic Method is for being decocted in water for oral dose.Wherein cure 140 examples, 3 examples that take a turn for the better, effective 2 examples.Medication healing person's 1 course of treatment 89 examples, 2 the course of treatment healing person's 51 examples, the wherein per medication course of treatment 3 days, 1 dose of medication every day is divided into two parts with the gained water preparation behind the decocting, sooner or later sub-service.Do not see untoward reaction in the therapeutic process.The so-called healing is the pruritus complete obiteration, and do not have recurrence, transfers pruritus to well to alleviate, and effectively takes a turn for the better for subjective symptoms.

Compared with prior art; A kind of Chinese medicine of treatment intractable skin pruritus of relieving exterior-interior syndrome is provided among the present invention, and wherein disease Herba chenopodii promoting blood circulation by removing wind is antipruritic, Cortex Phellodendri, Cortex Moutan, Rhizoma Alismatis Semen Coicis heat clearing and damp drying; Herba Schizonepetae, windproof, Cortex Dictamni, the Fructus Kochiae, Radix Sophorae Flavescentis, Fructus Xanthii dispelling wind for relieving itching parasite killing; Fructus Liquidambaris dispelling wind and removing obstruction in the collateral diuretic dehumidifying, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Rehmanniae blood-supplementing blood-nourishing removing heat from blood make and attack heresy and just do not hinder; Thereby reach the effect of heat clearing and damp drying, dispelling wind for relieving itching, can not study carefully intractable skin pruritus and deficiency of YIN wind-dryness property skin pruritus etc. is had curative effect preferably there being the obvious cause of disease.

The specific embodiment

Embodiment describes in further detail the present invention below in conjunction with accompanying drawing.

Preparation example 1

Cortex Phellodendri 9g, Radix Rehmanniae 19g, Fructus Atriplicis Sibiricae 9g, windproof 9g, Herba Schizonepetae 9g, Rhizoma Chuanxiong 5g, Radix Paeoniae Rubra 9g, Radix Angelicae Sinensis 9g, Semen Coicis 20g, Cortex Moutan 7g, Rhizoma Alismatis 8g, Cortex Dictamni 11g, Fructus Kochiae 23g, Fructus Xanthii 7g, Fructus Liquidambaris 9g is decocted in water for oral dose.

Preparation example 2

Cortex Phellodendri 6g, Radix Rehmanniae 10g, Fructus Atriplicis Sibiricae 12g, windproof 8g, Herba Schizonepetae 12g, Rhizoma Chuanxiong 6g, Radix Paeoniae Rubra 6g, Radix Angelicae Sinensis 12g, Semen Coicis 12g, Cortex Moutan 6g, Rhizoma Alismatis 9g, Cortex Dictamni 9g, Fructus Kochiae 30g, Fructus Xanthii 9g, Fructus Liquidambaris 6g is decocted in water for oral dose.

Preparation example 3

Cortex Phellodendri 12g, Radix Rehmanniae 20g, Fructus Atriplicis Sibiricae 6g, windproof 6g, Herba Schizonepetae 6g, Rhizoma Chuanxiong 3g, Radix Paeoniae Rubra 12g, Radix Angelicae Sinensis 6g, Semen Coicis 30g, Cortex Moutan 9g, Rhizoma Alismatis 6g, Cortex Dictamni 12g, Fructus Kochiae 12g, Fructus Xanthii 4.5, Fructus Liquidambaris 12g is decocted in water for oral dose.

Preparation example 4

Cortex Phellodendri 10g, Radix Rehmanniae 30g, Fructus Atriplicis Sibiricae 11g, windproof 12g, Herba Schizonepetae 10g, Rhizoma Chuanxiong 4g, Radix Paeoniae Rubra 10g, Radix Angelicae Sinensis 10g, Semen Coicis 25g, Cortex Moutan 8g, Rhizoma Alismatis 7g, Cortex Dictamni 10g, Fructus Kochiae 20g, Fructus Xanthii 5g, Fructus Liquidambaris 10g is decocted in water for oral dose.

Case report

1, Wang, the man, 49 years old, beginning skin was very itched and is felt bad, and hands, foot, pudendum have red dominance rash point, speckle, and the red tongue tongue is white, uses plurality of Chinese, Western medicine, and it is invalid to seek medical advice for many years.

Cure after taking 1 three doses of preparation examples continuously, do not have recurrence so far.

2, Ma, woman, 58 years old.Skin pruritus 1 year, before sleeping and morning time-out for very, have slightly daytime and air-cooledly also repeatedly show effect.Whole skin the. fugitive pruritus, the local flushing of grabbing plays little red pimple subsequently.Timid usually cold, light red tongue, white and thin fur, moderate pulse.

The pruritus area dwindles after serveing on 1 three doses of embodiment, and the time shortens.Obey three doses of healings again.Observe half a year, not recurrence.

3, Liu, man, 50 years old.Skin pruritus 2 years.No obvious inducement before 3 days and whole body play the red point of needle point size, itch very.Dizzy vexed, poor, the xerostomia of sleeping of companion, red urine are lacked.Body of the tongue is dark red, and tongue is few, thready and rolling pulse.

Cure after serveing on 2 three doses of preparation examples, observe not have in three months and recur.

4, Zhang, man, 32 years old; Biped back and toes seam show effect the repeatedly pimple or the vesicle of foxtail millet grain size, pruritus unbearably, local surfaces is with squama companion scratch, pigmentation; It is heavy when time thes be light; The existing several months, take antibiotic, prednisone, chlorphenamine, external fluocinonide, miconazole etc. are with to cooperate heat-clearing and toxic substances removing, the treatment of removing dampness to relieve itching Chinese medicine decoction all invalid.

Cure after serveing on 3 three doses of embodiment, follow up a case by regular visits to and do not have recurrence in 1 year.

5, week certain, the man, 73 years old, suffer from the intractable skin pruritus, reach 20 surplus year, control repeatly when the ground warp Chinese and western medicine invalid.

Pruritus alleviates after serveing on 4 seven doses of preparation examples, and midfeather serve on seven doses of healings again after 20 days.

7, Wang, the man, 67 years old, suffering from skin pruritus had more than ten years.Every day arm, back, pruritus all can be felt in positions such as waist, grabs and later will play hard one by one parcel, stings as mosquito, bag scratches that the back is hemorrhage oneself forms a scab then, itches not only then but also a bag of itching very much.Ate and used a lot of medicines, but still recurred after controlling a period of time, can not effect a radical cure.

After taking 3 five doses of embodiment continuously, transference cure, after take three doses again.So far not recurrence.

Claims (2)

1. Chinese medicine of treating the intractable skin pruritus is characterized in that being processed by following materials of weight proportions:

Cortex Phellodendri 6-12g, Radix Rehmanniae 9-30g, Fructus Atriplicis Sibiricae 6-12g, windproof 6-12g, Herba Schizonepetae 6-12g; Rhizoma Chuanxiong 3-6g, Radix Paeoniae Rubra 6-12g, Radix Angelicae Sinensis 6-12g, Semen Coicis 12-30g, Cortex Moutan 6-9g; Rhizoma Alismatis 6-9g, Cortex Dictamni 9-12g, Fructus Kochiae 12-30g, Fructus Xanthii 4.5-9g, Fructus Liquidambaris 6-12g.

2. the Chinese medicine of treatment intractable skin pruritus according to claim 1 is characterized in that the weight proportion of each raw material is:

Cortex Phellodendri 9g, Radix Rehmanniae 19g, Fructus Atriplicis Sibiricae 9g, windproof 9g, Herba Schizonepetae 9g, Rhizoma Chuanxiong 5g, Radix Paeoniae Rubra 9g, Radix Angelicae Sinensis 9g, Semen Coicis 20g, Cortex Moutan 7g, Rhizoma Alismatis 8g, Cortex Dictamni 11g, Fructus Kochiae 23g, Fructus Xanthii 7g, Fructus Liquidambaris 9g.