CN102056484B - 用于热潮红的类固醇治疗 - Google Patents

用于热潮红的类固醇治疗 Download PDF

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Publication number
CN102056484B
CN102056484B CN200980121663.6A CN200980121663A CN102056484B CN 102056484 B CN102056484 B CN 102056484B CN 200980121663 A CN200980121663 A CN 200980121663A CN 102056484 B CN102056484 B CN 102056484B
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China
Prior art keywords
epoxy
female
hot flashes
hydroxy
beta
Prior art date
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Application number
CN200980121663.6A
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English (en)
Chinese (zh)
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CN102056484A (zh
Inventor
路易斯·蒙蒂
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Pherin Pharmaceuticals Inc
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Pherin Pharmaceuticals Inc
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Publication of CN102056484A publication Critical patent/CN102056484A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
CN200980121663.6A 2008-04-09 2009-04-09 用于热潮红的类固醇治疗 Active CN102056484B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12362208P 2008-04-09 2008-04-09
US61/123,622 2008-04-09
PCT/US2009/040102 WO2009126825A1 (en) 2008-04-09 2009-04-09 Steroid treatment for hot flashes

Publications (2)

Publication Number Publication Date
CN102056484A CN102056484A (zh) 2011-05-11
CN102056484B true CN102056484B (zh) 2014-10-29

Family

ID=41162250

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980121663.6A Active CN102056484B (zh) 2008-04-09 2009-04-09 用于热潮红的类固醇治疗

Country Status (10)

Country Link
US (2) US20090258040A1 (cg-RX-API-DMAC7.html)
EP (1) EP2278880B1 (cg-RX-API-DMAC7.html)
JP (1) JP5524177B2 (cg-RX-API-DMAC7.html)
KR (1) KR101602802B1 (cg-RX-API-DMAC7.html)
CN (1) CN102056484B (cg-RX-API-DMAC7.html)
AU (1) AU2009234159B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0910637A2 (cg-RX-API-DMAC7.html)
DK (1) DK2278880T3 (cg-RX-API-DMAC7.html)
MX (1) MX2010011063A (cg-RX-API-DMAC7.html)
WO (1) WO2009126825A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3068590A1 (en) 2017-07-06 2019-01-10 Dignity Health Novel treatment for hot flushes
KR20210151836A (ko) 2019-04-15 2021-12-14 페린 파마슈티칼즈, 인코포레이티드 편두통의 치료
WO2024254005A1 (en) * 2023-06-04 2024-12-12 Vistagen Therapeutics, Inc. 1,3,5(10),16-estratetraen-3-yl acetate for use in improving psychomotor or cognitive performance
US20250312356A1 (en) * 2024-04-08 2025-10-09 Vistagen Therapeutics, Inc. Treatment of dysmenorrhea

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1158966B (de) * 1961-04-29 1963-12-12 Schering Ag Verfahren zur Herstellung von 6-Chlor-1, 2ª‡-methylen-í¸-17ª‡-hydroxyprogesteronestern
US6140316A (en) * 1991-01-07 2000-10-31 Pherin Corporation Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions
US5303703A (en) * 1991-10-03 1994-04-19 Pherin Corporation Combined neuroepithelial sample delivery electrode device and methods of using same
US5563131A (en) * 1994-08-04 1996-10-08 Pherin Corporation Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US6066627A (en) * 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
US5994333A (en) * 1994-08-04 1999-11-30 Pherin Corporation Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US6057439A (en) 1994-08-04 2000-05-02 Pherin Corporation Steroids as neurochemical stimulators of the VNO to alleviate symptoms of PMS and anxiety
US5792757A (en) * 1994-08-04 1998-08-11 Pherin Pharmaceuticals 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
US6117860A (en) * 1994-08-04 2000-09-12 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to treat paroxistic tachycardia
US6331534B1 (en) * 1994-08-04 2001-12-18 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to alleviate pain
DE69736833T2 (de) * 1996-07-23 2007-05-24 Pherin Pharmaceuticals, Inc., Menlo Park Steroide als neurochemische stimulatoren des nasenraumes zur linderung der prämenstrualen symptome
US6165504A (en) * 1998-09-23 2000-12-26 Barr Laboratories, Inc. Methods for treating hot flashes and improving the quality of life of castrated prostatic cancer patients
US6613758B1 (en) 1999-04-02 2003-09-02 Barr Laboratories, Inc. Method for treating osteoporosis in castrated prostatic cancer patients
WO2000059920A2 (en) * 1999-04-06 2000-10-12 Akzo Nobel N.V. Orally active 7.alpha.-alkyl androgens
US20030045514A1 (en) * 2001-05-03 2003-03-06 Louis Monti 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors
US7482029B2 (en) * 2005-04-01 2009-01-27 Bionovo, Inc. Composition for treatment of menopause
RS20080200A (sr) * 2005-11-14 2009-07-15 Rinat Neuroscience Corp., Antagonistička antitela usmerena protiv kalcitonina, peptida povezanog sa genom, i postupak njihovog korišćenja
US20080293683A1 (en) 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Hot flushes;Vered Stearns et al;《the lancet》;2002;第36卷(第7期);第1854-1855页 *

Also Published As

Publication number Publication date
EP2278880A4 (en) 2011-08-10
BRPI0910637A2 (pt) 2015-07-28
KR20110014147A (ko) 2011-02-10
HK1157142A1 (en) 2012-06-29
WO2009126825A1 (en) 2009-10-15
US8431559B2 (en) 2013-04-30
DK2278880T3 (da) 2012-11-12
JP5524177B2 (ja) 2014-06-18
JP2011518136A (ja) 2011-06-23
US20090258040A1 (en) 2009-10-15
EP2278880A1 (en) 2011-02-02
KR101602802B1 (ko) 2016-03-11
US20120108558A1 (en) 2012-05-03
EP2278880B1 (en) 2012-10-10
AU2009234159A1 (en) 2009-10-15
MX2010011063A (es) 2010-11-22
AU2009234159B2 (en) 2013-12-19
CN102056484A (zh) 2011-05-11

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