Summary of the invention
The objective of the invention is to propose a kind of generation or delaying drug resistance speed that can prevent disease drug resistance, the bactericidal composition that contains fludioxonil that use cost is low, preventive effect is good.
The inventor is by a large amount of indoor biometricses and field control effectiveness test, a kind of use that is mixed within the specific limits in unexpected discovery fludioxonil and propiconazole, carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, fludioxonil, the polyoxin has good synergistic effect to diseases such as powdery mildew, bakanae disease, rice blast, banded sclerotial blight, damping off, gray mold, root rot.
The bactericidal composition that the present invention proposes contains two kinds of active components of A, B.
Active component A is selected from a kind of in propiconazole, carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, fludioxonil, the polyoxin.
Described carbendazim (carbendazim) belongs to benzimidazole, and molecular formula is C
9H
9N
3O
2, chemical name: N-(2-benzimidazolyl) methyl carbamate.The carbendazim high-efficiency low-toxicity, effective to sac fungi and imperfect fungus, invalid to oomycetes and bacterial disease, have protection and therapeutic action.The mechanism of action is the formation of imitative hammer body in the mitosis of disturbing bacterium, thereby influences cell division.
Described cyprodinil (cyprodinil), molecular formula: C
14H
15N
3, chemical name: 4-cyclopropyl-6-methyl-N-phenyl pyrimidine-2-amine.Fludioxonil belongs to the miazines bactericide.By suppressing the biosynthesis of methionine moral, suppress the secretion of hydrolase.Absorbed rapidly by blade in plant corpus, be penetrated into more than 30% in the tissue, protected sediment is stored in the blade; transmit in xylem, also transmit between blade, metabolism at high temperature is rapid relatively; sediment quite stable under the low temperature in blade, metabolite inanimate object activity.
Described propiconazole (propiconazol), molecular formula: C
15H
17O
2N
3Cl
2, chemical name: 1-[2-(2,4 dichloro benzene base)-4-propyl group-1; 3-dioxolanes-Alpha-Methyl]-1-hydrogen-1,2, the 4-triazole; propiconazole is a kind of systemic fungicide with protection and therapeutic action; can be absorbed by root, stem, leaf portion, and can be soon in the plant body on conduction, propiconazole can be prevented and treated sac fungi; the caused disease of basidiomycetes and imperfect fungus; particularly to root rotof flax, powdery mildew, bakanae disease of rice have the better prevention effect.
Described tmtd (thiram), molecular formula are C
6H
12N
2S
4, chemical name: tetramethyl thiuram disulfide.Tmtd is a kind of bactericide of tool protective effect, and its has a broad antifungal spectrum is mainly used in and handles seed and soil, the seedling blight of control cereal class smut and various crop.Also can be used for spraying, prevent and treat some fruit trees, vegetable disease.
Described 2-cyano-3-amino-3-phenylancryic acetate, molecular formula are C
12H
12N
2O
2, chemical name: 2-cyano group-3-amino-3-aminoacrylic acid ethyl ester.2-cyano-3-amino-3-phenylancryic acetate is effective to the disease that the reaping hook mushroom causes, has protective effect and therapeutic action.Be absorbed by root, upwards transporting arranged on blade, towards the blade bottom and interlobate transporting relatively poor.
Described polyoxin (polyoxin), molecular formula are C
17H
25N
5O
14, chemical name: peptide pyrimidine nucleoside.The broad-spectrum antibiotics class, inhale conduction in having preferably, its mechanism of action is to disturb the chitinous biosynthesis of bacterial cell wall, and germ tube is with after mycelium contacts medicament, expand the part, break, overflow cell inclusion, and can not normal development, cause death, suppress germ in addition and produce spore and scab expansion effect, this medicine does not have toxicity to animal, and plant is not had poisoning.Main controlling object has wheat powdery mildew, Alternaria alternate, cucumber downy mildew, cucurbits fusarium wilt, genseng black spot, rice sheath blight disease, alternaria leaf spot of apple, strawberry and grape grey mould, multiple fungal diseases such as forest spike top and pears black spot.
Active component B is a fludioxonil.
The ratio of weight and number of A, two kinds of active components of B is 50: 1~1: 50, and preferred ratio of weight and number is 20: 1~1: 20.
The described bactericidal composition that contains fludioxonil is characterized in that: the ratio of weight and number of active component cyprodinil and fludioxonil is 20: 1~1: 5, and further preferred ratio of weight and number is 10: 1~1: 1.
The described bactericidal composition that contains fludioxonil is characterized in that: the ratio of weight and number of active component 2-cyano-3-amino-3-phenylancryic acetate and fludioxonil is 20: 1~1: 5, and further preferred ratio of weight and number is 10: 1~1: 1.
The described bactericidal composition that contains fludioxonil is characterized in that: the ratio of weight and number of active component tmtd and fludioxonil is 20: 1~1: 1, and further preferred ratio of weight and number is 10: 1~1: 1.
The described bactericidal composition that contains fludioxonil is characterized in that: the ratio of weight and number of active component carbendazim and fludioxonil is 20: 1~1: 1, and further preferred ratio of weight and number is 10: 1~1: 1.
The described bactericidal composition that contains fludioxonil is characterized in that: the ratio of weight and number of active component propiconazole and fludioxonil is 10: 1~1: 10, and further preferred ratio of weight and number is 5: 1~1: 5.
The described bactericidal composition that contains fludioxonil is characterized in that: the ratio of weight and number of active component polyoxin and fludioxonil is 10: 1~1: 10, and further preferred ratio of weight and number is 5: 1~1: 5.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 1~90% of a gross weight in the composition, and preferable is 10%~80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1~70% active substance by weight, preferably is 5~50%; Solid pharmaceutical preparation contains 5~85% active substance by weight, preferably is 10~80%.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand, and the wherein excellent formulation of selecting is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5~30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, emulsifier or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by common processing method preparation known in those skilled in the art, be about to active substance and after liquid flux or solid carrier mix, add in surfactant such as dispersant, stabilizing agent, wetting agent, binding agent, the defoamer etc. one or more again.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, the aluminium chloride.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8~10Aliphatic alcohols, C
10~20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from one or more among alkyl benzene sulfonate calcium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 506#, 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80, the 602#;
Described co-emulsifier is one or more in butanols, isobutanol, dodecanol-1, tetradecanol-1, the octadecanol-1;
Described solvent is selected from one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, vegetable oil, dimethyl formamide, acetonitrile, polyethylene glycol, pyrrolidones, the solvent N-chain alkyl pyrrolidones;
Described preservative is selected from one or more in formaldehyde, sodium salicylate, Sodium Benzoate, the dichlorophen;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Microbicide compositions of the present invention has protection concurrently, treats and roots out activity, for example can be used for various crop: wheat, paddy rice, vegetables, fruit tree etc., the microbial plant disease of cause of disease of control capsule bacterium subphylum, Basidiomycotina and Deuteromycotina.Powdery mildew, bakanae disease, rice blast, banded sclerotial blight, damping off, gray mold, root rot there is special efficacy.
Therefore, composition of the present invention has following advantage: (one) said composition shows significant synergistic effect in certain ratio range, both improved protection effect, has reduced mu dosage and cost, has enlarged fungicidal spectrum again; (2) since in the said composition each active component do not have the problem of cross resistance, so the application of said composition can reach and delay drug-fast generation of pathogen and development, the result of use that helps to prolong this medicament reduces pesticide resistance and produces probability; (3) improved safety, being mixed will be lower to the influence of environment, safer.
Embodiment
To further instruction of the present invention, the percentage among the embodiment is ratio of weight and number below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one: Toxicity Determination
Active components A (A be selected from propiconazole, cyprodinil, 2-cyano-3-amino-3-phenylancryic acetate, tmtd, carbendazim, the polyoxin a kind of) is composite to crop germ Toxicity Determination with fludioxonil
Target: graw mold of tomato; Armillariella root rot of apple; Rice sheath blight disease; Bakanae disease of rice; Cucumber downy mildew; Powdery mildew of cucumber.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament target.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR<0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A (propiconazole, carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, polyoxin) and fludioxonil shared ratio in combination;
A is a kind of in propiconazole, carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, the polyoxin;
B is a fludioxonil.
Result of the test is as shown in the table:
Toxicity test result one
Carbendazim, fludioxonil and composite toxicity test thereof to powdery mildew of cucumber
Table 1 carbendazim, fludioxonil and composite toxicity test analysis of results table thereof to powdery mildew of cucumber
As shown in Table 1, carbendazim, fludioxonil are to the EC of powdery mildew of cucumber
50Be respectively 18.67mg/L and 1.56mg/L.Carbendazim and fludioxonil were mixed in the scope at 50: 1~1: 50 and all show obvious synergistic effect.Wherein, carbendazim and fludioxonil mixed synergies in 20: 1~1: 20 scope is comparatively desirable, and mixed synergies is particularly outstanding in 20: 1~1: 1 scope.
Toxicity test result two
Propiconazole, fludioxonil and composite toxicity test thereof to rice sheath blight disease
Table 2 propiconazole, fludioxonil and composite toxicity test analysis of results table thereof to rice sheath blight disease
As shown in Table 2, propiconazole, fludioxonil are to the EC of rice sheath blight disease
50Be respectively 3.38mg/L and 1.75mg/L.Propiconazole and fludioxonil were mixed in the scope at 50: 1~1: 50 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1~1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1~1: 10 scope.
Toxicity test result three
Cyprodinil, fludioxonil and composite toxicity test thereof to graw mold of tomato
Table 3 cyprodinil, fludioxonil and composite toxicity test analysis of results table thereof to graw mold of tomato
As shown in Table 3, cyprodinil, fludioxonil are to the EC of graw mold of tomato
50Be respectively 10.62mg/L and 1.23mg/L.Cyprodinil and fludioxonil were mixed in the scope at 50: 1~1: 50 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1~1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 20: 1~1: 5 scope.
Toxicity test result four
2-cyano-3-amino-3-phenylancryic acetate, fludioxonil and composite toxicity test thereof to armillariella root rot of apple
Table 4 2-cyano-3-amino-3-phenylancryic acetate, fludioxonil and composite toxicity test analysis of results table thereof to armillariella root rot of apple
As shown in Table 4,2-cyano-3-amino-3-phenylancryic acetate, fludioxonil are to the EC of armillariella root rot of apple
50Be respectively 6.16mg/L and 1.21mg/L.2-cyano-3-amino-3-phenylancryic acetate and fludioxonil were mixed in the scope at 50: 1~1: 50 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1~1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 20: 1~1: 5 scope.
Toxicity test result five
Tmtd, fludioxonil and composite toxicity test thereof to bakanae disease of rice
Table 5 tmtd, fludioxonil and composite toxicity test analysis of results table thereof to bakanae disease of rice
As shown in Table 5, tmtd, fludioxonil are to the EC of bakanae disease of rice
50Be respectively 15.63mg/L and 1.38mg/L.Tmtd and fludioxonil were mixed in the scope at 50: 1~1: 50 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1~1: 10 scope are comparatively desirable, and mixed synergies is particularly outstanding in 20: 1~1: 1 scope.
Toxicity test result six
Polyoxin, fludioxonil and composite toxicity test thereof to cucumber downy mildew
Table 6 polyoxin, fludioxonil and composite toxicity test analysis of results table thereof to cucumber downy mildew
As shown in Table 6, polyoxin, fludioxonil are to the EC of cucumber downy mildew
50Be respectively 1.18mg/L and 1.34mg/L.Polyoxin and fludioxonil were mixed in the scope at 50: 1~1: 50 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1~1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1~1: 10 scope.
Implementation of an application example two: field control effectiveness test
The embodiment 1 80% carbendazim fludioxonil wetting powder control wheat powdery mildew test of pesticide effectiveness
Carbendazim 70%, fludioxonil 10%, polycarboxylate 3%, lauryl sodium sulfate 3%, silkworm excrement 2%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 80% carbendazim fludioxonil wetting powder.This proportioning is by 30 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control wheat powdery mildew effects are respectively 91.5%, 97.2% behind the medicine, 50% carbendazol wettable powder and 50% fludioxonil wetting powder are according to same quadrat method, use by 100 gram/mus and the dilution of 15 gram/mus respectively, 14 days preventive effects are respectively 64.5% and 68.3% behind the medicine.
In the present embodiment carbendazim replaceable be a kind of in propiconazole, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, the polyoxin, thereby form new embodiment.
Embodiment 2 40% propiconazole fludioxonil aqueous emulsions are prevented and treated the sigatoka test of pesticide effectiveness
Propiconazole 30%, fludioxonil 10%, acetone 8%, n-octyl alcohol 4%, alkylphenol polyoxyethylene phosphate 5%, polyethylene glycol 3%, alkyl benzene calcium sulfonate 5%, sodium chloride 2%, deionized water add to 100%, the mixed 40% propiconazole fludioxonil aqueous emulsion that gets.This proportioning is by 2500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the sigatoka effect in 7 days, 14 days behind the medicine and be respectively 91.8%, 95.6%, 25% propiconazole emulsifiable concentrate and 50% fludioxonil wetting powder are according to same quadrat method, dilute 800 times and 3500 times of uses respectively, 14 days preventive effects are respectively 66.4% and 69.6% behind the medicine.
In the present embodiment propiconazole replaceable be a kind of in carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, the polyoxin, thereby form new embodiment.
Embodiment 3 48% 2-cyano-3-amino-3-phenylancryic acetate fludioxonil suspending agents are prevented and treated the rice sheath blight disease test of pesticide effectiveness
2-cyano-3-amino-3-phenylancryic acetate 40%, fludioxonil 8%, polycarboxylate 3%, lignosulfonates 2%, neopelex 3%, xanthans 0.5%, polyethylene glycol 4%, deionized water add to 100%, the mixed 48% 2-cyano-3-amino-3-phenylancryic acetate fludioxonil suspending agent that gets.This proportioning is by 30 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the rice sheath blight disease effect in 7 days, 14 days behind the medicine and be respectively 91.7%, 96.1%, 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent and 50% fludioxonil wetting powder are according to same quadrat method, use by 120 gram/mus and the dilution of 15 gram/mus respectively, 14 days preventive effects are respectively 70.8% and 71.2% behind the medicine.
In the present embodiment 2-cyano-3-amino-3-phenylancryic acetate replaceable be a kind of in propiconazole, carbendazim, tmtd, cyprodinil, the polyoxin, thereby form new embodiment.
The embodiment 4 30% propiconazole fludioxonil microemulsions control armillariella root rot of apple test of pesticide effectiveness
Propiconazole 10%, fludioxonil 20%, acetone 15%, agricultural newborn 500#8%, butanols 5%, hydroxyethylcellulose 2%, sodium salicylate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, the mixed 30% propiconazole fludioxonil microemulsion that gets.This proportioning is by 2500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control armillariella root rot of apple effects are respectively 91.3%, 95.8% behind the medicine, 25% propiconazole emulsifiable concentrate and 50% fludioxonil wetting powder are according to same quadrat method, dilute 1000 times and 3000 times of uses respectively, 14 days preventive effects are respectively 71.3% and 69.7% behind the medicine.
In the present embodiment propiconazole replaceable be a kind of in carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, the polyoxin, thereby form new embodiment.
The embodiment 5 55% tmtd fludioxonil wetting powders control rice blast test of pesticide effectiveness
Tmtd 50%, fludioxonil 5%, alkyl benzene sulfonate calcium salt 2%, polycarboxylic acids sodium 3%, soapberry powder 2%, kaolin add to 100%, the mixed 55% tmtd fludioxonil wetting powder that gets.This proportioning is by 50 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control rice blast effects are respectively 91.7%, 95.9% behind the medicine, 50% thiram wettable powder and 50% fludioxonil wetting powder are according to same quadrat method, use by 100 gram/mus and 15 gram/mus dilution spraying respectively, 14 days preventive effects are respectively 69.7% and 70.5% behind the medicine.
In the present embodiment tmtd replaceable be a kind of in propiconazole, carbendazim, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, the polyoxin, thereby form new embodiment.
The embodiment 5 70% cyprodinil fludioxonil water dispersible granules control graw mold of tomato test of pesticide effectiveness
Cyprodinil 60%, fludioxonil 10%, sodium lignin sulfonate 3%, polycarboxylic acids sodium 3%, wetting and penetrating agent F 2%, urea 3%, bentonite add to 100%, the mixed 70% cyprodinil fludioxonil water dispersible granules that gets.This proportioning is by 35 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control graw mold of tomato effects are respectively 91.7%, 96.7% behind the medicine, 50% cyprodinil water dispersible granules and 50% fludioxonil wetting powder are according to same quadrat method, use by 75 gram/mus and 18 gram/mus dilution spraying respectively, 14 days preventive effects are respectively 69.7% and 70.5% behind the medicine.
In the present embodiment cyprodinil replaceable be a kind of in propiconazole, carbendazim, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, the polyoxin, thereby form new embodiment.
Embodiment 6 35% 2-cyano-3-amino-3-phenylancryic acetate fludioxonil suspending agents are prevented and treated the bakanae disease of rice test of pesticide effectiveness
2-cyano-3-amino-3-phenylancryic acetate 25%, fludioxonil 10%, polycarboxylate 3%, lignosulfonates 3%, neopelex 2%, silicone oil 0.1%, polyethylene glycol 0.5%, deionized water adds to 100%, the mixed 35% 2-cyano-3-amino-3-phenylancryic acetate fludioxonil suspending agent that gets.This proportioning is by 25 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the bakanae disease of rice drug effect in 7 days, 14 days behind the medicine and really be respectively 91.7%, 96.4%, 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent and 50% fludioxonil wetting powder are according to same quadrat method, use by 120 gram/mus and 15 gram/mus dilution spraying respectively, 14 days preventive effects are respectively 71.5% and 70.8% behind the medicine.
In the present embodiment 2-cyano-3-amino-3-phenylancryic acetate replaceable be a kind of in propiconazole, carbendazim, tmtd, cyprodinil, the polyoxin, thereby form new embodiment.
Embodiment 7 10% carbendazim fludioxonil seed treatments are handled the wheat seed test
Carbendazim 5%, fludioxonil 5%, polycarboxylate 2%, sodium lignin sulfonate 3%, dichlorophen 5%, salicylate hydrochlorate 3%, alkyl benzene sulfonate calcium salt 3%, deionized water adds to 100%, the mixed 10% carbendazim fludioxonil seed treatment that gets.This proportioning is pressed 150g/100kg seed seed dressing, in closed container, seed dressing was mixed 1 minute with the seed jolting, with planting seed to the experimental field, and laggard pedestrian worker's irrigation in one day.After planting 28 days calculate preventive effect is 100%, does not observe and infects.Contrast medicament 50% carbendazim seed dressing and 10% fludioxonil seed dressing calculated preventive effect and are respectively 81.3%, 85.7% by using with quadrat method in after planting 28 days.
In the present embodiment carbendazim replaceable be a kind of in propiconazole, tmtd, 2-cyano-3-amino-3-phenylancryic acetate, cyprodinil, the polyoxin, thereby form new embodiment.
The ratio of A, two kinds of active components of B all can be adjusted in 50: 1~1: 50 synergy scope in the foregoing description, thereby forms new embodiment.