CN102018743B - Chinese medicinal capsules for treating diabetes and complicating diseases and preparation method thereof - Google Patents

Chinese medicinal capsules for treating diabetes and complicating diseases and preparation method thereof Download PDF

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CN102018743B
CN102018743B CN2010105699226A CN201010569922A CN102018743B CN 102018743 B CN102018743 B CN 102018743B CN 2010105699226 A CN2010105699226 A CN 2010105699226A CN 201010569922 A CN201010569922 A CN 201010569922A CN 102018743 B CN102018743 B CN 102018743B
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diabetes
glad
chinese medicinal
take
medicine
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CN102018743A (en
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赵立明
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Abstract

The invention discloses Chinese medicinal capsules for treating diabetes and complicating diseases and a preparation method thereof. The Chinese medicinal capsules are prepared by the following raw materials and pharmaceutically acceptable auxiliary materials in percentage by weight: 8 to 16 percent of bullwhack, 40 to 60 percent of honeysuckle flower, and 30 to 50 percent of Rama. The preparation method comprises the following process flows: crushing the raw materials; adding water for extracting; filtering; adding the auxiliary materials into a filtrate; concentrating to obtain dry particles; and filling the dry particles into capsules. The diabetes is prolonged unhealed caused by stomach heat and kidney deficiency, so the bullwhack is used for tonifying the kidney, and the honeysuckle flower and the Rama are used for clearing heat and releasing toxin. The Chinese medicinal capsules have dual effects of treating hyperglycemia and hypoglycemia of the diabetes functionally and simultaneously can treat the complicating diseases caused by the diabetes.

Description

A kind of Chinese medicinal capsule for the treatment of diabetes and complication and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine formula field, specifically refer to Chinese medicine formula for the treatment of diabetes and preparation method thereof.
Background technology
TCM treatment of diabetes is moisturized with YIN nourishing, and pathogenic fire reducing is main, and is scorching because of internal organs with the diabetes-alleviating people, " more than three " due to the hyperactivity of fire caused by deficiency of YIN.
Summary of the invention
The technical problem to be solved in the present invention is the defective that overcomes existing Diabetes Mellitus Treated With Traditional Chinese Medicine and complication, and Chinese medicine capsules of a kind of brand-new prescription and preparation method thereof is provided.
In order to solve the problems of the technologies described above, the invention provides following technical scheme:
A kind of Chinese medicinal capsule for the treatment of diabetes and complication is prepared from by raw material and an amount of pharmaceutically acceptable adjuvant of weight proportion as described below: Testis Et penis Bovis seu Bubali 8%-16% (water content 5-15%), Flos Lonicerae 40%-60%, sieve 30%-50% that rubs.Further, raw material and an amount of pharmaceutically acceptable adjuvant by following weight proportion is prepared from: Testis Et penis Bovis seu Bubali 12%, Flos Lonicerae 50%, sieve rub 38%.
Its preparation technology's flow process is: with described raw material pulverizing, extracting in water filters, and adds adjuvant in the filtrate, and concentrate drying gets granule, incapsulates to get final product.
Gastric heat is suffered from a deficiency of the kidney and is caused that diabetes are prolonged not to heal, and controls with the Testis Et penis Bovis seu Bubali the kidney invigorating Flos Lonicerae, sieve heat-clearing and toxic substances removing that rubs.Functional treatment diabetes hyperglycemia, hypoglycemia double effects also can be treated the complication that diabetes cause simultaneously; 2~3 days take effect, and pure Chinese medicine (not containing western medicine composition) is refining to be formed.
The specific embodiment
Below the preferred embodiments of the present invention are described, should be appreciated that preferred embodiment described herein only is used for description and interpretation the present invention, is not intended to limit the present invention.
Embodiment 1
A kind of Chinese medicinal capsule for the treatment of diabetes and complication, be prepared from by raw material and an amount of pharmaceutically acceptable adjuvant of weight proportion as described below: Testis Et penis Bovis seu Bubali 8%, Flos Lonicerae 42%, sieve rub 50%.
Embodiment 2
A kind of Chinese medicinal capsule for the treatment of diabetes and complication, be prepared from by raw material and an amount of pharmaceutically acceptable adjuvant of weight proportion as described below: Testis Et penis Bovis seu Bubali 16%, Flos Lonicerae 54%, sieve rub 30%.
Embodiment 3
A kind of Chinese medicinal capsule for the treatment of diabetes and complication, be prepared from by raw material and an amount of pharmaceutically acceptable adjuvant of weight proportion as described below: Testis Et penis Bovis seu Bubali 12%, Flos Lonicerae 50%, sieve rub 38%.
The preparation method of the capsule of embodiment 1-3 is as follows: with prepared slices of Chinese crude drugs washing, crushed after being dried is crossed 10 mesh sieves; To expect that powder is added to the water, heating extraction 2 hours, centrifugal filtration gets filtrate 1 and filtering residue 1; Filtering residue 1 adds water, extracts 1.5 hours with method, and centrifugal filtration gets filtrate 2 and filtering residue 2; Filtering residue 2 adds water, extracts 1 hour with method, and centrifugal filtration gets filtrate 3 and filtering residue 3; Filtering residue is abandoned, and filtrate 1-3 merges, and stirs evenly, leaves standstill the clarification medicinal liquid, and filters; Filtering residue is abandoned, got filtrate, heat to 80 degrees centigrade, add flour as disintegrating agent, and concentrate drying, pulverize, behind choosing grain, granulate, incapsulate shell, making sheet attaches together to get capsule product.
Cure case:
Case one:
Name: Li Guifang
1995-3-8 patient's private prosecution: suffered from diabetes 13 years, the binocular vision is blind, blood glucose fluctuation about 13.5~16mmol/L, uncomfortable in chest, cardiopalmus in addition simultaneously, hypomnesis, giddy, numb hand and foot
Look into: edema of lower limbs, lip is dim, pale tongue, weak pulse is unable
R: glad 270 of many power, every day three times, each three, boiled water takes to advise to win and gives up alcohol and spirituosity class beverage after meal
Doctor: Zhao Liansheng
The 1995-4-10 private prosecution: after taking medicine 30 days, the binocular vision restoration, clear depending on thing, the patient requires to continue to take the sugar of having a blood test again after second course for the treatment of.
R: glad 270 of many power, instructions about how to take medicine are the same
Doctor: Zhao Liansheng
The 1995-5-13 private prosecution: conscious clinical symptom disappearance, the sugar of having a blood test has dropped to 5.2mmol/L, and whether the patient puts question to can continue to take the glad capsule of many power.Doctor's advice is won and was continued to take 100 days, to consolidate curative effect.
R: glad 270 of many power, instructions of taking is the same.(this patient took again four months subsequently)
Doctor: Zhao Liansheng
Patient address: Lanzhou Electrical Machinery Plant
Case two:
Patient's name: Wang Cuilan
The 1995-4-21 private prosecution: thirsty polydipsia, dry mouth and tougue, throat is done, frequency of micturition amount how 11 years, the time heavy when light, be in hospital every year and in many ways seek medical advice, through looking into fasting glucose≤10.8mmol/L, conscious general weakness, the lazy speech of breathing hard.
Look into: body of the tongue is light red, thin fur, and deep-slow pulse is unable
R: many power are glad, the morning, noon and afternoon three times, and each two, to take medicine 30 days (course for the treatment of), boiled water takes.Doctor's advice: taboo food alcoholic beverages, absolute prohibition is drunk.
Doctor: Zhao Liansheng
The 1995-5-26-private prosecution: thirsty after the week of taking medicine, throat is done, and fatigue and weak disappears substantially, and urine is many also take a favorable turn, and at the of that month blood glucose≤9.3mmol/L that looked in 23rd, oneself having felt has a gleam of hope.
R: glad 30 days of many power, continue to take second course for the treatment of, instructions about how to take medicine are the same.
Doctor: Zhao Liansheng
The 1995-6-27 private prosecution: sensation is own, and things are as usual, and do not have before the health when sick approximate, and the patient is reluctant to continue the sugar of having a blood test, and removes the sugar of having a blood test after continuing to take the 3rd course for the treatment of again.
R: glad 30 days medicines of many power, instructions about how to take medicine are the same
Doctor: Zhao Liansheng
The 1995-8-7 private prosecution: the blood glucose that the patient looked into July 29, glucose in urine, blood glucose≤5.2mmol/L, glucose in urine is negative
Look into: red tip of the tongue white and thin fur deep-thready pulse
R: glad 30 days medicines of many power, morning, noon and afternoon every day are individual once, and each one, instructions about how to take medicine are the same.Continue to take a course for the treatment of, sick kitchen is used for after being ill conditioning with red date porridge, as a means of consolidation
Doctor: Zhao Liansheng
Patient address: native gate pier high yield warehouse
Case three:
Patient's name: Wei Yumin
1995-7-28 private prosecution: suffered from diabetes before 5 years, all keep with insulin always, be no less than 19mmol/L when blood glucose is minimum, anasarca occurs over nearest two months, waistline sees that greatly urine is reduced, through the albumen that has urine examined +++, urine protein quantitation>305g/24n, plasma protein<20g/L, cholesterol is also high, give Western medicine, more than the intravenous injection moon, edema does not disappear, see that abdomen is wet obviously, remaining disease has no improvement.
Look into: the greasy deep-thready pulse of pale tongue moist and slippery fur is strong
R: (prescription: prescription: ten pairs of WUPI YIN plus-minuss), many power glad every day three times, each three, boiled water takes glad 180 of many power after meal, and Chinese medicine potion every day is decocted in water for oral dose.
Doctor: Zhao Liansheng
The 1995-8-20 private prosecution: sb.'s illness took a favorable turn
R: continue to take by the top
Doctor: Zhao Liansheng
The 1995-12-5 private prosecution: after taking medicine three months, conscious all feel that well through surveying routine urinalysis: urine protein is turned out cloudy, the urine egg quantitatively<0.5g/24h, it is normal that plasma protein and blood fat recover, edema ascites is moved back, sugar returns to 7.8mmol/L through having a blood test.
R: the glad continuation decrement of many power was taken three months, to consolidate curative effect.
Doctor: Zhao Liansheng
Case four
Patient: Qi Dingfeng
The 1995-9-18 private prosecution: the patient has diabetes (++ ++), has some thing more, blood glucose two to three mmol/L that just rise, and concurrent trouble andropathy (sexual impotence) again was again 3 years afterwards, blood glucose 16.7mmol/L
Look into: the profound blood glucose 16.7mmol/L of the medium thin fur red tongue of body constitution deep pulse
R: 30 days medicines of how sharp glad capsule
Doctor: Zhao Liansheng
The 1995-10-12 private prosecution: through take many power glad after, diabetes take a turn for the better to some extent, but can't eat more, plus sige does not rise, physical energy is all very abundant, sexual function also take a favorable turn.It is glad that requirement continues to take many power.
R: 30 days medicines of the glad capsule of many power
The 1995-11-12 private prosecution: recovery of melituria is very fast, and sexual function recovers also clearly, and blood glucose drops to 6.2mmol/L
Look into: deep pulse is the gentle white pale tongue of tongue surely
R: 30 days medicines of how sharp glad capsule
Doctor: Zhao Liansheng
The 1995-12-15 private prosecution: take medicine three courses for the treatment of, checked in three days through drug withdrawal, two sugar are normal
Advise: take again a course for the treatment of to consolidate
Doctor: Zhao Liansheng
Case five
Patient's name: Su Duozhi
The 1995-8-4 private prosecution: twinge is radiated to the back of the body before the heart, must not breathe hard and separates, the while in hospital sugared 13.1mmol/L that has a blood test, the trouble diabetes more than 8 years, began before 3 years to beat insulin, joined to take Chinese medicine and western medicine, also produce effect in early days, take now any medicine the state of an illness is taken a turn for the better to some extent.
Look into: tongue body is light fat, purple dark, white, slippery and moist fur, and deep-thready pulse is faint
R: Electrocardioscopy is also informed and will be come again tomorrow
Doctor: Zhao Liansheng
The 1995-8-5 private prosecution: electrocardiographic diagnosis is coronary heart disease
R: glad 180 of many power, every day three times, each two, boiled water takes after meal
Doctor: Zhao Liansheng
The 1995-9-15 private prosecution: it is two days later glad to take many power, and sensation of pricking is eased with breathing hard before the heart, feels that also whole body is strong simultaneously, blood glucose decline band≤12.1mmol/L
Look into: pale tongue thin fur the lung-pulse is profound thin
R: 180 of the glad capsules of many power.Instructions about how to take medicine are the same
Doctor: Zhao Liansheng
1995-10-15 private prosecution: conscious gun-ho, blood glucose≤9.7mmol/L
R: glad 180 of many power, instructions about how to take medicine are the same
Doctor: Zhao Liansheng
The 1995-11-20 private prosecution: conscious things are as usual, blood glucose≤5.8mmol/L
R: glad 30 days medicines of many power, once a day, each one, boiled water takes.
Doctor: Zhao Liansheng
Case six
Patient: secretary Zhao of province medicine office
Secretary Zhao of 1995-11-9 province medicine office is existing more than 5 years because suffering from diabetes, be in hospital every year, curative effect is not good enough, Chinese medicine has also been taken a lot, DeGrain, and an institute is about me and looks to secretary Zhao, because not being with medicine to go, just will economize the glad capsule portions of many profits that the chief that medicine is opened uses at seminar to secretary Zhao, a chief only assigns to seven capsules, requires a chief to take to secretary Zhao first
R: seven of the glad capsules of many power, every day three times, the morning, noon and afternoon after meal boiled water take
1995-11-12 opens the chief and tells me through the telephone, and the good results are evident after Zhao secretary took, and takes medicine two days later, energy, muscle power all are improved, and mouth is not thirsty, moist yet yet, dietary amount is all comparatively normal, requires me preparing to secretary Zhao, and the secretary of the later Chao Dynasty oneself came to get it filled and took back Tianjin New Year's Day.
Chief's phone is opened by province medicine inspecting institute: 8440660
Case seven
Patient: Ke Xingguo
1999-8-2 private prosecution: suffered from diabetes 5 years 03 months, and after blood glucose drops to 9.8mmol/L, took again any medicine all to no effect.
Look into: eutrophy, body of the tongue is light red, greasy fur, arteries and veins is profound strong
R:(patient requires examination to take 15 days), glad 90 of many power, every day three times, each two, boiled water takes
1999-10-11 private prosecution: because economic conditions are reluctant to seek medical advice outside, but through take power more than 15 days glad after, change and take the blood sugar lowering Western medicine, consciously unapprehendedly be: be to take hypoglycemic medicine not have all the time effect in the past, but after the power more than 15 days of taking is glad, the hypoglycemic medicine of taking before taking again just produces effect very much, takes since then hypoglycemic medicine after two months, and blood glucose drops to 5.2mmol/L.
Doctor: Zhao Liansheng
Jiao Jia gulf, Ke Xingguo Lanzhou
Case eight
Patient: Miu Yongdong
The 2000-9-8 private prosecution: the patient suffered from diabetes more than 8 years, and blood glucose maintains more than the 9.5mmol/L, and multi-treatment is invalid, and blood glucose can't lower all the time, was in harmony meeting in orchid, introduced through director Ma and took 180 of the glad capsules of many power, and every day three times, each two, boiled water takes
2000-10-11 tells through director Ma in generation: the patient took the glad capsule of many power after one month, and blood glucose drops to 8.7mmol/L, and proposed to continue clothes
R: glad 180 of many power, instructions about how to take medicine are the same
2000-10-30 inquires this patient through phone, the near 7.5mmol/L of patient's blood glucose
This patient is the Miu Yongdong of Lanzhou statistics bureau
Case nine
Patient's name a: Ji Xiang
The 2000-5-14 private prosecution: suffer from diabetes and had a surplus in 10 years, blood glucose is not less than 16.5mmol/L always, takes medicine through the distinguished veteran doctors of TCM treatment and all fails blood glucose is lowered
Look into: fat body of the tongue is little red, the white and thin fur deep-slow pulse
R: glad 42 of many power, every day three times, each two, examination is taken a week
The 2000-5-22 private prosecution: take many power after the glad week, blood glucose drops to 10.2mmol/L
R: glad 180 of many power, instructions about how to take medicine are the same
Doctor: Zhao Liansheng
The 2000-6-25 private prosecution: sugar has dropped to 7.2mmol/L through having a blood test
Look into: fat, the little red white and thin fur deep pulse of body of the tongue is steady
R: glad 180 of many power, instructions about how to take medicine are the same
The 2000-7-30 private prosecution: through taking many power after glad 67 days, be down to 5.4mmol/L through the sugar of having a blood test, the patient requires drug withdrawal, changes to take LIUWEI DIHUANG WAN and can freely take medicine in hospital.
The patient is that Ji Xiang is opened in seal retail department, Lanzhou
Case ten
Patient's name: Hu Youren
The 2001-8-8 private prosecution: suffer from diabetes and had a surplus in 10 years, blood glucose fluctuates between 20~25mmol/L, and glucose in urine exists ++ +~~++ ++, in the process for the treatment of diabetes, take Chinese medicine and western medicine all without positive effect, blood glucose, glucose in urine all can fall
R: glad 24 of many power, three times on the one, once two, examination is taken
The 2001-8-13 private prosecution: after examination was taken four days, below, back carbuncle was got better and is turned, and joint part is pleasant.
The patient makes by oneself and takes
R: glad 180 of many power, instructions about how to take medicine are the same
The 2001-9-11 private prosecution: the patient is 3.8mmol/L in hospital of unit fasting glucose in morning monitoring result, and conscious eyes are dry and astringent, and both feet are original sends out cold without temperature, through the rear foot of taking medicine temperature has been arranged, and the patient requires to continue to take a course for the treatment of, to consolidate curative effect
R: glad 180 of many power, every day three times, each two, take ten days after, every day twice, each two; After 20 days, every day twice, each one.
Case 11
Patient's name: Han Yushan
Swollen ascites loss of appetite serum creatinine 760 units of the sleeping silkworm eyebrow whole body of 2004-5-15 diabetes chronic renal failure uremia anuria
R: the doctor trained in Western medicine conventional therapy, dialysis biweekly
Chinese traditional treatment: glad 6 of many power, every day three times, each one, Chinese medicine Decoction for Relieving Edema plus-minus, is decocted in water for oral dose by two pairs
Doctor: Zhao Liansheng
The 2004-5-20 private prosecution: swollen see disappear, urine is arranged but amount is few
R: Chinese medicine two or five Tongas subtract, and are decocted in water for oral dose
Glad 39 of many power, every day three times, each one
Dialysis biweekly
2004-6-7 private prosecution: swell and obviously disappear, appetite is arranged
Look into: the white and slippery fur arteries and veins is profound thin
R: Chinese medicine and western medicine is the same, glad 90 of many power, and instructions about how to take medicine are the same
Doctor: Zhao Liansheng
The 2004-7-10 private prosecution: whole body is swollen to disappear, and urine is arranged and often, urine is measured about 300~400 milliliters, conscious good
R: doctor trained in Western medicine dialysis was by originally biweekly being down to one month once, Chinese medicine the same (annotating: left hospital this moment and gone home to take medicine and continue to take the glad treatment of many power)
Check serum creatinine 100 units of 2004-7-18 city hospital dialyse 30 days once, glad 90 of many power, and every day three times, each one, boiled water takes, voluntarily drug withdrawal after three months
Doctor: Zhao Liansheng
It should be noted that at last: the above only is the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment the present invention is had been described in detail, for a person skilled in the art, it still can be made amendment to the technical scheme that aforementioned each embodiment puts down in writing, and perhaps part technical characterictic wherein is equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (2)

1. Chinese medicinal capsule for the treatment of diabetes and complication is characterized in that:
Raw material and an amount of pharmaceutically acceptable adjuvant by weight proportion as described below are prepared from: Testis Et penis Bovis seu Bubali 8%-16%, Flos Lonicerae 40%-60%, sieve 30%-50% that rubs,
With described raw material pulverizing, extracting in water filters, and adds adjuvant in the filtrate, and concentrate drying gets granule, incapsulates to get final product.
2. the Chinese medicinal capsule for the treatment of diabetes according to claim 1 and complication is characterized in that:
Raw material and an amount of pharmaceutically acceptable adjuvant by following weight proportion are prepared from: Testis Et penis Bovis seu Bubali 12%, Flos Lonicerae
50%, sieve rubs 38%.
CN2010105699226A 2010-12-02 2010-12-02 Chinese medicinal capsules for treating diabetes and complicating diseases and preparation method thereof Active CN102018743B (en)

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CN102018743B true CN102018743B (en) 2013-10-23

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Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
东方旭.糖尿病的食疗谱(续9).《东方食疗与保健》.2007,(第9期),
从毒辨治糖尿病探析;潘善余;《中华中医药学刊》;20070131;第25卷(第1期);39页右栏第6-21行 *
潘善余.从毒辨治糖尿病探析.《中华中医药学刊》.2007,第25卷(第1期),
糖尿病的食疗谱(续9);东方旭;《东方食疗与保健》;20070930(第9期);34页右栏第3-8行 *

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