CN101589722A - Insecticide composition containing chlorantraniliprole, preparation method and application thereof - Google Patents

Insecticide composition containing chlorantraniliprole, preparation method and application thereof Download PDF

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CN101589722A
CN101589722A CN 200910069468 CN200910069468A CN101589722A CN 101589722 A CN101589722 A CN 101589722A CN 200910069468 CN200910069468 CN 200910069468 CN 200910069468 A CN200910069468 A CN 200910069468A CN 101589722 A CN101589722 A CN 101589722A
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chlorantraniliprole
composition
code
insecticides
flufenoxuron
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CN 200910069468
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国丹丹
张海科
唤 王
娜 米
范志金
晖 赵
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南开大学
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Abstract

The invention relates to a pesticide composition, in particular to an insecticide composition. The composition comprises chlorantraniliprole with synergistic effective dose, abamectin or emamectin benzoate, and one of cyhalothrin, dursban, diazinon, acetamiprid, cypermethrin, alpha cypermethrin, thiamethoxam, thiacloprid, fenvalerate, propargite, diafenthiuron, benfuracarb, azocyclotin, buprofezin, ethofenprox, phonamiphos, fipronil, flufenoxuron, monosultap, dimehypo, imidacloprid, flufenoxuron, chlorfluazuron, pleocidin and tebufenozide, wherein the mass percentage of the three compositions is that: the chlorantraniliprole is 1 to 35 percent, the abamectin or the emamectin benzoate is 1 to 10 percent, and any one of the insecticides is 1 to 50 percent. The invention discloses a process for processing the compositions and application of the compositions in preparing insecticides for controlling agricultural, forestry and gardening insect pests.

Description

一种含氯虫苯甲酰胺的杀虫剂组合物及其制备方法和用途 Pesticidal composition and method for preparing a chlorine-containing and uses of insect benzamide

技术领域 FIELD

本发明的技术方案涉及含杀虫剂组合物,具体涉及含氯虫苯甲酰胺的杀虫组合物及其制备方法和在农业领域、园艺领域以及林业领域中的用途。 Aspect of the present invention relates to a pesticide-containing composition, in particular relates to pesticidal compositions and method for preparing chlorine insects benzamide and use in agriculture, horticulture and forestry field.

背景技术 Background technique

20世纪中期,美国天然物质专家Penick等在南美大枫子科灌木尼亚那(Ryania speciosa)中提取出了鱼尼汀,到鱼尼汀中活性更高的物质鱼尼汀碱(ryanodine)的发现,此类化合物对鳞翅目害虫十分有效,并通过作用于鱼尼汀受体(ryanodine receptor)控制钙离子释放通道,引起虫体收缩进而导致死亡;但此类物质对人畜的毒性很大,可引起哺乳动物僵直性麻痹,因而相关的合成开发与推广应用工作一直受到限制,20世纪90年代,人们随着对鱼尼汀受体结构的深入研究,目前已发现两类化合物最具有代表性,即邻苯二甲酰胺类(phthalic acid diamides)和邻甲酰氨基苯甲酰胺类(anthranilic diamides),近期日本农药公司、拜耳公司和杜邦公司发现开发的两个广谱的鱼尼汀受体结构的合成杀虫剂氟虫酰胺和氯虫酰胺与鱼尼汀碱具有相同的作用特性,不仅保持对害虫有优异的活性,而且对哺 Mid-20th century, the United States and other natural substances extracted Penick expert in South American shrub Virginia maple branch that (Ryania speciosa) out of the ryanodine to the ryanodine higher active substance ryanodine base (ryanodine) of They found that such a compound is very effective to lepidopterous pests, and calcium ions by acting on the control ryanodine receptor (ryanodine receptor) release channel, leading to the death of the contraction caused by parasites; but it is very toxic to humans and animals such substances can cause paralysis in mammals stiffness, thus related to synthesis development and application work has been limited, in the 1990s, people with in-depth study of the structure of the ryanodine receptor, has been found classes of compounds most representative resistance, i.e., phthalic acid amides (phthalic acid diamides) and o-formylamino-benzamide (anthranilic diamides), Japan recently pesticide, Bayer and Du Pont found that two of the broad spectrum developed by ryanodine flubendiamide synthetic pesticides and chlorantraniliprole ryanodine structure with a base having the same effect characteristics, not only to maintain excellent activity against pests, but also for feeding 乳动物也非常安全。 Animal milk is also very safe. 氟虫酰胺(flubendiamide,NNI-001)是日本农药和拜耳联合开发的邻苯二甲酰胺类杀虫剂,广泛用于防治鳞翅目害虫。 Flubendiamide (flubendiamide, NNI-001) Bayer Japan jointly developed pesticides and phthalic diamides insecticides, widely used to control lepidopteran pests. 该杀虫剂在果树、蔬菜、茶叶、玉米、水稻和棉花上叶面应用的药效试验已经完成,且毒性试验结果表明该类化合物对哺乳动物安全。 Foliar application of the pesticide efficacy trials have been done on fruit, vegetables, tea, corn, rice and cotton, and the toxicity test results show that the safety of such compounds to a mammal. 氯虫酰胺(chlorantraniloprole,RynaxypyrTM)是邻甲酰氨基苯甲酰胺类化合物中筛选出来的第一个杀虫剂,它是美国杜邦公司于2000年发现的一类新型杀虫剂。 Chlorantraniliprole (chlorantraniloprole, RynaxypyrTM) carboxamido ortho benzamides screening out the first insecticide, which is a new class of insecticides DuPont discovered in 2000. 邻甲酰氨基苯甲酰胺类和邻苯二甲酰胺类化合物对昆虫的生化作用机制相同,也是通过抑制鱼尼汀受体而发生作用;氯虫酰胺除了对各种鳞翅目昆虫表现出优异的防治效果,其防治靶标还涉及到夜蛾科、卷叶蛾科、螟蛾科、菜蛾科、鞘翅目的马铃薯叶甲和象甲以及双翅目的潜叶蝇等昆虫。 Carboxamido same benzamides and o-phthalic acid amide compounds and biochemical mechanism of action of insects, but also play a role by inhibiting the ryanodine receptor; rynaxypyr In addition to a variety of lepidopteran insects exhibit excellent control effect, it also relates to the prevention and treatment targets Noctuidae, Tortricidae, Pyralidae, plutellidae, Colorado potato beetle Coleoptera and Diptera leaf miner weevil and other insects.

氯虫苯甲酰胺具有新的作用方式,其通过昆虫鱼尼汀受体的活化达到防治害虫的目的。 Chlorantraniliprole having a new mode of action which achieve the purpose of controlling pest insects by ryanodine receptor activation. 这些受体对肌肉正常功能的发挥起着至关重要的作用。 These receptors on muscle plays a vital role to play normal function. 肌肉细胞的收缩需要细胞内源钙离子有序释放进入细胞质中,而鱼尼汀受体则是调节钙离子释放的选择性离子通道。 Contraction of muscle cells requires cell orderly release of endogenous calcium ions into the cytoplasm, whereas ryanodine receptor calcium release is adjusted selective ion channels. 氯虫苯甲酰胺与鱼尼汀受体的结合,导致细胞内源钙离子释放的失控和流失,使肌肉细胞的收缩功能难以为继。 Chlorantraniliprole bound amine with ryanodine receptor, resulting in loss of control and the loss of endogenous intracellular calcium release, so that contraction of the muscle cells unsustainable. 经氯虫苯甲酰胺处理后的害虫表现为进食迅速停止、乏力、反胃和肌肉瘫痪,直至死亡。 Performance by the pest after chlorantraniliprole treatment to stop eating quickly, fatigue, nausea and muscle paralysis, until death. 其独特的化学结构与新颖的作用方式,使之对其它杀虫剂的抗性害虫群体也具有杰出防效。 Its unique chemical structure and novel mode of action, so that other groups insecticide resistant pests have outstanding control effect. 氯虫苯甲酰胺只作用于昆虫鱼尼汀受体,因为这种受体与哺乳动物鱼尼汀受体之间存在结构性差异。 Chlorantraniliprole act only on the insect ryanodine receptor, because of structural differences between the receptor and the mammalian ryanodine receptor.

基于上述分析和专利调研,本发明创新性的以氯虫苯甲酰胺为主导的杀虫药剂与常见的杀虫剂进行组合,以此组合物进行了杀虫活性测定,对各药剂的效果进行了综合评价。 Based on the above patents and research analysis, the present invention is innovative in insecticide chlorantraniliprole led to common insecticides combined, this composition insecticidal activity assay, the effect of each agent is a comprehensive evaluation. 本发明为高效、低毒而环境友好的新农药的应用和研究开发及害虫的抗性治理提供了重要的理论依据。 The present invention is a high efficiency, low toxicity and environmentally friendly new pesticide application and research and development of pest resistance management provides an important theoretical basis.

发明内容 SUMMARY

本发明的技术方案涉及含氯虫苯甲酰胺的杀虫组合物及其制备方法和在农业领域、园艺领域以及林业领域中与农业上可接受的助剂或增效剂组合制备杀虫剂进行害虫综合治理以及抗药性治理中的应用。 Pesticidal compositions and preparation method aspect of the present invention relates to a chlorine-containing insect benzamide and with an agriculturally acceptable adjuvant or combination of pesticides synergist prepared in agriculture, horticulture and forestry areas IPM and resistance management application.

本发明解决该技术问题所采用的技术方案是:具有农业、园艺和林业杀虫活性的含氯虫苯甲酰胺与常规使用的杀虫进行组合物用于害虫的防治,本发明还确定了这些组合物的配方和制备方法及其对害虫的防治效果。 The present invention for solving the Problem The technical solution: with insecticide in agriculture, horticulture and forestry insect pesticidal activity benzamide chlorine is conventionally used for pest control composition of the present invention determines these formulation and method for preparing the composition and its control pests.

具体分为以下步骤: DETAILED divided into the following steps:

A.含氯虫苯甲酰胺的杀虫组合物的制备和加工方法 A. Preparation and processing methods benzamide chlorine insect pesticidal composition

在500毫升圆底烧瓶中加入氯虫苯甲酰胺(CT),然后加入阿维菌素(AV)或甲氨基阿维(AAV),再加入功夫菊酯、毒死蜱、地亚哝、啶虫脒、氯氰菊酯、高效氯氰菊酯、噻虫嗪、噻虫啉、氰戊菊酯、炔螨特、丁醚脲、丙硫克百威、三唑锡、噻嗪酮、醚菊酯、灭线磷、氟虫腈、氟虫脲、杀虫单、杀虫双、吡虫啉、氟虫脲、定虫隆、多杀菌素和虫酰肼(OT)中的任意一种药剂的原药或制剂,药剂的有效成分的含量的比例为:CT∶AV或AAV∶OT=(1%-35%)∶(1%-10%)∶(1%-50%)。 Add chlorantraniliprole (CT) in a 500 mL round-bottomed flask, followed by addition of avermectin (AV) or emamectin (the AAV), was added cyhalothrin, chlorpyrifos, Cartier garrulous, Acetamiprid , cypermethrin, beta-cypermethrin, thiamethoxam, thiacloprid, fenvalerate, propargite, diafenthiuron, benfuracarb, azocyclotin, buprofezin, etofenprox, ethoprophos, fluoro fipronil, flufenoxuron, monosultap, bisultap, imidacloprid, flufenoxuron, chlorfluazuron, any spinosad and tebufenozide (OT) of an agent or formulation of the original drug, active agent content ratio of the component is: CT:AV or AAV:OT = (1% -35%): (1% -10%): (1% -50%). 然后在搅拌下加入农业上可以接受的溶剂和助溶剂以及增效剂以及表面活性剂和抗冻剂等其他的组分,对加工的制剂进行冷储试验,液体制剂在0±2度放置1周观测有无沉淀析出,并测定混合有效成分的分解率。 Was then added with stirring and the solvent and cosolvent, and other components synergists surfactant and antifreeze agent agriculturally acceptable for formulation processing cold storage test, the liquid formulation is placed at 0 ± 2 ° 1 observing the presence or absence circumferential precipitate, and mixing rates of decomposition of the active ingredient.

B.本发明的含氯虫苯甲酰胺的杀虫组合物杀虫活性的测定: Measuring pesticidal activity chlorine insect pesticidal composition B. benzamide present invention:

杀虫活性的筛选方法:小菜蛾的测定采用叶片药膜法,待测样本配制成400微克/毫升到0.10微克/毫升的5个不同浓度梯度的水溶液,配制方法是取原药样本先用少量丙酮溶解,然后用0.5‰Triton-100水溶液稀释,0.5‰Triton-100水溶液为对照,每个浓度3次重复,每个重复处理10头试虫;取新鲜无污染的甘蓝叶片,在药液中浸10秒钟,于室内晾干(约2小时)后,放入直径9厘米的培养皿中,分别接入大小基本一致的小菜蛾3龄幼虫,用橡皮筋扎紧后置于小菜蛾恒温养虫室中,96小时后检查结果,以小毛笔或尖锐镊子轻触虫体,不能协调运动作为死亡。 The method of screening of pesticidal activity: Plutella measured using membrane in blade method, test samples formulated as 400 micrograms / milliliter to five different concentrations of an aqueous solution of 0.10 g / ml, the formulation method is to take samples of the original drug first with a small amount dissolved in acetone, then diluted with 0.5 ‰ Triton-100 aqueous solution, an aqueous solution of 0.5 ‰ Triton-100 as a control, each concentration of 3 replicates, each replicate process 10 test insects; fresh cabbage leaves pollution, the chemical solution after immersion for 10 seconds, dried at room (about 2 hours), placed in a petri dish of 9 cm diameter, substantially uniform size respectively connected 3rd instar larvae, Plutella xylostella with a rubber band is placed after the truss temperature insect rearing chamber, the test results after 96 hours, with a small brush or sharp forceps touch the worms, can not coordinate the movement as death. 用Excel软件进行IC 50的计算。 For IC 50 was calculated using Excel software.

本发明的有益效果是:本发明对含氯虫苯甲酰胺的杀虫组合物进行了配方筛选和杀虫活性的测定,这些组合物可以用于农业领域和林业领域以及园艺领域虫害的植物保护。 Advantageous effects of the invention are: the present invention to a chlorine-containing insect pesticidal composition were measured benzamide formulation screening and insecticidal activity, these compositions may be used for plant protection in agriculture and horticulture and forestry pests .

本发明将通过特定制备和生物活性测定实施例更加具体地说明含氯虫苯甲酰胺的杀虫组合物的加工工艺和生物活性及其应用,但所述实施例仅用于具体的说明本发明而非限制本发明,尤其是其生物活性仅仅是举例说明,而非限制本专利,具体实施方式如下: The present invention will be illustrated through specific preparation and bioassay described more specifically insects benzoyl chlorine process and its application and the biological activity of the pesticidal composition of the amine, but only for a specific embodiment of the present invention will be described not limit the invention, especially its biological activity are merely illustrative, and not to limit the present patent, the following specific embodiments:

实施例1:本发明的含氯虫苯甲酰胺的杀虫组合物的加工工艺和稳定性 Example 1: process stability and chlorine present invention benzamide insect pesticidal composition

本发明的含1,2,3-噻二唑活性基团的双酰肼衍生物与常见农药的混合制剂加工工艺见表1,具体的方法是:在500毫升圆底烧瓶中加入氯虫苯甲酰胺(CT),然后加入阿维菌素(AV)或甲氨基阿维(AAV),再加入功夫菊酯、毒死蜱、地亚哝、啶虫脒、氯氰菊酯、高效氯氰菊酯、噻虫嗪、噻虫啉、氰戊菊酯、炔螨特、丁醚脲、丙硫克百威、三唑锡、噻嗪酮、醚菊酯、灭线磷、氟虫腈、氟虫脲、杀虫单、杀虫双、吡虫啉、氟虫脲、定虫隆、多杀菌素和虫酰肼(OT)中的任意一种药剂的原药或制剂,药剂的有效成分的含量的比例为:CT∶AV或AAV∶OT=(1%-35%)∶(1%-10%)∶(1%-50%)。 Process mixed formulations in Table 1,2,3-thiadiazole bis hydrazide reactive group-containing derivative of the present invention with a common pesticide, specific method is: Add chlorantraniliprole benzene in a 500 ml round-bottomed flask carboxamide (CT), followed by addition of avermectin (AV) or emamectin (the AAV), was added cyhalothrin, chlorpyrifos, Cartier garrulous, acetamiprid, cypermethrin, beta-cypermethrin, thiamethoxam, thiophene thiacloprid, fenvalerate, propargite, diafenthiuron, benfuracarb, azocyclotin, buprofezin, etofenprox, ethoprophos, fipronil, flufenoxuron, monosultap, bisultap, imidacloprid, flufenoxuron, chlorfluazuron a content of the original drug or active ingredient formulation, any drug agent spinosad and tebufenozide (OT) in a ratio of: CT:AV or AAV:OT = (1% -35%): (1% -10%): (1% -50%). 然后在搅拌下加入农业上可以接受的溶剂和助溶剂以及增效剂以及表面活性剂、抗冻剂、稳定剂、增稠剂或渗透剂等其他的组分。 It was then added with stirring and the other components of the solvent and co-solvent, and a surfactant synergist, antifreeze agents, stabilizers, thickeners and the like, or an agriculturally acceptable penetrant. 加工的剂型有水乳剂、微乳剂、油悬浮剂、油剂、用农药包衣的种子、可溶性浓剂、水分散性粒剂等。 Processed forms water emulsions, microemulsions, oil suspensions, oil, seed coated with a pesticide, soluble concentrate, water dispersible granules or the like. 表1可见,对加工的制剂进行冷储试验,制剂在0±2度放置1周无沉淀析出,所有制剂储存放置前后的药剂药效无显著差异,混合有效成分的分解率在5%以内,说明药剂稳定性合格。 Table 1, formulations processing cold storage test, the formulation for one week without precipitation at 0 ± 2 °, the drug efficacy before and after all formulations stored placing no significant difference in the decomposition rate of mixing an active ingredient within 5%, Description pharmaceutical stability qualified.

实施例2:含氯虫苯甲酰胺的杀虫组合物的杀虫活性 Example 2: Insecticidal activity of the chlorine-containing benzamide insect pesticidal composition

生物测定结果表明,本发明中的含氯虫苯甲酰胺的杀虫组合物对小菜蛾均有很好的杀虫活性,比单剂活性有显著的提高,具有增效作用;测定结果的IC 50见(表2),具体的测定结果见表3。 The bioassay results showed that chlorine insects benzamide in the present invention are pesticidal compositions against Plutella good pesticidal activity, significantly higher than the activity of a single dose, have a synergistic effect; measurement result of the IC see 50 (table 2), the specific measurement results are shown in table 3.

5%氯虫苯甲酰胺乳剂对小菜蛾的致死中浓度为0.46μg/mL,2%阿维菌素乳剂对小菜蛾的致死中浓度为0.94μg/mL,0.5%甲维盐乳油对小菜蛾的致死中浓度为0.28μg/mL,2.5%功夫菊酯乳剂对小菜蛾的致死中浓度为179.9μg/mL,5.5%阿维-功夫-氯虫苯甲酰胺乳剂对小菜蛾的致死中浓度为4.04μg/mL,4%甲维盐-功夫-氯虫苯甲酰胺乳剂对小菜蛾的致死中浓度为1.64μg/mL,因此,这六种杀虫药剂都是非常好的防治小菜蛾的农药,其中氯虫苯甲酰胺及其混剂是最新的高效的防治鳞翅目害虫的药剂。 5% emulsion of chlorantraniliprole Plutella lethal concentration of 0.46μg / mL, 2% Avermectin Emulsion Plutella lethal concentration of 0.94μg / mL, 0.5% emamectin benzoate against Plutella EC the lethal concentration of 0.28μg / mL, 2.5% on emulsion cyhalothrin lethal concentration of Plutella 179.9μg / mL, 5.5% avermectin - Kung Fu - chlorantraniliprole lethal concentration of emulsion of Plutella xylostella 4.04μg / mL, 4% emamectin - Kung Fu - chlorantraniliprole emulsion on Plutella lethal concentration of 1.64μg / mL, and therefore, these six are very good insecticide pesticides against Plutella wherein chlorantraniliprole and mixtures agent is an agent effective date lepidopteran pests.

实施例3:含氯虫苯甲酰胺的杀虫组合物在防治农业和林业及园艺植物虫害中的应用 Example 3: Application of chlorine benzamide insect pesticidal composition for controlling agricultural and forestry pests in horticultural plants and

本发明的所有含氯虫苯甲酰胺的杀虫组合物可直接兑水后喷雾,其制剂中包含农业上可以接受的溶剂和乳化剂以及助溶剂,主要的剂型包括可分散浓剂、种子处理乳剂、水乳剂、微乳剂、油悬浮剂、油剂、浓悬浮剂、悬乳剂、水溶性粒剂、可溶性浓剂;可以防治的虫害有棉铃虫、红蜘蛛、粉虱、蚜虫、叶蝉、蓟马、线虫、黏虫、烟青虫、棉铃虫、红铃虫、食心虫、菜青虫、小菜蛾、甜菜夜蛾、螟虫、飞虱、蝽象和飞虱以及蚊蝇等卫生害虫,防治方式同时也包括兼治。 Pesticidal composition may be directly watered all chlorine benzamide insects after spraying the invention which formulation comprises an agriculturally acceptable emulsifier and a solvent and co-solvent, mainly formulations include dispersible concentrates, seed treatment emulsions, aqueous emulsions, microemulsions, oil suspensions, oil, suspension concentrates, suspoemulsions, water soluble granules, soluble concentrates; preventable pests are cotton bollworm, spider mites, whitefly, aphids, leafhoppers, thrips, nematodes, armyworm, tobacco budworm, cotton bollworm, pink bollworm moth, cabbage caterpillar, diamondback moth, beet armyworm, borer, planthopper, BPH and bugs like mosquitoes and other pests, prevention and treatment simultaneously but also to rid of.

表1含氯虫苯甲酰胺的杀虫与常规农药组合物为混剂的加工方法 Table 1 chlorine insects benzamide conventional pesticides and pesticidal composition is mixed agent processing method

液体制剂组成 Liquid formulation composition 液体制剂含量(%) Liquid preparations content (%) 分解率(%) Decomposition rate (%) 氯虫苯甲酰胺(CT)+阿维菌素(AV)或甲氨基阿维(AAV)+其他杀虫药(OT) Chlorantraniliprole (CT) + abamectin (AV) or emamectin (AAV) + other insecticides (OT) CT+AAV或AV+OT=(1%-35%)+(1%-10%)+(1%-50%) CT + AAV or AV + OT = (1% -35%) + (1% -10%) + (1% -50%) 1.5%-4.5% 1.5% -4.5% 助溶剂 Co-solvent 2-8 2-8 表面活性剂 Surfactant 2-10 2-10 抗冻剂 Cryoprotectants 2-5 2-5 增效剂 Synergist 0.5-8 0.5-8 其他农业上可以接受的助剂如稳定剂或增稠剂或渗透剂 Other agriculturally acceptable adjuvants such as stabilizers or thickening agents or penetrants 1-5 1-5 甲苯(水) Toluene (water) 补足100% Make up 100%

表2六种杀虫剂对小菜蛾室内毒力测定统计结果 Table 2 six kinds of pesticides determine statistical results of the diamondback moth Toxicity

药剂 Pharmacy 毒力回归方程 Toxicity regression equation 相关系数 The correlation coefficient LC 50 (μg/mL) LC 50 (μg / mL) 95%置信区间 95% confidence interval 5%氯虫苯甲酰胺乳剂 5% emulsion chlorantraniliprole y=5.40+1.18x y = 5.40 + 1.18x 0.9929 0.9929 0.46 0.46 0.35~0.59 0.35 ~ 0.59 2%阿维菌素乳剂 2% Avermectin Emulsion y=5.03+0.97x y = 5.03 + 0.97x 0.9733 0.9733 0.94 0.94 0.68~1.27 0.68 ~ 1.27 0.5%甲维盐乳油 Emamectin Benzoate 0.5% EC y=5.88+1.59x y = 5.88 + 1.59x 0.9881 0.9881 0.28 0.28 0.23~0.34 0.23 ~ 0.34 2.5%功夫菊酯乳剂 Cyhalothrin emulsion 2.5% y=-0.12+2.27x y = -0.12 + 2.27x 0.9862 0.9862 179.9 179.9 156.3~206.9 156.3 - 206.9 5.5%阿维+功夫+氯虫苯甲酰胺 Avermectin + 5.5% + effort chlorantraniliprole y=3.92+1.77x y = 3.92 + 1.77x 0.9998 0.9998 4.04 4.04 3.39~4.81 3.39 ~ 4.81 4%甲维盐+功夫+氯虫苯甲酰胺 Emamectin benzoate + 4% + effort chlorantraniliprole y=4.62+1.76x y = 4.62 + 1.76x 0.9987 0.9987 1.64 1.64 1.37~1.94 1.37 ~ 1.94

表3本发明中的六种药剂的杀虫活性(%) Table pesticidal activity of the six kinds of three agents of the invention (%)

药剂 Pharmacy 浓度μg/mL Concentration μg / mL 药前虫数 Before the number of worm medicine 死亡虫数 Number of dead insects 死亡率(%) mortality rate(%) 校正死亡率(%) Corrected mortality (%) 5%氯虫苯甲酰胺乳剂 5% emulsion chlorantraniliprole 5 5 98 98 92 92 93.9 93.9 - - 2 2 96 96 73 73 76.0 76.0 75.8 75.8 1 1 93 93 65 65 69.9 69.9 69.6 69.6 0.5 0.5 105 105 53 53 50.5 50.5 50.0 50.0 0.1 0.1 102 102 23 twenty three 22.5 22.5 21.8 21.8 CK CK 102 102 1 1 - - - - 2%阿维菌素乳剂EC 2% Avermectin Emulsion EC 5 5 104 104 88 88 84.6 84.6 - - 2 2 113 113 71 71 62.8 62.8 62.5 62.5 1 1 107 107 60 60 56.1 56.1 55.6 55.6 0.5 0.5 94 94 32 32 34.0 34.0 33.4 33.4 0.1 0.1 96 96 19 19 19.8 19.8 19.0 19.0 CK CK 102 102 1 1 - - - - 0.5%甲维盐乳油 Emamectin Benzoate 0.5% EC 2 2 109 109 91 91 83.5 83.5 - - 1 1 92 92 76 76 82.6 82.6 82.4 82.4 0.5 0.5 98 98 61 61 62.2 62.2 61.9 61.9 0.1 0.1 101 101 30 30 29.7 29.7 29.0 29.0 0.05 0.05 110 110 11 11 10.0 10.0 9.1 9.1 CK CK 102 102 1 1 - - - - 2.5%功夫菊酯乳剂 Cyhalothrin emulsion 2.5% 400 400 95 95 75 75 78.9 78.9 78.7 78.7 200 200 103 103 59 59 57.3 57.3 56.9 56.9 100 100 115 115 27 27 23.5 23.5 22.7 22.7 50 50 91 91 13 13 14.3 14.3 13.4 13.4 25 25 95 95 6 6 6.3 6.3 - - CK CK 102 102 1 1 - - - - 5.5%阿维+功夫+氯虫苯甲酰胺乳剂 Avermectin + 5.5% + effort emulsion chlorantraniliprole 10 10 114 114 87 87 76.3 76.3 76.1 76.1 5 5 96 96 54 54 56.3 56.3 55.8 55.8 2 2 99 99 30 30 30.3 30.3 29.6 29.6 1 1 100 100 15 15 15.0 15.0 14.2 14.2 0.5 0.5 97 97 5 5 5.2 5.2 CK CK 102 102 1 1 - - - - 4%甲维盐+功夫+氯虫苯甲酰胺乳剂 Emamectin benzoate + 4% + effort emulsion chlorantraniliprole 10 10 105 105 92 92 87.7 87.7 - - 5 5 98 98 78 78 79.6 79.6 79.4 79.4 2 2 103 103 60 60 58.3 58.3 57.8 57.8 1 1 112 112 40 40 35.7 35.7 35.1 35.1 0.5 0.5 92 92 17 17 18.5 18.5 17.7 17.7 CK CK 102 102 1 1 - - - -

.

Claims (4)

1.一种杀虫剂的组合物,其中包括氯虫苯甲酰胺,代号为CT,还包括常见杀虫剂如阿维菌素:代号为AV或甲氨基阿维:代号为AAV中的一种,还包括功夫菊酯、毒死蜱、地亚哝、啶虫脒、氯氰菊酯、高效氯氰菊酯、噻虫嗪、噻虫啉、氰戊菊酯、炔螨特、丁醚脲、丙硫克百威、三唑锡、噻嗪酮、醚菊酯、灭线磷、氟虫腈、氟虫脲、杀虫单、杀虫双、吡虫啉、氟虫脲、定虫隆、多杀菌素和虫酰肼,代号为OT中的一种,组合物还包括农业上可以接受的溶剂、助剂、增效剂、抗冻剂、稳定剂、增稠剂或渗透剂。 1. A pesticidal composition which comprises chlorantraniliprole, code-named CT, further comprising a common insecticides such as abamectin: code for AV or emamectin: a code for the AAV species, further comprising cyhalothrin, chlorpyrifos, Cartier garrulous, acetamiprid, cypermethrin, beta-cypermethrin, thiamethoxam, thiacloprid, fenvalerate, propargite, diafenthiuron, benfuracarb, azocyclotin, buprofezin, etofenprox, ethoprophos, fipronil, flufenoxuron, monosultap, bisultap, imidacloprid, flufenoxuron, chlorfluazuron, spinosad and tebufenozide, as a code in the OT, the composition further comprising an agriculturally acceptable solvent, adjuvant, synergist, antifreeze agents, stabilizing agents, thickening agents or penetrants.
2.权利要求1所述的氯虫苯甲酰胺与常见杀虫剂的农药组合物的组成是组合的农药的质量比列为氯虫苯甲酰胺(CT)∶阿维菌素(AV)或甲氨基阿维(AAV)∶其他杀虫药(OT)是(1%-35%)∶(1%-10%)∶(1%-50%)。 Composition pesticidal compositions chlorantraniliprole to common insecticides according to claim 1 is the mass ratio of the combination of pesticides as chlorantraniliprole (CT): abamectin (AV) or emamectin (the AAV): other insecticides (OT) (1% -35%): (1-10%): (1-50%).
3.权利要求1所述的氯虫苯甲酰胺与常见杀虫剂的农药组合物的制剂包含溶剂和农业上可接受的乳化剂以及助溶剂制成可分散浓剂、种子处理乳剂、水乳剂、微乳剂、油悬浮剂、油剂、浓悬浮剂、悬乳剂、水溶性粒剂或可溶性浓剂。 Pesticides composition chlorantraniliprole to common insecticides according to claim 1 comprising a solvent and the agriculturally acceptable emulsifier and the co-solvent is made dispersible concentrates, emulsions for seed treatment, aqueous emulsion , microemulsions, oil suspensions, oil, suspension concentrates, suspoemulsions, water soluble granules or soluble concentrates.
4.权利要求1所述的含氯虫苯甲酰胺的杀虫组合物用于在农业害虫、园艺害虫或林业害虫杀虫的用途,防治方法采用喷雾或种子包依。 Chlorine insect pesticidal composition according to claim 1 for the use of benzamide agricultural pests, horticultural insect pests the insecticidal or forestry pests, control methods employed by spraying or seed coating.
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