CN102027937A - Bactericidal composition containing metconazole and triazole - Google Patents
Bactericidal composition containing metconazole and triazole Download PDFInfo
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Abstract
The invention discloses a bactericidal composition, which contains synergy effective quantity of metconazole and one of triadimefon, tebuconazole, hexaconazole, cyproconazole, triadimenol, bitertanol and diniconazole serving as a triazole bactericide, wherein the weight part ratio of the two active ingredients in the bactericidal composition is 80:1-1:80. The bactericidal composition at least contains one surfactant which is favorable for dispersion of the active ingredients in water during application. The bactericidal composition has protection, treatment and weeding activities, can be used for multiple crops such as wheat, rice, vegetables, fruit trees and the like, and can be used for preventing and controlling plant diseases caused by pathogenic bacteria of aseomycotina, basidiomycolina and deuteromycotina.
Description
Technical field
The invention belongs to the disinfectant use in agriculture field, relate to a kind of preparation and application that contains the bactericidal composition of metconazole.
Background technology
Metconazole (Metconazole) is the trendy triazole bactericidal agent of Japanese Wu Yu chemical company in the early 1990s exploitation, molecular formula: C
17H
22ClN
3O, structural formula:
Metconazole is a C-14 demethylation enzyme inhibitor in the ergosterol biosynthesis.Though the mechanism of action is the same with other triazole bactericidal agents, activity profile then difference is bigger.Two kinds of isomer all have bactericidal activity, but that the cis activity is higher than is trans.The antifungal spectrum of metconazole is very extensive, and active splendid.The metconazole field is used and cereal septoria musiva, fusarium and handle rest fungus is planted disease remarkable effect is arranged.Metconazole is compared with traditional biocide agent, and dosage is extremely low and prevent and treat cereal to plant the disease scope very wide.
The agent of metconazole list is used for a long time, and disease is developed immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.
Summary of the invention
The objective of the invention is to propose a kind of generation or delaying drug resistance speed that can prevent disease drug resistance, the bactericidal composition that contains metconazole that use cost is low, preventive effect is good.
The inventor is by a large amount of indoor biometricses and field control effectiveness test, unexpected find the use that is mixed within the specific limits of metconazole and triazole bactericidal agent, diseases such as the powdery mildew of cereal crop, rust, rice blast, banded sclerotial blight, leaf spot are had good synergistic effect.Further experiment finds, the use that is mixed within the specific limits of metconazole and triazole bactericidal agent also has good preventive effect to spot defoliation, anthracnose, powdery mildew, the scab of vegetables and fruit tree.And the composite of metconazole and triazole bactericidal agent at home and abroad do not see openly as yet.
The bactericidal composition that the present invention proposes contains two kinds of active components of A, B.
Active component A is selected from any one triazole bactericidal agent: comparatively preferred active component is as triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, alkene azoles alcohol, Triadimenol etc.
Common feature is to contain hydroxyl (ketone group), substituted-phenyl and 1,2 on the main chain, 4-triazole group compound on the triazole bactericidal agent chemical constitution.This class medicament is except that to the oomycetes non-activity in the Mastigomycotina, and the pathogen of Ascomycotina, Basidiomycotina and Deuteromycotina is all had activity, and its mechanism of action is damaged somatic cells film function for to influence the sterols biosynthesis.
Described triazolone (triadimefon), molecular formula are C
14H
16ClN
3O
2, chemical name: 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-α-butanone.Be a kind of efficient, low toxicity, low-residual, the lasting period is long, interior absorption is strong triazole bactericidal agent.After the each several part of plant absorption, can in plant corpus, conduct.Rust and powdery mildew are had prevention, effect such as root out, treat, fumigate.All effective to the disease of various crop such as corn circle pinta, wheat class moire disease, wheat leaf rot, pineapple black rot, maize head smut etc.The bactericidal mechanism principle of triazolone mainly is to suppress the biosynthesis of thalline ergosterol, thereby the growth, the growth of mycelia and the formation of spore that suppress or disturb thalline to adhere to spore and haustorium.
Described own azoles alcohol (hexaconazole), molecular formula are C
14H
17Cl
2X
3O, chemical name: (RS)-2-(2,4 dichloro benzene base)-1-(1H-1,2,4-triazol-1-yl)-oneself-2-alcohol.
Described Tebuconazole (tebuconazole), molecular formula are C
16H
22ON
3Cl, chemical name: (RS)-and 1-is right-chlorphenyl-4, and 4-dimethyl-3 (1H-1,2,4-triazol-1-yl methyl) amylalcohol.Tebuconazole is the wide spectrum triazole bactericidal agent, and consumption is low, can be applicable to the seed treatment of wheat, to the various cause of diseases that seed carries, is adsorbed on epidermis or seed inside all equally effectively, is particularly useful for the control of smut.
Described bitertanol (bitertanol), molecular formula are C
20H
23N
3O
2, chemical name: 1-(biphenyl-4-base oxygen)-1-(1H-1,2,4-triazol-1-yl) 3,3-dimethyl butyrate-2-alcohol.Be a kind of efficient, wide-spectrum bactericide, the cuticula on porous blade face and enter plant tissue has protection and therapeutic action.Rust, powdery mildew, scab, leaf spot etc. there is the better prevention effect.
Described alkene azoles alcohol (diniconazole), molecular formula are C
15H
17C
L2N
3O, chemical name: (E)-(RS)-and 1-(2,4 dichloro benzene base)-4,4-dimethyl-2-(1,2, the 4-triazol-1-yl)-1-amylene-3-alcohol.Triazole bactericidal agent suppresses 14 α-demethylation effect in the ergosterol biosynthesis of fungi, cause that ergosterol lacks, and causes fungal cell membrane undesired, final fungi death, and the lasting period is permanent.To people and animals, useful insect, Environmental security.
Described Triadimenol (triadimenol), molecular formula are C
14H
18ClN
3O
2, chemical name: 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4 triazoles-1 base) butyl-2-alcohol.Mainly be that to suppress ergosterol synthetic, thus suppress and disturb thalline adhere to growing of spore and haustorium.
Described Cyproconazole, (having another name called cyproconazole) English name: Cyproconazole, molecular formula: C
15H
18ClN
3O, chemical name: 2-(4-chlorphenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl) fourth-2-alcohol.Be sterol demethylation inhibitor, have prevention and therapeutic action.All effective to the Erysiphales on cereal crop, coffee, beet, fruit tree and the grape, Uredinales, the mould genus of genus spore, Rhynchosporium spp, Septoria, Venturia bacterium.Use with other bactericide, can fine cereal eye spot disease, leaf spot and the net blotch of preventing and treating.The control wheat rust lasting period was 4～6 weeks, and preventing and treating powdery mildew was 3～4 weeks.Cereal, fruit tree and grape powdery mildew, peanut, beet tops pinta, apple snow mildew and peanut white rot.
Active component B is a metconazole.
The ratio of weight and number of A, two kinds of active components of B is 80: 1～1: 80, and preferred ratio of weight and number is 40: 1～1: 40, and preferred ratio of weight and number is: 20: 1～1: 20.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of active component triazolone and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains metconazole is characterized in that: the own azoles alcohol of active component is 10: 1～1: 10 with the ratio of weight and number of metconazole, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of active component Tebuconazole and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of active component Cyproconazole and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of active component bitertanol and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains metconazole is characterized in that: active component alkene azoles alcohol is 10: 1～1: 10 with the ratio of weight and number of metconazole, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains metconazole is characterized in that: the ratio of weight and number of active component Triadimenol and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 10.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 1～90% of a gross weight in the composition, and preferable is 10%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, emulsifier or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by common processing method preparation known in those skilled in the art, be about to active substance and after liquid flux or solid carrier mix, add in surfactant such as dispersant, stabilizing agent, wetting agent, binding agent, the defoamer etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand, and the wherein excellent formulation of selecting is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment.
When making wetting powder, composition comprises following constituent content: active components A 1～80%, metconazole 1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%.
Active components A, metconazole, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into wetting powder product of the present invention.
When making water dispersible granules, composition comprises following constituent content: active components A 1～80%, metconazole 1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～90%.
Active components A, metconazole, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes water dispersible granules product of the present invention.
Comprise following constituent content when composition is made suspending agent: active components A 1～40%, metconazole 1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active components A, metconazole, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes suspending agent product of the present invention.
Comprise following constituent content when composition is made aqueous emulsion: active components A 1～40%, metconazole 1～40%, solvent 1～30%, emulsifier 1～15%, co-emulsifier 0～8%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, deionized water are supplied surplus.
Above-mentioned formulation material is mixed, active ingredient, solvent, emulsifier, co-emulsifier are added together, make and be dissolved into even oil phase; Water, antifreeze, thickener, defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added oil phase, make aqueous emulsion product of the present invention.
Comprise following constituent content when composition is made microemulsion: active components A 1～40%, metconazole 1～40%, solvent 1～30%, emulsifier 3～20%, co-emulsifier 0～12%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, stabilizing agent 0～4%, deionized water is supplied surplus.
Former medicine of active components A and the former medicine of metconazole are dissolved in the homogenizer that solvent and cosolvent are housed; Mix strongly after joining emulsifier, stabilizing agent and antifreeze, water in the homogenizer that above-mentioned solution is housed and homogenize, obtain the as clear as crystal microemulsion product of the present invention of outward appearance at last.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, the aluminium chloride.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from one or more among alkyl benzene sulfonate calcium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 506#, 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80, the 602#;
Described co-emulsifier is one or more in butanols, isobutanol, dodecanol-1, tetradecanol-1, the octadecanol-1;
Described solvent is selected from one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, vegetable oil, dimethyl formamide, acetonitrile, polyethylene glycol, pyrrolidones, the solvent N-chain alkyl pyrrolidones;
Described preservative is selected from one or more in formaldehyde, sodium salicylate, Sodium Benzoate, the dichlorophen;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Microbicide compositions of the present invention has protection concurrently, treats and roots out activity, for example can be used for various crop: wheat, paddy rice, vegetables, fruit tree etc., the microbial plant disease of cause of disease of control capsule bacterium subphylum, Basidiomycotina and Deuteromycotina.Anthracnose, leaf spot, powdery mildew, rust, rice sheath blight disease, rice blast there is special efficacy.
Composition of the present invention has following advantage:
(1) said composition shows significant synergistic effect in certain ratio range, has both improved protection effect, has reduced mu dosage and cost, has enlarged fungicidal spectrum again;
(2) since in the said composition each active component do not have the problem of cross resistance, so the application of said composition can reach and delay drug-fast generation of pathogen and development, the result of use that helps to prolong this medicament reduces pesticide resistance and produces probability;
(3) improved safety, being mixed will be lower to the influence of environment, safer.
Embodiment
To further instruction of the present invention, the percentage among the embodiment is ratio of weight and number below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one: Toxicity Determination
Active components A (A be selected from triazole bactericidal agent triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, alkene azoles alcohol, the Triadimenol a kind of) is composite to target germ Toxicity Determination with metconazole
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the target germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A (triazole bactericidal agent triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, alkene azoles alcohol, Triadimenol) and metconazole shared ratio in composition;
A is a kind of in triazole bactericidal agent triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, alkene azoles alcohol, the Triadimenol;
B is a metconazole.
It is as shown in the table for result of the test:
Toxicity test result one
Table 1 triazolone, metconazole and composite toxicity test analysis of results table thereof to alternaria leaf spot of apple
As shown in Table 1, triazolone, metconazole are to the EC of alternaria leaf spot of apple
50Be respectively 2.68mg/L and 1.45mg/L.Triazolone and metconazole were mixed in the scope at 80: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result two
The own azoles alcohol of table 2, metconazole and composite toxicity test analysis of results table thereof to rice sheath blight disease
As shown in Table 2, own azoles alcohol, metconazole are to the EC of rice sheath blight disease
50Be respectively 1.21mg/L and 1.32mg/L.Own azoles alcohol is mixed in the scope at 80: 1～1: 80 with metconazole and all shows obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result three
Table 3 Cyproconazole, metconazole and composite toxicity test analysis of results table thereof to apple mildew
As shown in Table 3, Cyproconazole, metconazole are to the EC of apple mildew
50Be respectively 1.15mg/L and 1.36mg/L.Cyproconazole and metconazole were mixed in the scope at 80: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result four
Table 4 bitertanol, metconazole and composite toxicity test analysis of results table thereof to powdery mildew of cucumber
As shown in Table 4, bitertanol, metconazole are to the EC of powdery mildew of cucumber
50Be respectively 1.95mg/L and 1.27mg/L.Bitertanol and metconazole were mixed in the scope at 80: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result five
Table 5 alkene azoles alcohol, metconazole and composite toxicity test analysis of results table thereof to pear scab
As shown in Table 5, alkene azoles alcohol, metconazole are to the EC of pear scab
50Be respectively 2.16mg/L and 1.62mg/L.Alkene azoles alcohol is mixed in the scope at 80: 1～1: 80 with metconazole and all shows obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result six
Table 6 Triadimenol, metconazole and composite toxicity test analysis of results table thereof to barley powdery mildew
As shown in Table 6, Triadimenol, metconazole are to the EC of barley powdery mildew
50Be respectively 3.48mg/L and 1.59mg/L.Triadimenol and metconazole were mixed in the scope at 80: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result seven
The own azoles alcohol of table 7, metconazole and composite toxicity test analysis of results table thereof to rice sheath blight disease
As shown in Table 7, own azoles alcohol, metconazole are to the EC of rice sheath blight disease
50Be respectively 1.31mg/L and 1.35mg/L.Own azoles alcohol is mixed in the scope at 80: 1～1: 80 with metconazole and all shows obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Implementation of an application example two: field control effectiveness test
Embodiment 180% triazolone metconazole wetting powder is prevented and treated the wheat rust test of pesticide effectiveness
Triazolone 65%, metconazole 15%, polycarboxylate 5%, lauryl sodium sulfate 3%, spaonin powder 2%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 80% triazolone metconazole wetting powder.This proportioning is by 20 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the wheat rust effect in 7 days, 14 days behind the medicine and be respectively 91.2%, 96.6%, 25% trazodone wettable powder and 60g/L metconazole water and milk are according to same quadrat method, use by 35 gram/mus and the dilution of 30 gram/mus respectively, 14 days preventive effects are respectively 65.2% and 73.8% behind the medicine.
In the present embodiment triazolone replaceable be a kind of in Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, alkene azoles alcohol, the Triadimenol, thereby form new embodiment.
Embodiment 240% Cyproconazole metconazole aqueous emulsion is prevented and treated the sigatoka test of pesticide effectiveness
Cyproconazole 30%, metconazole 10%, methyl alcohol 8%, alkylphenol polyoxyethylene phosphate 5%, polyethylene glycol 3%, alkyl benzene calcium sulfonate 5%, sodium chloride 2%, deionized water add to 100%, the mixed 40% Cyproconazole metconazole aqueous emulsion that gets.This proportioning is by 4000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the sigatoka effect in 7 days, 14 days behind the medicine and be respectively 91.2%, 95.6%, 40% Cyproconazole wetting powder and 60g/L metconazole water and milk are according to same quadrat method, use by 60 gram/mus and the dilution of 30 gram/mus respectively, 14 days preventive effects are respectively 68.8% and 71.6% behind the medicine.
In the present embodiment Cyproconazole replaceable be a kind of in triazolone, Tebuconazole, own azoles alcohol, bitertanol, alkene azoles alcohol, the Triadimenol, thereby form new embodiment.
Embodiment 340% own azoles alcohol metconazole suspension emulsion is prevented and treated the rice sheath blight disease test of pesticide effectiveness
Own azoles alcohol 10%, metconazole 30%, polycarboxylate 3%, lignosulfonates 3%, neopelex 4%, polyoxyethylene nonylphenol ether modified phosphate 3%, acetone 6%, xanthans 0.5%, ethylene glycol 4%, deionized water add to 100%, the mixed 40% own azoles alcohol metconazole suspension emulsion that gets.This proportioning is by 30 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the rice sheath blight disease drug effect in 7 days, 14 days behind the medicine and really be respectively 91.3%, 95.8%, 10% hexaconazole suspending agent and 60g/L metconazole water and milk are according to same quadrat method, use by 50 gram/mus and the dilution of 30 gram/mus respectively, 14 days preventive effects are respectively 72.8% and 71.6% behind the medicine.
In the present embodiment own azoles alcohol replaceable be a kind of in triazolone, Tebuconazole, Cyproconazole, bitertanol, alkene azoles alcohol, the Triadimenol, thereby form new embodiment.
Embodiment 448% alkene azoles alcohol metconazole microemulsion is prevented and treated the apple mildew test of pesticide effectiveness
Alkene azoles alcohol 40%, metconazole 8%, acetone 12%, agricultural newborn 600#8%, isobutanol 5%, hydroxyethylcellulose 2%, sodium sorbate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, the mixed 48% alkene azoles alcohol metconazole microemulsion that gets.This proportioning is by 3500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevented and treated the apple mildew effect behind the medicine in 7 days, 14 days and be respectively 90.3%, 95.3%, 10% alkene azoles alcohol missible oil and 60g/L metconazole water and milk according to same quadrat method, dilute 800 times and 600 times of uses respectively, 14 days preventive effects are respectively 66.3% and 73.4% behind the medicine.
In the present embodiment alkene azoles alcohol replaceable be a kind of in triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, the Triadimenol, thereby form new embodiment.
Embodiment 560% Tebuconazole metconazole water dispersible granules is prevented and treated the pear scab test of pesticide effectiveness
Tebuconazole 50%, metconazole 10%, alkyl benzene sulfonate calcium salt 4%, sodium phosphate trimer 3%, wetting and penetrating agent F 3%, ammonium sulfate 1%, bentonite add to 100%, the mixed 60% Tebuconazole metconazole water dispersible granules that gets.This proportioning is by 2000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the pear scab effect in 7 days, 14 days behind the medicine and be respectively 91.7%, 96.9%, 25% Tebuconazole wetting powder and 60g/L metconazole water and milk are according to same quadrat method, dilute 1500 times and 800 respectively by the spraying use, 14 days preventive effects are respectively 68.4% and 71.6% behind the medicine.
In the present embodiment Tebuconazole replaceable be a kind of in triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, the alkene azoles alcohol, thereby form new embodiment.
The embodiment 645% bitertanol metconazole suspending agent control beet powdery mildew test of pesticide effectiveness
Bitertanol 40%, metconazole 5%, polycarboxylate 4%, sodium lignin sulfonate 3%, DBSA 4%, silicone oil 0.1%, polyvinyl alcohol 0.3%, deionized water adds to 100%, the mixed 45% bitertanol metconazole suspending agent that gets.This proportioning is by 18 gram/mus dilution spraying, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control beet powdery mildew drug effects really are respectively 91.7%, 97.1% behind the medicine, 50% bitertanol wetting powder and 60g/L metconazole water and milk are according to same quadrat method, use by 13 gram/mus and 30 gram/mus dilution spraying respectively, 14 days preventive effects are respectively 67.5% and 72.8% behind the medicine.
In the present embodiment bitertanol replaceable be a kind of in triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, alkene azoles alcohol, the Triadimenol, thereby form new embodiment.
Embodiment 710% Triadimenol metconazole seed treatment is handled the wheat seed test
Triadimenol 5%, metconazole 5%, polycarboxylate 4%, sodium lignin sulfonate 3%, dichlorophen 3%, salicylate 2%, alkyl benzene sulfonate calcium salt 3%, deionized water adds to 100%, the mixed 10% Triadimenol metconazole seed treatment that gets.This proportioning is pressed 45g/100kg seed seed dressing, in closed container, seed dressing was mixed 1 minute with the seed jolting, with planting seed to the experimental field, and laggard pedestrian worker's irrigation in one day.After planting 28 days calculate preventive effect is 100%, does not observe and infects.Contrast medicament 25% Triadimenol seed dressing and 10% metconazole seed dressing calculated preventive effect and are respectively 85.4%, 83.6% by using with quadrat method in after planting 28 days.
In the present embodiment Triadimenol replaceable be a kind of in triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, the alkene azoles alcohol, thereby form new embodiment.
The ratio of A, two kinds of active components of B can be adjusted in 80: 1～1: 80 synergy scope in the foregoing description, thereby forms new embodiment.
Claims (6)
1. bactericidal composition that contains metconazole and triazole type is characterized in that: a kind of and (B) ratio of weight and number of metconazole in two kinds of active components (A) triazole bactericidal agent is 80: 1～1: 80.
2. the bactericidal composition that contains metconazole and triazole type according to claim 1 is characterized in that: described triazole bactericidal agent is selected from a kind of in triazolone, Tebuconazole, own azoles alcohol, Cyproconazole, bitertanol, alkene azoles alcohol, the Triadimenol.
3. the bactericidal composition that contains metconazole and triazole type according to claim 1 is characterized in that: the ratio of weight and number of two kinds of active component A and B is 20: 1～1: 20.
4. according to the described bactericidal composition that contains metconazole and triazole type of claim 3, it is characterized in that: the own azoles alcohol of active component is 10: 1～1: 10 with the ratio of weight and number of metconazole;
The ratio of weight and number of active component Tebuconazole and metconazole is 10: 1～1: 10;
The ratio of weight and number of active component Cyproconazole and metconazole is 10: 1～1: 10;
The ratio of weight and number of active component bitertanol and metconazole is 10: 1～1: 10;
Active component alkene azoles alcohol is 10: 1～1: 10 with the ratio of weight and number of metconazole;
The ratio of weight and number of active component Triadimenol and metconazole is 10: 1～1: 10;
The ratio of weight and number of active component triazolone and metconazole is 10: 1～1: 10.
5. the bactericidal composition that contains metconazole and triazole type according to claim 1 is characterized in that: the weight percentage of active component is 5%～85% of a gross weight in the composition.
6. the bactericidal composition that contains metconazole and triazole type according to claim 5 is characterized in that: the weight percentage of active component is 10%～80% of a gross weight in the composition.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103688945A (en) * | 2013-12-10 | 2014-04-02 | 济南凯因生物科技有限公司 | Composition for controlling wheat powdery mildew |
| CN105918324A (en) * | 2016-05-06 | 2016-09-07 | 江苏丰登作物保护股份有限公司 | Fungicidal composition containing metconazole and cyproconazole and application thereof |
| CN106172421A (en) * | 2016-07-05 | 2016-12-07 | 南京农业大学 | A kind of containing metconazole and the bactericidal composition of Tebuconazole and application |
| CN106332888A (en) * | 2016-08-25 | 2017-01-18 | 陕西西大华特科技实业有限公司 | Seed treatment agent and preparation method thereof |
| CN109169681A (en) * | 2018-10-25 | 2019-01-11 | 江苏生久农化有限公司 | Composition and its preparation method and application containing metconazole and Tebuconazole |
| CN109362769A (en) * | 2018-11-12 | 2019-02-22 | 安徽农业大学 | A kind of bactericidal composition and its application containing Diacloden, metconazole and olefin conversion |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103688945A (en) * | 2013-12-10 | 2014-04-02 | 济南凯因生物科技有限公司 | Composition for controlling wheat powdery mildew |
| CN105918324A (en) * | 2016-05-06 | 2016-09-07 | 江苏丰登作物保护股份有限公司 | Fungicidal composition containing metconazole and cyproconazole and application thereof |
| CN106172421A (en) * | 2016-07-05 | 2016-12-07 | 南京农业大学 | A kind of containing metconazole and the bactericidal composition of Tebuconazole and application |
| CN106332888A (en) * | 2016-08-25 | 2017-01-18 | 陕西西大华特科技实业有限公司 | Seed treatment agent and preparation method thereof |
| CN109169681A (en) * | 2018-10-25 | 2019-01-11 | 江苏生久农化有限公司 | Composition and its preparation method and application containing metconazole and Tebuconazole |
| CN109362769A (en) * | 2018-11-12 | 2019-02-22 | 安徽农业大学 | A kind of bactericidal composition and its application containing Diacloden, metconazole and olefin conversion |
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Address after: 715500 Pucheng County of Shaanxi Province agricultural base industrial park Applicant after: Shaanxi Meibang Pesticide Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Applicant before: Shaanxi Meibang Pesticide Co., Ltd. |
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Application publication date: 20110427 |