CN101995454A - Detecting device and using method thereof - Google Patents
Detecting device and using method thereof Download PDFInfo
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- CN101995454A CN101995454A CN2009101021131A CN200910102113A CN101995454A CN 101995454 A CN101995454 A CN 101995454A CN 2009101021131 A CN2009101021131 A CN 2009101021131A CN 200910102113 A CN200910102113 A CN 200910102113A CN 101995454 A CN101995454 A CN 101995454A
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Abstract
The invention relates to a detecting device, which comprises a detecting cavity and an indicating element, wherein the detecting cavity accommodates a detecting element which analyzes whether a sample contains an analyzed object; and the indicating element displays whether the detection is activated. The invention also relates to a using method of the detecting device, which comprises the following steps of: collecting a liquid sample; observing the indicating element and judging whether the detection is activated; and detecting. The invention has the advantages that: the detecting device can effectively protect the position variation of a transfer cavity and is easy to operate when the detection is activated; besides, after the detection is activated, the detecting device can display a signal to facilitate detection timing and judgment.
Description
Technical field
The present invention relates to a kind of pick-up unit, especially a kind of pick-up unit that detects illegal drug.
Background technology
At present, it is more and more easier that general public obtains violated medicine, and the use of the medicine of therefore violating a ban is also more and more.For the safety that guarantees working environment and the fair competition of physical culture, the employee need detect in enterprise, unit and sports organization, athletic body fluid is for example urinated, and whether has used violated medicine to understand employee and sportsman.What therefore Humoral sample Detection and Collect device was used is more and more, and need be operated by the layman in common occasion.Use traditional liquid sample collection and detection device, exist amount of liquid can not be accurately quantitatively to produce, the requirement in the time of can not satisfying the accurate quantification of liquid sample or micromanipulation the influential situation of testing result.
U.S. Pat 6372515 discloses a sample collection pick-up unit, and this device comprises a test card of collecting the urine sample cup of urine sample and having many detector bars, and detector bar is used for detecting urine sample.During use, test card is inserted the urine sample cup, allow detector bar contact with urine sample, detection can be finished in a few minutes like this.After detection was finished, the urine sample in the urine sample cup was the material contamination in the detected reagent strip, can not finish the secondary affirmation checking that the professional carries out.
ZL 200420107950.6 discloses a body fluid sample pick-up unit, and by the piston hole of the end opening that glass body bottom has is set, and the through hole that communicates with the cup chamber and the through hole that communicates with slot carry out the transfer of liquid sample, realizes detection by quantitative.In the disclosed utility model of this piece of writing, comprise first through hole and second through hole, but causing the ring groove in the piston hole easily in the reagent operating process, this mode is detained bubble and sample, cause the error of detection by quantitative to cause that the result is inaccurate.
ZL 200720303101.1 discloses a kind of liquid sample collection and detection device, this pick-up unit comprises collecting chamber, test chamber and transfer chamber, transfer chamber links to each other with test chamber with collecting chamber respectively by at least two through holes, and wherein the opening two ends of at least one through hole are positioned at the extreme higher position of transfer chamber or the both sides of extreme lower position.This patent by the lead to the hole site that changes liquid sample detection device inside solve in common pick-up unit, exist because thereby the excessive bubble that produces of flow rate of liquid causes the mobile not enough problem of amount of blocking up and being used to detect sample of liquid sample.
Summary of the invention
The present invention relates to a kind of pick-up unit, comprise and hold the test chamber that whether contains the detecting element of analyte in the analyzing samples, and an indicator elment that shows whether detection is activated.This indicator elment on the one hand, shows mainly whether detecting element was used, and under the situation that liquid sample exists, indicator elment indication detecting element has been used, and illustrates to detect to be activated.In addition, if before detecting, with regard to obtaining the signal that detection that indicator elment sends is activated, pick-up unit then is described by maloperation, such pick-up unit and detecting element are considered as being used, and also are considered as simultaneously detecting being activated, and can not be used to detect.Preferably, pick-up unit also comprises and also comprises the transfer chamber of liquid sample being transferred to test chamber.More preferred, pick-up unit also comprises the collecting chamber that is used to collect liquid sample, and transfer chamber connects collecting chamber and test chamber.For this pick-up unit that has transfer chamber, especially rely on transfer chamber liquid sample is transferred to the pick-up unit of test chamber from collecting chamber, need realize the transfer of liquid sample by the change of transfer chamber position.In a specific embodiment, the position change of transfer chamber is realized by a push mechanism, wherein, if the liquid sample in the transfer chamber has been transferred in the test chamber, we can be by an indicator elment acquired information that shows that detection is activated, at this moment, liquid sample activates and the start detection reaction with the contact of the detectable bar in the test chamber.Preferably, this indicator elment is followed moving of transfer chamber and is moved, and this mode can move the position that must react transfer chamber more directly perceived, thereby whether the more clearly detection that shows is activated.More preferred, pick-up unit also comprises a watch window, is used to observe indicator elment, obtains to detect the signal that whether is activated.In addition, the invention still further relates to a push mechanism, this push mechanism can activate the liquid flow of transfer chamber to test chamber, and this push mechanism also comprises a barrier element that links together with push mechanism before detection is activated.This barrier element; can stop the unusual promotion of push mechanism before detection is activated; such as in the production assembling process; in transportation; collect in sample process and other processes the detected person,, cause in unusual promotion if there is not temporary transient " protection " effect of barrier element; whole detection device will be in can't duty, and this detects for quick diagnosis is disadvantageous.Preferred in addition, this barrier element that is connected as a single entity with push mechanism before detection is activated can peel off from push mechanism before activating detection.
The invention still further relates to the using method of pick-up unit 100: collect liquid sample; Observe indicator elment 8 and judge to detect and whether be activated; Detect.Preferably, pick-up unit 100 also comprises the transfer chamber 22 of liquid sample being transferred to test chamber 32, and indicator elment 8 is positioned at transfer chamber 22 and changes the position along with the position change of transfer chamber 22.Its using method comprises: collect liquid sample; Promote transfer chamber 22 and make liquid sample flow to test chamber 32 from transfer chamber 22, wherein indicator elment 8 moves along with moving of transfer chamber 22; Observe indicator elment 8 and judge that activation detects; Detect.
The invention has the beneficial effects as follows: can effectively must protect the position change of transfer chamber, and when detect activating, be very easy to operation, in addition, and can shows signal after detection is activated, be convenient to detect timing and judgement.
Description of drawings
Fig. 1 is the stereographic map of the present invention's one specific embodiment;
Fig. 2 is the front schematic view of the present invention's one specific embodiment;
Fig. 3 is the explosive decomposition figure of the present invention's one specific embodiment;
Fig. 4 is the view of the present invention's one specific embodiment before detection;
Fig. 5 for the present invention's one specific embodiment when detecting and the view after detecting.
Description of reference numerals: pick-up unit (urine cup) 100; Bowl cover 1; Cup body 2, rim of a cup 20, rim of a cup screw thread 201, collecting chamber 21, piston hole (transfer chamber) 22, piston 23, rubber band 24, piston hole opening 25, open ring groove 26, last through hole 27, lower through-hole 28, piston hole 29; Cup 3, thieving paper 31, test chamber 32, support bar 33, slot 34; O-ring seal 4; Test card (test card) 5, testing result viewing area 51, the detectable rule 52, plate 53, plate opening 54, adhesive sticker window 55, plate projection 56; Push mechanism 6 pushes away handle 60, and catch ring 61,63 is affectedly bashful place 62; Closed ring groove 7; Indicator elment 8.
Embodiment
Structure or these employed technical terms to pick-up unit is described further below.
Detect the expression chemical examination or test a kind of material or whether material exists, such as, but be not limited to this, the metabolin of chemical substance, organic compound, mineral compound, metabolism product, medicine or drug metabolite, organic organization or organic organization, nucleic acid, protein or polymkeric substance.In addition, detect the quantity of expression test substances or material.Furtherly, immune detection, chemical detection, enzyme detection etc. are also represented in chemical examination.
The sample of indication of the present invention refers to that those can be used for detecting, chemically examining or diagnose the material that whether has analyte of interest matter.Sample can be that for example, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise that solid sample and semi-solid samples are through anticipating the liquid solution that the back forms.The sample of collecting can be used for methods such as immune detection, chemical detection, enzyme detection and detect whether there is analyte.
Can analyze any analyte with apparatus and method of the present invention.The example of the analyte of the enough apparatus and method stable detection of the present invention of energy comprises (but not only comprising) human chorionic gonadotrophin (hCG), lutropin (LH), ovarian stimulation element (FSH), hepatitis C virus (HCV), hepatitis B (HBV), hepatitis B surface antigen, the medicine of AIDS virus and any abuse.Analyte can detect in any liquid or liquefied sample, urine for example, saliva, saliva, blood, blood plasma, perhaps serum.The example of other analyte also has the acid of flesh ammonia acid anhydride, cholerythrin, nitrite, protein (nonspecific), blood, leucocyte, blood sugar, heavy metal and toxin, the bacterium composition is (for example, special protein and the sugar of the bacterium of particular type, any other analyte of suitable lateral flow assay form can detect with this device.
Analyte can also be some haptens materials, and these haptens comprise drugs (as drug abuse)." drug abuse " (DOA) is meant that the non-medical destination uses medicine (playing the paralysis nerve usually).Abuse these medicines and can cause body ﹠ mind to suffer damage, produce dependence, habit-forming and/or dead.The example of drug abuse comprises cocaine; Amphetamine (for example, black beauty, white amphetamine tablet, dextroamphetamine, dexie, Beans); Crystal methamphetamine (crank, meth, crystal, speed); Barbiturate (as Valium, Roche Pharmaceuticals, Nutley, New Jersey); Sedative (paramedicines of promptly sleeping); Lysergic acid diethylamide (LSD); Inhibitor (downers, goofballs, barbs, blue devils, yellow jackets, methaqualone); The anti-antidepressant of tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline and doxepin); Hog (PCP); Tetrahydrocannabinol (THC, pot, dope, hash, weed, etc.); Opiate (being morphine, opium, codeine, heroin, the hydroxyl dihydrocodeinone); Anxiolytic and hypnotic sedative agent, anxiolytic is that a class is mainly used in anxiety reduction, nervous, frightened, set the mind at rest, have the medicine of hypnosis sedation concurrently, comprise Benzodiazepines (benzodiazepines, BZ), atypia BZ class, merge phenodiazine NB23C class, the tall and erect class of benzene nitrogen, the part class of BZ acceptor, open loop BZ class, diphenylmethane derivatives, the piperazine carboxylic acid salt, the piperidine carboxylic acid salt, Kui azoles quinoline ketone, thiazine and thiazole, other heterocyclic, imidazole type calmness/anodyne, propanediol derivative-carbamates, fatty compound, anthracene derivative etc.Use this device also can be used to detect and belong to medical usage but the detection of overdose easily, as tricyclic antidepressant (imipramine or analog) and Paracetamol etc.Can resolve into different small-molecule substances after these medicines are absorbed by the body, these small-molecule substances are present in the body fluid such as blood, urine, saliva, sweat or there is above-mentioned small-molecule substance in part body fluid.
Pick-up unit
The pick-up unit 100 that the present invention relates to comprises the test chamber 32 of holding the detecting element 5 that whether contains analyte in the analyzing samples.Pick-up unit 100 can be made by multiple difformity and different materials, for example the plastics of all size.
In a concrete embodiment, pick-up unit 100 also comprises an indicator elment 8 that shows whether detection is activated.This indicator elment 8 on the one hand, shows mainly whether detecting element 5 was used, and under the situation that liquid sample exists, indicator elment 8 indication detecting elements 5 have been used, and illustrate to detect to be activated.In addition on the one hand, if before detecting, just obtain the signal that detection that indicator elment 8 sends is activated, illustrate that then pick-up unit 100 is by maloperation, such pick-up unit 100 and detecting element 5 are considered as being used, and also are considered as simultaneously detecting being activated, and can not be used to detect.So detecting element 5 had been used or pick-up unit 100 was used, all be to be considered to detect be activated.The signal that detection is activated can be that indication element 8 is own, also can be the signal that indication element 8 and other materials react and form.This indicator elment 8 comprises the chemistry indication, such as the mode by Show Color.In one embodiment, can such as the reaction that utilizes potassium rhodanide and ferric ion, wine-colored color reaction appear by the reaction of chemical substance.Indicator elment also can comprise employing food coloring in a further embodiment.In another embodiment, described indicator elment 8 comprises the PH agent.On the indicating area, be written into the material that has the PH agent, such as the PH test paper, according to the pH value difference of liquid sample, the pH value of urine between 5-7, be positioned at the PH test paper contact sample on the indicating area after, soaked into into grass green by original yellow, change color takes place, and reaches indicative function.In addition, indication also comprises the physics indication, in one embodiment, described indicator elment 8, it can be a coloured material, this material to small part is covered by a basic opaque layer, when liquid exists, clear described coloured material can be observed thereby described opaque layer becomes transparent.In another embodiment, indicator elment 8 can be a colored adhesive sticker 8, and this adhesive sticker 8 is not easy in sight or hiding before detection, can more clearlyly get in sight after detection is activated.Preferably, pick-up unit 100 also comprises the transfer chamber 22 that is used to collect the collecting chamber 21 of liquid sample and liquid sample is transferred to test chamber 32 from collecting chamber 21.Indicator elment 8 can be positioned at arbitrary position of pick-up unit, as collecting chamber 21, transfer chamber 22 or test chamber 32.Wherein more preferred, because transfer chamber 22 is to detect the key that is activated, so indicator elment 8 can be positioned on the transfer chamber 22.In a specific embodiment, indicator elment 8 can be positioned on the transfer chamber 22, and changes the position along with the position change of transfer chamber 22.Specifically, after collecting liquid sample, liquid sample is present in collecting chamber 21 and the transfer chamber 22, at this moment, promote transfer chamber 22 and make liquid sample enter test chamber 32, in test chamber 32, exist detecting element 5, the sample absorption piece of detecting element 5 can detect with the liquid sample of test chamber 32, detects thereby cause.Such indicator elment 8 is set, if liquid sample has entered test chamber 32, also can judge that the detection in the test chamber 32 begins simultaneously rapidly, therefore, whether whether indicator elment 8, also indicated to detect to be activated when transfer chamber 22 flows to test chamber 32 at the indicating liquid sample.Preferable, transfer chamber 22 comprises the piston hole that has piston 23, piston 23 and piston hole have been formed some ring grooves.Wherein liquid sample can keep in the open ring groove 26 of transfer chamber 22 and shift, and indicator elment is arranged in closed ring groove 7.When the open ring groove 26 of transfer chamber 22 is pushed parts 6 when piston 23 depths promote, closed ring groove 7 also moves to the blind end of piston 23, and when open ring groove 26 and test chamber 32 were communicated with, indicator elment 8 sent and detects the signal that is activated.
More preferred, pick-up unit 100 also comprises watch window 54, is the window that is used to observe the indicator elment shows signal.This watch window 5421 can be positioned on the collecting chamber of pick-up unit, also can be positioned at transfer chamber 22 or test chamber 32 or other positions.Being positioned at the watch window 54 on the pick-up unit, can be transparent, can be clear see the signal that detects when being activated.Just can be used as watch window as transparent test chamber or transfer chamber itself.Preferably, watch window 54 can be a through hole on the test board 5 of test chamber.In general, pick-up unit 100 is plastic products, and test board 5 can be designed to plate 53 shapes of white, and a through hole 54 is set on plate 53, can see that by this through hole 54 indicator elment 8 that is arranged in transfer chamber sends the signal that detects beginning then.More preferred, before detection is not activated, indicator elment 8 is in primary importance, when push mechanism 6 promotes transfer chamber 22, make liquid sample in the transfer chamber 22 flow to test chamber 32 after, after promoting to finish, indicator elment 8 is positioned at the second place, this second place faces detection window 54, the through hole on the check-out console 54 just, and the operator of pick-up unit can be perfectly clear to such an extent that see indicator elment 8 itself and obtains to detect the signal that is activated by watch window 55 so.
In another embodiment, pick-up unit 100 can comprise a push mechanism 6.Be positioned at the detecting element 5 of test chamber 32, can not spontaneously carry out, need just can be activated under an action, push mechanism 6 can play the effect that the detection that makes test chamber 32 is activated.Promotion or other actions by push mechanism 6 make liquid sample enter test chamber 32, whether contain the reaction of the detecting element 5 of analyte in the excitation-detection liquid sample.Pick-up unit 100 can also comprise the collecting chamber 21 of collecting liquid sample, and the transfer chamber 22 that connects collecting chamber 21 and test chamber 32.The effect of push mechanism 6 is to make liquid sample flow to test chamber from transfer chamber, and activates detection reaction.The position of push mechanism 6, being used of preferred and transfer chamber 22.In a specific embodiment, push mechanism 6 can be positioned on the bowl cover 1, when needs promote, push mechanism 6 is taken out from bowl cover 1, and an end of transfer chamber 22 is pushed to an other end, the transfer of liquid sample in the realization transfer chamber 22.Preferably, push mechanism 6 links to each other with transfer chamber 22, directly promotes this parts 6 in use, handled easily.More preferred, this push mechanism 6 also comprises a barrier element 61,62,63.This barrier element 61,62,63rd is used to prevent the unusual promotion of push mechanism 6.Specifically, this barrier element 61,62,63 when not needing liquid to shift, stops the effect of push mechanism 6; When needs liquid shifts, barrier element 61,62,63 can be disengaged, thus push mechanism 6 begins to work.In a preferred embodiment, barrier element 61,62,63 and push mechanism 6 can be connected as a single entity.So-called being connected as a single entity, definite says, before detection is activated, barrier element 61,62,63 and push mechanism 6 link together, when needs activate detection, barrier element 61,62,63 can peel off from push mechanism 6, and push mechanism 6 just can be brought into play the effect that promotes transfer chamber 22 then.Transfer chamber 22 is a piston hole, comprises piston 23 in the piston hole 22 more in the preferred embodiment at one, barrier element 61,62, and 63 are wrapped in outside the piston 23, and push mechanism 6 cooperates with an end of piston 23.With barrier element 61,62,63 remove outside piston 23, and at this moment, push mechanism 6 can promote forward and not be subjected to barrier element 61,62,63 restriction, and the process of promotion can make liquid flow to test chamber 32 from transfer chamber 22, detects thereby activate.More preferred, barrier element 61,62,63 also comprise the projection that can be affectedly bashful 62, utilize this to be affectedly bashful place 62, can very conveniently barrier element 61,63 must be peeled off from push mechanism 6.
More than preferred, pick-up unit 100 can also comprise the collecting chamber 21 that is used to collect liquid sample, contains the test chamber 32 of test card 5 and liquid sample is transferred to the transfer chamber 22 of test chamber 32 from collecting chamber 21.
The cavity of collecting chamber 21 can adopt Any shape, such as cylindrical, and syringe-like shape, chimney, perhaps other can be used for any form of storaging liquid.Collecting chamber 21 can be by cup body 2, and rim of a cup 20 and bowl cover 1 are formed.Rim of a cup 20 and bowl cover 1 can guarantee that liquid holds and do not leak out by sealing in cup body 2.The seal form of rim of a cup 20 and bowl cover 1 can have multiple, such as rim of a cup 20 and bowl cover 1 screw thread 20 of working in coordination can be arranged, and reaches the effect of sealing by the mode of rotation.Better, can also in bowl cover 1, be provided with O-ring seal 4, the effect on the cup edge by O-ring seal 4 and rim of a cup 20 is played sealing function to device.
Test chamber 32 can comprise cup 3 and test card 5.The effect of cup 3 is to support whole detection device to be in equilibrium state.The bottom of cup 3 can also include absorbent material 31 and slot, and thieving paper 31 can absorb excess liquid in the slot 34, makes liquid that can not spill from cup 3 and contaminated environment.Can be inserted with detecting element 5 in the slot 34, be used for the tracer liquid sample and whether contain analyte.Also has support bar 33 in the slot 34, be used to support the plate projection 56 on the test card 5, make the test card 5 that has the tape test bar be suspended on the slot 34 of cup slightly, such benefit is, in the process of detectable bar 52 absorption liquid sample bodies, detectable bar 52 state of can always being kept upright can be because of crooked and not cause influencing the purpose of testing result.Detecting element 5 can be selected the test strip 52 of cross flow for use, also can be the plate 53 that has the plurality of detection reagent strip.Various detecting elements 5 can be combined and apply among the present invention together.A kind of form is to detect test paper, and another kind of form can be some reagent, is fixed on detection zone as the molecule that combines with the analyte specificity.Analyte in these reagent and the sample (if exist) reaction also is combined in this district with analyte, perhaps combines with the some reagent of actual zone, the mark substance that is used to show detection signal and reagent area or the mark zone that separates.These detectable bars or detectable all are the conventionally test means that those skilled in the art are familiar with.
The invention still further relates to the using method of pick-up unit 100: collect liquid sample; Observe indicator elment 8 and judge to detect and whether be activated; Detect.Preferably, pick-up unit 100 also comprises the transfer chamber 22 of liquid sample being transferred to test chamber 32, and indicator elment 8 is positioned at transfer chamber 22 and changes the position along with the position change of transfer chamber 22.Its using method comprises: collect liquid sample; Promote transfer chamber 22 and make liquid sample flow to test chamber 32 from transfer chamber 22, wherein indicator elment 8 moves along with moving of transfer chamber 22; Observe indicator elment 8 and judge to detect and whether be activated; Detect.Wherein preferred, pick-up unit 100 comprises that also an observation detects the watch window 54 that whether is activated.More preferred, the using method of pick-up unit 100 comprises: collect liquid sample; Promote transfer chamber 22 and make liquid sample flow to test chamber 32 from transfer chamber 22, wherein indicator elment 8 moves along with moving of transfer chamber 22; Observe the position of indicator elment 8 and judge that activation detects from watch window 54; Detect.
Below in conjunction with concrete accompanying drawing embodiments of the invention is described in detail.These specific embodiment only are limited the enumerating under spirit of the present invention, do not get rid of one of ordinary skill in the art prior art and the present invention in conjunction with and other specific embodiments of producing.
As Fig. 1, Fig. 2 and shown in Figure 3, this pick-up unit 100 comprises collecting chamber 21 and test chamber 32, and liquid in the collecting chamber 21 can be transferred to the piston hole (transfer chamber) 22 of test chamber 32.Collecting chamber 21 comprises glass body 2, and cup body 2 tops are provided with rim of a cup 20, and inside has a glass chamber; Rim of a cup 20 is provided with bowl cover 1, and the xsect of this bowl cover 1, rim of a cup 20 is circle, and bowl cover 1 is connected with rim of a cup 20 screw threads 201.Test chamber 32 bottoms are provided with cup 3, have slot 34 on the cup 3, two support bars 33 are arranged in the slot 34, be used to support the projection 56 on the plate, make the test card 5 that has the tape test bar be suspended on the slot 34 of cup slightly, such benefit is, in the process of detector bar absorption liquid sample body, detectable bar 52 state of can always being kept upright can be because of crooked and not cause influencing the purpose of testing result.Piston hole 22 communicates with the cup body by the last through hole 27 of its upper wall, and communicates with slot 34 by the lower through-hole 28 of lower wall, and cup 3 has a translot that communicates with slot 34 over against lower through-hole 28 places, and lower through-hole 28 communicates with slot 34 by this translot.Piston hole 22 built-in pistons 23, this piston 23 is in slipper seal with piston hole and cooperates, and these piston 23 front ends have open ring groove 26.Piston 23 is at the primary importance place, and open ring groove 26 communicates with the cup chamber by last through hole 27, but isolates with test board 5, becomes the cavity that can hold the liquid sample that stays in glass chamber, is with rubber band 24 on the piston 23.At second place place, open ring groove 26 is isolated with the cup chamber but is communicated with slot 34 by lower through-hole 28, and last through hole 27 and lower through-hole 28 can not communicate with open ring groove 26 simultaneously.Last through hole 27 is positioned at the extreme higher position 7 of piston hole, and opening one end is positioned at the intersection of piston hole 22 and cup body 2 inwalls, and the other end drops on the position that transfer chamber 22 is projected on glass body 2 inwalls.Lower through-hole 28 is positioned at the extreme lower position 8 of piston hole 22, and opening one end is positioned at the intersection of piston hole 22 and cup body 2 inwalls, and the other end drops on the position of piston hole 22 projections and test chamber 32 inwalls.Last through hole 27 and lower through-hole 28 are banded circular arc, and the opening two ends are 100 degree with the angle that the longitudinal axis by piston hole 22 forms.Last through hole 27 and lower through-hole 28 are not in same plane.At an end of piston 23, be provided with a push mechanism 6, comprise pushing away handle 60 and stopping ring 61,63 that wherein stopping ring has two, has one to be affectedly bashful place 62 in the middle of two obstruction rings.Stop between the ring 61,63 and stop ring 63 and the connection ratio that pushes away between the handle 60 is easier to be peeled off, the mode of peeling off is to encircle 63 and tear from pushing away handle 60 by being affectedly bashful place 62, will stopping.In addition, on the closed ring groove 7 of piston 23 and piston hole 22 and rubber band 24 compositions, wrapped up the adhesive sticker 8 of one deck green.On plate 53, have an aperture 54 in addition, corresponding, also leave a corresponding with it window 55 on the urine cup 100 outmost pressure sensitive membranes 51.Before detecting not generation, be to can't see green adhesive sticker 7 in window 55 and the aperture 54, after detection is activated, piston 23 is pushed handle 60 and has shifted the relevant position onto, and transfer has also taken place liquid sample, and is same, green adhesive sticker 8 has also taken place along with moving of piston 23 to move, thereby face the adhesive sticker 8 of visible green at above-mentioned aperture 54 and window 55, the express liquid sample enters test chamber 32 from transfer chamber 22, detects to be activated.
As shown in Figure 4 and Figure 5, piston 23 is when primary importance, and open ring groove 26 is aimed at and gone up through hole 27.During use, bowl cover 1 is taken off, with liquid sample for example urine sample add a cup chamber, liquid sample flows to the cavity that open ring groove 26 forms from last through hole 27.Utilize again and be affectedly bashful place 62 and will stop ring 61,63 and tear, push away handle 60 then piston 23 is pushed piston hole 22 depths, make open ring groove 26 aligning lower through-holes 28 from piston 23.At this moment, liquid sample flows into from lower through-hole 28 on the translot of cups 3, is flowing into slot 34 from translot, contact with test-strips 52 on being inserted in slot 34, activates detection.When open ring groove 26 is aimed at lower through-hole 28, closed ring groove 7 respective aligned the aperture 54 on the plate 53, in the aperture 54 of the window 55 of the panel of urine cup and test board, can clearly must see green adhesive sticker signal, show to detect and activate, testing result is shown.When needing further to detect, the liquid sample in the cup chamber can be delivered to the laboratory and further detect, confirm testing result by the professional.
Claims (21)
1. a pick-up unit comprises and holds the test chamber that whether contains the detecting element of analyte in the analyzing samples, it is characterized in that, described pick-up unit also comprises an indicator elment that shows whether detection is activated.
2. pick-up unit as claimed in claim 1 is characterized in that described pick-up unit also comprises the transfer chamber of liquid sample being transferred to test chamber, and described indicator elment is positioned at transfer chamber and changes the position along with the position change of transfer chamber.
3. pick-up unit as claimed in claim 2 is characterized in that described transfer chamber comprises the piston hole that has piston, and described piston and piston hole are formed open ring groove that shifts for liquid and the closed ring groove of settling indicator elment.
4. pick-up unit as claimed in claim 1 is characterized in that, described pick-up unit comprises that also an observation detects the watch window that whether is activated.
5. pick-up unit as claimed in claim 4 is characterized in that described indicator elment can not be observed at watch window before detection is activated, can be observed at watch window after detection is activated.
6. as the described pick-up unit of one of claim 1 to 5, it is characterized in that described indicator elment comprises colored adhesive sticker.
7. as the described pick-up unit of one of claim 1 to 5, it is characterized in that described test chamber comprises test board, described test board comprises a through hole, can see indicator elment by this through hole after detection is activated.
8. pick-up unit as claimed in claim 2 is characterized in that, described pick-up unit also comprises a push mechanism that makes liquid sample flow to test chamber from transfer chamber; Whether described indicator elment moves by the position of indication transfer chamber indicates detection to be activated.
9. pick-up unit as claimed in claim 8 is characterized in that described push mechanism also comprises the barrier element that is connected as a single entity with push mechanism.
10. pick-up unit as claimed in claim 8, it is characterized in that, described transfer chamber is to comprise the piston hole that has piston, described barrier element covers the outside of piston, described push mechanism is positioned at an end of piston hole, when detection was not activated, barrier element and push mechanism were connected as a single entity; When detection was activated, barrier element separated with push mechanism.
11. pick-up unit as claimed in claim 10 is characterized in that, push mechanism is irreversible activation for the liquid flow activation of pick-up unit.
12. pick-up unit as claimed in claim 1 is characterized in that, the support component that described test chamber is also erected detecting element.
13. a method of using pick-up unit, pick-up unit comprise test chamber and indicator elment that shows whether detection is activated that holds the detecting element that whether contains analyte in the analyzing samples, it is characterized in that,
Collect liquid sample;
Observe indicator elment and judge to detect and whether be activated;
Detect.
14. method as claimed in claim 13 is characterized in that, it is characterized in that, described pick-up unit also comprises the transfer chamber of liquid sample being transferred to test chamber, and described indicator elment is positioned at transfer chamber and changes the position along with the position change of transfer chamber.
15. method as claimed in claim 14 is characterized in that,
Collect liquid sample;
Promote transfer chamber and make liquid sample flow to test chamber from transfer chamber, wherein indicator elment moves along with moving of transfer chamber;
Observe indicator elment and judge to detect and whether be activated;
Detect.
16. method as claimed in claim 14 is characterized in that, described transfer chamber comprises the piston hole that has piston, and described piston and piston hole are formed open ring groove that shifts for liquid and the closed ring groove of settling indicator elment.
17. method as claimed in claim 13 is characterized in that, described pick-up unit comprises that also an observation detects the watch window that whether is activated.
18. method as claimed in claim 17 is characterized in that,
Collect liquid sample;
Promote transfer chamber and make liquid sample flow to test chamber from transfer chamber, wherein indicator elment moves along with moving of transfer chamber;
Observe the position of indicator elment and judge whether detection is activated from watch window; Detect.
19. method as claimed in claim 17 is characterized in that, described indicator elment can not be observed at watch window before detection is activated, and can be observed at watch window after detection is activated.
20., it is characterized in that described indicator elment comprises colored adhesive sticker as the described method of one of claim 13 to 19.
21., it is characterized in that described test chamber comprises test board as the described method of one of claim 13 to 19, described test board comprises a through hole, can see indicator elment by this through hole after detecting activation.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910102113.1A CN101995454B (en) | 2009-08-13 | 2009-08-13 | Detecting device and using method thereof |
| CN201410257435.4A CN104122385B (en) | 2009-08-13 | 2009-08-13 | A kind of detection device and using method thereof |
| EP10807856.9A EP2464965B1 (en) | 2009-08-13 | 2010-08-13 | Detection device and method of using the same |
| US13/389,433 US10107720B2 (en) | 2009-08-13 | 2010-08-13 | Detection device and method of using the same |
| PCT/CN2010/001227 WO2011017911A1 (en) | 2009-08-13 | 2010-08-13 | Detection device and method of using the same |
| EP19171432.8A EP3540405A1 (en) | 2009-08-13 | 2010-08-13 | Detection device and method of using the same |
| US16/166,714 US20190154549A1 (en) | 2009-08-13 | 2018-10-22 | Detection device and method of using the same |
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| CN105842434A (en) * | 2016-03-16 | 2016-08-10 | 杭州安旭科技有限公司 | Sample collection and detection apparatus |
| CN110174508A (en) * | 2019-06-12 | 2019-08-27 | 成都恩普生医疗科技有限公司 | A kind of multi-functional urine cup |
| WO2020048097A1 (en) * | 2018-09-09 | 2020-03-12 | 王水娟 | Pipetting indicating component and liquid detection device |
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