CN101951768A - 神经原性化合物 - Google Patents

神经原性化合物 Download PDF

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Publication number
CN101951768A
CN101951768A CN200880011384XA CN200880011384A CN101951768A CN 101951768 A CN101951768 A CN 101951768A CN 200880011384X A CN200880011384X A CN 200880011384XA CN 200880011384 A CN200880011384 A CN 200880011384A CN 101951768 A CN101951768 A CN 101951768A
Authority
CN
China
Prior art keywords
sugar
compound
gallate
maltose
fructose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880011384XA
Other languages
English (en)
Chinese (zh)
Inventor
J·F·小哈默斯通
M·A·克尔姆
F·H·盖奇
H·范普拉格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mars Inc
Salk Institute for Biological Studies
Original Assignee
Mars Inc
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mars Inc, Salk Institute for Biological Studies filed Critical Mars Inc
Publication of CN101951768A publication Critical patent/CN101951768A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200880011384XA 2007-02-14 2008-02-13 神经原性化合物 Pending CN101951768A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90123907P 2007-02-14 2007-02-14
US60/901,239 2007-02-14
PCT/US2008/001914 WO2008147483A2 (en) 2007-02-14 2008-02-13 Neurogenic compounds

Publications (1)

Publication Number Publication Date
CN101951768A true CN101951768A (zh) 2011-01-19

Family

ID=39763345

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880011384XA Pending CN101951768A (zh) 2007-02-14 2008-02-13 神经原性化合物

Country Status (9)

Country Link
US (1) US20080227829A1 (https=)
EP (2) EP2117306A4 (https=)
JP (1) JP2010518164A (https=)
CN (1) CN101951768A (https=)
AU (1) AU2008257437A1 (https=)
CA (1) CA2677892A1 (https=)
IL (1) IL200383A0 (https=)
RU (1) RU2009134137A (https=)
WO (1) WO2008147483A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2772614A1 (en) 2009-09-02 2011-03-10 Massachusetts General Hospital Corporation Compounds and compositions for treating cancer
US8318737B2 (en) 2009-09-02 2012-11-27 Canthera Therapeutics Inc. Compounds and compositions for treating cancer
US8349832B2 (en) * 2009-09-02 2013-01-08 Canthera Therapeutics Compounds and compositions for treating cancer
BR112012011336A2 (pt) 2009-10-22 2018-10-16 Api Genesis Llc Composições compreendendo flavonoides, seu método de preparação, adesivo para aplicação de flavonoide, métodos de produção de flavonoide hidratado,métodos de preparação de formulação tópica, e uso de flavonoide
KR101817635B1 (ko) 2010-10-22 2018-01-11 비쭈리 헬스 사이언스 엘엘씨 난용성 화합물의 용해도를 증가시키는 방법과 이와 같은 화합물의 제형을 제조하는 방법 및 사용하는 방법
US9527860B2 (en) 2011-06-17 2016-12-27 Ludwig Aigner Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders
CN104066840B (zh) * 2012-01-17 2016-11-09 三得利控股株式会社 新型糖基转移酶基因及其使用
JP6797408B2 (ja) 2014-11-06 2020-12-09 国立大学法人 長崎大学 新規アルツハイマー病治療薬
JP6207545B2 (ja) * 2015-04-30 2017-10-04 丸大食品株式会社 学習記憶能力増強剤
JP6842093B2 (ja) * 2019-08-20 2021-03-17 丸大食品株式会社 学習記憶能力増強剤
JP7754447B2 (ja) * 2021-10-21 2025-10-15 松本 忠昌 ストレスを軽減するための組成物

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9317071D0 (en) * 1993-08-17 1993-09-29 Univ Strathclyde Flavonoids
GB9521184D0 (en) * 1995-10-17 1995-12-20 Univ Strathclyde Flavonoids
US6297273B1 (en) * 1996-04-02 2001-10-02 Mars, Inc. Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions
US5733926A (en) * 1996-12-13 1998-03-31 Gorbach; Sherwood L. Isoflavonoids for treatment and prevention of alzheimer dementia and reduced cognitive functions
US5952374A (en) * 1997-09-29 1999-09-14 Protein Technologies International, Inc. Method for inhibiting the development of Alzheimer's disease and related dementias- and for preserving cognitive function
ATE264093T1 (de) * 1998-07-16 2004-04-15 Aaron Tabor Sojazubereitungen und deren verwendung zur gesundheitsförderung
KR20010079922A (ko) * 1998-09-24 2001-08-22 미우라 아키라 하이드록시플라본 유도체
US6451837B1 (en) * 1999-09-01 2002-09-17 Andrius Baskys Neuroprotective effects of mitogen-activated protein kinase (MAPK) cascade inhibitors
US20010047032A1 (en) * 1999-12-30 2001-11-29 Castillo Gerardo M. Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases
EP1127572A3 (en) * 2000-02-25 2003-05-02 Basf Aktiengesellschaft Use of flavones for treating cycloxygenase-2 mediated diseases
GB2348371B (en) * 2000-03-14 2001-04-04 Soares Da Silva Patricio Compositions comprising blockers of L-DOPA renal cell transfer for the treatment of Parkinson's disease
US6472436B1 (en) * 2000-07-17 2002-10-29 The Salk Institute For Biological Studies Methods for protecting cells from amyloid toxicity and for inhibiting amyloid protein production
JP4633897B2 (ja) * 2000-08-17 2011-02-16 長瀬産業株式会社 神経突起伸長剤
US6733797B1 (en) * 2000-11-15 2004-05-11 William K. Summers Neuroceutical for improving memory and cognitive abilities
WO2002076473A1 (en) * 2001-03-26 2002-10-03 Academy Of Military Medical Sciences Institute Of Pharmacology And Toxicology Quercetin derivative and its medicinal use
CA2493888C (en) * 2001-07-27 2013-07-16 Neptune Technologies & Bioressources Inc. Natural marine source phospholipids comprising flavonoids, polyunsaturated fatty acids and their applications
JP4609875B2 (ja) * 2001-07-31 2011-01-12 有限会社大長企画 健康食品
EP1545206B1 (en) * 2002-07-24 2020-03-04 Children's Hospital Medical Center Compositions and products containing enantiomeric equol, and methods for their making
US8138165B2 (en) * 2002-10-22 2012-03-20 Jenken Biosciences, Inc. Chromones and chromone derivatives and uses thereof
US7763588B2 (en) * 2003-06-13 2010-07-27 The Salk Institute For Biological Studies Method for increasing cognitive function and neurogenesis
WO2005020881A2 (en) * 2003-09-01 2005-03-10 Shanghai Comman Pharmaceutical Co. Compositions of flavonoids and flavonoid-containing extracts and the treatment of diseases
KR100610562B1 (ko) * 2004-06-28 2006-08-08 재단법인서울대학교산학협력재단 플라보노이드 유도체를 포함하는 급성 또는 만성 퇴행성뇌질환의 예방 또는 치료용 조성물
US20060148727A1 (en) * 2004-12-01 2006-07-06 Curt Hendrix Folate based composition for neurological and cognitive applications
US7442394B2 (en) * 2005-05-02 2008-10-28 University Of South Florida Combined effects of nutrients on proliferation of stem cells
WO2008011538A2 (en) * 2006-07-19 2008-01-24 The Salk Institute For Biological Studies Methods of using flavonoids to enhance memory

Also Published As

Publication number Publication date
JP2010518164A (ja) 2010-05-27
EP2117306A4 (en) 2010-02-10
EP2478901A3 (en) 2012-11-14
RU2009134137A (ru) 2011-03-27
US20080227829A1 (en) 2008-09-18
AU2008257437A1 (en) 2008-12-04
WO2008147483A8 (en) 2009-01-15
EP2117306A2 (en) 2009-11-18
WO2008147483A3 (en) 2009-02-26
CA2677892A1 (en) 2008-12-04
EP2478901A2 (en) 2012-07-25
WO2008147483A2 (en) 2008-12-04
WO2008147483A9 (en) 2009-04-09
IL200383A0 (en) 2010-04-29

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SE01 Entry into force of request for substantive examination
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Application publication date: 20110119