CN102017971A - Metconazole-containing bactericidal composition - Google Patents
Metconazole-containing bactericidal composition Download PDFInfo
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- CN102017971A CN102017971A CN201010607226XA CN201010607226A CN102017971A CN 102017971 A CN102017971 A CN 102017971A CN 201010607226X A CN201010607226X A CN 201010607226XA CN 201010607226 A CN201010607226 A CN 201010607226A CN 102017971 A CN102017971 A CN 102017971A
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- metconazole
- carbendazim
- bactericidal composition
- thiophanate
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Abstract
The invention provides a metconazole-containing bactericidal composition, which comprises an active component A and an active component B, wherein the active component A is metconazole and the active component B may be one of carbendazim, probenazole and thiophanate methyl. The carbendazim serving as the active component A accounts for 1 to 80 percent of the weight of the bactericidal composition, the thiophanate methyl or carbendazim serving as the active component B accounts for 1 to 80 percent of the weight of the bactericidal composition, and an assistant and an excipient account for the balance of the weight of the bactericidal composition. The carbendazim and thiophanate methyl composite, prepared in the invention, can be formed into wettable powder, water dispersible granules and suspension for preventing and controlling alternaria leaf spot in apple trees, sigatoka, grape powdery mildew, vegetables powdery mildew, venturia pirina, rice blast, anthracnose and the like with obvious synergic effect.
Description
Technical field
The invention belongs to technical field of pesticide, be specifically related to the composite bactericidal composition of a kind of metconazole and carbendazim, probenazole or thiophanate-methyl, be used to prevent and treat the various crop disease.
Technical background
Metconazole (Metconazole) is the trendy triazole bactericidal agent of Japanese Wu Yu chemical company in the early 1990s exploitation, molecular formula: C
17H
22ClN
3O, structural formula:
Metconazole is a C-14 demethylation enzyme inhibitor in the ergosterol biosynthesis.Though the mechanism of action is the same with other triazole bactericidal agents, activity profile then difference is bigger.Two kinds of isomer all have bactericidal activity, but that the cis activity is higher than is trans.The antifungal spectrum of metconazole is very extensive, and active splendid.The metconazole field is used and cereal septoria musiva, fusarium and handle rest fungus is planted disease remarkable effect is arranged.Metconazole is compared with traditional biocide agent, and dosage is extremely low and prevent and treat cereal to plant the disease scope very wide.
Long-term practical application shows that the agent of metconazole list is used for a long time, and disease is developed immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.
Summary of the invention
Metconazole of the present invention and carbendazim, probenazole or thiophanate-methyl complex preparation can be used for preventing and treating the multiple diseases on the crop, and crop is had excellent protection and therapeutic action, and field trial has showed extremely strong antibiotic and bactericidal activity.
The present invention realizes in the following manner:
A kind of bactericidal composition that contains metconazole, comprise effective active component, auxiliary agent and filler, it is characterized in that: two kinds of active component ratios of weight and number of A, B are 1～80: 80～1, and described A is selected from metconazole, and B is selected from a kind of in thiophanate-methyl, carbendazim, the probenazole.
Described a kind of bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 1～60: 60～1.
Described a kind of bactericidal composition that contains metconazole, it is characterized in that: the ratio of weight and number of metconazole and thiophanate-methyl is preferably 2～40: 5～60, be preferably 2～30: 10～50.
Described a kind of bactericidal composition that contains metconazole, it is characterized in that: the ratio of weight and number of metconazole and carbendazim is 2～40: 5～60, is preferably 2～30: 10～50.
Described a kind of bactericidal composition that contains metconazole, it is characterized in that: the ratio of weight and number of metconazole and probenazole is 2～40: 5～60, is preferably 2～30: 10～50.
Described a kind of bactericidal composition that contains metconazole, it is characterized in that: wherein the effective active component content accounts for 1～95% of gross weight.
Described a kind of bactericidal composition that contains metconazole, it is characterized in that: wherein the effective active component content accounts for 10～80% of gross weight.
The described bactericidal composition that contains metconazole by technology known in those skilled in the art, adds auxiliary agent and excipients and can be made into any formulation that allows on the agricultural chemicals, more preferably has: wetting powder, water dispersible granules, suspending agent, suspension emulsion.
The described metconazole bactericidal composition that contains is characterized in that auxiliary agent and excipients comprise: dispersant, wetting agent, disintegrant, thickener, emulsifier, antifreeze, defoamer, filler.
When making wetting powder, composition comprises following constituent content: metconazole 1～80%, active ingredient B1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%.
Metconazole, active ingredient B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into wetting powder product of the present invention.
When making water dispersible granules, composition comprises following constituent content: metconazole 1～80%, active ingredient B1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～90%.
Metconazole, active ingredient B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes water dispersible granules product of the present invention.
Comprise following constituent content when composition is made suspending agent: metconazole 1～40%, active ingredient B 1～50%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active components A, active ingredient B, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes suspending agent product of the present invention.
Comprise following constituent content when composition is made suspension emulsion: metconazole 1～40%, active component B 1～50%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned formulation material are mixed through high speed shear, add active ingredient B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make active ingredient B suspending agent, then with metconazole, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.
Described dispersant is selected from one or more in polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, the fatty acid glyceride APEO.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, DBSA, Nekal BX, wetting and penetrating agent F, alkylnaphthalene sulfonate, polyoxyethylene triphenylethylene phosphenylic acid salt, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, the sodium bicarbonate.
Described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol.
Described emulsifier is selected from one or more among alkyl benzene sulfonate calcium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 506#, 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80, the 602#;
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, the glycerine.
Described defoamer is selected from: one or more in silicone oil, silicone compound, C10-20 saturated fat acid compounds, the C8-10 aliphatic alcohols compound.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
It is remarkable that the described bactericidal composition that contains metconazole is used to prevent and treat effects such as sigatoka, alternaria leaf spot of apple, ring spot, grape powdery mildew, vegetables powdery mildew, anthracnose, pear scab, wheat powdery mildew, rust, rice blast, banded sclerotial blight, compare with single agent, have obvious synergistic effect.
The present invention has following characteristics:
1. double action mechanism, germ are difficult for producing resistance;
2. synergistic effect is obvious.Indoor biometrics is tested the result and shown: metconazole and carbendazim, probenazole or thiophanate-methyl are composite by a certain percentage to have clearly synergistic effect to crop pest;
3. expansion fungicidal spectrum.Metconazole and carbendazim, probenazole or thiophanate-methyl be composite prevent and treat fruit tree and vegetable and and cereal on multiple main disease, as ring rot of apple, alternaria leaf spot of apple, powdery mildew, brown spot, anthracnose, citrus anthracnose, penicilliosis, green mould, wheat powdery mildew, rust, glume blight, rice sheath blight disease, rice blast, false smut etc., enlarged fungicidal spectrum.
4. reduction use cost.The independent use cost of metconazole is higher, is mixed with lower-cost carbendazim, probenazole, thiophanate-methyl and can reduces use cost, enlarges its scope of application.
5. genus environment friendly agricultural.Metconazole, carbendazim, probenazole, thiophanate-methyl all belong to low-toxin farm chemicals, its complex preparation, and high-efficiency low-toxicity to crop and Environmental security, helps the sustainable development of agricultural production.
Embodiment
The present invention will be further described for following examples, but the present invention is not limited thereto.
Embodiments of the invention are the methods that adopt indoor bioassay and field trial to combine.By indoor bioassay, the co-toxicity coefficient after clear and definite two kinds of medicaments are composite by a certain percentage on this basis, carries out field trial more earlier.
Implementation of an application example one metconazole and carbendazim, probenazole or thiophanate-methyl different proportion are used the Toxicity Determination to apple mildew with
1, experimental condition
Apple mildew: the apple mildew bacterial classification that indoor 4 ℃ of refrigerators are preserved is transferred on the PDA medium, in 28 ℃ of incubators, cultivate and make its activation, through standby after twice switching.
2, test medicine
The former medicine of metconazole, content 96% (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
Carbendazim active compound, content 98% (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
The former medicine of probenazole, content 98% (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
The former medicine of thiophanate-methyl, content 89% (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
3, experiment is handled
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.
4, test method
Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ".This experiment adopts the mycelial growth rate method to measure the virulence of medicament to the apple mildew bacterium.Concrete grammar is as follows: the apple mildew bacteria strain through the switching spark is cultivated with PDA, when treating that bacterium colony grows to culture dish 3/4ths size, is that the card punch of 5mm punches from the edge with internal diameter, and the mycelia piece that breaks into is as inoculum.The soup 4ml that respectively handles that gets the concentration for preparing respectively and be 10 times of above-mentioned design concentrations evenly mixes with quantitative 36ml sterilization PDA medium, divide and pour in 3 sterilization culture dishes, make the pastille flat board after the cooling, be mixed into contrast, 4 repetitions of every Treatment Design with equivalent aqua sterilisa and culture dish.To inoculate mycelia and be inverted in dull and stereotyped central authorities, and put into 28 ℃ of incubators and cultivate.Measure colony diameter with the right-angled intersection method behind the 96h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
5, calculate
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively metconazole and carbendazim, probenazole, thiophanate-methyl shared ratio in combination.
A is a metconazole
B is carbendazim, probenazole or thiophanate-methyl
6, experimental result and analysis
Table 1 metconazole, carbendazim and use toxicity test analysis of results table with to rice sheath blight disease
As shown in Table 1, metconazole, carbendazim are to the EC of rice sheath blight disease germ
50Be respectively 1.03 μ g/mL and 17.36 μ g/mL.The virulence of metconazole is apparently higher than the virulence of carbendazim.1: 80 to 40: 1 synergy ratio of metconazole and carbendazim proportioning shows as synergistic effect all greater than 1.5, especially when metconazole and carbendazim proportioning at 1: 20 between 1: 1 the time, synergistic effect is the most obvious.
Table 2 metconazole, thiophanate-methyl and use toxicity test analysis of results table with to apple mildew
As shown in Table 2, metconazole, carbendazim are to the EC of apple mildew germ
50Be respectively 1.06 μ g/mL and 18.45 μ g/mL.The virulence of metconazole is apparently higher than the virulence of thiophanate-methyl.1: 80 to 40: 1 synergy ratio of metconazole and carbendazim proportioning shows as synergistic effect entirely greater than 1.5, especially when metconazole and carbendazim proportioning at 1: 20 between 1: 1 the time, synergistic effect is the most obvious.
Table 3 metconazole, probenazole and use toxicity test analysis of results table with to the banana crown rot
As shown in Table 3, metconazole, carbendazim are to the EC of banana crown rot germ
50Be respectively 1.11 μ g/mL and 7.35 μ g/mL.The virulence of metconazole is apparently higher than the virulence of thiophanate-methyl.1: 80 to 40: 1 synergy ratio of metconazole and carbendazim proportioning shows as synergistic effect entirely greater than 1.5, especially when metconazole and carbendazim proportioning at 1: 20 between 5: 1 the time, synergistic effect is the most obvious.
Implementation of an application example two metconazoles and carbendazim, probenazole or thiophanate-methyl compounded formula material and field control effectiveness test
Embodiment 1:50% metconazole carbendazol wettable powder
Get the former medicine 5g of metconazole, carbendazim active compound 45g, carboxymethyl cellulose 5g, di-2-ethylhexylphosphine oxide benzene sulfonic acid sodium salt 3g, neopelex 5g, white carbon black 10g, kaolin 27g places agitator to stir, and promptly can be made into 50% metconazole carbendazol wettable powder through comminution by gas stream to 500 orders.
Embodiment 2:50% metconazole thiophanate-methyl wetting powder
Get the former medicine 5g of metconazole, the former medicine 45g of thiophanate-methyl, polycarboxylate 5g, neopelex 4g, white carbon 10g, diatomite 28g places agitator to stir, and promptly can be made into 50% metconazole thiophanate-methyl wetting powder through comminution by gas stream to 500 orders.
Embodiment 3:50% metconazole probenazole wetting powder
Get the former medicine 10g of metconazole, the former medicine 40g of probenazole, polycarboxylate 4g, rice mahogany sulfonate 5g, white carbon 10g, kaolin 28g places agitator to stir, and promptly can be made into 50% metconazole probenazole wetting powder through comminution by gas stream to 500 orders.
50% metconazole carbendazim WP, 50% metconazole thiophanate-methyl WP, 50% metconazole probenazole WP prevent and treat the ring rot of apple field trial
1, test medicine
50% metconazole carbendazim WP (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
50% metconazole probenazole WP (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
50% metconazole thiophanate-methyl WP (Shaanxi agricultural chemicals Co., Ltd of U.S. nation provides)
2, contrast medicament
60g/L metconazole aqueous emulsion EW
50% carbendazol wettable powder WP
70% thiophanate-methyl wetting powder WP
45% probenazole suspending agent SC
3, dosing and processing numbering
Table 3 reagent agent experimental scheme
4, spraying time and number of times
Totally three dispensers, May 8 is dispenser for the first time when disease just takes place, and carries out the second time and dispenser for the third time respectively on May 18 and May 28.
5, control time and method
Radix investigation (May 8) before the dispenser, carry out respectively on May 18, May 28, June 8 for the first time, for the second time, dispenser " Invest, Then Investigate " for the third time.
According to apple tree leaf sheath and blade hazard symptoms grading, be unit with the strain, diagonal 5 samplings in every sub-district are investigated adjacent 5 clumps, totally 25 clumps, are write down total strain number, diseased plant number and sick progression for every.
Stage division:
0 grade: complete stool is anosis;
1 grade: quaterfoil and following each leaf sheath thereof, blade morbidity (is first leaf with sword-like leave);
3 grades: the 3rd blade and following each leaf sheath thereof, blade morbidity;
5 grades: second blade and following each leaf sheath thereof, blade morbidity;
7 grades: sword-like leave blade and following each leaf sheath, blade morbidity;
9 grades: full leaf morbidity, fall leaves.
6, drug effect computational methods
In the formula: CK
0Disease index before the dispenser of-blank district;
CK
1Disease index after the dispenser of-blank district;
PT
0Disease index before the dispenser of-chemicals treatment district;
PT
1Disease index after the dispenser of-chemicals treatment district.
7, test results and analysis
The composite ring rot of apple result of the test of preventing and treating of table 4 metconazole and carbendazim, probenazole or thiophanate-methyl
As shown in Table 4, metconazole and carbendazim, probenazole or thiophanate-methyl are composite remarkable to the ring rot of apple control efficiency, compare with single agent, have preventive effect height, long, residual little advantage of lasting period, in the test scope of medication, the target crop are had no adverse effects.
Embodiment 4:80% metconazole carbendazim water dispersing granule
Get the former medicine 8g of metconazole, carbendazim active compound 72g, sodium lignin sulfonate 5g, lauryl sodium sulfate 8g, ammonium sulfate 4g, starch 3g, formulation material is mixed, pulverize, through mediating with micro jet, add then and carry out granulation, drying, screening in the fluidized bed prilling dryer after sample analysis can be made into 80% metconazole carbendazim water dispersing granule.
Embodiment 5:80% metconazole thiophanate-methyl water dispersible granules
Get the former medicine 10g of metconazole, the former medicine 70g of thiophanate-methyl, alkyl benzene sulfonate calcium salt 5g, wetting and penetrating agent F 3g, neopelex 5g, starch 2g, kaolin 5g mixes formulation material, pulverize with micro jet, through mediating, add then and carry out granulation, drying, screening in the fluidized bed prilling dryer after sample analysis can be made into 80% metconazole thiophanate-methyl water dispersible granules.
Embodiment 6:80% metconazole probenazole water dispersible granules
Get the former medicine 20g of metconazole, the former medicine 60g of probenazole, alkyl benzene sulfonate calcium salt 5g, soapberry powder 3g, neopelex 5g, starch 2g, kaolin 5g mixes formulation material, pulverize with micro jet, through mediating, add then and carry out granulation, drying, screening in the fluidized bed prilling dryer after sample analysis can be made into 80% metconazole probenazole water dispersible granules.
Composite ring rot of apple test of pesticide effectiveness result such as the table 5 prevented and treated of metconazole and carbendazim, probenazole or thiophanate-methyl:
The composite ring rot of apple result of the test of preventing and treating of table 5 metconazole and carbendazim, probenazole or thiophanate-methyl
As shown in Table 5, metconazole and carbendazim, probenazole or thiophanate-methyl are composite remarkable to the alternaria leaf spot of apple control efficiency, compare with single agent, have preventive effect height, long, residual little advantage of lasting period.In this experimental drug weight range, to apple safety, have no adverse effects, preparation of the present invention also has good control efficiency to apple anthracnose, apple marssonina leaf spot.
Embodiment 7:20% metconazole probenazole suspending agent
Get the former medicine 5g of metconazole, the former medicine 15g of probenazole, neopelex 5g, ethylene glycol 3g, aluminium-magnesium silicate 0.8g, xanthans 0.1g, silicone defoaming agent 0.1g, white carbon 1g, water surplus.With in the above-mentioned formulation material except that crossing all the other components of active ingredient, mix through high speed shear, adding active ingredient, ball milling is 2～3 hours in ball mill, makes particle diameter all below 5 μ m, makes 20% metconazole probenazole suspending agent.
Embodiment 8:42% metconazole thiophanate-methyl suspending agent
Get the former medicine 6g of metconazole, the former medicine 36g of thiophanate-methyl, alkyl benzene calcium sulfonate 5g, glycerine 3g, aluminium-magnesium silicate 0.8g, xanthans 0.1g, silicone defoaming agent 0.1g, white carbon 1g, water surplus.Back in the above-mentioned formulation material except that crossing all the other components of active ingredient, is mixed through high speed shear, adding active ingredient, ball milling is 2～3 hours in ball mill, makes particle diameter all below 5 μ m, makes 30% metconazole thiophanate-methyl suspending agent.
Embodiment 9:45% metconazole carbendazim suspending agent
Get the former medicine 5g of metconazole, carbendazim active compound 40g, neopelex 5g, second triol 3g, aluminium-magnesium silicate 0.8g, xanthans 0.1g, silicone defoaming agent 0.1g, white carbon 1g, water surplus.With in the above-mentioned formulation material except that crossing all the other components of active ingredient, mix through high speed shear, adding active ingredient, ball milling is 2～3 hours in ball mill, makes particle diameter all below 5 μ m, makes 45% metconazole carbendazim suspending agent.
The composite control pepper anthracnose of metconazole and carbendazim, probenazole or thiophanate-methyl test of pesticide effectiveness result such as table 6:
The composite control pepper anthracnose of table 6 metconazole and carbendazim, probenazole or thiophanate-methyl result of the test
As shown in Table 6, metconazole and carbendazim, probenazole or thiophanate-methyl are composite remarkable to the pepper anthracnose control efficiency, compare with single agent, have preventive effect height, long, residual little advantage of lasting period.In this experimental drug weight range,, have no adverse effects to oranges and tangerines safety.
Embodiment 10:
Table 7 metconazole and carbendazol wettable powder control grape powdery mildew result of the test
| Content | 80％ | 60％ | 70％ | 40％ |
| Metconazole | 5g | 40g | 70g | 10g |
| Carbendazim | 75g | 20g | 10g | 30g |
| Dispersant | Neopelex 5g | Sodium carboxymethylcellulose 8g | Dispersant 6g | Lignosulfonates 8g |
| Wetting agent | The withered powder 1g of tea | Spaonin powder 3g | Draw back powder 3g | Wetting agent F5g |
| Filler | Kaolin 24g | White carbon 29g | White carbon 21g | Precipitated calcium carbonate 47g |
| Extension rate | 1500 times | 2500 times | 3500 times | 1000 times |
| Control efficiency | 90.49％ | 88.87％ | 98.96％ | 89.56％ |
Table 8 metconazole and thiophanate-methyl wetting powder are prevented and treated the sigatoka result of the test
Table 9 metconazole and probenazole wetting powder control oranges and tangerines penicilliosis result of the test
Embodiment 11:
Table 10 metconazole and probenazole water dispersible granules control vegetables downy mildew result of the test
| Content | 70％ | 62％ | 50％ | 78％ |
| Metconazole | 40g | 12g | 35g | 68g |
| Probenazole | 30g | 50g | 15g | 10g |
| Dispersant | Sodium lignin sulfonate 6g | Two sodium naphthasulfonate 5g | Carboxymethyl cellulose 6g | Sodium lignin sulfonate 7g |
| Wetting agent | Bleeding agent F3g | Spaonin powder 5g | Silkworm excrement 4g | Draw back powder 3g |
| Thickener | Starch 3g | Gum Arabic 1g | Polyvinyl alcohol 2g | Starch 2g |
| Disintegrant | Citric acid 2g | Tartaric acid 3g | Succinic acid 3g | Metconazole diacid 4g |
| Filler | Kaolin 16g | Bentonite 24g | Diatomite 35g | Starch 6g |
| Extension rate | 2500 times | 2000 times | 2000 times | 3000 times |
| Control efficiency | 87.50％ | 88.46％ | 91.09％ | 97.52％ |
Table 11 metconazole and thiophanate-methyl water dispersible granules control pear scab result of the test
| Content | 84％ | 78％ | 55％ | 45％ |
| Metconazole | 5g | 20g | 13g | 40g |
| Thiophanate-methyl | 79g | 58g | 42g | 5g |
| Dispersant | Polycarboxylate 3g | Aliphatic amine polyoxyethylene ether 5g | Carboxymethyl cellulose 6g | Dispersant NNO7g |
| Wetting agent | Silkworm excrement 1g | Lauryl sodium sulfate 5g | Wetting and penetrating agent T3g | Draw back powder 3g |
| Thickener | Starch 3g | Polyethylene glycol 1g | Polyvinyl alcohol 2g | Starch 2g |
| Disintegrant | Ammonium sulfate 2g | Carbonic hydroammonium 3g | Succinic acid 3g | Metconazole diacid 3g |
| Filler | Kaolin 7g | Bentonite 8g | Diatomite 31g | Kaolin 40g |
| Extension rate | 1100 times | 2000 times | 1000 times | 2500 times |
| Control efficiency | 87.50％ | 90.58％ | 92.47％ | 89.55％ |
Table 12 metconazole and carbendazim water dispersing granule control vegetables powdery mildew result of the test
| Content | 70％ | 62％ | 50％ | 78％ |
| Metconazole | 60g | 12g | 15g | 18g |
| Carbendazim | 10g | 50g | 35g | 70g |
| Dispersant | Sodium lignin sulfonate 6g | Two sodium naphthasulfonate 5g | Carboxymethyl cellulose 6g | Sodium lignin sulfonate 7g |
| Wetting agent | Bleeding agent F3g | Spaonin powder 5g | Silkworm excrement 4g | Draw back powder 3g |
| Thickener | Starch 3g | Gelatin 1g | Polyvinyl alcohol 2g | Starch 2g |
| Disintegrant | Citric acid 2g | Tartaric acid 3g | Sodium chloride 3g | Metconazole diacid 4g |
| Filler | Kaolin 16g | Bentonite 24g | Diatomite 35g | Starch 6g |
| Extension rate | 2500 times | 1500 times | 2000 times | 3200 times |
| Control efficiency | 88.50％ | 88.46％ | 91.09％ | 97.52％ |
Embodiment 12:
Table 13 metconazole and carbendazim suspension emulsion control rice blast result of the test
Table 14 metconazole and carbendazim suspension emulsion are prevented and treated the rice sheath blight disease result of the test
Table 15 metconazole and thiophanate-methyl suspension emulsion control wheat powdery mildew result of the test
By above-mentioned experimental results show that; after metconazole and carbendazim, probenazole or thiophanate-methyl are composite; prevent and treat sigatoka, apple tree spot defoliation, ring spot, powdery mildew, vegetables powdery mildew, pear scab, rice blast, banded sclerotial blight, anthracnose etc. good synergistic effect is all arranged; and enlarged fungicidal spectrum; one medicine is controlled more; saved medication and recruitment cost, good to environmental protection property.
Claims (7)
1. bactericidal composition that contains metconazole, comprise effective active component, auxiliary agent and filler, it is characterized in that: two kinds of active component ratios of weight and number of A, B are 1～80: 80～1, and described A is selected from metconazole, and B is selected from a kind of in thiophanate-methyl, carbendazim, the probenazole.
2. a kind of bactericidal composition that contains metconazole according to claim 1 is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 1～60: 60～1.
3. a kind of bactericidal composition that contains metconazole according to claim 2 is characterized in that: the ratio of weight and number of metconazole and thiophanate-methyl is 2～40: 5～60.
4. a kind of bactericidal composition that contains metconazole according to claim 2 is characterized in that: the ratio of weight and number of metconazole and carbendazim is 2～40: 5～60.
5. a kind of bactericidal composition that contains metconazole according to claim 2 is characterized in that: the ratio of weight and number of metconazole and probenazole is 2～40: 5～60.
6. a kind of bactericidal composition that contains metconazole according to claim 1, it is characterized in that: wherein the effective active component content accounts for 1～95% of gross weight.
7. a kind of bactericidal composition that contains metconazole according to claim 6, it is characterized in that: wherein the effective active component content accounts for 10～80% of gross weight.
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| CN201010607226XA CN102017971A (en) | 2010-12-27 | 2010-12-27 | Metconazole-containing bactericidal composition |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103168786A (en) * | 2013-03-15 | 2013-06-26 | 江苏七洲绿色化工股份有限公司 | Ternary compound bactericidal composition and application thereof |
| CN103444742A (en) * | 2013-09-24 | 2013-12-18 | 南京农业大学 | Sterilization composition containing metconazole and albendazole |
| CN104186489A (en) * | 2014-09-22 | 2014-12-10 | 江苏丘陵地区镇江农业科学研究所 | Sterilizing composition containing metconazole and picoxystrobin |
| CN104686540A (en) * | 2015-03-31 | 2015-06-10 | 河南科技学院 | Sterilization compound with metconazole and fenpyrazamine and purposes of sterilization compound |
| CN114885949A (en) * | 2022-06-02 | 2022-08-12 | 农心作物科技股份有限公司 | Application of composition containing metconazole to prevention and treatment of wheat stem basal rot |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001302420A (en) * | 2000-04-28 | 2001-10-31 | Nippon Soda Co Ltd | Fungicide composition for agriculture and horticulture |
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2010
- 2010-12-27 CN CN201010607226XA patent/CN102017971A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001302420A (en) * | 2000-04-28 | 2001-10-31 | Nippon Soda Co Ltd | Fungicide composition for agriculture and horticulture |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103168786A (en) * | 2013-03-15 | 2013-06-26 | 江苏七洲绿色化工股份有限公司 | Ternary compound bactericidal composition and application thereof |
| CN103168786B (en) * | 2013-03-15 | 2014-09-10 | 江苏七洲绿色化工股份有限公司 | Ternary compound bactericidal composition and application thereof |
| CN103444742A (en) * | 2013-09-24 | 2013-12-18 | 南京农业大学 | Sterilization composition containing metconazole and albendazole |
| CN104186489A (en) * | 2014-09-22 | 2014-12-10 | 江苏丘陵地区镇江农业科学研究所 | Sterilizing composition containing metconazole and picoxystrobin |
| CN104686540A (en) * | 2015-03-31 | 2015-06-10 | 河南科技学院 | Sterilization compound with metconazole and fenpyrazamine and purposes of sterilization compound |
| CN114885949A (en) * | 2022-06-02 | 2022-08-12 | 农心作物科技股份有限公司 | Application of composition containing metconazole to prevention and treatment of wheat stem basal rot |
| CN114885949B (en) * | 2022-06-02 | 2023-11-03 | 农心作物科技股份有限公司 | Application of metconazole-containing composition in preventing and treating wheat stem basal rot |
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