CN102026633A - 1-氨基-烷基环己烷衍生物用于治疗睡眠失调 - Google Patents

1-氨基-烷基环己烷衍生物用于治疗睡眠失调 Download PDF

Info

Publication number
CN102026633A
CN102026633A CN2009801170115A CN200980117011A CN102026633A CN 102026633 A CN102026633 A CN 102026633A CN 2009801170115 A CN2009801170115 A CN 2009801170115A CN 200980117011 A CN200980117011 A CN 200980117011A CN 102026633 A CN102026633 A CN 102026633A
Authority
CN
China
Prior art keywords
neramexane
amino
day
derivative
tinnitus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801170115A
Other languages
English (en)
Chinese (zh)
Inventor
B·埃勒斯-伦兹
T·罗森比尔格
H·克鲁格
M·阿尔特豪斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merz Pharma GmbH and Co KGaA
Original Assignee
Merz Pharma GmbH and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma GmbH and Co KGaA filed Critical Merz Pharma GmbH and Co KGaA
Publication of CN102026633A publication Critical patent/CN102026633A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2009801170115A 2008-06-12 2009-06-10 1-氨基-烷基环己烷衍生物用于治疗睡眠失调 Pending CN102026633A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13178908P 2008-06-12 2008-06-12
EP08010749 2008-06-12
US61/131,789 2008-06-12
EP08010749.3 2008-06-12
PCT/EP2009/004184 WO2009149920A1 (en) 2008-06-12 2009-06-10 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders

Publications (1)

Publication Number Publication Date
CN102026633A true CN102026633A (zh) 2011-04-20

Family

ID=39721946

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801170115A Pending CN102026633A (zh) 2008-06-12 2009-06-10 1-氨基-烷基环己烷衍生物用于治疗睡眠失调

Country Status (15)

Country Link
US (1) US20110207793A1 (enExample)
EP (1) EP2315586A1 (enExample)
JP (1) JP5923305B2 (enExample)
KR (1) KR20110005909A (enExample)
CN (1) CN102026633A (enExample)
AR (1) AR074246A1 (enExample)
AU (1) AU2009256905A1 (enExample)
BR (1) BRPI0911920A2 (enExample)
CA (1) CA2722763A1 (enExample)
IL (1) IL209417A0 (enExample)
MX (1) MX2010013450A (enExample)
RU (1) RU2010154623A (enExample)
TW (1) TW201010691A (enExample)
WO (1) WO2009149920A1 (enExample)
ZA (1) ZA201007763B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106535883A (zh) * 2014-04-28 2017-03-22 杏林制药株式会社 耳鸣患者的治疗用药剂

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100052558A (ko) * 2007-09-12 2010-05-19 메르츠 파마 게엠베하 운트 코. 카가아 네라멕산을 위한 적정 패키지 및 내이 질환의 치료에서의 그의 용도
US20110294890A1 (en) * 2010-05-28 2011-12-01 Merz Pharma Gmbh & Co. Kgaa Neramexane for the treatment or prevention of inner ear disorders
CN113274365B (zh) * 2021-07-22 2021-10-22 广东科泰鼎润药业科技有限公司 雷美替胺速释缓释双释放制剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19528388A1 (de) * 1995-08-02 1997-02-06 Hans Peter Prof Dr Med Zenner Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs
US6071966A (en) * 1997-06-30 2000-06-06 Merz + Co. Gmbh & Co. 1-amino-alkylcyclohexane NMDA receptor antagonists
ES2200358T3 (es) * 1997-06-30 2004-03-01 MERZ PHARMA GMBH & CO. KGAA 1-amino-alquilciclohexanos antagonistas del receptor de nmda.
AU2003274353B2 (en) * 2002-10-24 2007-04-05 Merz Pharma Gmbh & Co. Kgaa Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors
US20070141148A1 (en) * 2005-11-30 2007-06-21 Merz Pharma Gmbh & Co. Kgaa Neramexane MR matrix tablet
JP2007246507A (ja) * 2006-02-15 2007-09-27 Kracie Seiyaku Kk 疲労の予防・治療組成物及び予防・治療方法
DE102006011922A1 (de) * 2006-03-15 2007-09-20 Uwe Stoldt Mittel zur Behandlung von Tinnitus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106535883A (zh) * 2014-04-28 2017-03-22 杏林制药株式会社 耳鸣患者的治疗用药剂

Also Published As

Publication number Publication date
RU2010154623A (ru) 2012-08-10
MX2010013450A (es) 2011-02-23
ZA201007763B (en) 2011-07-27
IL209417A0 (en) 2011-01-31
AR074246A1 (es) 2011-01-05
TW201010691A (en) 2010-03-16
JP2011522850A (ja) 2011-08-04
JP5923305B2 (ja) 2016-05-24
KR20110005909A (ko) 2011-01-19
AU2009256905A1 (en) 2009-12-17
WO2009149920A1 (en) 2009-12-17
CA2722763A1 (en) 2009-12-17
BRPI0911920A2 (pt) 2015-10-06
EP2315586A1 (en) 2011-05-04
US20110207793A1 (en) 2011-08-25

Similar Documents

Publication Publication Date Title
JP5613053B2 (ja) 耳鳴を処置するための間欠療法
CN102026633A (zh) 1-氨基-烷基环己烷衍生物用于治疗睡眠失调
JP6084931B2 (ja) ストレス又は急性聴力損失に関連する耳鳴の治療又は予防のためのネラメキサン
US20110178179A1 (en) 1-amino-alkylcyclohexane derivatives for the treatment of cognitive impairment in tinnitus
RU2446794C2 (ru) Терапия с интервалами для лечения тиннитуса
HK1154791A (en) 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders
RU2459618C2 (ru) Титрационный комплект нерамексана и его применение в лечении расстройств внутреннего уха
HK1143536A (en) Interval therapy for the treatment of tinnitus
HK1145151A (en) 1-amino-alkylcyclohexane derivatives for the treatment of cochlear tinnitus
HK1158537A (en) 1-amino-alkylcyclohexane derivatives for the treatment of cognitive impairment in tinnitus

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1154791

Country of ref document: HK

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20110420

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1154791

Country of ref document: HK