CN101961412A - Medicinal preparation for external use for strengthening treatment on verrucas by Chinese traditional medicines comprising nano-silver and selenium elements - Google Patents
Medicinal preparation for external use for strengthening treatment on verrucas by Chinese traditional medicines comprising nano-silver and selenium elements Download PDFInfo
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Abstract
The invention discloses a medicinal preparation for external use for strengthening the treatment on verrucas by Chinese traditional medicines comprising nano-silver and selenium elements, which belongs to the technical field of preparing new medicines for treating various verrucas by Chinese traditional medicines comprising nano-silver and selenium elements, wherein the verrucas is a benign skin tumor infected by human papillomavirus (HPV), and a neoplasm generated on the surface of the skin. The treatment by Chinese traditional medicines focuses on clearing heat and detoxicating, destroying parasites, activating blood and softening hardness. Based on traditional medication, and through adopting the latest nanotechnology and the element balance medicine, and adding broad-spectrum and high-effect nano silver series antibacterial agents '(AT) antibacterial agent' and organic, inorganic and natural plant antibacterial medicinal materials as well as selenium and zinc elements and the like which can boost the immune function of human body, the medicinal preparation of the invention is used for the external treatment of various verrucas, and has a particular effect.
Description
Technical field:
Reinforced nano silver selenium element Chinese medicine of the present invention is controlled the topical agent of wart class, belongs to the new drug preparation production technical field of the various wart classes of modern nano silver, selenium element external therapy of Chinese herb.
Background technology:
Condyloma acuminatum, verruca vulgaris, verruca plana, infectious warts etc. are the mucocutaneous a kind of benign skin tumour that through 3～5 month incubation period generate of a kind of human papillomavirus (HPV) by the trickle damage of human body.Condyloma acuminatum claims sharp Gui condyloma latum again, genital wart, genital wart, can cause with genitals, anuses etc. are located the common property infectious disease that verrucous vegetation is a feature, crowd's sickness rate that primary disease and property are enlivened is higher, sending out the age well is 16～35 years old, predilection site mainly is distributed in the glans penis urethral orifice, foreskin, bandit's shape ditch, frenulum of prepuce and crissum, women's skin lesion mainly is distributed in big nympha, vaginal orifice, urethral orifice, anus or pudendum, occasionally in axillary fossa, omphalos, breast etc. are located, concurrent skin lesion, 3～5 at least, 30～40 at most, skin lesion is cauliflower form or is mamillary, Tan shape wart (the most common).Shape wart, flat wart etc. are examined in circular mound, belong to the categories such as " condyloma acuminatum ", " shy wart " of the traditional Chinese medical science.
Verruca vulgaris (verruca vulgaris) also is a kind of of wart, be more common in child and youth, the good finger of sending out, the back of the hand, also be found in women's head-ornaments portion, local skin lesion is the keratogenous protuberance vegetation of skin superficial, little of Semen setariae, big as Semen Glycines, protuberate, color is greyish white or dirty Huang, the surface is fluffy withered, shape such as pistil, 1～2 place at least, tens of at most places, sometimes can be the shape of trooping, the life that has can spread under first fingernail edge person, can be with fingernail jack-up during increase, its rough surface is as thorn, main cause also is due to human papillomavirus infects, and it can be by directly or indirectly as infections such as pollutant, and the traditional Chinese medical science claims " verruca ", " withered muscle arrow ", " verruca vulgaris ", " unlucky skin ulcer ", " verruca vulgaris ", " verruca vulgaris ".This claims plantar wart if occur in the vola, and the compressing pain is arranged, and the person claims periungual wart if betide the nail margin, and flexible elongated is so claim " verruca filiformis " again.Primary disease is after former mother wart is cured, and the sub-wart of supervention can be died away or come off sometimes around it.The infringement that betides scalp is the digitation that is of single or multiple stack ups, the tip is the cutin sample, Chang Yin scratches, and dredges broken wound of head and hemorrhage, and the treatment doctor trained in Western medicine is mainly taked antitumor, antiviral or with the treatment of corrosive medicine or physical therapy, operation, immune formulation etc.
Verruca plana also is a kind of common viral vegetation, is a kind of infringement dermatosis, mostly occurs on teen-age face, and erythra is the flat pimple of sorghum grain size, and boundary is clear, is yellowish-brown or makes skin of face present point-like brown spot a little more than skin.Very then face presents dark and gloomy mottle, and skin lesion is projected on skin surface, is sowing shape or wire and distributes, and smooth surface is shinny, and that touches loses smooth feeling, the companion's pruritus that has, and then the patient is unconscious scratches with hands.This patient is more common in adolescence, particularly the women is also caused by human papillomavirus, can directly or indirectly be infected by the external world, also can scratch skin lesion and self inoculation causes by the patient.Therefore avoid skin injury, cross infection is very important.Skin lesion is from the beginning of as foxtail millet grain, sesame seed sample, pimple cumulative big as grain of rice shape or silk bean shape, and the how intensive appearance of flat pimple is the chronic course of disease, the natural spontaneous recovery of energy or disappear suddenly, but also might continue not heal for many years, generally do not stay spot after healing.Molluscum contagiosum is commonly called as " molluscum contagiosum ", and the traditional Chinese medical science claims " molluscum contagiosum ", sends out the vegetation that reaches omphalos in the thoracic dorsal well, and face will be extruded bean curd scoriform material, the back preventing from scar of healing, but Lock-out.
On motherland's medical science, traditional Chinese medical science subordination is the vegetation that occurs in skin surface in the wart class, because of skin lesion position form difference title different.Nothing more than being noxious dampness and insect poison, be the assorted mutually invasion of damp and hot and insect poison, rich tie and superfluous giving birth in skin, or the cause of disease is many and differ, or the heresy of wind heat, stagnate skin and giving birth to, or by affection due to external wind and heat noxious dampness invasion and attack skin, the visitor in body surface then the QI and blood aquatic weeds tie, be condensed into wart or hinder in skin or deficiency of the liver blood dry because of stagnation of QI due to depression of the liver, vim and vigour discord, qi stagnation hemagglutination, in get angry, multiple sense poison is evil, due to the pyretic toxicity stasis of blood knot.Controlling should QI and blood regulating, the wind suppressing the hyperactive liver that looses, heat-clearing and toxic substances removing, the beneficial transconversion into heat stasis of blood, parasite killing are moisturized, movable blood soft hard is main.
Summary of the invention:
Chinese medicine is prevented and cured diseases the history in thousands of years in China, accumulated many success experience prescriptions of preventing and curing diseases, and is the precious legacy rarity of Chinese traditional.The Chinese medicine modernization is exactly on the basis of inheriting and developing China's tradition Chinese medicine advantage and characteristic, make full use of the most high-new modern science of technology theory, state-of-the-art scientific and technical ways and means research, exploitation and to produce with " the most modernized " and up-to-date high-tech be that the modern nanometer Chinese medicine of " safety; efficient; stablize; controlled " of feature is controlled the wart product, core technology of the present invention concretely is exactly the single medicinal material at the various warts of treatment, the element medicine, effectively herbal mixture carries out the processing of nanorize, or in original compound recipe, add the Chinese medicine and the nanometer microelement of nanorize, by changing original route of administration, the drug effect method, site of action, bring into play the incomparable effect of normal shape Chinese medicine, and avoided Chinese medicine and compound recipe thereof loaded down with trivial details treatment process and the complicated Therapeutic Method in processing and therapeutic process.
The curative effect of Chinese medicine had both come from the special chemical component of Chinese medicine, and closely related with medicine metabolic process in vivo again, medicine enters in the body, has experienced absorption, distribution, metabolism and excretory process.As time goes on, the concentration of blood Chinese medicine can reduce gradually, therapeutic effect can weaken gradually, because the physicochemical property of medicine has directly influenced absorbing of Chinese medicine, so the present invention by nanotechnology with the Chinese medicine grain diameter nanoization, change the physical state of its Chinese medicine medicine, improve absorbance and the bioavailability of human body, and increase curative effect the Chinese medicine medicine.Nanometer Chinese medicine has promoted the dissolving of medicine because its big specific surface area has increased the surface area that is exposed in the medium.Because wherein the Chinese medicine diameter of aspirin particle reduces, and has increased medicine distribution in vivo, has improved bioavailability of medicament greatly.General Chinese medicine is before and after concocting, and cell wall is complete, and its effective ingredient has only the stripping of very little a part of penetration cell wall and the utilization that is absorbed by the body.Adopt the Chinese medicine after the nanotechnology processing can make the complete breaking cellular wall of cell wall, make more in pharmaceutically active ingredient be released fully, and the utilization that is absorbed by the body, thus improved the bioavailability and the curative effect of Chinese medicine greatly.
There is very a little bit smaller skin injury just to be easy to be infected as long as suffer from the wart person by human papillomavirus, and suffer from the wart person is because in patient's body and to lack elements such as zinc, copper, ferrum, selenium in the skin relevant, because these several constituent contents of human body skin are the abundantest, in case lack, the immunity of human body just reduces the resistance of disease.Zinc is the most obvious to the influence of immune function of human body; the zinc element amount reduces and may cause that cellular immune function is low in the body; zinc supplement can improve immunologic function; zinc relies on enzyme and participates in and regulate immunologic function; zinc is the activity factor of thymidine kinase and archaeal dna polymerase; be the key substance of synthetic DNA (deoxyribonucleic acid), immunologic function is had specific effect, skin is had important defencive function.Zinc is more active metallic element in the human body, is described as " flower of human life ".Copper is safeguarded normal hemopoietic function and iron metabolism, safeguards the normal function and the scytitis of skeleton and blood vessel and skin.Iron deficiency causes that the human body defence capability reduces, and the leukocyte sterilizing ability reduces, and the prevalence of infectious disease is had increase greatly.Selenium can be brought into play the Detoxication of bacteriostatic pharmacological action and antagonism harmful element, selenium participates in the catalytic reaction of enzyme, increase immunity of organisms, effectively improve the immune level of body, minimizing and elimination are to the inhibition of immunocyte, and scarce selenium makes the human leukocytes immunologic hypofunction, humoral immune reaction reduces, macrophage also reduces, and notices that zinc supplement also is essential so easily suffer from the patient of wart, because it can reduce developing of various warts.
Survive in the liquid that virus can be detained on current consumption product such as phone, when resistance of human body, hypoimmunity, even very little little by little damage just is easy to infect.Various warts promptly are the dermatosiss that a kind of virus causes, especially skin lesion is a kind of discosmetic dermatosis at positions such as face exposure or arms.Treatment by Chinese herbs heat-clearing and toxic substances removing, pesticide and disinfectant, dampness removing dampness remove wart, dehumidifying dampness removing, soft muscle eliminating stagnation, removing heat from blood, blood circulation and promoting silt, removing blood stasis with potent drugs detumescence.The present invention treats the medicine preparation principle of wart class on the effective Chinese medicinal formulae of inheriting tradition basis, adopt the nanotechnology of up-to-date scientific and technological circle hot topic, element balance medical science, to sterilize, kill the virus, pathogenic bacterium microorganism such as fungus has the potent antibacterial action of wide spectrum and antibiotic persistent nanometer silver is aseptic antibacterial, promptly be in inorganic compound, to add antibiotic property ion such as silver are arranged.Be silver-based inorganic antibacterial agent, and metal ion antibacterial agent such as copper, zinc.(available changzhou five Pedicellus et Pericarpium Trapaes, Taixing, Jiangsu nano material company limited are produced nanoscale ZnO powder, sea, river, Taixing City, Jiangsu group production nano-TiO with sluggish precipitation
2Powder does not have the mattress agent).TiO
2Be present modal photocatalyst-type anti-biotic agent, its feature: this material toxicity is low, to people's safety, skin do not had irritates, and antibacterial ability is strong, and has a broad antifungal spectrum has and promptly imitates antibacterial effect.Performance needs and about 24H as the effect of silver-series antibacterial agent.TiO
2The antibacterial action performance only needs about 1h TiO
2The performance of antibacterial action is undertaken by photocatalysis, and it can consume with the prolongation of antibacterial service time gradually unlike other antibacterial.And effect slowly descends.So TiO
2The photocatalyst-type anti-biotic agent has persistent antibacterial effect, and nontoxic, tasteless, non-stimulated, and silver ion is embedded TiO
2Lattice reaches silver no microbial inoculum of system and TiO
2The two combination of photocatalysis antibacterial agent, " the AT antibacterial " of learning from other's strong points to offset one's weaknesses, to escherichia coli, staphylococcus aureus killing rate up to 99.99%." AT antibacterial " produced by the Chenzhou City Jingui Nonferrous Metal Co., Ltd.
The present invention is further described below in conjunction with examples of implementation:
Embodiment one: condyloma acuminatum
Medicine is formed:
(1) Rhizoma Atractylodis, each 12g of Cortex Phellodendri respectively account for 12%; Silver is TA antibacterial 6g, accounts for 6%; Soil Cortex cinnamomi japonici (Ramulus Cinnamomi), hundred steps, Cortex Dictamni, Radix Arnebiae (Radix Lithospermi), Realgar, each 10g of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) respectively account for 10%; Fructus Bruceae, each 5g of Semen Strychni respectively account for 5%.The heavy 94g of medicine.
Method for making: be ground into the nano powder end altogether and hold white furnishing pasty state with the Fel Serpentis skin that Nantong Snakes Treating Inst. produces, adding nanometer silver is the TA antibacterial.
Cure mainly: condyloma acuminatum
(2) Radix Isatidis, living Rhizoma Cyperi, Herba Equiseti Hiemalis, each 250g of Nidus Vespae respectively account for 25%.
Effect: removing damp-heat, the diffusing wart of detoxifcation
Cure mainly: condyloma acuminatum
(3) Rhizoma Coptidis, each 50g of Cortex Phellodendri account for 23.8%; Radix Arnebiae (Radix Lithospermi) 100g accounts for 47.6%; Margarita 10g accounts for 4.8%.Cross 120 mesh sieve g.
Usage: adopt the band wire cotton balls to dip in powder and fill in intravaginal and include in morning, take out evening, and every day 1 time is till wart falls.
Cure mainly: the vagina condyloma acuminatum
(4) Herba Hedyotidis Diffusae, Herba Taraxaci, each 30g of Fructus Cnidii account for 12%; Radix Isatidis, Radix Sophorae Flavescentis, hundred each 20g of step account for 8%; Herba Agrimoniae, Herba Epimedii, each 18g of Rhizoma Smilacis Glabrae respectively account for 7.2%; Herba Schizonepetae, Radix Saposhnikoviae, each 15g of Periostracum Cicadae respectively account for 6%.
The heavy 249g of medicine.
Cure mainly: vulval condyloma acuminatum
(5) Radix Isatidis, Radix Sophorae Flavescentis, each 30g of Folium Isatidis; Herba Equiseti Hiemalis, Rhizoma Atractylodis, Rhizoma Cyperi (processed), each 20g of Flos Carthami.
Cure mainly: condyloma acuminatum of anus
(6) Rhizoma Atractylodis, each 60g of Cortex Phellodendri respectively account for 12.8%; Soil Cortex cinnamomi japonici (Ramulus Cinnamomi), hundred steps, Cortex Dictamni, Radix Arnebiae (Radix Lithospermi), Realgar, each 50g of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) respectively account for 10.6%; Fructus Bruceae, each 25g of Semen Strychni respectively account for 5.3%.The heavy 470g of medicine.
Method for making: the Cheng Jinxue board Fel Serpentis skin that common porphyrize powder is crossed 400 mesh sieves and Nantong Snakes Treating Inst.'s production holds the deposited affected part of white furnishing pasty state.
Cure mainly: condyloma acuminatum
(7) Radix Isatidis, Herba Portulacae, Rhizoma Smilacis Glabrae, Flos Lonicerae, Cortex Phellodendri, Rhizoma Atractylodis, each 50g of Spica Prunellae account for 9%; Radix Glycyrrhizae 20g, 3.6%; Semen Persicae, Flos Carthami, Rhizoma Cyperi, Nidus Vespae, hundred steps, each 30g of Herba Equiseti Hiemalis respectively account for 5.5%.The heavy 550g of medicine.
Method for making: the porphyrize powder is crossed 400 mesh sieves altogether, holds white furnishing pasty state with the Fel Serpentis skin and applies the affected part.
Cure mainly: condyloma acuminatum
Embodiment two: verruca vulgaris
(1) Fructus Mume, Rhizoma et radix veratri (Radix Rhizoma Veratri), Semen Euphorbiae, each 30g of Semen Impatientis soak 75% ethanol 500ml, and be standby after the week.
Effect: the merit of pesticide and disinfectant, the power of wart of disappearing of invigorating blood circulation
Cure mainly: verruca vulgaris
(2) bright Radix Rumicis 500g; Soil Cortex cinnamomi japonici (Ramulus Cinnamomi) 360g; The Fructus Kochiae, Cortex erythrinae, each 120g of Fructus Cnidii; Dragon clothing 12g; Jowar wine 500ml soaks reserve in January and uses.
Cure mainly: verruca vulgaris
(3) living Rhizoma Cyperi, each 500g of Herba Equiseti Hiemalis; Rhizoma Dioscoreae Bulbiferae, each 250g of Herba Solani Nigri; Flos Carthami 100g, 60% ethanol 4000ml soaks a week, gets medicinal liquid.Every 100ml adds dimethyl fork vitriol 30ml.
Cure mainly: verruca vulgaris, verruca plana, foot hundred warts
Embodiment three: verruca plana
(1) Rhizoma Cyperi 500g accounts for 57.1%; Sepiellae seu sepiae 250g accounts for 28.6%; Fructus Xanthii 125g accounts for 14.3%, immerses 70% ethanol and wipes affected part in 15 days.The heavy 875g of medicine.
(2) Flos Carthami 100g accounts for 10%; The Fructus Kochiae, Cortex Dictamni, white each 200g of sail respectively account for 20%; Periostracum Cicadae 300g accounts for 30%, and high 75% ethanol 5000ml soaks.The heavy 1000g of medicine.
Cure mainly: verruca vulgaris
(3) Folium Isatidis, Radix Isatidis, Semen Coicis, each 150g of Cortex Dictamni respectively account for 15.6%; Radix Sophorae Tonkinensis 50g accounts for 5.2%; Herba Equiseti Hiemalis 100g accounts for 10.4%; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Periostracum Cicadae, each 45g of Pericarpium Citri Reticulatae respectively account for 4.7%; Radix Glycyrrhizae 30g accounts for 3.1%.The heavy 960g of medicine.
Cure mainly: verruca vulgaris, verruca plana, foot hundred warts
Embodiment four: infectious warts
Medicine is formed:
(1) Semen Hydnocarpi, fragrant each 25g of Fructus Bruceae; Rhizoma Cyperi, Herba Equiseti Hiemalis, Radix Isatidis, Semen Coicis, Squama Manis, JINCHONG, Radix Sophorae Flavescentis, Rhizoma Atractylodis, each 50g of Nidus Vespae.
Method for making: after Semen Hydnocarpi, Fructus Bruceae, Squama Manis are smashed to pieces all medicines are immersed in 75% ethanol, make ethanol surpass medicine plane 10cm, sealing was soaked 40 days, filtered standbyly, put on the skin 3～4 times/day.
(2) Rhizoma Cyperi, Rhizoma Osmundae, Radix Isatidis, Semen Coicis, each 30g of Radix Angelicae Sinensis respectively account for 4.6%, 75% ethanol 500ml sealing immersion and puncture its body of wart after 15 days, put on the skin 3～4 times/day with medicine-feeding.The heavy 650g of medicine.
Cure mainly: verruca vulgaris
(3) quicklime, Sanguis Draxonis, each 50g of Fructus Bruceae respectively account for 33.3%, and the porphyrize powder pastes the affected part.
(4) Galla Chinensis 50g accounts for 50%; Realgar 20g accounts for 20%; Fructus Mume, withered sail, each 10g of Radix Et Rhizoma Rhei respectively account for 10%, porphyrize powder and the Fel Serpentis frost mixing batter shape affected part of applying ointment or plaster.
Embodiment five: the inorganic organic natural plant kind antibacterial of nano-element silver zinc copper selenium
(1) nanometer selenium 10%
(2) nanometer zinc ZnO photocatalyst-type inorganic antiseptic 15%
(3) nanometer copper Cu ion inorganic antiseptic 5%
(4) Ag-carried nanometer titanium dioxide (TiO
2) (AT) antibacterial 25%
(5) nanometer Al
2O
3Far infrared radiation antibacterial 7%
(6) organic class antibacterial is as ethanol, isopropyl alcohol etc. 20%
(7) natural antimicrobial agent is as chitin and chitosan etc. 8%
(8) day plant class antibacterial is as Radix Artemisia ordosicae, Radix Glycyrrhizae, Semen Podocarpi Macrophylli, Aloe, propolis 10%
Amount to 100%
Embodiment six: a certain prescription of nanometer Chinese medicine and inorganic, organic, the natural plant kind antibacterial of nano-element silver zinc copper selenium
(1) a certain prescription 60% in each prescription of nanometer Chinese medicine
(2) the inorganic organic natural plant kind antibacterial 40% of nano-element silver zinc copper selenium
Amount to 100%.
Claims (6)
1. reinforced nano silver selenium element Chinese medicine is controlled the topical agent of wart class, it is characterized in that: be used for condyloma acuminatum by following several groups of Chinese medicinal formulaes
(1) Rhizoma Atractylodis, each 7～19g of Cortex Phellodendri respectively account for 17～20%; Silver is TA antibacterial 1～11g, accounts for 1～11%; Soil Cortex cinnamomi japonici (Ramulus Cinnamomi), hundred steps, Cortex Dictamni, Radix Arnebiae (Radix Lithospermi), Realgar, each 5～15g of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) respectively account for 5～15%; Fructus Bruceae, each 1～10g of Semen Strychni respectively account for 1～10%.
(2) Radix Isatidis, living Rhizoma Cyperi, Herba Equiseti Hiemalis, each 200～300g of Nidus Vespae respectively account for 15～40%.
(3) Rhizoma Coptidis, each 30～70g of Cortex Phellodendri respectively account for 18～29%; Radix Arnebiae (Radix Lithospermi) 70～130g accounts for 42～52%; Margarita 5～15g accounts for 1～9%.
(4) Herba Hedyotidis Diffusae, Herba Taraxaci, each 20～40g of Fructus Cnidii respectively account for 9～15%; Radix Isatidis, Radix Sophorae Flavescentis, hundred each 10～30g of step respectively account for 3～13%; Herba Agrimoniae, Herba Epimedii, each 10～30g of Rhizoma Smilacis Glabrae respectively account for 5～13%; Herba Schizonepetae, Radix Saposhnikoviae, each 10～20g of Periostracum Cicadae respectively account for 1～11%.
(5) Radix Isatidis, Radix Sophorae Flavescentis, each 20～40g of Folium Isatidis respectively account for 5～12%; Herba Equiseti Hiemalis, Rhizoma Atractylodis, Rhizoma Cyperi (processed), each 10～30g of Flos Carthami respectively account for 5～12%.
(6) Rhizoma Atractylodis, each 50～70g of Cortex Phellodendri respectively account for 7～18%; Soil Cortex cinnamomi japonici (Ramulus Cinnamomi), hundred steps, Cortex Dictamni, Radix Arnebiae (Radix Lithospermi), Realgar, each 40～60g of the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) respectively account for 5～17%; Fructus Bruceae, each 15～40g of Semen Strychni respectively account for 1～10%.
(7) Radix Isatidis, Herba Portulacae, Rhizoma Smilacis Glabrae, Flos Lonicerae, Cortex Phellodendri, Rhizoma Atractylodis, each 40～60g of Spica Prunellae account for 4～14%; Radix Glycyrrhizae 10～30g, 1～6%; Semen Persicae, Flos Carthami, Rhizoma Cyperi, Nidus Vespae, hundred steps, each 20～40g of Herba Equiseti Hiemalis respectively account for 2～9%.
2. according to claims 1, reinforced nano silver selenium element Chinese medicine is controlled the topical agent of wart class, it is characterized in that: be used for verruca vulgaris by following several groups of Chinese medicinal formulaes
(1) Fructus Mume, Rhizoma et radix veratri (Radix Rhizoma Veratri), Semen Euphorbiae, each 20～40g of Semen Impatientis respectively account for 1～9%; 75% ethanol, 400～600ml accounts for 70～86%.
(2) bright Radix Rumicis 400～600g accounts for 20～34%; Soil Cortex cinnamomi japonici (Ramulus Cinnamomi) 300～420g accounts for 1～3%; The Fructus Kochiae, Cortex erythrinae, each 120～140g of Fructus Cnidii account for 1～12%; Dragon clothing 12～14g accounts for 5～19%; Jowar wine 400～600ml accounts for 20～35%.
(3) living Rhizoma Cyperi, each 400～600g of Herba Equiseti Hiemalis respectively account for 3～14%; Rhizoma Dioscoreae Bulbiferae, each 200～300g of Herba Solani Nigri respectively account for 1～9%; Flos Carthami 50～150g accounts for 0.5～2.5%; 60% ethanol, 3500～4500ml accounts for 65～76%.
3. according to claims 1,2, reinforced nano silver selenium element Chinese medicine is controlled the topical agent of wart class, it is characterized in that: be used for verruca plana by following several groups of Chinese medicinal formulaes
(1) Rhizoma Cyperi 450～550g accounts for 50～63%; Sepiellae seu sepiae 200～300g accounts for 23～33%; Fructus Xanthii 100～150g accounts for 9～19%; Immerse 70% ethanol and wiped affected part in 15 days.
(2) Flos Carthami 50～150g accounts for 5～15%; The Fructus Kochiae, Cortex Dictamni, white each 150～250g of sail respectively account for 10～30%; Periostracum Cicadae 250～350g accounts for 20～40%.High 75% ethanol 5000ml soaks.
(3) Folium Isatidis, Radix Isatidis, Semen Coicis, each 100～200g of Cortex Dictamni respectively account for 10～21%; Radix Sophorae Tonkinensis 30～70g accounts for 1～10%; Herba Equiseti Hiemalis 80～120g accounts for 5～15%; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Periostracum Cicadae, each 30～60g of Pericarpium Citri Reticulatae respectively account for 1～9%; Radix Glycyrrhizae 20～40g accounts for 1～5%.
4. according to claims 1,2,3, reinforced nano silver selenium element Chinese medicine is controlled the topical agent of wart class, it is characterized in that: be used for infectious warts by following several groups of Chinese medicinal formulaes
(1) Semen Hydnocarpi, fragrant each the 20～30g of Fructus Bruceae respectively account for 1～10%; Rhizoma Cyperi, Herba Equiseti Hiemalis, Radix Isatidis, Semen Coicis, Squama Manis, JINCHONG, Radix Sophorae Flavescentis, Rhizoma Atractylodis, each 40～60g of Nidus Vespae respectively account for 5～15%.
(2) Rhizoma Cyperi, Rhizoma Osmundae, Radix Isatidis, Semen Coicis, each 10～50g of Radix Angelicae Sinensis respectively account for 10～30%.
(3) quicklime, Sanguis Draxonis, each 20～80g of Fructus Bruceae respectively account for 1～6% powder such as porphyrize such as branch such as grade and paste the affected part.
(4) Galla Chinensis 20～80g accounts for 40～60%; Realgar 10～30g accounts for 10～30%; Fructus Mume, withered sail, each 5～15g of Radix Et Rhizoma Rhei account for 5～15%.
5. according to claims 1,2,3,4, reinforced nano silver selenium element Chinese medicine is controlled the topical agent of wart class, and it is characterized in that: nano-element silver zinc copper selenium is inorganic, organic, natural plant kind antibacterial proportioning %
(1) nanometer selenium 5～15%
(2) nanometer zinc ZnO photocatalyst-type inorganic antiseptic 10～20%
(3) nanometer copper Cu ion inorganic antiseptic 1～10%
(4) Ag-carried nanometer titanium dioxide (TiO
2) ((AT) antibacterial) 20～30%
(5) nanometer Al
2O
3Far infrared radiation antibacterial 2～12%
(6) organic class antibacterial is as ethanol, isopropyl alcohol etc. 15～25%
(7) natural antimicrobial agent is as chitin and chitosan etc. 3～13%
(8) day plant class antibacterial is as Radix Artemisia ordosicae, Radix Glycyrrhizae, Semen Podocarpi Macrophylli, Aloe, propolis 5～15%
Amount to 100%
6. according to claims 1,2,3,4,5, reinforced nano silver selenium element Chinese medicine is controlled the topical agent of wart class, it is characterized in that: a certain prescription of nanometer Chinese medicine and nano-element silver, zinc, copper, selenium, inorganic, organic, natural plant kind antibacterial proportioning %
(1) a certain prescription 50～70% in each prescription of nanometer Chinese medicine
(2) nano-element silver, zinc, copper, selenium, inorganic, organic, natural plant kind antibacterial 30～50%
Amount to 100%.
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| CN2010101896206A CN101961412A (en) | 2010-06-02 | 2010-06-02 | Medicinal preparation for external use for strengthening treatment on verrucas by Chinese traditional medicines comprising nano-silver and selenium elements |
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| CN102078538A (en) * | 2010-12-24 | 2011-06-01 | 秦三海 | Chinese medicine preparation for treating verruca plana |
| CN102380059A (en) * | 2011-10-25 | 2012-03-21 | 王绪友 | Composite traditional Chinese medicine preparation for removing flat warts |
| CN104784389A (en) * | 2015-04-23 | 2015-07-22 | 朱宜彬 | Traditional Chinese medicine aerosol for treating venereal disease |
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| CN105362816A (en) * | 2015-12-06 | 2016-03-02 | 郑州景鸿畜牧科技有限公司 | Traditional Chinese medicinal liquor with rhizoma drynariae |
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| CN102078538A (en) * | 2010-12-24 | 2011-06-01 | 秦三海 | Chinese medicine preparation for treating verruca plana |
| CN102380059A (en) * | 2011-10-25 | 2012-03-21 | 王绪友 | Composite traditional Chinese medicine preparation for removing flat warts |
| CN104784389A (en) * | 2015-04-23 | 2015-07-22 | 朱宜彬 | Traditional Chinese medicine aerosol for treating venereal disease |
| CN105362816A (en) * | 2015-12-06 | 2016-03-02 | 郑州景鸿畜牧科技有限公司 | Traditional Chinese medicinal liquor with rhizoma drynariae |
| CN105286134A (en) * | 2015-12-07 | 2016-02-03 | 刘博纯 | Method for preparing photocatalytic mouth mask |
| CN107082650A (en) * | 2017-03-30 | 2017-08-22 | 合肥金同维低温科技有限公司 | A kind of refrigerator antibacterial insulation material and preparation method |
| EP3620167A4 (en) * | 2018-03-29 | 2020-06-03 | Beijing Patborn Biotechnology Development Co., Ltd | Traditional chinese medicine composition for treating diseases caused by human papillomavirus, preparation method therefor and use thereof |
| US11278583B2 (en) * | 2018-03-29 | 2022-03-22 | Zhuanshe DU | Traditional Chinese medicine composition for treating diseases caused by human papillomavirus, preparation method and use thereof |
| CN112237606A (en) * | 2019-07-17 | 2021-01-19 | 段芝堂(北京)国际医药技术开发有限公司 | Plant essential oil formula for HPV recovery |
| CN115154565A (en) * | 2022-07-27 | 2022-10-11 | 抚顺市新抚区福康皮肤病门诊部 | A Chinese medicinal composition for treating condyloma acuminatum |
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Application publication date: 20110202 |