Summary of the invention
For medicament residue problem and the present situation of still not having special at all kinds of disease prevention and cure feed addictives of milk cow perinatal period that overcomes the existing conventional feed addictive, the invention provides a kind of compound Chinese herbal medicine additive, this compound Chinese herbal medicine additive can not only reduce the incidence of perinatal period and postpartum milk secretion peak period cow disease, improve the milk cow health situation, improve milk cow production performance, improve the reproductive performance of milk cow in postpartum.And this compound Chinese herbal medicine additive is pure natural, green, and to livestock and poultry animal, human without any side effects with environment, use for a long time can not developed immunity to drugs.
Technical scheme feature provided by the invention is: according to cow in perinatal period physiological stage characteristics, prepare two kinds of compound Chinese herbal medicine additive stage by stage:
The material composition of antenatal Chinese herbal formula A and weight portion ratio: the Radix Astragali 15, Radix Angelicae Sinensis 15, Divine Comedy 25, hawthorn 20, betel nut 15, felwort 30, radix bupleuri 20, cape jasmine 20, rhizoma alismatis 20, akebi 15, oriental wormwood 20, sweet wormwood 25, the dried rhizome of rehmannia 15, Radix Glycyrrhizae 10;
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations A fed from antenatal 14 days calving same day always;
Postpartum Chinese herbal formula B: Radix Angelicae Sinensis 15, the root of herbaceous peony 15, Ligusticum wallichii 15, safflower 15, peach kernel 20, radix bupleuri 20, felwort 30, cape jasmine 20, the root of large-flowered skullcap 15, rhizoma alismatis 15, akebi 15, rhizoma atractylodis 20, Divine Comedy 20, hawthorn 15, Radix Glycyrrhizae 10, motherwort 15.
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations B fed after the calving 14 days from calving the same day.
Advantage of the present invention is: this compound Chinese herbal medicine additive can not only strengthen the milk cow immunity in postpartum, reduce the incidence of perinatal period and postpartum milk secretion peak period cow disease, improve the milk cow health situation, improve milk cow production performance, improve the reproductive performance of milk cow in postpartum; And this compound Chinese herbal medicine additive is pure natural, green, and to livestock and poultry animal, human without any side effects with environment, use for a long time can not developed immunity to drugs.
The specific embodiment
According to cow in perinatal period physiological stage characteristics, prepare two kinds of compound Chinese herbal medicine additive stage by stage, prepare two kinds of compound Chinese herbal medicine additive stage by stage:
The material composition of antenatal Chinese herbal formula A and weight portion ratio: the Radix Astragali 15, Radix Angelicae Sinensis 15, Divine Comedy 25, hawthorn 20, betel nut 15, felwort 30, radix bupleuri 20, cape jasmine 20, rhizoma alismatis 20, akebi 15, oriental wormwood 20, sweet wormwood 25, the dried rhizome of rehmannia 15, Radix Glycyrrhizae 10;
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations A fed from antenatal 14 days calving same day always;
Postpartum Chinese herbal formula B material composition and weight portion ratio: Radix Angelicae Sinensis 15, the root of herbaceous peony 15, Ligusticum wallichii 15, safflower 15, peach kernel 20, radix bupleuri 20, felwort 30, cape jasmine 20, the root of large-flowered skullcap 15, rhizoma alismatis 15, akebi 15, rhizoma atractylodis 20, Divine Comedy 20, hawthorn 15, Radix Glycyrrhizae 10, motherwort 15.
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations B fed after the calving 14 days from calving the same day.
Compound Chinese herbal medicine additive provided by the invention is through following experiment:
Experiment 1:
Choose 30 of the pre-perinatal milk cows of lactating cow, be divided into 2 groups, every group 15 cow head.One group of said herbal medicine preparation of feeding respectively antenatal 14 days and 14 days postpartum, another is organized as blank.
Experimental result shows:
1. adding Chinese herb feed additive in the daily ration can improve milk cow lipid metabolism perinatal period function, reduce the pathogenesis of fatty liver rate.The content of free fatty (NEFA) in serum, the NEFA content before antenatal i.e. test in the serum, difference not remarkable (P>0.05) between test group and the control group.NEFA content in each in the postpartum test group cow's serum all is lower than the NEFA content in the control group cow's serum in period, different group differences in each period all extremely significantly (P<0.01).The content of triglycerides (TG) in serum, the TG content before antenatal i.e. test in the serum, difference not remarkable (P>0.05) between test group and the control group.TG content in one week of postpartum in the test group cow's serum is lower than the TG content in the control group cow's serum, significant difference (P<0.05).TG content after one week of postpartum in the test group cow's serum is lower than the TG content in the control group cow's serum, significant difference (P<0.05).TG content after two weeks of postpartum in the test group cow's serum is lower than the TG content in the control group cow's serum, and difference is (P<0.01) extremely significantly.The fatty liver test group of always falling ill is lower than control group, and the average attack rate of test group fatty liver is 23%, and the average attack rate of control group fatty liver is 48%.
2. the content of immunoglobulin (Ig) (IgG) in the serum, test group is compared with control group, the content of immunoglobulin (Ig) (IgG) in serum, the IgG content before antenatal i.e. test in the serum, difference not remarkable (P>0.05) between test group and the control group.IgG content in each in the postpartum test group cow's serum all is lower than the IgG content in the control group cow's serum in period, different group differences in each period all extremely significantly (P<0.01).
3. spontaneous estrus rate in 60 days postpartum aspect reproductive performance, test group is compared with control group, the spontaneous estrus rate is 53.33% in the test group 60 days, in the control group in 60 days the spontaneous estrus rate be 30.76%, the spontaneous estrus rate exceeds control group 22.57% in the test group 60 days.
4. aspect production performance, the test group output of milk is compared with the control group output of milk, and the test group output of milk is higher than control group, and in the average output of milk of 10-210 lactation day, test group is than the high 3.147kg of control group.The test group milk composition is compared with the control group milk composition, and the test group lactose is higher than the control group lactose content, and difference is (P<0.01) extremely significantly; Test group butterfat is higher than the control group dairy fat content, significant difference (P<0.05); The test group lactoprotein is higher than the control group content of milk protein, and difference is (P<0.01) extremely significantly.
Experiment 2:
Select latter half of gestation (antenatal 15d-20d) holstein cow of 48 health, body condition, parity, the output of milk close (P〉0.05) for use, the research influence of Chinese herb feed additive of feeding perinatal period to milk cow health and production performance.The antenatal compound Chinese herbal medicine additive A and the compound Chinese herbal medicine additive B that feeds postpartum of feeding.Test Niu Suiji is divided into 1,2,3 and 4 group (control group) of test.Test 1 group: add Chinese herb feed additive A at the antenatal basal diet of feeding, the basal diet of feeding postpartum adds Chinese herb feed additive B; Test 2 groups: only add Chinese herb feed additive A antenatal feeding in the basal diet; Test 3 groups: only add Chinese herb feed additive B in hello the basal diet in postpartum; Test 4 groups (control groups): all only feed basal diet antenatal and postpartum, do not add Chinese herb feed additive A and B.Chinese herb feed additive is by the ox of 300g/ head/be blended into day 1,2,3 groups of feeding experiments in the TRM.Test is carried out under identical feeding and management condition.Then, antenatal 14d and postpartum 7d, 14d and 21d gather the blood samples of 4 group oxen, carry out the physiochemical indice analysis; Gather the milk sample to the milk composition analysis and to the monitoring of milk cow health in postpartum and reproductive performance.Be intended to study which kind of Chinese herb feed additive action effect the best of feeding to health, the fatty liver of milk cow perinatal period, the performance of giving milk, immunologic function, reproductive performance etc.
Experimental result shows:
(1) in the cow in perinatal period daily ration, adds Chinese herb feed additive A and B can improve the health of milk cow perinatal period, strengthen the lipid metabolism function, reduce pathogenesis of fatty liver rate (test 1,2,3 group respectively hang down 48%, 48%, 36% than 4 groups (control groups)).
(2) adding Chinese herb feed additive A and B in the cow in perinatal period daily ration can increase the content of immunoglobulin (Ig) (IgG) in the milk cow serum in postpartum and strengthen the milk cow immunity and the premunition in postpartum, reduces the sick incidence of disease such as mammitis, hysteritis.
(3) in the cow in perinatal period daily ration, add Chinese herb feed additive A, B and can improve the cow reproduction performance.Each organizes the spontaneous estrus fate and the rate of oestrusing: test 1,2,3,4 group and be respectively 38d, 44d, 40d, 47d and 66.7%, 55.6%, 66.7%, 33.3%.
(4) interpolation Chinese herb feed additive A and B can improve the cow producing milk performance in the cow in perinatal period daily ration, and 1,2,3 group of average daily output of milk of 1-70d test increases 2.77kg/ head, 0.93 kg/ head, 1.48 kg/ heads than 4 groups (control group) respectively; And it is not obvious to the milk composition influence.
(5) perinatal period, milk cow was not only in antenatal Chinese herb feed additive A but also the mode best results of Chinese herb feed additive B of feeding in postpartum of feeding.
Experiment conclusion:
Perinatal period this Chinese herbal and crude drugs preparations of feeding can improve milk cow lipid metabolism perinatal period function, improve milk cow production performance, improve reproductive performance and reduce the pathogenesis of fatty liver rate, strengthen the milk cow immunity in postpartum.