CN101971855A - Synergistic insecticidal composite with dinotefuran - Google Patents
Synergistic insecticidal composite with dinotefuran Download PDFInfo
- Publication number
- CN101971855A CN101971855A CN2010105643396A CN201010564339A CN101971855A CN 101971855 A CN101971855 A CN 101971855A CN 2010105643396 A CN2010105643396 A CN 2010105643396A CN 201010564339 A CN201010564339 A CN 201010564339A CN 101971855 A CN101971855 A CN 101971855A
- Authority
- CN
- China
- Prior art keywords
- mti
- carbaryl
- mobucin
- bassa
- mtmc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002195 synergetic effect Effects 0.000 title claims abstract description 23
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 13
- 239000002131 composite material Substances 0.000 title abstract description 32
- YKBZOVFACRVRJN-UHFFFAOYSA-N dinotefuran Chemical compound [O-][N+](=O)\N=C(/NC)NCC1CCOC1 YKBZOVFACRVRJN-UHFFFAOYSA-N 0.000 title abstract description 4
- 229960005286 carbaryl Drugs 0.000 claims abstract description 44
- CVXBEEMKQHEXEN-UHFFFAOYSA-N carbaryl Chemical compound C1=CC=C2C(OC(=O)NC)=CC=CC2=C1 CVXBEEMKQHEXEN-UHFFFAOYSA-N 0.000 claims abstract description 44
- DIRFUJHNVNOBMY-UHFFFAOYSA-N fenobucarb Chemical compound CCC(C)C1=CC=CC=C1OC(=O)NC DIRFUJHNVNOBMY-UHFFFAOYSA-N 0.000 claims abstract description 44
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 17
- 239000000843 powder Substances 0.000 claims description 53
- 238000009736 wetting Methods 0.000 claims description 38
- 239000000203 mixture Substances 0.000 claims description 36
- 239000000375 suspending agent Substances 0.000 claims description 28
- 239000004562 water dispersible granule Substances 0.000 claims description 28
- 230000000361 pesticidal effect Effects 0.000 claims description 17
- 235000007164 Oryza sativa Nutrition 0.000 claims description 9
- 235000009566 rice Nutrition 0.000 claims description 9
- 239000000945 filler Substances 0.000 claims description 6
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- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 235000013311 vegetables Nutrition 0.000 claims description 2
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- 239000000306 component Substances 0.000 claims 1
- 239000000575 pesticide Substances 0.000 abstract description 11
- 241001124076 Aphididae Species 0.000 abstract description 9
- VOEYXMAFNDNNED-UHFFFAOYSA-N metolcarb Chemical compound CNC(=O)OC1=CC=CC(C)=C1 VOEYXMAFNDNNED-UHFFFAOYSA-N 0.000 abstract description 7
- 241001414720 Cicadellidae Species 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 4
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- 238000001228 spectrum Methods 0.000 abstract description 3
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- 244000144972 livestock Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 31
- 238000012360 testing method Methods 0.000 description 22
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- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 9
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- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 7
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- 206010067482 No adverse event Diseases 0.000 description 4
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- 229910052791 calcium Inorganic materials 0.000 description 4
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- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 4
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- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 4
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- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
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- 229910000162 sodium phosphate Inorganic materials 0.000 description 3
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- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 3
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 3
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 2
- 239000005639 Lauric acid Substances 0.000 description 2
- 241001249129 Scirpophaga incertulas Species 0.000 description 2
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- 150000001298 alcohols Chemical class 0.000 description 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
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- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
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- 229960002715 nicotine Drugs 0.000 description 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 2
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- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 2
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- FNRMMDCDHWCQTH-UHFFFAOYSA-N 2-chloropyridine;3-chloropyridine;4-chloropyridine Chemical compound ClC1=CC=NC=C1.ClC1=CC=CN=C1.ClC1=CC=CC=N1 FNRMMDCDHWCQTH-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a synergistic insecticidal composite with dinotefuran. The synergistic insecticidal composite is an insecticidal composite containing a component A and a component B, wherein the component A is dinotefuran; the component B is selected from any one of the following insecticides: metolcarb, isoprocarb, fenobucarb and carbaryl; the weight ratio of the active component A to the active component B is 1-50:1-80. The insecticidal composite can control various pests, have obvious synergy, expand the insecticidal spectrum and have higher activity to piercing-sucking mouthparts pests such as aphid, planthopper, leafhopper and whitefly and lepidoptera pests such as Plutella xylostella and Spodoptera exigua; the dosage of the pesticide is decreased, the amount of residue of the pesticide on crops is decreased and the environmental pollution is reduced; and the insecticidal composite is safe to human and livestock and has good environment compatibility, and the pests are not easy to have drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of Synergistic insecticidal compositions that contains MTI-446.
Background technology
MTI-446, English common name (dinotefuran), chemical name 1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine.The chemical constitution of itself and existing nicotinic insecticide is far from each other, and chloro-pyridine base, chloro thiazolyl before its tetrahydrofuran base has replaced do not contain the halogen family element.Simultaneously, also different at aspect of performance with nicotine.So people are referred to as " furans nicotine " at present.This medicament insecticidal spectrum is wide, has remarkable interior suction osmosis, and has promptly shown very high insecticidal activity at very low dosage.This medicament is fool proof to mammal, birds and aquatile, and crop is not had poisoning, can be used for numerous crops such as paddy rice, fruit tree, vegetables.
Yet in the real process of agricultural production, the problem that pest control is easy to generate most is the generation of pest resistance to insecticide.Important insect such as lepidoptera pest are because its breeding cycle is short, and breeding amount is big, and mobility is little on the agricultural, and selfing degree height is easy to generate resistance especially.
The different cultivars composition carries out composite, is the very common method of control resistant insect.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, co-toxicity coefficient very high composite just still less.Through inventor research, find MTI-446 and meta-tolyl-N-methylcarbamate (MTMC), Mobucin, Bassa and carbaryl can produce good synergistic effect after composite, and still unexposed about the composite relevant report of MTI-446 and meta-tolyl-N-methylcarbamate (MTMC), Mobucin, Bassa and carbaryl.
Summary of the invention
Degradation problem under the resistance generation that the long-term use of the single agent of MTI-446 may bring, the drug effect, the Pesticidal combination that the present invention proposes contains two kinds of active components of A, B, and an amount of surfactant and carrier, effective active composition A, effective active composition B percentage by weight are 1～50: 1～80.
Described a kind of Pesticidal combination that contains MTI-446 is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～30: 5～60.
Active component A is selected from MTI-446, and active component B is meta-tolyl-N-methylcarbamate (MTMC), Mobucin, Bassa, carbaryl.
The described Pesticidal combination that contains MTI-446 is characterized in that: the percentage by weight of MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) is 5～30: 10～60.
The described Pesticidal combination that contains MTI-446 is characterized in that: the percentage by weight of MTI-446 and Mobucin is 5～30: 10～60.
The described Pesticidal combination that contains MTI-446 is characterized in that: the percentage by weight of MTI-446 and Bassa is 5～30: 10～60.
The described Pesticidal combination that contains MTI-446 is characterized in that: the percentage by weight of MTI-446 and carbaryl is 5～30: 10～60.
The ratio of weight and number of A, two kinds of active components of B is 1～50: 1～80.Usually active weight percentage is 0.5～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the Pesticidal combination of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of Pesticidal combination of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, binding agent or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, the defoamer etc. one or more again.
Pesticidal combination of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent.
When making wetting powder, composition comprises following constituent content: MTI-446 1～50%, active component B1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%.
Active component MTI-446, B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: active component MTI-446 1～50%, B1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～90%.
Active component MTI-446, B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
Comprise following constituent content when composition is made suspending agent: active component MTI-446 1～20%, B1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active component MTI-446, B, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes the suspending agent product of the present composition.
The invention has the advantages that: after (1) MTI-446 and active component B are composite, have notable synergistic and lasting effect; (2) enlarged insecticidal spectrum, to aphid, rice fulgorid, rice leaf roller, and lepidoptera pest such as diamond-back moth, beet armyworm, cotton bollworm etc. all have greater activity; (3) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; (4), insect good to person poultry safety, Environmental compatibility is difficult for developing immunity to drugs.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Application Example one
Example one 55% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powder
MTI-446 5%, meta-tolyl-N-methylcarbamate (MTMC) 50%, naphthalene sulfonic acid-formaldehyde condensation product 4%, polycarboxylate 2%, wetting and penetrating agent F 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 55% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powder.
Example 2 38% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powders
MTI-446 3%, meta-tolyl-N-methylcarbamate (MTMC) 35%, lignosulfonates 5%, lauryl sodium sulfate 3%, soapberry powder 2%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 38% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powder.
Example 3 63% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powders
MTI-446 3%, meta-tolyl-N-methylcarbamate (MTMC) 60%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, Nekal BX 4%, white carbon 5%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 63% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powder.
Example 4 82% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powders
MTI-446 2%, meta-tolyl-N-methylcarbamate (MTMC) 80%, lignosulfonates 4%, spaonin powder 3%, white carbon 2%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 82% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) wetting powder.
Example 5 42% MTI-446 Tsumacide water dispersible granules
MTI-446 2%, meta-tolyl-N-methylcarbamate (MTMC) 40%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, moistening bleeding agent F4%, ammonium sulfate 2%, starch 6%, bentonite add to 100%, the mixed 42% MTI-446 Tsumacide water dispersible granule that gets.
Example 6 45% MTI-446 Tsumacide water dispersible granules
MTI-446 30%, meta-tolyl-N-methylcarbamate (MTMC) 15%, aliphatic amine polyoxyethylene are phonetic 6%, neopelex 4%, sodium carbonate 2%, starch 12%, kaolin add to 100%, mixed 45% MTI-446 Tsumacide water dispersible granule.
Example 7 52% MTI-446 Tsumacide water dispersible granules
MTI-446 50%, meta-tolyl-N-methylcarbamate (MTMC) 2%, lignosulfonates 5%, tea are withered 2%, ammonium sulfate 8%, diatomite add to 100%, mixed 52% MTI-446 Tsumacide water dispersible granule.Example 8 20% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) suspending agents
MTI-446 10%, meta-tolyl-N-methylcarbamate (MTMC) 10%, draw back powder 5%, sodium lignin sulfonate 3%, DBSA 4%, silicone compound 0.3%, gelatin 0.5%, deionized water adds to 100%, mixed 20% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) suspending agent.
Example 9 22% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) suspending agents
MTI-446 2%, meta-tolyl-N-methylcarbamate (MTMC) 20%, lignosulfonates 4%, moistening bleeding agent F 5%, silicone oil 0.2%, gum Arabic 0.5%, propane diols 3%, deionized water add to 100%, the mixed 22% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) suspending agent that gets.
Example ten 41% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) suspending agents
MTI-446 1%, meta-tolyl-N-methylcarbamate (MTMC) 40%, lignosulfonates 6%, neopelex 2%, C
8～10Aliphatic alcohols 0.3%, polyvinylpyrrolidone 0.5%, polyethylene glycol 2%, deionized water add to 100%, the mixed 41% MTI-446 meta-tolyl-N-methylcarbamate (MTMC) suspending agent that gets.
Example ten one 48% MTI-446 Mobucin wetting powders
MTI-446 4%, Mobucin 44%, poly-hydroxy acid salt 8%, tea are withered 3%, white carbon 3%, kaolin add to 100%, and production technology makes 48% MTI-446 Mobucin wetting powder routinely.
Example ten two 55% MTI-446 Mobucin wetting powders
MTI-446 5%, Mobucin 10%, naphthalene sulfonic acid-formaldehyde condensation product 8%, lauryl sodium sulfate 2%, bentonite add to 100%, and production technology makes 55% MTI-446 Mobucin wetting powder routinely.
Example ten three 62% MTI-446 Mobucin wetting powders
MTI-446 6%, Mobucin 56%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, spaonin powder 2%, white carbon 5%, diatomite adds to 100%, and production technology makes 62% MTI-446 Mobucin wetting powder routinely.
Example ten four 25% MTI-446 Mobucin water dispersible granules
MTI-446 5%, Mobucin 20%, alkylaryl APEO 8%, neopelex 5%, ammonium sulfate 2%, starch 8%, bentonite add to 100%, the mixed 25% MTI-446 Mobucin water dispersible granules that gets.
Example ten five 39% MTI-446 Mobucin water dispersible granules
MTI-446 3%, Mobucin 36%, sodium lignin sulfonate 6%, lauryl sodium sulfate 4%, draw back powder 2%, ammonium sulfate 5%, starch 6%, kaolin and add to 100%, mixed 39% MTI-446 Mobucin water dispersible granules.
Example ten six 60% MTI-446 Mobucin water dispersible granules
MTI-446 4%, Mobucin 56%, alkylphenol-polyethenoxy are phonetic 5%, DBSA 2%, urea 2%, diatomite add to 100%, mixed 60% MTI-446 Mobucin water dispersible granules.
Example ten seven 21% MTI-446 Mobucin suspending agents
MTI-446 1%, Mobucin 20%, polycarboxylate 3%, sodium lignin sulfonate 5%, DBSA 2%, silicone oil 0.2%, gum Arabic 0.4%, deionized water adds to 100%, the mixed 21% MTI-446 Mobucin suspending agent that gets.
Example ten eight 35% MTI-446 Mobucin suspending agents
MTI-446 5%, Mobucin 30%, lignosulfonates 4%, spaonin powder 5%, silicone compound 05%, polyvinyl alcohol 0.2%, propane diols 1%, deionized water add to 100%, the mixed 35% MTI-446 Mobucin suspending agent that gets.
Example ten nine 45% MTI-446 Mobucin suspending agents
MTI-446 10%, Mobucin 35%, lignosulfonates 4%, lauryl sodium sulfate 3%, lauric acid 0.3%, xanthans 0.5%, glycerine 4%, deionized water add to 100%, the mixed 45% MTI-446 Mobucin suspending agent that gets.
Example two ten 55% MTI-446 Bassa wetting powders
MTI-446 25%, Bassa 30%, two sodium naphthasulfonate 7%, neopelex 5%, soapberry powder 2%, kaolin add to 100%, and production technology makes 55% MTI-446 Bassa wetting powder routinely.
Example two ten one 45% MTI-446 Bassa wetting powders
MTI-446 30%, Bassa 15%, lauryl sodium sulfate 2%, alkylnaphthalene sulfonate formaldehyde condensation products 1%, white carbon 2%, attapulgite add to 100%, and production technology makes 45% MTI-446 Bassa wetting powder routinely.
Example two ten two 75% MTI-446 Bassa wetting powders
MTI-446 20%, Bassa 55%, dodecyl polyoxyethylene ether phosphate 5%, tea are withered 4%, white carbon 5%, diatomite add to 100%, and production technology makes 75% MTI-446 Bassa wetting powder routinely.
Example two ten three 30% MTI-446 Bassa water dispersible granules
MTI-446 15%, Bassa 15%, lignosulfonates 5%, draw back powder 3%, starch 8%, ammonium sulfate 2%, polyvinyl alcohol 0.5%, kaolin and add to 100%, production technology makes 30% MTI-446 Bassa water dispersible granules routinely.
Example two ten four 40% MTI-446 Bassa water dispersible granules
MTI-446 5%, Bassa 35%, lauryl sodium sulfate 5%, poly-hydroxy acid salt 6%, urea 1%, sodium carbonate 6%, sodium phosphate trimer 0.5%, bentonite add to 100%, and production technology makes 40% MTI-446 Bassa water dispersible granules routinely.
Example two ten five 44% MTI-446 Bassa water dispersible granules
Add to 100% by MTI-446 4%, Bassa 40%, neopelex 5%, sodium lignin sulfonate 6%, urea 1%, ammonium sulfate 10%, polyvinyl alcohol 0.3%, kaolin, production technology makes 44% MTI-446 Bassa water dispersible granules routinely.
Example two ten six 18% MTI-446 Bassa suspending agents
MTI-446 3%, Bassa 15%, alkyl benzene sulfonate calcium salt 6%, draw back powder 3%, silicone oil 0.2%, sodium phosphate trimer 0.6%, deionized water adds to 100%, mixed 18% MTI-446 Bassa suspending agent.
Example two ten seven 33% MTI-446 Bassa suspending agents
MTI-446 3%, Bassa 30%, poly-hydroxy acid salt 6%, soapberry powder 5%, gelatin 0.3%, silicone compound 0.3%, polyethylene glycol 0.4%, deionized water adds to 100%, the mixed 33% MTI-446 Bassa suspending agent that gets.
Example two ten eight 46% MTI-446 Bassa suspending agents
MTI-446 2%, Bassa 44%, dodecyl benzene sulfonate 8%, tea are withered 5%, lauric acid 0.4%, polyvinylpyrrolidone 0.2%, ethylene glycol 3%, deionized water add to 100%, mixed 46% MTI-446 Bassa suspending agent.
Example two ten nine 52% MTI-446 carbaryl wetting powders
MTI-446 4%, carbaryl 48%, sodium lignin sulfonate 3%, polyvinylpyrrolidone 2%, wetting agent F5%, white carbon 3%, kaolin adds to 100%, and production technology makes 52% MTI-446 carbaryl wetting powder routinely.
Example three ten 50% MTI-446 carbaryl wetting powders
MTI-446 15%, carbaryl 35%, alkyl benzene sulfonate calcium salt 5%, draw back powder 4%, bentonite adds to 100%, production technology makes 50% MTI-446 carbaryl wetting powder routinely.
Example three ten one 65% MTI-446 carbaryl wetting powders
MTI-446 10%, carbaryl 55%, poly-hydroxy acid salt 8%, calcium dodecyl benzene sulfonate 5%, draw back powder 2%, white carbon 2%, diatomite adds to 100%, and production technology makes 65% MTI-446 carbaryl wetting powder routinely.
Example three ten two 39% MTI-446 carbaryl water dispersible granules
MTI-446 3%, carbaryl 36%, sodium lignin sulfonate 8%, tea are withered 4%, urea 3%, ammonium sulfate 2%, polyethylene glycol 1%, kaolin add to 100%, and production technology makes 39% MTI-446 carbaryl water dispersible granules routinely.
Example three ten three 40% MTI-446 carbaryl water dispersible granules
MTI-446 30%, carbaryl 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, polyoxyethylene carboxylate 2%, xanthans 1%, sodium carbonate 10%, bentonite add to 100%, and production technology makes 40% MTI-446 carbaryl water dispersible granules routinely.
Example three ten four 57% MTI-446 carbaryl water dispersible granules
MTI-446 3%, carbaryl 54%, alkyl benzene sulfonate calcium salt 4%, draw back powder 2%, urea 1%, sodium carbonate 10%, polyvinylpyrrolidone 0.3%, kaolin and add to 100%, production technology makes 57% MTI-446 carbaryl water dispersible granules routinely.
Example three ten five 35% MTI-446 carbaryl suspending agents
MTI-446 5%, carbaryl 30%, sodium lignin sulfonate 8%, spaonin powder 4%, silicone compound 0.3%, sodium carboxymethylcellulose 0.4%, deionized water adds to 100%, the mixed 35% MTI-446 carbaryl suspending agent that gets.
Example three ten six 20% MTI-446 carbaryl suspending agents
MTI-446 10%, carbaryl 10%, polycarboxylate 8%, soapberry powder 5%, xanthans 0.6%, polyvinyl alcohol 0.3%, propane diols 2%, deionized water add to 100%, the mixed 20% MTI-446 carbaryl suspending agent that gets.
Example three ten seven 28% MTI-446 carbaryl suspending agents
MTI-446 4%, carbaryl 24%, neopelex 8%, tea are withered 5%, silicone oil 0.3%, polyethylene glycol 0.3%, ethylene glycol 3%, deionized water add to 100%, mixed 28% MTI-446 carbaryl suspending agent.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC＜80 are antagonism, and 80≤CTC≤120 are summation action, and CTC＞120 are synergistic effect, on this basis, carry out field trial again.
Test method: respectively the mother liquor of each mixed agent of MTI-446 effective active composition B is diluted to five series concentration during test, places beaker standby respectively.Adopt and to soak the method that connects worm behind the leaf earlier, the blade of the same size that does not contact any medicament soaked in the soup that configures behind the 5s take out, dry naturally, put into insect box, connect then, under 25 ℃ of conditions, raise for examination 3 instar larvaes, every processing repeats for 3 times, every to repeat used examination borer population be 20, establishes blank simultaneously, checks dead borer population in 72h, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50Value.If the contrast lethality then is considered as invalid test greater than 10%.Computing formula is as follows:
To be converted into probit value (y) for examination insect corrected mortality, concentration of treatment (μ g/ml) converts logarithm value (x) to, draws virulence regression equation with method of least squares, and calculates the value of every kind of medicament thus.Calculate co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula following (with the MTI-446 is the standard medicament, and its toxicity index is 100):
TI * the P of theoretical toxicity index (TTI)=MTI-446 of M
MTI-446TI * P of+effective active composition B
Effective active Composition B
In the formula: M is the mixture of different proportionings
P
Effective active composition BBe effective active composition B shared ratio in composition
P
MTI-446Be MTI-446 shared ratio in composition
A is selected from MTI-446;
B is selected from following any one insecticide: meta-tolyl-N-methylcarbamate (MTMC), Mobucin, Bassa, carbaryl.
Application Example two:
For trying insect: rice-leaf hopper.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining MTI-446, the former medicine of meta-tolyl-N-methylcarbamate (MTMC) and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The different proportionings with meta-tolyl-N-methylcarbamate (MTMC) of table 1 MTI-446 are to the toxicity test of rice-leaf hopper
As shown in Table 1, the proportioning 50: 1 of the composite control of MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) rice-leaf hopper, to 1: 80 o'clock, spend coefficient together all greater than 120, illustrating that both were mixed in the scope at 50: 1 to 1: 80 all shows synergistic effect, especially when the proportioning of MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, spends the coefficient maximum together when MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) weight ratio are 1: 10, and synergistic effect is the most obvious.
Application Example three:
For trying insect: rice hoppers.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining MTI-446, the former medicine of Mobucin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The different proportionings with Mobucin of table 2 MTI-446 are to the toxicity test of rice hoppers
As shown in Table 2, MTI-446 and Mobucin be composite prevents and treats the proportioning 50: 1 of rice hoppers, to 1: 80 o'clock, spend coefficient together all greater than 120, illustrating that both were mixed in the scope at 50: 1 to 1: 80 all shows synergistic effect, especially when the proportioning of MTI-446 and Mobucin during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, spends the coefficient maximum together when MTI-446 and Mobucin weight ratio are 1: 10, and synergistic effect is the most obvious.
Application Example four
For trying insect: the cucumber aphid.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining MTI-446, the former medicine of Bassa and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The different proportionings with Bassa of table 3 MTI-446 are to the toxicity test of cucumber aphid
As shown in Table 3, the proportioning 50: 1 of MTI-446 and fenobucarb composite control cucumber aphid, to 1: 80 o'clock, spend coefficient together all greater than 120, illustrating that both were mixed in the scope at 50: 1 to 1: 80 all shows synergistic effect, especially when the proportioning of MTI-446 and Bassa during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, spends the coefficient maximum together when the weight ratio of MTI-446 and Bassa is 1: 10, and synergistic effect is the most obvious.
Application Example five
For trying insect: cotton aphid.
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective lethal concentration scope of determining MTI-446, the former medicine of carbaryl and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The different proportionings with carbaryl of table 4 MTI-446 are to the toxicity test of cotton aphid
As shown in Table 2, the proportioning 50: 1 of the composite control cotton aphid of MTI-446 and carbaryl, to 1: 80 o'clock, spend coefficient together all greater than 120, illustrating that both were mixed in the scope at 50: 1 to 1: 80 all shows synergistic effect, especially when the proportioning of MTI-446 and carbaryl during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, spends the coefficient maximum together when MTI-446 and carbaryl weight ratio are 1: 10, and synergistic effect is the most obvious.
Application Example six MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) and the composite control apple tree leafhopper test of pesticide effectiveness thereof
This experimental establishment is in apple orchard, Liquan County Pi Zhai township, Xianyang, Shanxi province city, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 20% MTI-446 wetting powder (commercial), 25% meta-tolyl-N-methylcarbamate (MTMC) wetting powder (commercial).
Investigation apple tree leafhopper insect pest index in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect before the medicine.Experimental result is as follows:
Table 5 MTI-446, meta-tolyl-N-methylcarbamate (MTMC) and the composite control apple tree leafhopper test of pesticide effectiveness thereof
As can be seen from Table 5, energy effectively preventing and treating apple-tree leafhopper after MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven MTI-446 and Mobucin and the composite control Chinese cabbage aphid test of pesticide effectiveness thereof
This experimental establishment is in Chinese cabbage base, Jiangzhou, Qingdao City, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 20% MTI-446 wetting powder (commercial), 20% Mobucin missible oil (commercial).
Investigation Chinese cabbage aphid evil index in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect before the medicine.Experimental result is as follows:
Table 6 MTI-446, Mobucin and the composite control Chinese cabbage aphid test of pesticide effectiveness thereof
As can be seen from Table 6, can effectively prevent and treat the Chinese cabbage aphid after MTI-446 and Mobucin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight MTI-446 and Bassa and the composite rice hoppers test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at suburb, Jiujiang City, Jiangxi Province one paddy field, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 20% MTI-446 wetting powder (commercial), 25% Bassa missible oil (commercial).
Investigation rice hoppers insect pest index before the medicine in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect.Experimental result is as follows:
Table 7 MTI-446, Bassa and the composite rice hoppers test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 7, can effectively prevent and treat rice hoppers behind MTI-446 and the fenobucarb composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects, and to rice-stem borer, paddy stem borer has certain preventive effect.
Application Example nine MTI-446 and carbaryl and the composite control cotton aphid test of pesticide effectiveness thereof
This experimental establishment is on cotton planting ground, Linyi, Shandong Province county, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 20% MTI-446 wetting powder (commercial), 25% carbaryl wetting powder (commercial).
Investigation cotton aphid insect pest index before the medicine in the their early stage dispenser, was investigated the insect pest indexes in 24 hours, 72 hours after the dispenser and is calculated preventive effect.Experimental result is as follows:
Table 8 MTI-446, carbaryl and the composite control cotton aphid test of pesticide effectiveness thereof
As can be seen from Table 8, can effectively prevent and treat cotton aphid after MTI-446 and carbaryl are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Claims (9)
1. Synergistic insecticidal compositions that contains MTI-446, comprise effective active component, auxiliary agent and filler, it is characterized in that: A, B percentage by weight are 1～50: 1～80, and described A is selected from MTI-446, and B is selected from meta-tolyl-N-methylcarbamate (MTMC), Mobucin, Bassa, carbaryl.
2. a kind of Pesticidal combination that contains MTI-446 according to claim 1 is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～30: 5～60.
3. according to the described Pesticidal combination that contains MTI-446 of claim 2, it is characterized in that: the percentage by weight of MTI-446 and meta-tolyl-N-methylcarbamate (MTMC) is 5～30: 10～60.
4. according to the described Pesticidal combination that contains MTI-446 of claim 2, it is characterized in that: the percentage by weight of MTI-446 and Mobucin is 5～30: 10～60.
5. according to the described Pesticidal combination that contains MTI-446 of claim 2, it is characterized in that: the percentage by weight of MTI-446 and Bassa is 5～30: 10～60.
6. according to the described Pesticidal combination that contains MTI-446 of claim 2, it is characterized in that: the percentage by weight of MTI-446 and carbaryl is 5～30: 10～60.
7. according to the Pesticidal combination of the described MTI-446 that contains of claim 1, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent.
8. the MTI-446 Pesticidal combination that contains according to claim 1 is in the application of control aspect the crop pests.
9. the MTI-446 Pesticidal combination that contains according to claim 1 is mainly used in control paddy rice, vegetables, cotton, fruit various pests.
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| CN104642372A (en) * | 2015-02-09 | 2015-05-27 | 安徽海日农化有限公司 | Dinotefuran and isoprocarb compound suspending agent and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101036464A (en) * | 2002-02-21 | 2007-09-19 | 拜尔农作物科学股份公司 | Synergistic insecticidal mixtures |
| JP2008179542A (en) * | 2007-01-23 | 2008-08-07 | Sumika Enviro-Science Co Ltd | Granular water-dispersible powder |
| CN102415404A (en) * | 2010-09-28 | 2012-04-18 | 南京华洲药业有限公司 | Composite insecticidal composition containing dinotefuran and isoprocarb and purpose thereof |
| CN102415403A (en) * | 2010-09-28 | 2012-04-18 | 南京华洲药业有限公司 | Composite pesticidal composition containing dinotefuran and MTMC and application thereof |
| CN102415402A (en) * | 2010-09-28 | 2012-04-18 | 南京华洲药业有限公司 | Compound insecticidal composition containing dinotefuran and fenobucarb and application thereof |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101036464A (en) * | 2002-02-21 | 2007-09-19 | 拜尔农作物科学股份公司 | Synergistic insecticidal mixtures |
| JP2008179542A (en) * | 2007-01-23 | 2008-08-07 | Sumika Enviro-Science Co Ltd | Granular water-dispersible powder |
| CN102415404A (en) * | 2010-09-28 | 2012-04-18 | 南京华洲药业有限公司 | Composite insecticidal composition containing dinotefuran and isoprocarb and purpose thereof |
| CN102415403A (en) * | 2010-09-28 | 2012-04-18 | 南京华洲药业有限公司 | Composite pesticidal composition containing dinotefuran and MTMC and application thereof |
| CN102415402A (en) * | 2010-09-28 | 2012-04-18 | 南京华洲药业有限公司 | Compound insecticidal composition containing dinotefuran and fenobucarb and application thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104642372A (en) * | 2015-02-09 | 2015-05-27 | 安徽海日农化有限公司 | Dinotefuran and isoprocarb compound suspending agent and preparation method thereof |
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| CN101971855B (en) | 2013-10-09 |
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