CN101971933A - Disease-resistant health-care compound Chinese herbal medicinal feed additive for dairy cattle in perinatal period and feeding method - Google Patents

Disease-resistant health-care compound Chinese herbal medicinal feed additive for dairy cattle in perinatal period and feeding method Download PDF

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Publication number
CN101971933A
CN101971933A CN2010105403551A CN201010540355A CN101971933A CN 101971933 A CN101971933 A CN 101971933A CN 2010105403551 A CN2010105403551 A CN 2010105403551A CN 201010540355 A CN201010540355 A CN 201010540355A CN 101971933 A CN101971933 A CN 101971933A
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chinese herbal
compound chinese
postpartum
herbal medicinal
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CN101971933B (en
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郗伟斌
张永根
李胜利
杜绍范
王月
夏科
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Shenyang Grass Biological Technology Development Co ltd
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Shenyang Agricultural University
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Abstract

The invention relates to a disease-resistant health care compound Chinese herbal medicinal feed additive for dairy cattle in a perinatal period, which can prevent fatty liver for dairy cattle in the perinatal/postpartum period from happening, improves the reproductive performance of dairy cattle in the perinatal/postpartum period, and is characterized in that based on the physiological stage characteristics of the dairy cattle in the perinatal period, two compound Chinese herbal medicinal additives (an antenatal compound Chinese herbal medicinal preparation A and a postpartum compound Chinese herbal medicinal preparation B) are prepared by stages, wherein the antenatal compound Chinese herbal medicinal preparation A comprises the following raw material components in parts by weight: 15 parts of radix astragali, 15 parts of Angelica sinensis, 25 parts of medicated leaven, 20 parts of hawthorn, 15 parts of areca nut, 30 parts of felwort, 20 parts of radix bupleuri, 20 parts of fructus gardeniae, 20 parts of rhizoma alismatis, 15 parts of akebiaquinata, 20 parts of capillary Artemisia, 25 parts of Artemisia apiacea, 15 parts of rehmanniae praeparatum and 10 parts of liquorice; and the postpartum compound Chinese herbal medicinal preparation B comprises the following raw material components in parts by weight: 15 parts of angelica sinensis, 15 parts of white paeony root, 15 parts of ligusticum wallichii, 15 parts of safflower, 20 parts of peach seed, 20 parts of radix bupleuri, 30 parts of felwort, 20 parts of fructus gardeniae, 15 parts of scutellaria, 15 parts of rhizoma alismatis, 15 parts of akebiaquinata, 20 parts of rhizoma atractylodis, 20 parts of medicated leaven, 15 parts of hawthorn, 10 parts of liquorice and 15 parts of leonurus. The feed additive is stirred into a daily ration or grain feed in three steps, evenly mixed and fed to the cattle, wherein each cow needs 300g every day.

Description

Perinatal period milk cow disease-resistant health care compound Chinese herb feed addictive and feeding method
Technical field
The present invention relates to a kind of perinatal period of milk cow Chinese herbal feed additive, especially can prevent and treat perinatal period and postpartum milk cow fatty liver generation and improve the compound Chinese herbal medicine additive of reproductive performance.
Background technology
At present, in the milk cattle cultivating industry, on the one hand, use all feeds additive to improve health status, adjusting feed intake, raising nutriment and capacity usage ratio, raising production and the reproductive performance of milk cow in a large number.Feed addictive become milk cow growth, breed and indispensable important composition composition such as prevention from suffering from the diseases, and brought huge economic benefit for contemporary dairy.But people cause medicament residue in order to improve culturing economic benefit abuse feed addictive and excess drug, severe contamination livestock products, endangered the healthy of people.On the other hand, the incidence of disease of cow in perinatal period disease becomes cow death to have 70%-80% to occur in this period still up to 43%, so most important in perinatal period milk cow health care prevention of disease and the stable high yield of assurance milk cow.
Summary of the invention
For medicament residue problem and the present situation of still not having special at all kinds of disease prevention and cure feed addictives of milk cow perinatal period that overcomes the existing conventional feed addictive, the invention provides a kind of compound Chinese herbal medicine additive, this compound Chinese herbal medicine additive can not only reduce the incidence of perinatal period and postpartum milk secretion peak period cow disease, improve the milk cow health situation, improve milk cow production performance, improve the reproductive performance of milk cow in postpartum.And this compound Chinese herbal medicine additive is pure natural, green, and to livestock and poultry animal, human without any side effects with environment, use for a long time can not developed immunity to drugs.
Technical scheme feature provided by the invention is: according to cow in perinatal period physiological stage characteristics, prepare two kinds of compound Chinese herbal medicine additive stage by stage:
The material composition of antenatal Chinese herbal formula A and weight portion ratio: the Radix Astragali 15, Radix Angelicae Sinensis 15, Divine Comedy 25, hawthorn 20, betel nut 15, felwort 30, radix bupleuri 20, cape jasmine 20, rhizoma alismatis 20, akebi 15, oriental wormwood 20, sweet wormwood 25, the dried rhizome of rehmannia 15, Radix Glycyrrhizae 10;
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations A fed from antenatal 14 days calving same day always;
Postpartum Chinese herbal formula B: Radix Angelicae Sinensis 15, the root of herbaceous peony 15, Ligusticum wallichii 15, safflower 15, peach kernel 20, radix bupleuri 20, felwort 30, cape jasmine 20, the root of large-flowered skullcap 15, rhizoma alismatis 15, akebi 15, rhizoma atractylodis 20, Divine Comedy 20, hawthorn 15, Radix Glycyrrhizae 10, motherwort 15.
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations B fed after the calving 14 days from calving the same day.
Advantage of the present invention is: this compound Chinese herbal medicine additive can not only strengthen the milk cow immunity in postpartum, reduce the incidence of perinatal period and postpartum milk secretion peak period cow disease, improve the milk cow health situation, improve milk cow production performance, improve the reproductive performance of milk cow in postpartum; And this compound Chinese herbal medicine additive is pure natural, green, and to livestock and poultry animal, human without any side effects with environment, use for a long time can not developed immunity to drugs.
The specific embodiment
According to cow in perinatal period physiological stage characteristics, prepare two kinds of compound Chinese herbal medicine additive stage by stage, prepare two kinds of compound Chinese herbal medicine additive stage by stage:
The material composition of antenatal Chinese herbal formula A and weight portion ratio: the Radix Astragali 15, Radix Angelicae Sinensis 15, Divine Comedy 25, hawthorn 20, betel nut 15, felwort 30, radix bupleuri 20, cape jasmine 20, rhizoma alismatis 20, akebi 15, oriental wormwood 20, sweet wormwood 25, the dried rhizome of rehmannia 15, Radix Glycyrrhizae 10;
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations A fed from antenatal 14 days calving same day always;
Postpartum Chinese herbal formula B material composition and weight portion ratio: Radix Angelicae Sinensis 15, the root of herbaceous peony 15, Ligusticum wallichii 15, safflower 15, peach kernel 20, radix bupleuri 20, felwort 30, cape jasmine 20, the root of large-flowered skullcap 15, rhizoma alismatis 15, akebi 15, rhizoma atractylodis 20, Divine Comedy 20, hawthorn 15, Radix Glycyrrhizae 10, motherwort 15.
Said herbal medicine is dried, weighed by weight proportion.Pulverize the back to crossing the 40-60 mesh sieve, mix.Every interpolation every day 300g divides to admix in daily ration or the fine fodder for three times and feeds behind the mixing.This Chinese herbal and crude drugs preparations B fed after the calving 14 days from calving the same day.
Compound Chinese herbal medicine additive provided by the invention is through following experiment:
Experiment 1:
Choose 30 of the pre-perinatal milk cows of lactating cow, be divided into 2 groups, every group 15 cow head.One group of said herbal medicine preparation of feeding respectively antenatal 14 days and 14 days postpartum, another is organized as blank.
Experimental result shows:
1. adding Chinese herb feed additive in the daily ration can improve milk cow lipid metabolism perinatal period function, reduce the pathogenesis of fatty liver rate.The content of free fatty (NEFA) in serum, the NEFA content before antenatal i.e. test in the serum, difference not remarkable (P>0.05) between test group and the control group.NEFA content in each in the postpartum test group cow's serum all is lower than the NEFA content in the control group cow's serum in period, different group differences in each period all extremely significantly (P<0.01).The content of triglycerides (TG) in serum, the TG content before antenatal i.e. test in the serum, difference not remarkable (P>0.05) between test group and the control group.TG content in one week of postpartum in the test group cow's serum is lower than the TG content in the control group cow's serum, significant difference (P<0.05).TG content after one week of postpartum in the test group cow's serum is lower than the TG content in the control group cow's serum, significant difference (P<0.05).TG content after two weeks of postpartum in the test group cow's serum is lower than the TG content in the control group cow's serum, and difference is (P<0.01) extremely significantly.The fatty liver test group of always falling ill is lower than control group, and the average attack rate of test group fatty liver is 23%, and the average attack rate of control group fatty liver is 48%.
2. the content of immunoglobulin (Ig) (IgG) in the serum, test group is compared with control group, the content of immunoglobulin (Ig) (IgG) in serum, the IgG content before antenatal i.e. test in the serum, difference not remarkable (P>0.05) between test group and the control group.IgG content in each in the postpartum test group cow's serum all is lower than the IgG content in the control group cow's serum in period, different group differences in each period all extremely significantly (P<0.01).
3. spontaneous estrus rate in 60 days postpartum aspect reproductive performance, test group is compared with control group, the spontaneous estrus rate is 53.33% in the test group 60 days, in the control group in 60 days the spontaneous estrus rate be 30.76%, the spontaneous estrus rate exceeds control group 22.57% in the test group 60 days.
4. aspect production performance, the test group output of milk is compared with the control group output of milk, and the test group output of milk is higher than control group, and in the average output of milk of 10-210 lactation day, test group is than the high 3.147kg of control group.The test group milk composition is compared with the control group milk composition, and the test group lactose is higher than the control group lactose content, and difference is (P<0.01) extremely significantly; Test group butterfat is higher than the control group dairy fat content, significant difference (P<0.05); The test group lactoprotein is higher than the control group content of milk protein, and difference is (P<0.01) extremely significantly.
Experiment 2:
Select latter half of gestation (antenatal 15d-20d) holstein cow of 48 health, body condition, parity, the output of milk close (P〉0.05) for use, the research influence of Chinese herb feed additive of feeding perinatal period to milk cow health and production performance.The antenatal compound Chinese herbal medicine additive A and the compound Chinese herbal medicine additive B that feeds postpartum of feeding.Test Niu Suiji is divided into 1,2,3 and 4 group (control group) of test.Test 1 group: add Chinese herb feed additive A at the antenatal basal diet of feeding, the basal diet of feeding postpartum adds Chinese herb feed additive B; Test 2 groups: only add Chinese herb feed additive A antenatal feeding in the basal diet; Test 3 groups: only add Chinese herb feed additive B in hello the basal diet in postpartum; Test 4 groups (control groups): all only feed basal diet antenatal and postpartum, do not add Chinese herb feed additive A and B.Chinese herb feed additive is by the ox of 300g/ head/be blended into day 1,2,3 groups of feeding experiments in the TRM.Test is carried out under identical feeding and management condition.Then, antenatal 14d and postpartum 7d, 14d and 21d gather the blood samples of 4 group oxen, carry out the physiochemical indice analysis; Gather the milk sample to the milk composition analysis and to the monitoring of milk cow health in postpartum and reproductive performance.Be intended to study which kind of Chinese herb feed additive action effect the best of feeding to health, the fatty liver of milk cow perinatal period, the performance of giving milk, immunologic function, reproductive performance etc.
Experimental result shows:
(1) in the cow in perinatal period daily ration, adds Chinese herb feed additive A and B can improve the health of milk cow perinatal period, strengthen the lipid metabolism function, reduce pathogenesis of fatty liver rate (test 1,2,3 group respectively hang down 48%, 48%, 36% than 4 groups (control groups)).
(2) adding Chinese herb feed additive A and B in the cow in perinatal period daily ration can increase the content of immunoglobulin (Ig) (IgG) in the milk cow serum in postpartum and strengthen the milk cow immunity and the premunition in postpartum, reduces the sick incidence of disease such as mammitis, hysteritis.
(3) in the cow in perinatal period daily ration, add Chinese herb feed additive A, B and can improve the cow reproduction performance.Each organizes the spontaneous estrus fate and the rate of oestrusing: test 1,2,3,4 group and be respectively 38d, 44d, 40d, 47d and 66.7%, 55.6%, 66.7%, 33.3%.
(4) interpolation Chinese herb feed additive A and B can improve the cow producing milk performance in the cow in perinatal period daily ration, and 1,2,3 group of average daily output of milk of 1-70d test increases 2.77kg/ head, 0.93 kg/ head, 1.48 kg/ heads than 4 groups (control group) respectively; And it is not obvious to the milk composition influence.
(5) perinatal period, milk cow was not only in antenatal Chinese herb feed additive A but also the mode best results of Chinese herb feed additive B of feeding in postpartum of feeding.
Experiment conclusion:
Perinatal period this Chinese herbal and crude drugs preparations of feeding can improve milk cow lipid metabolism perinatal period function, improve milk cow production performance, improve reproductive performance and reduce the pathogenesis of fatty liver rate, strengthen the milk cow immunity in postpartum.

Claims (2)

1. the disease-resistant health care compound Chinese herb of milk cow perinatal period feed addictive is characterized in that:
The material composition of antenatal Chinese herbal formula A and weight portion ratio: the Radix Astragali 15, Radix Angelicae Sinensis 15, Divine Comedy 25, hawthorn 20, betel nut 15, felwort 30, radix bupleuri 20, cape jasmine 20, rhizoma alismatis 20, akebi 15, oriental wormwood 20, sweet wormwood 25, the dried rhizome of rehmannia 15, Radix Glycyrrhizae 10;
Postpartum Chinese herbal formula B material composition and weight portion ratio:: Radix Angelicae Sinensis 15, the root of herbaceous peony 15, Ligusticum wallichii 15, safflower 15, peach kernel 20, radix bupleuri 20, felwort 30, cape jasmine 20, the root of large-flowered skullcap 15, rhizoma alismatis 15, akebi 15, rhizoma atractylodis 20, Divine Comedy 20, hawthorn 15, Radix Glycyrrhizae 10, motherwort 15.
2. feeding method of the disease-resistant health care compound Chinese herb of milk cow perinatal period feed addictive according to claim 1 is characterized in that:
Every of antenatal Chinese herbal formula A every day add 300g, divide to admix in daily ration or the fine fodder for three times and feed behind the mixing, the calving same day of always feeding from antenatal 14 days; Add 300g every of Chinese herbal formula B every day in postpartum, divides to admix in daily ration or the fine fodder for three times and feed behind the mixing, fed the same day after the calving 14 days from calving.
CN2010105403551A 2010-11-12 2010-11-12 Disease-resistant health-care compound Chinese herbal medicinal feed additive for dairy cattle in perinatal period and feeding method Expired - Fee Related CN101971933B (en)

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CN102763781A (en) * 2012-07-31 2012-11-07 河南光泰动物药业有限公司 Nutrient for improving productivity of nursing sows and preparation method thereof
CN103142933A (en) * 2013-03-08 2013-06-12 江苏世盛动物药业有限公司 Chinese herba preparation for treating disease of liver and gall in fish and preparation method thereof
CN103392925A (en) * 2013-07-11 2013-11-20 曾勇 Concentrate supplement special for dairy cow in perinatal period
CN103494990A (en) * 2013-09-23 2014-01-08 大连金鹏畜牧专业合作社 Medicament for preventing and treating chicken liver and kidney diseases and preparation method thereof
CN103720856A (en) * 2014-01-08 2014-04-16 安徽科技学院 Chinese herbal medicine compound preparation for preventing and treating perinatal diseases of milk cows and using method thereof
CN104171366A (en) * 2014-06-30 2014-12-03 安徽省农业科学院畜牧兽医研究所 Feed additive for improving metabolism of dairy cows during perinatal period and production method thereof
CN104222698A (en) * 2014-10-14 2014-12-24 哈尔滨金玉科技开发有限公司 Weight gaining feed additive for beeves
CN104397377A (en) * 2014-11-06 2015-03-11 宣威华安农牧科技开发有限公司 Cattle infectious disease preventing Chinese herbal medicine feed additive
CN104782936A (en) * 2015-03-27 2015-07-22 兰梅 Milk cow feed
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FR3017778A1 (en) * 2014-02-25 2015-08-28 Deltavit ADJUVANT COMPRISING BAICALIN PARTICULARLY FROM AN EXTRACT FROM SCUTELLARIA BAICALENSIS AND ANIMAL FEED COMPRISING SUCH AN ADJUVANT
CN105941855A (en) * 2016-06-16 2016-09-21 济南市动物疫病预防与控制中心 Cow feed additive and application thereof
CN107041339A (en) * 2017-04-22 2017-08-15 金寨奎武生态农业综合开发科技有限公司 A kind of milk cow difficult labour processing method
CN108651706A (en) * 2018-04-23 2018-10-16 内蒙古民族大学 A kind of feed addictive and its production method improving Diseases of Cow metabolism
CN109997965A (en) * 2019-05-23 2019-07-12 湖南农业大学 A kind of compound Chinese herbal medicinal feed additive shortening the milk cow calving interval and feed and application containing the additive
CN114601021A (en) * 2022-03-25 2022-06-10 天津博菲德科技有限公司 Fatty liver resisting medicine for livestock and poultry and Chinese herbal medicine combined fermentation feed additive containing same

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CN102763781A (en) * 2012-07-31 2012-11-07 河南光泰动物药业有限公司 Nutrient for improving productivity of nursing sows and preparation method thereof
CN102763781B (en) * 2012-07-31 2014-02-26 河南光泰动物药业有限公司 Nutrient for improving productivity of nursing sows and preparation method thereof
CN103142933A (en) * 2013-03-08 2013-06-12 江苏世盛动物药业有限公司 Chinese herba preparation for treating disease of liver and gall in fish and preparation method thereof
CN103392925A (en) * 2013-07-11 2013-11-20 曾勇 Concentrate supplement special for dairy cow in perinatal period
CN103494990A (en) * 2013-09-23 2014-01-08 大连金鹏畜牧专业合作社 Medicament for preventing and treating chicken liver and kidney diseases and preparation method thereof
CN103720856A (en) * 2014-01-08 2014-04-16 安徽科技学院 Chinese herbal medicine compound preparation for preventing and treating perinatal diseases of milk cows and using method thereof
US11077127B2 (en) 2014-02-25 2021-08-03 Deltavit Adjuvant containing baicalin, particularly from a Scutellaria baicalensis extract, and animal feed containing such an adjuvant
FR3017778A1 (en) * 2014-02-25 2015-08-28 Deltavit ADJUVANT COMPRISING BAICALIN PARTICULARLY FROM AN EXTRACT FROM SCUTELLARIA BAICALENSIS AND ANIMAL FEED COMPRISING SUCH AN ADJUVANT
WO2015128580A1 (en) 2014-02-25 2015-09-03 Deltavit Adjuvant containing baicalin, particularly from a scutellaria baicalensis extract, and animal feed containing such an adjuvant
RU2694192C2 (en) * 2014-02-25 2019-07-09 Делтавит Additive containing baicalin, in particular from scutellaria baicalensis extract, and animal fodder containing such additive
CN104171366B (en) * 2014-06-30 2017-02-15 安徽省农业科学院畜牧兽医研究所 Feed additive for improving metabolism of dairy cows during perinatal period and production method thereof
CN104171366A (en) * 2014-06-30 2014-12-03 安徽省农业科学院畜牧兽医研究所 Feed additive for improving metabolism of dairy cows during perinatal period and production method thereof
CN104222698A (en) * 2014-10-14 2014-12-24 哈尔滨金玉科技开发有限公司 Weight gaining feed additive for beeves
CN104397377A (en) * 2014-11-06 2015-03-11 宣威华安农牧科技开发有限公司 Cattle infectious disease preventing Chinese herbal medicine feed additive
CN104782941A (en) * 2015-03-27 2015-07-22 兰梅 Preparation method for milk cow feed
CN104782936A (en) * 2015-03-27 2015-07-22 兰梅 Milk cow feed
CN105941855A (en) * 2016-06-16 2016-09-21 济南市动物疫病预防与控制中心 Cow feed additive and application thereof
CN107041339A (en) * 2017-04-22 2017-08-15 金寨奎武生态农业综合开发科技有限公司 A kind of milk cow difficult labour processing method
CN108651706A (en) * 2018-04-23 2018-10-16 内蒙古民族大学 A kind of feed addictive and its production method improving Diseases of Cow metabolism
CN109997965A (en) * 2019-05-23 2019-07-12 湖南农业大学 A kind of compound Chinese herbal medicinal feed additive shortening the milk cow calving interval and feed and application containing the additive
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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120627

CF01 Termination of patent right due to non-payment of annual fee