CN102026628A - 具有降低崩裂效果的口服控释片剂 - Google Patents

具有降低崩裂效果的口服控释片剂 Download PDF

Info

Publication number
CN102026628A
CN102026628A CN2009801103021A CN200980110302A CN102026628A CN 102026628 A CN102026628 A CN 102026628A CN 2009801103021 A CN2009801103021 A CN 2009801103021A CN 200980110302 A CN200980110302 A CN 200980110302A CN 102026628 A CN102026628 A CN 102026628A
Authority
CN
China
Prior art keywords
compressive layer
coating
alcohol
release
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801103021A
Other languages
English (en)
Chinese (zh)
Inventor
尼廷·巴拉昌哲·达玛惴卡瑞
亚绍瑞亚·瑞普赛·扎拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharma Advanced Research Co Ltd
Original Assignee
Sun Pharma Advanced Research Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharma Advanced Research Co Ltd filed Critical Sun Pharma Advanced Research Co Ltd
Publication of CN102026628A publication Critical patent/CN102026628A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
CN2009801103021A 2008-02-15 2009-02-16 具有降低崩裂效果的口服控释片剂 Pending CN102026628A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN339MU2008 2008-02-15
IN339/MUM/2008 2008-02-15
PCT/IN2009/000106 WO2009122431A2 (en) 2008-02-15 2009-02-16 Oral controlled release tablet

Publications (1)

Publication Number Publication Date
CN102026628A true CN102026628A (zh) 2011-04-20

Family

ID=40955347

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801103021A Pending CN102026628A (zh) 2008-02-15 2009-02-16 具有降低崩裂效果的口服控释片剂

Country Status (10)

Country Link
US (1) US20090208572A1 (enExample)
EP (1) EP2242485A4 (enExample)
JP (1) JP2011512349A (enExample)
KR (1) KR20100136967A (enExample)
CN (1) CN102026628A (enExample)
BR (1) BRPI0908114A2 (enExample)
CA (1) CA2715584A1 (enExample)
MX (1) MX2010008861A (enExample)
WO (1) WO2009122431A2 (enExample)
ZA (1) ZA201006793B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050158342A1 (en) * 2003-12-23 2005-07-21 Medimmune, Inc. Multi plasmid system for the production of influenza virus
AU2003231083A1 (en) * 2002-04-26 2003-11-10 Medimmune, Llc Multi plasmid system for the production of influenza virus
US7465456B2 (en) * 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
US7718517B2 (en) 2002-08-19 2010-05-18 Im James S Single-shot semiconductor processing system and method having various irradiation patterns
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
CA2690196A1 (en) * 2007-06-18 2008-12-24 Medimmune, Llc Influenza b viruses having alterations in the hemaglutinin polypeptide
CN102573811A (zh) 2009-06-02 2012-07-11 陶氏环球技术有限责任公司 缓释剂型
JP2013504562A (ja) * 2009-09-17 2013-02-07 カディラ・ヘルスケア・リミテッド アルコールで誘発される用量ダンピングを低減するための医薬組成物
WO2011041414A1 (en) 2009-09-30 2011-04-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
WO2012166474A1 (en) * 2011-06-01 2012-12-06 Fmc Corporation Controlled release solid dose forms
RU2018141241A (ru) 2012-11-30 2019-01-24 Экьюра Фармасьютикалз, Инк. Саморегулируемое высвобождение фармацевтического ингредиента
US9675587B2 (en) 2013-03-14 2017-06-13 Allergan Holdings Unlimited Company Opioid receptor modulator dosage formulations
JP5941117B2 (ja) * 2014-10-17 2016-06-29 ダウ グローバル テクノロジーズ エルエルシー 徐放製剤
US11103581B2 (en) 2015-08-31 2021-08-31 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
EA030138B1 (ru) * 2016-06-15 2018-06-29 Общество С Ограниченной Ответственностью "Фармадиол" Фармацевтические композиции, включающие антикоагулянт n-(5-хлорпиридин-2-ил)-2-({4-[этанимидоил(метил)амино]бензоил}амино)-5-метилбензамид
IT201800011125A1 (it) * 2018-12-14 2020-06-14 Dpl Pharma S P A Composizioni farmaceutiche orali solide comprendenti matrici monolitiche complesse per la somministrazione cronotropica di medicamenti nel tratto gastroenterico
WO2021224469A1 (en) * 2020-05-08 2021-11-11 Janssen Pharmaceutica Nv Treatments of prostate cancer with combinations of abiraterone acetate and niraparib
WO2025137498A1 (en) * 2023-12-20 2025-06-26 Areteia Therapeutics, Inc. Matrix tablets of dexpramipexole and methods of manufacturing and use thereof
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4519801A (en) * 1982-07-12 1985-05-28 Alza Corporation Osmotic device with wall comprising cellulose ether and permeability enhancer
US4693896A (en) * 1985-10-07 1987-09-15 Fmc Corporation Ethylcellulose-coated, gastric-disintegrable aspirin tablet
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US5271946A (en) * 1988-04-20 1993-12-21 Asta Pharma Aktiengesellschaft Controlled release azelastine-containing pharmaceutical compositions
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
IT1237904B (it) * 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
DE69229881T2 (de) * 1991-10-04 1999-12-09 Yoshitomi Pharmaceutical Industries, Ltd. Tablette mit verzögerter freisetzung
DE69425453T2 (de) * 1993-04-23 2001-04-12 Novartis Ag, Basel Wirkstoffabgabevorrichtung mit gesteuerter Freigabe
SK281193B6 (sk) * 1993-05-15 2001-01-18 Roche Diagnostics Gmbh Tableta so zlepšenou biodostupnosťou účinnej látky, kyseliny klodrónovej, spôsob jej výroby a použitie mikrokryštalickej celulózy
IT1264517B1 (it) * 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
US5582838A (en) * 1994-12-22 1996-12-10 Merck & Co., Inc. Controlled release drug suspension delivery device
IT1282576B1 (it) * 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
EP0951279A1 (en) * 1997-01-10 1999-10-27 Abbott Laboratories Tablet for the controlled release of active agents
US6322819B1 (en) * 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
US6706283B1 (en) * 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
WO2001047500A1 (en) * 1999-12-23 2001-07-05 Pfizer Products Inc. Hydrogel-driven drug dosage form
US6720005B1 (en) * 2000-07-07 2004-04-13 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Coated, platform-generating tablet
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
EA005537B1 (ru) * 2001-07-10 2005-04-28 Тева Фармасьютикал Индастриес Лтд. Система доставки лекарственного вещества по нулевому порядку, нулевому порядку - двухстадийной, возрастающей или убывающей доставки препарата
GB0117618D0 (en) * 2001-07-19 2001-09-12 Phoqus Ltd Pharmaceutical dosage form
ITMI20020515A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema per il rilasco controllato di uno o piu' principi attivi
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
WO2004108067A2 (en) * 2003-04-03 2004-12-16 Sun Pharmaceutical Industries Limited Programmed drug delivery system
US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
UA85850C2 (uk) * 2003-09-19 2009-03-10 Сан Фарма Адвансед Ресьорч Компані Лтд. Оральна система доставки лікарського препарату
US20060193912A1 (en) * 2005-02-28 2006-08-31 Penwest Pharmaceuticals Co. Controlled release O-desmethylvenlafaxine formulations
WO2006123364A2 (en) * 2005-03-14 2006-11-23 Sun Pharmaceutical Industries Limited Oral drug delivery system providing a coating comprising both a cellulose and a methacrylic acid derivative
AU2006254554B2 (en) * 2005-06-03 2011-11-24 Egalet Ltd A solid pharmaceutical composition with a first fraction of a dispersion medium and a second fraction of a matrix, the latter being at least partially first exposed to gastrointestinal fluids
PL116330U1 (en) * 2005-10-31 2007-04-02 Alza Corp Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
WO2007057762A2 (en) * 2005-11-16 2007-05-24 Pfizer Limited Osmotic bi-layer tablet
US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration

Also Published As

Publication number Publication date
CA2715584A1 (en) 2009-10-08
JP2011512349A (ja) 2011-04-21
KR20100136967A (ko) 2010-12-29
EP2242485A2 (en) 2010-10-27
WO2009122431A2 (en) 2009-10-08
WO2009122431A3 (en) 2010-01-07
MX2010008861A (es) 2011-02-22
EP2242485A4 (en) 2013-05-08
ZA201006793B (en) 2011-05-25
US20090208572A1 (en) 2009-08-20
BRPI0908114A2 (pt) 2015-10-06

Similar Documents

Publication Publication Date Title
CN102026628A (zh) 具有降低崩裂效果的口服控释片剂
US8535717B2 (en) Pharmaceutical composition
US8470367B2 (en) Oral drug delivery system
JP2022104916A (ja) 自己調節性の浸透性胃保持性薬物送達システム
JP5020931B2 (ja) 経口薬剤送達システム
US10226428B2 (en) Oral drug delivery system
US10213387B2 (en) Oral drug delivery system
WO2004037226A2 (en) Pharmaceutical compositions containing venlafaxine
WO2008102235A1 (en) Controlled release formulations of alfuzosin
MXPA06002994A (en) Oral drug delivery system

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20110420