CN102047906A - Chlorantraniliprole and profenofos compound pesticide - Google Patents

Abstract

The invention provides a chlorantraniliprole and profenofos compound pesticide, belonging to the technical field of compound pesticides. The pesticide is characterized by comprising the following substances in percentage by weight: 0.3 to 3.0 percent of chlorantraniliprole, and 30.0 to 36.0 percent of profenofos. The compound pesticide has the co-toxicity coefficient on cnaphalocrocis medinalis of between 351.1 and 477.1, has remarkable synergic effect, and has good control and prevention effect on the cnaphalocrocis medinalis, striped rice borer and other rice Lepidoptera pests. The compound pesticide has wide poisoning and insecticidal spectrum, good quick action and persistence and low production cost which is reduced by 50 percent compared with that of the pesticide singly using the chlorantraniliprole.

Description

Rynaxypyr and Profenofos Recompounded pesticide

Technical field

The invention belongs to technical field of compounded pesticide, be specially Rynaxypyr and Profenofos Recompounded pesticide.

Background technology

Paddy rice is the principal item in China cereal crops, and cultivated area is big, and disease, worm, crop smothering kind are many, and harm is heavy.According to agricultural sector statistics, every year due to illness, harm such as worm, grass, production loss reaches 20～30%.The employed agricultural chemicals quantity of disease, worm, crop smothering on the control paddy rice accounts for about 50% of China's agricultural chemicals year usage amount.Area is controlled to the medicine of rice grub in the whole nation, and about 1,200,000,000 mu, insect outbreak year medicine is controlled area can be bigger throughout the year.

The pesticide species of control paddy rice primary pest, as prevent and treat rice leaf roller, for many years, use desinsection list, chlopyrifos more, nearly 3-5 uses medicaments such as Avermectin, Affirm (Merck Co.) hydrochloride, and the large area control of rice leaf roller has been reached good effect, but owing to develop immunity to drugs after using for many years, control efficiency descends year by year.In recent years introduce medicaments such as indenes worm prestige that du pont company produces, Rynaxypyr, the lepidoptera pest on the control paddy rice, dosage is few, and preventive effect is good, but the pesticide price height, large tracts of land is promoted the use of also certain difficulty.And for example prevent and treat the snout moth's larva of rice, rice-stem borer especially, once large tracts of land is used agricultural chemicals such as desinsection list, dimehypo, Hostathion, and all because of pesticide resistance produces, preventive effect descends.After use the relevant agricultural chemicals of fluorine worm nitrile (sharp strength spy) that Bayer A.G produces and insect hormone class such as flufenoxuron etc. instead, all because of bigger to the influence of useful aquatic animals such as fish, shrimp, honeybee and insect, order to stop using on rice crop in the Ministry of Agriculture in 2009, medicament uses so that cause the control snout moth's larva of rice not have preferably.In recent years promote medicaments such as Rynaxypyr, also higher because of price above-mentioned, use and be difficult to large tracts of land.

(Chlorantraniliprole, the registrar entitling: it is wide Rynaxypyr) to have another name called health for the English common name of Rynaxypyr.Be a kind of aminobenzoic two acyl insecticides that du pont company is produced in recent years and promoted.Pure product outward appearance is a white crystals, proportion (liquid is required) 1.507g/ml, 208～210 ℃ of fusing points.330 ℃ of decomposition temperatures, vapour pressure (20～25 ℃) 6.3 * 1012pa, solvability (20～25 ℃ of g/ml): water 1.023, acetone 3.446, methyl alcohol 1.714, acetonitrile 0.711, acetate, ethyl ester 1.144.Rynaxypyr has unique insecticidal mechanism, can efficiently activate insect ryania (muscle) acceptor.Excessively discharge the calcium ion in the intracellular calcium store, cause the insect paralysis dead.Active high to the larva of lepidoptera pest, insecticidal spectrum is wide, holds the characteristics such as good of imitating.Rynaxypyr at present registered on the paddy rice primary pest as rice leaf roller, striped rice borer, paddy stem borer, pink rice borer, rice gall midge, Lissorhoptrus oryzophilus Kuschel, rice water resembled good control efficiency also arranged.This agricultural chemicals belongs to little poison level, and is also as safe as a house to the useful insect in rice field, fish, shrimp.

Profenofos (Protenofos) has another name called bromine chlorine phosphorus, many worms phosphorus.Chemical formula: O-(4-bromo-2-chlorphenyl)-O-ethyl-S-propyl group-thiophosphate.Dissolve in organic solvents such as methyl alcohol, acetone, ether, chloroform, solvability is 20 milliliters/liter in water.Medium to animal toxicity.High to birds, fish.Insect had tag, stomach poison function.Be mainly used in the control cotton, crop pests such as water paddy and wheat class.In China's large-scale production and application, can be by directly buying on the market.

In order to improve China to the relevant pesticide species of large-scale production control efficiency to rice grub, reduce and introduce the market price of pesticide species preferably recently, reduction is to the pollution of environment, if adopt China that certain production scale, the lower-cost agricultural chemicals of now using are arranged at present,, carry out reasonably composite with Rynaxypyr as pesticide species such as Profenofos, through screening test, the tangible composition of selective advance strengthens quick-acting, and reducing pesticide cost is the key of Recompounded pesticide.

Summary of the invention

At the above-mentioned problems in the prior art, the objective of the invention is to design provides the wider Rynaxypyr of a kind of poisoning, insecticidal spectrum and the technical scheme of Profenofos Recompounded pesticide, its quick-acting, lasting effect are good, and production cost is low, and is good to the control efficiency of paddy rice lepidoptera pest.

Described Rynaxypyr and Profenofos Recompounded pesticide is characterized in that containing the following material of weight percentage: chlorine worm formamide 0.3～3.0%, Profenofos 30.0～36.0%.

Described Rynaxypyr and Profenofos Recompounded pesticide, the content that it is characterized in that chlorine worm formamide is 0.4～2.5%, the content of Profenofos is 33.0～35.5%.

Described Rynaxypyr and Profenofos Recompounded pesticide, the content that it is characterized in that chlorine worm formamide is 0.5～2.0%, the content of Profenofos is 34.5～35.0%.

Described Rynaxypyr and Profenofos Recompounded pesticide, according to its purposes, can process multiple formulation such as colloidal suspending agent, add diffusant, wetting agent, binding agent, filler etc. by former medicine and make, water dispersant adds bleeding agent, diffusant, wetting agent, binding agent, filler etc. by former medicine and makes.The production technology that specifically is mixed and usual auxiliaries all belong to existing known technology, do not repeat them here.

Above-mentioned Rynaxypyr and Profenofos Recompounded pesticide reach 351.1-477.1 to the co-toxicity coefficient of rice leaf roller, and very obvious synergistic effect is arranged, and be good to the control efficiency of paddy rice lepidoptera pests such as rice leaf roller, striped rice borer.This Recompounded pesticide is poisoned, insecticidal spectrum is wider, and quick-acting, lasting effect are good, and production cost is low, reduces by 50% than single with the Rynaxypyr price.

Proportioning in the present patent application is the weight percentage of the pure material of active ingredient.

Embodiment

Below the invention will be further described by specific embodiment, and further specify beneficial effect of the present invention in conjunction with corresponding test.

Prescription one: Rynaxypyr 0.5%, Profenofos 35.5%.

Prescription two: Rynaxypyr 1.0%, Profenofos 35.0%.

Prescription three: Rynaxypyr 1.5%, Profenofos 34.5%.

Prescription four: Rynaxypyr 2.0%, Profenofos 34.0%.

Prescription five: Rynaxypyr 2.5%, Profenofos 33.0%.

Test one. the Recompounded pesticide of above-mentioned prescription is to the proportioning screening of paddy rice rice leaf roller.

1 experimental condition

1.1 for trying target: rice leaf roller ( Cnaphalocrocis medinalis) the 4-5 instar larvae.

1.2 raising situation: in about August 10, contained the phase land for growing field crops rice leaf roller moth appearance, the adult that pounces on a large amount of emergence in the dusk net is put into the raising garden of solarium and (raises garden plantation sense worm kind TN1, be the shooting stage), allow it lay eggs, hatching, treat that larvae development to 4-5 length of time, wins killed leaf roll, stand-by in indoor stripping worm.

2 experimental scheme

2.1 reagent

2.1.1 test medicine: 96.45% Rynaxypyr reason Zhejiang Shenghua Biok Biology Co., Ltd. provides, and 50% Profenofos missible oil is just reaching earlier crop protection Co., Ltd by Switzerland and producing, provides.

2.1.2 medicament preparation: adopt N.N-dimethyl formamide (D.M.F) to make solvent, add emulsifier, be configured to 10% Rynaxypyr missible oil and Profenofos 50% missible oil.

2.1.3 blank (CK): adopt N.N-dimethyl formamide (D.M.F) 3000 times of liquid (33.3mg/L) to make blank.

2.2 handle for examination

2.2.1 dosage setting

According to preliminary experiment, larva dead 90% and about 20% dosage: it is 3.1250-50.0000mg/L that Rynaxypyr is provided with 5 geometric ratio dosage, and the dosage of Profenofos is set to 5 geometric ratio dosage 50.0000-800.0000mg/L.Blank D.M.F is 33.3mg/L.

2.2.2 test repeats: each agricultural chemicals and mixture amount proportioning test are arranged to series concentration, and each concentration is provided with 4 repetitions.About 10 of each reprocessing rice leaf roller 4-5 instar larvaes.

3. test method: with reference to the agricultural industry criteria NY/T 1154.7-2006 of the People's Republic of China (PRC).Adopt dip method.

4. data statistics and analysis: the check result of each medicament and mixture sees Table 1-7.Test data machine DPS software systems is as calculated handled, and obtains LC50, LC95, toxicity regression line and 95% confidence interval of each medicament, and measurement result sees Table 8.

 

Table 1 Rynaxypyr is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae table as a result

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				50.0000	40	37	92.5
25.0000	40	33	82.5
				12.5000	40	27	67.5
6.2500	40	23	57.5
				3.1250	40	15	37.5
CK	40	1	2.5

Table 2 Profenofos is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae table as a result

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				800.0000	38	30	78.9
400.0000	40	24	60.0
				200.0000	40	18	45.0
100.0000	40	12	30.0
				50.0000	40	6	15.0
CK	40	4	10.0

Table 3 36% Rynaxypyr Profenofos mixed agent (prescription 1) is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				360.0000	40	34	85.0
180.0000	40	28	70.0
				90.0000	40	24	60.0
45.0000	40	22	55.0
				22.5000	40	16	40.0
CK	40	4	10.0

Table 4 36% Rynaxypyr Profenofos mixed agent (prescription 2) is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				360.0000	42	36	85.7
180.0000	40	30	75.0
				90.0000	40	24	60.0

45.0000	40	22	55.0
				22.5000	40	18	45.0
CK	40	4	10.0

Table 5 36% Rynaxypyr Profenofos mixed agent (prescription 3) is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				360.0000	40	34	85.0
180.0000	40	30	75.0
				90.0000	40	28	70.0
45.0000	40	24	60.0
				22.5000	40	20	50.0
CK	40	4	10.0

Table 6 36% Rynaxypyr Profenofos mixed agent (prescription 4) is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				360.0000	40	38	95.0
180.0000	40	36	90.0
				90.0000	40	28	70.0
45.0000	40	26	65.0
				22.5000	40	22	55.0
CK	40	4	10.0

Table 7 36% Rynaxypyr Profenofos mixed agent (prescription 5) is to the test of pesticide effectiveness of rice leaf roller 4-5 instar larvae

Dosage (mg/L)	The examination borer population	Dead borer population	Lethality (%)
				360.0000	40	38	95.0
180.0000	40	32	80.0
				90.0000	40	30	75.0
45.0000	40	26	65.0
				22.5000	40	24	60.0
CK	40	4	10.0

Table 8 Rynaxypyr Profenofos mixture is to the toxicity test of rice leaf roller table as a result

Medicament	LC50（mg/L）	The toxicity regression curve	Co-toxicity coefficient
				Rynaxypyr	5.4565	Y=3.9546+1.4186X	?
Profenofos	309.1844	Y=0.6708+1.7385X	?
				36% Rynaxypyr Profenofos mixture (prescription 1)	56.1072	Y=3.1541+1.0554X	388.6
36% Rynaxypyr Profenofos mixture (prescription 2)	47.9667	Y=3.2531+1.0392X	351.1
				36% Rynaxypyr Profenofos mixture (prescription 3)	31.894	Y=3.6763+0.8803X	430.1
36% Rynaxypyr Profenofos mixture (prescription 4)	27.0772	Y=3.1253+1.3086X	427.3
				36% Rynaxypyr Profenofos mixture (prescription 5)	20.9703	Y=3.6500+1.0215X	477.1

Result of the test shows: the co-toxicity coefficient of the various proportionings of 36% Rynaxypyr Profenofos mixture is all greater than 120, and showing has very obvious synergistic effect.Wherein the co-toxicity coefficient maximum of 36% Rynaxypyr Profenofos mixture (prescription 5) is considered from production cost and drug effect, and prescription 1, prescription 2 can be used as prioritization scheme and select.

Test two. the field control effectiveness test of the Recompounded pesticide control rice leaf roller of above-mentioned prescription, control the results are shown in Table 9.Be the reliability of checking proportioning screening, carried out field controling test in July, 2009 on a season hybrid rice.

1. the kind and the consumption of field reagent test:

1) 36% Rynaxypyr Profenofos mixture (prescription 2) mu consumption, 100 grams;

2) 20% Rynaxypyr colloidal suspending agent mu consumption, 20 grams;

3) 50% Profenofos missible oil mu consumption, 100 grams;

(4) blank.

2, method: adopt the field sub-district to be set, triplicate.Respectively investigate leaf roll behind the spray medicine in 3 days and 7 days and live borer population once, calculate leaf roll control efficiency and the worm alive rate that goes down.

Result of the test shows: 36% Rynaxypyr Profenofos (prescription 2) mixed agent missible oil, and mu restrains with 100, and the leaf roll control efficiency of 7 days investigation prevention rice leaf roller is 69.3% behind the medicine, and the worm rate of going down of living is 93.0%.One of assembly medicament 200 gram/kilogram Rynaxypyr mus are with the leaf roll control efficiency 78.7% of 20 grams, and the worm that the lives rate that goes down is low by 97.1%, and 2 500 gram/kilogram Profenofos mus of assembly medicament are with the 100 leaf roll control efficiency 36.2% that restrain, the worm alive rate 51.3% that goes down.Existing two rice leaf roller larvae peaks, (July 8) field when main cause that the leaf roll control efficiency is on the low side is the experimental field dispenser, last peak larva 2-3 length of time, caused the leaf roll of some, back one peak larva is a leaf roll at the beginning of 1-2 age, for this reason from the control efficiency of leaf roll rate, the leaf roll that the first larva peak causes can't recover, so control efficiency is on the low side, and control efficiency that can't the actual response medicament.In the case, the larva rate that goes down of living has reflected the control efficiency of medicament comparatively truly.But from the worm that the lives rate mixed agent (prescription 2) that goes down is 93%, and Rynaxypyr is 97.1%, and Profenofos is 51.3%, shows that mixed agent has the better prevention effect.After the two medicament dispensers of mixed agent and composition, paddy growth is normal, and no symptom of chemical damage takes place.

With fill a prescription 1 and prescription 3-5 carry out the field control effectiveness test of rice leaf roller, also can reach and the 2 similar test effects of filling a prescription.

Test three. the field control effectiveness test of the Recompounded pesticide control striped rice borer of above-mentioned prescription, control the results are shown in Table 10.Be the control efficiency of textual criticism Rynaxypyr Profenofos mixture to striped rice borer, carried out the test of pesticide effectiveness in morning in the rice field in May, 2010.

1. field reagent kind and consumption:

1) 36% Rynaxypyr Profenofos mixture (prescription 2) mu consumption, 100 grams;

2) 20% Rynaxypyr colloidal suspending agent mu consumption, 10 grams;

3) 50% Profenofos missible oil mu consumption, 100 grams;

4) blank.

2, method: adopt the field that the sub-district is set, triplicate behind the spray medicine 24 days, when Chilo spp larvae was grown to 5 length of times, when the withered heart seedling of causing harm in the field is basicly stable, carries out withered heart rate investigation.

Result of the test shows: % Rynaxypyr Profenofos mixed agent (prescription 2), and mu restrains with 100, and average withered heart rate is 0.67%, and control efficiency is 97.0%; All the control efficiency than the single agent of two contrasts is good.36% Rynaxypyr Profenofos mixed agent (prescription 2) mu restrains with 100, the content of Rynaxypyr is 1 gram, comparison is 2 grams according to medicament 200 gram/kilogram Rynaxypyr mus with 10 content that restrain, and for this reason, the comparison of mixed agent mu with medicament pesticide cost will reduce by 50% according to medicament.Mixed agent and two single agent applying areas, paddy growth is normal, and no symptom of chemical damage takes place.With fill a prescription 1 and prescription 3-5 carry out the field control effectiveness test of striped rice borer, also can reach and the 2 similar test effects of filling a prescription.

Claims (3)

1. Rynaxypyr and Profenofos Recompounded pesticide is characterized in that containing the following material of weight percentage: chlorine worm formamide 0.3～3.0%, Profenofos 30.0～36.0%.

2. Rynaxypyr as claimed in claim 1 and Profenofos Recompounded pesticide, the content that it is characterized in that chlorine worm formamide is 0.4～2.5%, the content of Profenofos is 33.0～35.5%.

3. Rynaxypyr as claimed in claim 1 and Profenofos Recompounded pesticide, the content that it is characterized in that chlorine worm formamide is 0.5～2.0%, the content of Profenofos is 34.5～35.0%.