CN101965394B - 开放连续模式的细胞培养的方法和装置 - Google Patents

开放连续模式的细胞培养的方法和装置 Download PDF

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Publication number
CN101965394B
CN101965394B CN200980105991.7A CN200980105991A CN101965394B CN 101965394 B CN101965394 B CN 101965394B CN 200980105991 A CN200980105991 A CN 200980105991A CN 101965394 B CN101965394 B CN 101965394B
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culture
culture vessel
cell
cultivation
instrument
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Chinese (zh)
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CN101965394A (zh
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B·库德拉
P-Y·柴斯纳奥
Y·比奥尤安
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Mei Tabai Liu Mu Co
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Mei Tabai Liu Mu Co
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN200980105991.7A 2008-02-21 2009-02-20 开放连续模式的细胞培养的方法和装置 Expired - Fee Related CN101965394B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0851123A FR2927906B1 (fr) 2008-02-21 2008-02-21 Procede et dispositif de culture cellulaire en mode continu ouvert.
FR0851123 2008-02-21
PCT/FR2009/050275 WO2009112739A1 (fr) 2008-02-21 2009-02-20 Procédé et dispositif de culture cellulaire en mode continu ouvert

Publications (2)

Publication Number Publication Date
CN101965394A CN101965394A (zh) 2011-02-02
CN101965394B true CN101965394B (zh) 2015-06-17

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CN200980105991.7A Expired - Fee Related CN101965394B (zh) 2008-02-21 2009-02-20 开放连续模式的细胞培养的方法和装置

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Country Link
US (1) US9018007B2 (cg-RX-API-DMAC7.html)
EP (1) EP2247712A1 (cg-RX-API-DMAC7.html)
JP (1) JP5620278B2 (cg-RX-API-DMAC7.html)
CN (1) CN101965394B (cg-RX-API-DMAC7.html)
AU (1) AU2009224507B2 (cg-RX-API-DMAC7.html)
CA (1) CA2714186A1 (cg-RX-API-DMAC7.html)
FR (1) FR2927906B1 (cg-RX-API-DMAC7.html)
IL (1) IL207653A (cg-RX-API-DMAC7.html)
NZ (1) NZ587479A (cg-RX-API-DMAC7.html)
WO (1) WO2009112739A1 (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8597941B2 (en) * 2009-09-04 2013-12-03 The Regents Of The University Of California Bioreactor for quantification of headspace VOC content from cultures
CA2840947A1 (en) * 2011-07-07 2013-01-10 Dow Agrosciences Llc Variable gas source gas exchange system
CN102796704B (zh) * 2012-08-31 2014-06-25 北京天辰空间生物医药研发有限公司 一种温度控制细胞培养方法
SG11201502926TA (en) * 2012-10-26 2015-05-28 Massachusetts Inst Technology Humidity control in chemical reactors
CN105683354A (zh) 2013-08-23 2016-06-15 麻省理工学院 具有基本上恒定的工作体积的小体积生物反应器及相关系统和方法
CA2961133A1 (en) * 2014-09-19 2016-03-24 Sekisui Chemical Co., Ltd. Microorganism culture method and culture apparatus
JP6339005B2 (ja) * 2014-12-25 2018-06-06 徳島県 変異酵母の製造方法、変異酵母及びこれらの利用、ならびに微生物変異用uv−led照射装置
CN104962474B (zh) * 2015-06-29 2019-06-21 新奥科技发展有限公司 一种藻类细胞的培养方法
CN111139216B (zh) * 2018-11-01 2024-09-03 上海药明生物技术有限公司 高通量、自动化的细胞连续培养方法及其应用
JP2021000018A (ja) * 2019-06-20 2021-01-07 シンフォニアテクノロジー株式会社 細胞分注装置及び細胞分注方法
JP7481608B2 (ja) * 2019-06-20 2024-05-13 シンフォニアテクノロジー株式会社 細胞培養装置
FR3110596B1 (fr) * 2020-05-21 2024-11-08 Altar Procédé de culture cellulaire en continu de cellules vivantes pour l’évolution adaptative desdites cellules vivantes.
CN115350027B (zh) * 2022-07-12 2024-04-09 浙江大学医学院附属第一医院 一种便携式可爬楼picc居家维护操作车
US20250250549A1 (en) * 2024-02-02 2025-08-07 Culture Biosciences, Inc. Systems and methods for viral transfection of cells in a bioreactor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686194B1 (en) * 1998-12-04 2004-02-03 Institut Pasteur Method and device for selecting accelerated proliferation of living cells in suspension
CN1778887A (zh) * 2005-10-09 2006-05-31 南京工业大学 一种高密度细胞培养方法及其生物反应装置
CN1807599A (zh) * 2006-01-12 2006-07-26 上海交通大学 安全连续封闭式细胞培养、病毒生产/灭活的方法

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JPS6374283A (ja) * 1986-09-17 1988-04-04 Nec Corp クロツク再生方式
DK1740693T3 (da) * 2004-02-23 2012-08-27 Crecy Eudes Francois Marie De Kontinuerligt kulturapparat med bevægelig beholder tilladende udvælgelse af filter-cellevarianter
US20070037276A1 (en) * 2004-02-23 2007-02-15 Eudes Francois Marie De Crecy Continuous culture apparatus with mobile vessel, allowing selection of fitter cell variants and producing a culture in a continuous manner
DE102004035752A1 (de) * 2004-07-23 2006-03-16 Tridonicatco Gmbh & Co. Kg Verfahren zur Kontrolle von Übertragungen einer bidirektionalen Schnittstelle
AU2006226992A1 (en) * 2005-03-22 2006-09-28 Irm Llc Compound profiling devices, systems, and related methods
WO2006130670A1 (en) * 2005-06-01 2006-12-07 Irm Llc Cell culture flasks, systems, and methods for automated processing

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686194B1 (en) * 1998-12-04 2004-02-03 Institut Pasteur Method and device for selecting accelerated proliferation of living cells in suspension
CN1778887A (zh) * 2005-10-09 2006-05-31 南京工业大学 一种高密度细胞培养方法及其生物反应装置
CN1807599A (zh) * 2006-01-12 2006-07-26 上海交通大学 安全连续封闭式细胞培养、病毒生产/灭活的方法

Also Published As

Publication number Publication date
FR2927906A1 (fr) 2009-08-28
AU2009224507B2 (en) 2014-05-01
US9018007B2 (en) 2015-04-28
IL207653A0 (en) 2010-12-30
AU2009224507A1 (en) 2009-09-17
EP2247712A1 (fr) 2010-11-10
IL207653A (en) 2014-09-30
CA2714186A1 (fr) 2009-09-17
NZ587479A (en) 2012-10-26
CN101965394A (zh) 2011-02-02
JP5620278B2 (ja) 2014-11-05
WO2009112739A1 (fr) 2009-09-17
FR2927906B1 (fr) 2010-04-02
JP2011512148A (ja) 2011-04-21
US20110003390A1 (en) 2011-01-06

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