A kind of plant fragrance preparation that promotes psychosoma harmony degree and preparation method thereof
Technical field
The invention belongs to the technical field of plant fragrance preparation, relate to the plant fragrance preparation of a kind of promote people body-centered body harmony degree and the method that microbial fermentation technology prepares the plant fragrance preparation.
Background technology
The competition of school work, employment, occupation is spirit and the psychological pressure that the modern need face, various unhealthy emotions such as normal engender tension, anxiety, depression, and these unhealthy emotions not only influence the quality of life, it is not normal more the people to be brought into play, and especially often is not difficult to show true horizon and misses opportunity because mood regulation and control are not good in activities such as examination, match, application, speech, performance.Psychology and behavior intervention are treated, some chemicalses or the Chinese materia medica method can play unhealthy emotions such as overcoming anxiety, anxiety, depression to a certain extent, but in the time of these method keeping tensions downs, may cause the active decline of neural system, human body is in " psychosoma is loosened " state, influences performance.Therefore, also lack a kind of effective solution of taking into account keeping tensions down and raising performance at present.Simultaneously, present these alternative methods also because of time-consuming, need professional person's consultation guidance, drug administration inconvenience or have untoward reaction etc. to be difficult to be accepted by masses.
The U.S. HeartMath heart can the research institute researchist find that " psychosoma harmony " state is best work, study and answering pressure challenge state.Under this kind state, the multiple physiological system of health is in orderly running and physiology resonance state as rhythm of the heart pattern, autonomic nervous system, brain function, breathing and the blood pressure rhythm and pace of moving things etc.; Psychological aspects people's mood also is to be in actively front state such as optimism, appreciation.Therefore, " psychosoma harmony " state is psychology and physiological harmonious state, is the maximized state of allomeric function.Under this state, our physiological system operation more effectively, mood is more stable, and clear thinking, cognitive function improve, and helps to learn expeditiously, work and answering pressure challenge.Promote the technology and the plant and instrument that reach this kind state to be applied to cosmonaut, training athlete and student's education abroad.At present, the emWave PC system of HeartMath exploitation can measure psychosoma harmony degree by detecting heart rate variability (HRV) index.
Plant component aromatic preparation is existing long historical, is widely used in industries such as health care, cosmetics at present.Some of them plant fragrance preparation has effects such as clear and definite alleviating fatigue, calmness, beauty treatment.Plant medicine (Planta Med. 2004 Jul; 70 (7): 632-6) magazine report Yilan (Cananga odorata) essential oil has the mood of loosening, chills out, relaxes heartbeat and breathing, effect such as hypotensive grade; International aromatotherapy magazine (The International Journal of Aromatherapy, 2006) report Rome Flos Matricariae chamomillae essential oil preparation has the feelings will of improving the people and the effect of cognitive function; The research (Holist Nurs Pract, 2009) that U.S. holistic Nursing association subsidizes finds that also Herba Lysimachiae foenumgraeci quintessence oil and rosemary ethereal oil have effects such as the examination anxiety of alleviation and hypermnesis respectively.Patent CN 101164560 discloses a kind of plant component aromatic preparation, comprise the volatile oil of producing by the bighead atractylodes rhizome, with other adding by one or more the fragrant volatile oil produced in peppermint, rhizoma atractylodis, Wrinkled Gianthyssop Herb, the folium eucalypti, can relieving emotional stress, anxiety and depression.These plants essential oil preparations and other present commercially available plant fragrance preparation all do not have the report that promotes psychosoma harmony degree effect aspect, majority is that the mood that can make the people is loosened, chilled out, heart rate is slack-off, the parasympathetic nerve excitability increases, being a kind of " psychosoma is loosened " state, is not the optimum regime of " the psychosoma harmony " of study, work, answering pressure challenge.
The preparation method of plant fragrance essential oil and perfume has steam distillation, organic solvent extraction, press for extracting juice mill method, absorption method, supercritical CO 2 extraction process, ultrasonic extraction method, microwave radiation to induce abstraction technique, microcapsule at present
-Aqueous two-phase extraction method, enzyme extraction method etc., these methods have the scope of application, advantage and deficiency (referring to " fragrance flavor and cosmetic " in October, 2008) separately.Because equipment is simple, easy to operate, distillation method is a most widely used method in the preparation of plant fragrance essential oil, and service temperature is higher, the time, length, lower boiling and water soluble ingredient lacked bigger shortcoming but distillation technique exists.That the supercritical CO 2 abstraction technique then is fit to is fat-soluble, high boiling point, thermo-sensitivity composition, now is widely used in the research with volatile component; But because of relating to high-pressure system, technological process and technical requirements height, cost of equipment has limited the widespread use of this method in the preparation of plant fragrance essential oil than costliness etc.Method for preparing plant fragrance preparation majority just extracts existing effective constituent in the starting material, there is no the activeconstituents of regulating psychology and physiological status and generates.
Microbial fermentation technology is widely used in fields such as traditional food, medicinal industry at present.When utilizing microbial fermentation vegetalitas Chinese medicinal materials, can make the cellulosic in the traditional Chinese medicine ingredients obtain degraded, many macromolecular components in the Chinese medicine material are decomposed into low molecular structure, promote the human absorptivity; Chinese medicine can form the new adjusting psychology that methods such as distillation, extraction can't obtain and/or the active substance of physiological status during the fermentation; And can surmount and extract limited this limitation of organic solvent, not contain advantages such as agricultural chemicals and heavy metal, the preparation security height that fermentation obtains.Patent documentation " technology of preparing fugui ostealgia compound by microorganism fermentation method " (publication number: CN101606991) introduced the concrete utilization example of microbial fermentation technology, but document and the patent report that utilizes fermentation technique to prepare the vegetalitas balm do not arranged at present as yet in Chinese medicine processing and preparation with " preparation method of the microbial fermentation preparation of the Radix Astragali " (publication number: CN 101664432).
Summary of the invention
The object of the present invention is to provide a kind of promote people body-centered body harmony degree (physiology and psychological harmonious level), plant fragrance preparation of relieving emotional stress, anxiety, depression and preparation method thereof.Plant fragrance preparation disclosed by the invention comprise by vegetable material cypress and Fructus Citri Sarcodactylis, Rosmarinus officinalis, the fragrant solution produced of one or more prescriptions in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber.
" monarch " is the fundamental principle of Chinese materia medica compound, the wherein main effect of monarch drug in a prescription performance, ministerial drug and the less important and booster action of adjuvant performance, these medicinal materials carry out compound according to certain ratio, can make the maximum effect of compound performance, give unique dual regulation simultaneously.We are by a large amount of experiments, has an alleviation anxiety from hundreds of, hypermnesis, improve in the scented plants of effects such as feelings will and screen, and carry out prescription according to " monarch " principle, detecting heart rate variability (HRV) index by HeartMath emWave PC system, to measure each prescription fermented liquid be substantially to promoting the effect of psychosoma harmony degree, having established with the cypress, be aided with Fructus Citri Sarcodactylis, Rosmarinus officinalis, serial scented plants prescriptions such as rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae.These prescriptions adopt microbial fermentation technology and prepared to become to have the natural aromatic agent of promote people body-centered body harmony degree, be used to take an entrance examination, compete, apply for, give a lecture, performance etc. has the occasion of pressure challenge, when relaxing unhealthy emotions such as anxiety, anxiety and depression, improve performance and job performance.
Technical scheme of the present invention is as follows:
But the plant fragrance preparation of promote people disclosed by the invention body-centered body harmony degree, be with cypress and be selected from Fructus Citri Sarcodactylis, Rosmarinus officinalis, any one or more than one vegetable material in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber is prepared from through microorganism fermentation process.
Preferably, described plant fragrance preparation with cypress and be selected from Fructus Citri Sarcodactylis, Rosmarinus officinalis, any in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber more than five kinds or five kinds vegetable material be prepared from through microorganism fermentation process.
Again preferably, the consumption that wherein is used to produce the vegetable material of perfume compound is a cypress 8
~10 weight parts; Except that cypress, add in addition Fructus Citri Sarcodactylis, Rosmarinus officinalis, in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber more than five kinds or five kinds, the consumption of above-mentioned vegetable material is respectively: Fructus Citri Sarcodactylis 4
~8 weight parts, Rosmarinus officinalis 4
~8 weight parts, rose 4
~8 weight parts, lavandula angustifolia 6
~10 weight parts, needle juniper 2
~4 weight parts, iris 2
~4 weight parts, Semen Myristicae 2
~4 weight parts, amber 1
~4 weight parts.
In the preferred embodiments of the present invention 3, plant fragrance preparation recipe proportioning is: cypress 6 weight parts, Rosmarinus officinalis 4 weight parts, rose 4 weight parts, Fructus Citri Sarcodactylis 3 weight parts, iris 2 weight parts, Semen Myristicae 2 weight parts, amber 1 weight part.
The present invention also provides a kind of microbial fermentation preparation method of vegetalitas balm, is vegetable material is cleaned, and chopping, mixes, and adds a certain proportion of dry yeast, 37 ℃ of ferment at constant temperature 1 year, and fermented liquid centrifuging and taking supernatant liquor obtains balm.Fermenting process can be taked any disclosed conventional microorganism fermentation process method in this area.
Plant fragrance preparation at promote people of the present invention body-centered body harmony degree is with cypress, with be equipped with Fructus Citri Sarcodactylis, Rosmarinus officinalis, any one or more than one vegetable material in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber, chopping, mixing, add a certain proportion of dry yeast in the vegetable material, 37 ℃ of ferment at constant temperature 1 year make balm with fermented liquid centrifuging and taking supernatant liquor after the filtration.Preferably, with cypress and be selected from Fructus Citri Sarcodactylis, Rosmarinus officinalis, any in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber more than five kinds or five kinds vegetable material be prepared from through microorganism fermentation process, the consumption of above-mentioned vegetable material is respectively: cypress 8
~10 weight parts, Fructus Citri Sarcodactylis 4
~8 weight parts, Rosmarinus officinalis 4
~8 weight parts, rose 4
~8 weight parts, lavandula angustifolia 6
~10 weight parts, needle juniper 2
~4 weight parts, iris 2
~4 weight parts, Semen Myristicae 2
~4 weight parts, amber 1
~4 weight parts.
Wherein, above-mentioned vegetable material cypress grinding particle size can be the 10-100 order;
Above-mentioned vegetable material and dry yeast weight part ratio are 200:1;
Above-mentioned fermented liquid is centrifugal can be under relative centrifugal force RCF=2000g condition, centrifugal 15 minutes.
Balm of the present invention comprises various suctions or external preparation, can be sprays, aerosol, make ointment, ointment, liniment or finish etc. after being coated with the nose agent or adding the conventional auxiliary material of cosmetics.
The invention has the beneficial effects as follows, plant fragrance preparation of the present invention is except having unhealthy emotions such as the mitigation anxiety that balm possessed, anxiety, depression such as frequently seen plants essential oil, since compound prescription-employing with cypress and be selected from Fructus Citri Sarcodactylis, Rosmarinus officinalis, any one or more than one vegetable material in the rose, lavandula angustifolia, needle juniper, iris, Semen Myristicae, amber; Effectively screening method-world-leading the stress management of the employing research institution-graduate emWave PC of U.S. HeartMath heart energy system through the heart rate variability metrics, detects various compound fermentation liquid and has the harmonious kilsyth basalt of best raising psychosoma now; And in fermentation process, form the new adjusting psychology and/or the active substance of physiological status, the fermented liquid that contains these active substances can promote user's psychosoma harmony degree, thereby can make the user in examination, application, speech, the contour pressure occasion of performance, when keeping perfect, stable, gentle psychosomatic state, the raising performance.The present invention also provides a kind of method that promotes product activity, effect and security for the preparation of plant fragrance agent in addition.
Experiment further specifies plant fragrance preparation effect of the present invention below:
Implement in No.1 Hospital of Jilin Univ. health control center in December, 2009.45 nurses of picked at random are randomized into plant fragrance preparation test group of the present invention, certain perfume control group, physiological saline blank group, every group of each 15 person of participating in the experiment.Detect the changing conditions that the experimenter uses the rate value sum of the camber harmony before and after 20 minutes with the emWave PC HRV heart rate variability test macro of U.S. HeartMath development; Found that the rate value of the average camber harmony before the physiological saline group is used is 32.2, then is 33.7 after the use, ascensional range not obvious (4.76%, p〉0.05); The rate value of the average camber harmony before the perfume group is used is 30.2, then is 30.9 after the use, ascensional range also not obvious (2.21%, p〉0.05); The rate value of the average camber harmony before plant fragrance preparation experimental group of the present invention is used is 27.4, is 37.2 after the use, and ascensional range is (35.77%, p<0.05) very obviously.
Gather in addition above three groups of experimenters and use salivas before and after 15 days continuously, measure its physiological stress mark-chromogranin (Chromogranin A, CgA) level, and carry out statistical study recording result difference before and after the experiment.It is 97.1 ng/mL that the average saliva CgA of physiological saline group level begins, and is 93.4 ng/mL after 15 days, fall not obvious (3.82%, p〉0.05).It is 71.1 ng/mL that the average saliva CgA of perfume group level begins, and is 67.3 ng/mL after 15 days, fall not obvious (5.31%, p〉0.05); The experiment of the average saliva CgA of plant fragrance preparation group of the present invention level begins to be 62.8ng/mL, and using after 15 days is 52.7 ng/mL, and fall is (15.98%, p<0.01) very obviously.
More than experiment prompting, plant fragrance preparation of the present invention can significantly promote the harmonious level value of user's camber, improve psychosoma harmony degree, effectively release slow pressure, thereby help unhealthy psychologies such as keeping tensions down, anxiety, depression, and improve performance.
Embodiment
Below in conjunction with embodiment technical characterictic of the present invention and technique effect are described further, but the scope of protection of present invention is not confined to the scope of embodiment statement.
Embodiment 1
Proportioning raw materials: cypress 4 kg, Fructus Citri Sarcodactylis 2kg.
By proportioning cypress, Fructus Citri Sarcodactylis are cleaned, chopping, drop in the container with the 30g dry yeast, add the 20L pure water, after stirring abundant mixing, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year, with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 2
Proportioning raw materials: cypress 4 kg, Fructus Citri Sarcodactylis 2kg, Rosmarinus officinalis 2kg, rose 2kg.
By proportioning with cypress, Fructus Citri Sarcodactylis, Rosmarinus officinalis, rose cleans, chopping, drop in the container with the 50g dry yeast, add the 30L pure water, after stirring abundant mixing, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year, with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 3
Proportioning raw materials: cypress 4 kg, Fructus Citri Sarcodactylis 2kg, Rosmarinus officinalis 2kg, rose 2kg, lavandula angustifolia 3kg, needle juniper 2kg, iris 2kg, Semen Myristicae 2kg, amber 1kg.
By proportioning Semen Myristicae, amber are cleaned, drying and grinding, 100 orders sieve, and cypress, Fructus Citri Sarcodactylis, Rosmarinus officinalis, rose, lavandula angustifolia, needle juniper, iris chopping drop in the container with the 100g dry yeast, add the 60L pure water, after stirring abundant mixing, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year, with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 4
Proportioning raw materials: cypress 5 kg, Fructus Citri Sarcodactylis 4kg, Rosmarinus officinalis 3kg, rose 2kg, lavandula angustifolia 2kg, needle juniper 4kg, iris 2kg, Semen Myristicae 3kg, amber 1kg.
By proportioning Semen Myristicae, amber are cleaned, drying and grinding, 100 orders sieve, and cypress, Fructus Citri Sarcodactylis, Rosmarinus officinalis, rose, lavandula angustifolia, needle juniper, iris clean, chopping, drop in the container with the 130g dry yeast, add the 80L pure water, stir abundant mixing after, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 5
Proportioning raw materials: cypress 6kg, Rosmarinus officinalis 4kg, rose 4kg, Fructus Citri Sarcodactylis 3kg, iris 2kg, Semen Myristicae 2kg, amber 1kg.
By proportioning Semen Myristicae, amber are cleaned, drying and grinding, 100 orders sieve, and cypress, Rosmarinus officinalis, rose, Fructus Citri Sarcodactylis, iris clean, chopping, drop in the container with the 110g dry yeast, add the 70L pure water, stir abundant mixing after, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 6
Proportioning raw materials: cypress 6kg, lavandula angustifolia 4kg, Fructus Citri Sarcodactylis 3kg, needle juniper 3kg, iris 2kg, Semen Myristicae 2kg.
By proportioning Semen Myristicae is cleaned, drying and grinding, 100 orders sieve, and cypress, lavandula angustifolia, Fructus Citri Sarcodactylis, needle juniper, iris are cleaned, chopping, drop in the container with the 100g dry yeast, add the 60L pure water, stir abundant mixing after, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 7
Proportioning raw materials: cypress 6kg, Fructus Citri Sarcodactylis 3kg, needle juniper 3kg, iris 2kg, Semen Myristicae 2kg, amber 1kg.
By proportioning Semen Myristicae, amber are cleaned, drying and grinding, 100 orders sieve, and cypress, Fructus Citri Sarcodactylis, needle juniper, iris are cleaned, chopping, drop in the container with the 85g dry yeast, add the 50L pure water, stir abundant mixing after, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
Embodiment 8
Proportioning raw materials: cypress 6kg, rose 4kg, Fructus Citri Sarcodactylis 3kg, needle juniper 3kg, iris 2kg, Semen Myristicae 2kg.
By proportioning Semen Myristicae is cleaned, drying and grinding, 100 orders sieve, and cypress, rose, Fructus Citri Sarcodactylis, needle juniper, iris are cleaned, chopping, drop in the container with the 100g dry yeast, add the 60L pure water, stir abundant mixing after, insert fermentor tank, 37 ℃ of ferment at constant temperature 1 year with filtrate under relative centrifugal force RCF=2000g condition centrifugal 15 minutes, get that supernatant is aseptic subpackaged to be sealed up for safekeeping after the filtration.
The balm that above embodiment produces is a liquid, but direct packaging becomes sprays, basting agent, is coated with the nose agent and directly uses; Also can add commercially available champignon instrument, ultrasonic atomizing device directly uses; Also can add the conventional auxiliary material of cosmetics and make ointment, ointment, liniment or finish etc.