CN101999363B - Disinfectant composition containing fenoxanil and triazoles - Google Patents
Disinfectant composition containing fenoxanil and triazoles Download PDFInfo
- Publication number
- CN101999363B CN101999363B CN 201010571343 CN201010571343A CN101999363B CN 101999363 B CN101999363 B CN 101999363B CN 201010571343 CN201010571343 CN 201010571343 CN 201010571343 A CN201010571343 A CN 201010571343A CN 101999363 B CN101999363 B CN 101999363B
- Authority
- CN
- China
- Prior art keywords
- rice blast
- acid amides
- blast acid
- penconazole
- rice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention discloses a disinfectant composition. The disinfectant composition comprises one of fenoxanil and triazole disinfectant with a synergistic effective dose, wherein the weight ratio of the two active ingredients in the disinfectant composition is 80:1-1:80. The disinfectant composition of the invention at least comprises one surfactant for dispersing the active ingredients in water during application. The disinfectant composition of the invention synchronously has the functions of protecting, controlling and eliminating activity and is mainly applied to the control of rice diseases.
Description
Technical field
The invention belongs to the disinfectant use in agriculture field, relate to a kind of preparation and application that contains the bactericidal composition of two active components.
Background technology
Rice blast acid amides (fenoxanil) is the acid amide fungicides of the common exploitation of BASF and Japanese agricultural chemicals company, and molecular formula is C
15H
18Cl
2N
2O
2, chemical name: N-(1-itrile group-1,2-dimethyl propyl)-2-(2,4-dichlorophenoxy) propionamide, structural formula is:
The rice blast acid amides is inhaled and residual activity in having well, is melanin (melanin) biosynthesis inhibitor.Be mainly used in preventing and treating rice blast, to crop, mammal, Environmental security.
The agent of rice blast acid amides list is used for a long time, and disease is developed immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.
Summary of the invention
The objective of the invention is to propose a kind of generation or delaying drug resistance speed that can prevent disease drug resistance, the bactericidal composition that contains the rice blast acid amides that use cost is low, preventive effect is good.
The inventor is by a large amount of indoor biometricses and field control effectiveness test, finds the use that is mixed within the specific limits of rice blast acid amides and triazole bactericidal agent unexpectedly, and rice blast is had good synergistic effect.Further experiment finds, the use that is mixed within the specific limits of rice blast acid amides and triazole bactericidal agent also has good preventive effect to rice sheath blight disease, false smut.And the composite of rice blast acid amides and triazole bactericidal agent at home and abroad do not see openly as yet.
The bactericidal composition that the present invention proposes contains two kinds of active components of A, B.
Active component A is selected from any one triazole bactericidal agent: comparatively preferred active component is Flutriafol, penconazole, tetraconazole, RH-7592.
Common feature is to contain hydroxyl (ketone group), substituted-phenyl and 1,2,4-triazole group compound on the main chain on the triazole bactericidal agent chemical constitution.This class medicament is except to the oomycetes non-activity in the Mastigomycotina, and the pathogen of Ascomycotina, Basidiomycotina and Deuteromycotina is all had activity, and its mechanism of action is damaged somatic cells film function for to influence the sterols biosynthesis.
Described tetraconazole (tetraconazole), molecular formula are C
13H
11Cl
2F
4N
3O, chemical name: 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl) propyl group 1,1,2,2-tetrafluoro ethyl ether.
Described Flutriafol (flutriafol), molecular formula are C
16H
13F
2N
30, chemical name: α-(2-fluorophenyl)-α-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol.Have interior absorption, in plant corpus, conduct, disease is had protection and therapeutic action.Can prevent and treat the cereal crop powdery mildew, Helminthosporium, Puccinia, shell pin Pseudomonas pathogen also can be cooked seed treatment, prevents and treats soil-borne disease and seed-borne disease.The cereal powdery mildew there is special efficacy.
Described penconazole (penconazole), molecular formula are C
13H
15Cl
2N
3, chemical name: 1-[2-(2,4-dichlorophenyl)-4-propyl group-1,3-dioxolanes-2-methyl]-1-hydrogen-1,2, the 4-triazole.Belonging to three nitrogen heterocycles bactericide, is sterol demethylation inhibitor.Root, stem, leaf isoreactivity tissue by crop absorb, and can upwards conduct with body fluid in the plant body soon.
Described RH-7592 (fenbuconazole), molecular formula are C
19H
17ClN
4, chemical name: 4-(4-chlorphenyl)-2-phenyl-2 (1H-1,2,4-triazol-1-yl methyl) butyronitrile.Belong to ergosterol biosynthesis inhibitor (EBI).Have protection concurrently, cure the disease and the interior absorption wide-spectrum bactericide of killing action.
Active component B is the rice blast acid amides.
The ratio of weight and number of A, two kinds of active components of B is 80: 1～1: 80, and preferred ratio of weight and number is 40: 1～1: 40, and preferred ratio of weight and number is: 20: 1～1: 20, further preferred ratio of weight and number was 10: 1～1: 10.
The described bactericidal composition that contains the rice blast acid amides is characterized in that: the percentage by weight of active component penconazole and rice blast acid amides is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 10.
The described bactericidal composition that contains the rice blast acid amides is characterized in that: the percentage by weight of active component Flutriafol and rice blast acid amides is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The described bactericidal composition that contains the rice blast acid amides is characterized in that: the percentage by weight of active component tetraconazole and rice blast acid amides is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The described bactericidal composition that contains the rice blast acid amides is characterized in that: the percentage by weight of active component RH-7592 and rice blast acid amides is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
Amount of application when the content of active component depends on independent use in the present composition also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 1～90% of gross weight in the composition, and preferable is 10%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, emulsifier or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by common processing method preparation known in those skilled in the art, be about to active substance and after liquid flux or solid carrier mix, add in surfactant such as dispersant, stabilizing agent, wetting agent, binding agent, the defoamer etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand, and wherein the excellent formulation of selecting is: wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment.
When making wetting powder, composition comprises following constituent content: triazole class compounds 1～80%, rice blast acid amides 1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%.
Triazole class compounds, rice blast acid amides, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, namely can be made into wetting powder product of the present invention.
When making water dispersible granules, composition comprises following constituent content: triazole class compounds 1～80%, rice blast acid amides 1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～90%.
Triazole class compounds, rice blast acid amides, dispersant, wetting agent, disintegrant, filler etc. are pulverized the particle diameter that obtains needs through air-flow together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes water dispersible granules product of the present invention.
Comprise following constituent content when composition is made suspending agent: triazole class compounds 1～40%, rice blast acid amides 1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active components A, rice blast acid amides, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes suspending agent product of the present invention.
Comprise following constituent content when composition is made suspension emulsion: triazole class compounds 1～50%, active component B 1～50%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned formulation material are mixed through high speed shear, add the rice blast acid amides, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make rice blast acid amides suspending agent, then with triazole class compounds, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.
Comprise following constituent content when composition is made aqueous emulsion: triazole class compounds 1～40%, rice blast acid amides 1～40%, solvent 1～30%, emulsifier 1～15%, co-emulsifier 0～8%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, deionized water are supplied surplus.
Above-mentioned formulation material is mixed, active ingredient, solvent, emulsifier, co-emulsifier are added together, make and be dissolved into even oil phase; Water, antifreeze, thickener, defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added oil phase, make aqueous emulsion product of the present invention.
Comprise following constituent content when composition is made microemulsion: triazole class compounds 1～40%, rice blast acid amides 1～40%, solvent 1～30%, emulsifier 3～20%, co-emulsifier 0～12%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, stabilizing agent 0～4%, deionized water is supplied surplus.
Triazole class compounds and the former medicine of rice blast acid amides are dissolved in the homogenizer that solvent and cosolvent are housed; Mix strongly after joining emulsifier, stabilizing agent and antifreeze, water in the homogenizer that above-mentioned solution is housed and homogenize, obtain the as clear as crystal microemulsion product of the present invention of outward appearance at last.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, the aluminium chloride.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from one or more among alkyl benzene sulfonate calcium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 506#, 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80, the 602#;
Described co-emulsifier is one or more in butanols, isobutanol, dodecanol-1, tetradecanol-1, the octadecanol-1;
Described solvent is selected from one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, vegetable oil, dimethyl formamide, acetonitrile, polyethylene glycol, pyrrolidones, the solvent N one chain alkyl pyrrolidones;
Described preservative is selected from one or more in formaldehyde, sodium salicylate, Sodium Benzoate, the dichlorophen;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Microbicide compositions of the present invention has protection concurrently, treats and roots out activity, for example can be used for various crop: wheat, paddy rice, vegetables, fruit tree etc., the microbial plant disease of cause of disease of control capsule bacterium subphylum, Basidiomycotina and Deuteromycotina.To the disease on the cereal crop as: powdery mildew, rust, rice sheath blight disease, rice blast have special efficacy.
Composition of the present invention has following advantage:
(1) said composition shows significant synergistic effect in certain ratio range, has both improved protection effect, has reduced mu dosage and cost, has enlarged fungicidal spectrum again;
(2) since in the said composition each active component do not have the problem of cross resistance, so the application of said composition can reach and delay the drug-fast generation of pathogen and development, the result of use that helps to prolong this medicament reduces pesticide resistance and produces probability;
(3) improved safety, being mixed will be lower to the influence of environment, safer.
Embodiment
Below in conjunction with the further instruction of the present invention of embodiment, the percentage among the embodiment all is weight percentage, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one: Toxicity Determination
Active components A (A be selected from triazole bactericidal agent Flutriafol, penconazole, tetraconazole, the RH-7592 a kind of) is composite to the rice blast Toxicity Determination with the rice blast acid amides
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure medicament to the virulence of rice blast.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A (triazole bactericidal agent Flutriafol, penconazole, tetraconazole, RH-7592) and rice blast acid amides shared ratio in combination;
A is a kind of in triazole bactericidal agent Flutriafol, penconazole, tetraconazole, the RH-7592;
B is the rice blast acid amides.
It is as shown in the table for result of the test:
Toxicity test result one
Table 1 penconazole, rice blast acid amides and composite toxicity test analysis of results table to rice blast thereof
As shown in Table 1, penconazole, rice blast acid amides are to the EC of rice blast
50Be respectively 0.086mg/L and 0.435mg/L.The virulence of penconazole is higher than the virulence of rice blast acid amides.Penconazole and rice blast acid amides were mixed in the scope at 40: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 10: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 5: 1～1: 10 scope.
Toxicity test result two
Table 2 Flutriafol, rice blast acid amides and composite toxicity test analysis of results table to rice blast thereof
As shown in Table 2, Flutriafol, rice blast acid amides are to the EC of rice blast
50Be respectively 0.152mg/L and 0.435mg/L.The virulence of Flutriafol is higher than the virulence of rice blast acid amides.Flutriafol and rice blast acid amides were mixed in the scope at 80: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result three
Table 3 tetraconazole, rice blast acid amides and composite toxicity test analysis of results table to rice blast thereof
As shown in Table 3, tetraconazole, rice blast acid amides are to the EC of rice blast
50Be respectively 0.094mg/L and 0.435mg/L.The virulence of tetraconazole is higher than the virulence of rice blast acid amides.Tetraconazole and rice blast acid amides were mixed in the scope at 40: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 40 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Toxicity test result four
Table 4 RH-7592, rice blast acid amides and composite toxicity test analysis of results table to rice blast thereof
As shown in Table 4, RH-7592, rice blast acid amides are to the EC of rice blast
50Be respectively 0.096mg/L and 0.435mg/L.The virulence of RH-7592 is higher than the virulence of rice blast acid amides.RH-7592 and rice blast acid amides were mixed in the scope at 40: 1～1: 80 and all show obvious synergistic effect.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and mixed synergies is particularly outstanding in 10: 1～1: 10 scope.
Implementation of an application example two: the implementation of Formulation Example
Embodiment 1 80% rice blast acid amides Flutriafol water dispersible granules
Rice blast acid amides 60%, Flutriafol 20%, alkylphenol-polyethenoxy are phonetic 3%, lignosulfonates 3%, lauryl sodium sulfate 4%, starch 5%, kaolin add to 100%, mixed 80% rice blast acid amides Flutriafol water dispersible granules.
Embodiment 2 70% rice blast acid amides penconazole water dispersible granules
Rice blast acid amides 60%, penconazole 10%, polycarboxylate 3%, polyoxyethylene carboxylate 3%, lauryl sodium sulfate 4%, sodium bicarbonate 3%, starch 7%, kaolin add to 100%, the mixed 70% rice blast acid amides penconazole water dispersible granules that gets.
Embodiment 3 60% rice blast acid amides tetraconazole water dispersible granules
Rice blast acid amides 50%, tetraconazole 10%, alkylphenol-polyethenoxy are phonetic 5%, dodecyl benzene sulfonate 3%, starch 18%, bentonite add to 100%, mixed 60% rice blast acid amides tetraconazole water dispersible granules.
Embodiment 4 65% rice blast acid amides RH-7592 water dispersible granules
Rice blast acid amides 50%, RH-7592 15%, polycarboxylate 3%, sodium lignin sulfonate 2%, lauryl sodium sulfate 4%, urea 3%, starch 5%, kaolin add to 100%, the mixed 65% rice blast acid amides RH-7592 water dispersible granules that gets.
Embodiment 5 40% rice blast acid amides Flutriafol suspending agents
Rice blast acid amides 30%, Flutriafol 10%, alkyl benzene sulfonate calcium salt 5%, Sodium Polyacrylate 2%, DBSA 4%, silicone oil 0.1%, xanthan gum 0.3%, phenyl phenol polyoxy ethyl ether 2%, deionized water adds to 100%, the mixed 40% rice blast acid amides Flutriafol suspending agent that gets.
Embodiment 6 40% rice blast acid amides RH-7592 suspending agents
Rice blast acid amides 20%, RH-7592 20%, alkyl benzene sulfonate calcium salt 5%, Sodium Polyacrylate 2%, DBSA 4%, silicone oil 0.1%, xanthan gum 0.3%, phenyl phenol polyoxy ethyl ether 2%, deionized water adds to 100%, the mixed 40% rice blast acid amides RH-7592 suspending agent that gets.
Embodiment 7 48% rice blast acid amides penconazole suspension emulsions
Rice blast acid amides 8%, Flutriafol 40%, alkylbenzenesulfonate 8%, polycarboxylate 4%, soapberry powder 5%, organosilicon 0.1%, hydroxyethylcellulose 0.1%, ethylene glycol 2%, alkyl benzene calcium sulfonate 2%, deionized water adds to 100%, the mixed 48% rice blast acid amides Flutriafol suspension emulsion that gets.
Embodiment 8 30% rice blast acid amides tetraconazole suspension emulsions
Rice blast acid amides 20%, tetraconazole 10%, castor oil polyoxyethylene ether 6%, polycarboxylate 2%, Nekal BX 2%, C
10-20Saturated fat acid compounds 0.1%, polyethylene glycol 0.5%, ethylene glycol 4%, deionized water adds to 100%, the mixed 30% rice blast acid amides tetraconazole suspension emulsion that gets.
Embodiment 9 40% rice blast acid amides penconazole aqueous emulsions
Rice blast acid amides 10%, penconazole 30%, ethyl acetate 20%, acetonitrile 5%, castor oil polyoxyethylene ether 5%, polyvinyl alcohol 1%, propane diols 5%, lauric acid 0.5%, deionized water adds to 100%, the mixed 40% rice blast acid amides penconazole aqueous emulsion that gets.
Embodiment 10 36% rice blast acid amides Flutriafol aqueous emulsions
Rice blast acid amides 6%, Flutriafol 30%, methyl alcohol 18%, acetone 8%, alkylphenol polyoxyethylene 5%, polyvinyl alcohol 1%, glycerine 5%, silicone oil 0.5%, deionized water adds to 100%, the mixed 36% rice blast acid amides Flutriafol aqueous emulsion that gets.
Embodiment 11 30% rice blast acid amides tetraconazole aqueous emulsions
Rice blast acid amides 20%, tetraconazole 10%, methyl alcohol 15%, dimethyl sulfoxide (DMSO) 8%, fatty alcohol-polyoxyethylene ether 5%, xanthans 1%, glycerine 5%, aluminium-magnesium silicate 0.3%, deionized water adds to 100%, the mixed 30% rice blast acid amides tetraconazole aqueous emulsion that gets.
Embodiment 12 30% rice blast acid amides RH-7592 aqueous emulsions
Rice blast acid amides 20%, RH-7592 10%, methyl alcohol 15%, toluene 8%, fatty alcohol-polyoxyethylene ether 5%, xanthans 1%, glycerine 5%, aluminium-magnesium silicate 0.3%, deionized water adds to 100%, the mixed 30% rice blast acid amides RH-7592 aqueous emulsion that gets.
Embodiment 13 30% rice blast acid amides penconazole microemulsions
Rice blast acid amides 15%, penconazole 15%, acetonitrile 20%, alkylphenol-formaldehyde resin polyoxy ethyl ether 8%, butanols 5%, hydroxyethylcellulose 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, the mixed 30% rice blast acid amides penconazole microemulsion that gets.
Embodiment 14 25% rice blast acid amides tetraconazole microemulsions
Rice blast acid amides 10%, tetraconazole 15%, methyl alcohol 15%, phenethyl phenol polyethenoxy ether 8%, tetradecanol-15%, polyvinyl alcohol 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, the mixed 25% rice blast acid amides tetraconazole microemulsion that gets.
Embodiment 15 20% rice blast acid amides Flutriafol microemulsions
Rice blast acid amides 10%, Flutriafol 10%, ethyl acetate 12%, castor oil polyoxyethylene ether 8%, isobutanol 5%, hydroxyethylcellulose 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, the mixed 20% rice blast acid amides rice blast acid amides microemulsion that gets.
Embodiment 16 30% rice blast acid amides RH-7592 microemulsions
Rice blast acid amides 15%, RH-7592 15%, acetone 18%, alkylphenol-formaldehyde resin polyoxy ethyl ether 8%, butanediol 5%, hydroxyethylcellulose 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, the mixed 30% rice blast acid amides RH-7592 microemulsion that gets.
The ratio of rice blast acid amides and Flutriafol, penconazole, RH-7592, tetraconazole can be adjusted in 20: 1～1: 40 synergy scope in the above-mentioned the implementation of Formulation Example, thereby forms new the implementation of Formulation Example.
Embodiment uses three bactericidal compositions that contain the rice blast acid amides and prevents and treats the rice blast test of pesticide effectiveness
This experimental establishment is in Yibin City Gao County, Sichuan Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 20% rice blast acid amides suspending agent (commercial), 50% Flutriafol wetting powder (commercial), 24% RH-7592 suspending agent (commercial).4% tetraconazole aqueous emulsion (commercial).10% penconazole missible oil (commercial),
The investigation rice blast state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 3 times.Investigate the rice blast disease index respectively in 7 days, 14 days, 30 days after the last dispenser and calculate preventive effect.Experimental result is as follows:
Table 3 contains the bactericidal composition control rice blast test of pesticide effectiveness of rice blast acid amides
As can be seen from Table 3, can effectively prevent and treat rice blast after rice blast acid amides and Flutriafol, RH-7592 are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication target crop is had no adverse effects, and rice green smut is had good preventive effect, preventive effect reaches more than 90%.Embodiment uses four bactericidal compositions that contain the rice blast acid amides and prevents and treats the rice sheath blight disease test of pesticide effectiveness
This experimental establishment is in Yibin City Yibin County, Sichuan Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 20% rice blast acid amides suspending agent (commercial), 4% tetraconazole aqueous emulsion (commercial), 10% penconazole missible oil (commercial).
The investigation rice sheath blight disease state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 3 times.Investigate the rice sheath blight disease disease index respectively in 7 days, 14 days, 30 days after the last dispenser and calculate preventive effect.Experimental result is as follows:
Table 3 contains the bactericidal composition of rice blast acid amides and prevents and treats the rice sheath blight disease test of pesticide effectiveness
As can be seen from Table 3, can effectively prevent and treat rice sheath blight disease after rice blast acid amides and tetraconazole, penconazole are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication, the target crop is had no adverse effects.
Claims (7)
1. bactericidal composition that contains rice blast acid amides and triazole class compounds, it is characterized in that: the weight ratio of active component penconazole and rice blast acid amides is 80 ︰, 1 ~ 1 ︰ 80.
2. bactericidal composition according to claim 1, it is characterized in that: the weight ratio of active component penconazole and rice blast acid amides is 40 ︰, 1 ~ 1 ︰ 40.
3. according to the bactericidal composition of claim 2, it is characterized in that: the weight ratio of active component penconazole and rice blast acid amides is 20 ︰, 1 ~ 1 ︰ 20.
4. according to the bactericidal composition of claim 3, it is characterized in that: the weight ratio of active component penconazole and rice blast acid amides is 10 ︰, 1 ~ 1 ︰ 10.
5. bactericidal composition according to claim 1, it is characterized in that: the weight percentage of active component is 10%～80% of gross weight in the composition.
6. according to any described bactericidal composition in the claim 1 to 5, it is characterized in that: composition is made water dispersible granules, suspending agent, aqueous emulsion, microemulsion.
7. bactericidal composition according to claim 1 is used for the purposes of rice sheath blight disease, rice blast, false smut on the control cereal crop.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010571343 CN101999363B (en) | 2010-12-02 | 2010-12-02 | Disinfectant composition containing fenoxanil and triazoles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010571343 CN101999363B (en) | 2010-12-02 | 2010-12-02 | Disinfectant composition containing fenoxanil and triazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101999363A CN101999363A (en) | 2011-04-06 |
| CN101999363B true CN101999363B (en) | 2013-10-09 |
Family
ID=43807252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010571343 Expired - Fee Related CN101999363B (en) | 2010-12-02 | 2010-12-02 | Disinfectant composition containing fenoxanil and triazoles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101999363B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102150683B (en) * | 2011-03-03 | 2013-10-09 | 陕西美邦农药有限公司 | Fenbuconazole-containing synergic sterilization composition |
| CN103081920B (en) * | 2011-11-04 | 2014-06-04 | 深圳诺普信农化股份有限公司 | Sterilizing composition containing penconazole |
| CN102754661A (en) * | 2012-07-31 | 2012-10-31 | 潘登 | Combination fungicide for controlling rice blast and using method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101397347B (en) * | 2007-09-27 | 2011-03-23 | 北京师范大学 | High intensity hydrogel, preparation method and use thereof |
| CN101690483B (en) * | 2009-06-27 | 2012-11-14 | 深圳诺普信农化股份有限公司 | Bactericidal composition containing triazole class compounds |
-
2010
- 2010-12-02 CN CN 201010571343 patent/CN101999363B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101999363A (en) | 2011-04-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102204541B (en) | Synergetic antibacterial composition containing trifloxystrobin | |
| CN103766350A (en) | Bactericidal composition containing trifloxystrobin and tebuconazole | |
| CN102258043A (en) | Germicide composition containing protioconazole | |
| CN101790986B (en) | Fungicide composite containing tricyclazole and hexaconazole | |
| CN102177902A (en) | Synergetic sterilization composition containing pyraclostrobin | |
| CN102150678A (en) | Sterilization composition containing prochloraz | |
| CN102239855A (en) | Bactericidal composition containing trifloxystrobin and triazole | |
| CN102258049A (en) | Pesticidal composition containing prothioconazole and triazole | |
| CN102027937A (en) | Bactericidal composition containing metconazole and triazole | |
| CN101999363B (en) | Disinfectant composition containing fenoxanil and triazoles | |
| CN102150672B (en) | Sterilization composite containing orthocide and triazole compounds | |
| CN101983563A (en) | Bactericidal composite and applications thereof | |
| CN102204542A (en) | Bactericidal composition containing enostroburin and triazole compound | |
| CN102113489B (en) | Bactericidal composition containing metconazole | |
| CN102273462A (en) | Novel pesticide composition containing prothioconazole and triazoles | |
| CN102150660B (en) | Sterilization composition containing tetraconazole | |
| CN103766348A (en) | Bactericidal composition containing picoxystrobin and propiconazole | |
| CN102177911A (en) | Sterilizing composition containing penconazole | |
| CN102017956A (en) | Pesticide composition containing bitertanol | |
| CN102150683B (en) | Fenbuconazole-containing synergic sterilization composition | |
| CN103749467A (en) | Sterilization composition containing metconazole | |
| CN102172238B (en) | Synergetic sterilization composite containing ipconazole and triazole | |
| CN102077839A (en) | Antibacterial composition containing ipconazole and triazole compounds | |
| CN102150664A (en) | Penconazole-containing pesticide composition | |
| CN102037975A (en) | Sterilization composition containing triticonazole and triazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP02 | Change in the address of a patent holder |
Address after: 715500 Pucheng County of Shaanxi Province agricultural base industrial park Patentee after: Shaanxi Meibang Pesticide Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Patentee before: Shaanxi Meibang Pesticide Co., Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131009 Termination date: 20171202 |