CN101932353B - 毛细管气雾剂产生器的分配方法和系统 - Google Patents

毛细管气雾剂产生器的分配方法和系统 Download PDF

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Publication number
CN101932353B
CN101932353B CN200880110018XA CN200880110018A CN101932353B CN 101932353 B CN101932353 B CN 101932353B CN 200880110018X A CN200880110018X A CN 200880110018XA CN 200880110018 A CN200880110018 A CN 200880110018A CN 101932353 B CN101932353 B CN 101932353B
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CN
China
Prior art keywords
flow rate
capillary
flow
liquid formulation
aerosol generating
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Application number
CN200880110018XA
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English (en)
Chinese (zh)
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CN101932353A (zh
Inventor
N·马哈拉杰
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Philip Morris Products SA
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Philip Morris Products SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A61M15/025—Bubble jet droplet ejection devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B15/00—Details of spraying plant or spraying apparatus not otherwise provided for; Accessories
    • B05B15/50—Arrangements for cleaning; Arrangements for preventing deposits, drying-out or blockage; Arrangements for detecting improper discharge caused by the presence of foreign matter
    • B05B15/52—Arrangements for cleaning; Arrangements for preventing deposits, drying-out or blockage; Arrangements for detecting improper discharge caused by the presence of foreign matter for removal of clogging particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
    • B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
    • B08B9/027—Cleaning the internal surfaces; Removal of blockages
    • B08B9/032—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
    • B08B9/0321—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing using pressurised, pulsating or purging fluid
    • B08B9/0326—Using pulsations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0402—Cleaning, repairing, or assembling
    • Y10T137/0419—Fluid cleaning or flushing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Emergency Medicine (AREA)
  • Nozzles (AREA)
  • Spray Control Apparatus (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Medicinal Preparation (AREA)
CN200880110018XA 2007-10-02 2008-10-01 毛细管气雾剂产生器的分配方法和系统 Active CN101932353B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97699107P 2007-10-02 2007-10-02
US60/976,991 2007-10-02
PCT/IB2008/003256 WO2009044280A2 (en) 2007-10-02 2008-10-01 Dispensing method and system of a capillary aerosol generator

Publications (2)

Publication Number Publication Date
CN101932353A CN101932353A (zh) 2010-12-29
CN101932353B true CN101932353B (zh) 2013-07-03

Family

ID=40348133

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880110018XA Active CN101932353B (zh) 2007-10-02 2008-10-01 毛细管气雾剂产生器的分配方法和系统

Country Status (14)

Country Link
US (2) US20090084865A1 (enExample)
EP (1) EP2211955B1 (enExample)
JP (1) JP5205463B2 (enExample)
KR (1) KR101533471B1 (enExample)
CN (1) CN101932353B (enExample)
AU (1) AU2008306583A1 (enExample)
BR (1) BRPI0817649B8 (enExample)
CA (1) CA2701389C (enExample)
ES (1) ES2623906T3 (enExample)
HU (1) HUE032676T2 (enExample)
MX (1) MX2010003494A (enExample)
PL (1) PL2211955T3 (enExample)
PT (1) PT2211955T (enExample)
WO (1) WO2009044280A2 (enExample)

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IL298116A (en) 2010-12-22 2023-01-01 Syqe Medical Ltd Method and system for drug delivery
PL2925395T3 (pl) 2012-11-28 2019-08-30 Fontem Holdings 1 B.V. Urządzenie wytwarzające aerozol kondensacyjny z ciekłej formulacji
CN109954607B (zh) * 2013-07-19 2021-10-26 固瑞克明尼苏达有限公司 用于喷涂系统的泵转换算法
JP6408573B2 (ja) * 2013-07-19 2018-10-17 グラコ ミネソタ インコーポレーテッド スプレーシステム用ポンプの作動切換装置及び方法
WO2015042412A1 (en) 2013-09-20 2015-03-26 E-Nicotine Technology. Inc. Devices and methods for modifying delivery devices
FR3019442A1 (fr) * 2014-04-04 2015-10-09 Agece Ecole Centrale D Electronique Dispositif d'ajustement d'une quantite de nicotine inhalee par un utilisateur et terminal portable communiquant
CN106659858B (zh) 2014-06-30 2020-11-24 Syqe医药有限公司 用于吸入器装置的药物剂量盒
RU2690401C2 (ru) 2014-06-30 2019-06-03 Сике Медикал Лтд. Способ и устройство для испарения и ингаляции выделенных веществ
RU2691615C2 (ru) * 2014-06-30 2019-06-14 Сике Медикал Лтд. Ингалятор с регулированием потока
US10118006B2 (en) 2014-06-30 2018-11-06 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
US11806331B2 (en) 2016-01-06 2023-11-07 Syqe Medical Ltd. Low dose therapeutic treatment
WO2019018436A1 (en) * 2017-07-17 2019-01-24 Desktop Metal, Inc. ADDITIVE MANUFACTURING USING VARIABLE BUILDING MATERIAL FEED RATES
EP3723912B1 (en) * 2017-12-14 2022-08-24 Stamford Devices Limited Mounting of an aerosol generator aperture plate to a support
IT201800006391A1 (it) * 2018-06-18 2019-12-18 Sistema per la vaporizzazione molecolare di una sostanza liquida
US10897925B2 (en) 2018-07-27 2021-01-26 Joseph Pandolfino Articles and formulations for smoking products and vaporizers
US20200035118A1 (en) 2018-07-27 2020-01-30 Joseph Pandolfino Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes
WO2020089890A1 (en) 2018-10-28 2020-05-07 Syqe Medical Ltd. Cartridge unit coupler

Citations (4)

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US3450092A (en) * 1965-07-08 1969-06-17 Vilbiss Co The De Color change apparatus
US5526962A (en) * 1993-05-10 1996-06-18 Medimpex Ets. Double piston pump for administering medication
CN1222089A (zh) * 1996-05-15 1999-07-07 菲利普莫里斯生产公司 气溶胶和制备气溶胶的方法和设备
EP1066850A1 (en) * 1999-07-08 2001-01-10 Siemens-Elema AB Medical Nebulizer

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US4960992A (en) * 1983-08-30 1990-10-02 Research Corporation Technologies Method and means for vaporizing liquids by means of heating a sample capillary tube for detection or analysis
US4575609A (en) * 1984-03-06 1986-03-11 The United States Of America As Represented By The United States Department Of Energy Concentric micro-nebulizer for direct sample insertion
JP3042978B2 (ja) * 1996-03-25 2000-05-22 エムケー精工株式会社 洗車機
US6792940B2 (en) * 1996-05-13 2004-09-21 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US6003512A (en) * 1997-11-13 1999-12-21 Lovelace Respiratory Research Institute Dust gun-aerosol generator and generation
US6276347B1 (en) * 1998-09-25 2001-08-21 Micro Coating Technologies, Inc. Systems and methods for delivering atomized fluids
US6501052B2 (en) * 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6640050B2 (en) * 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US7004407B2 (en) * 2001-12-04 2006-02-28 Mystic Tan, Inc. Uniform metering system for spray applications
US6804458B2 (en) * 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
PT1549440E (pt) * 2002-09-06 2013-01-25 Philip Morris Usa Inc Dispositivo de geração de aerossóis e seu método de utilização
US6772757B2 (en) * 2002-10-25 2004-08-10 Chrysalis Technologies Incorporated Concentric controlled temperature profile fluid vaporizing device
US20040223918A1 (en) * 2003-05-07 2004-11-11 Chrysalis Technologies Incorporated Aerosolization of cromolyn sodium using a capillary aerosol generator
HUE026152T2 (en) * 2004-04-23 2016-05-30 Philip Morris Products Sa Aerosol Generator and Method for Aerosol Production
US7167776B2 (en) * 2004-09-02 2007-01-23 Philip Morris Usa Inc. Method and system for controlling a vapor generator
US7674671B2 (en) * 2004-12-13 2010-03-09 Optomec Design Company Aerodynamic jetting of aerosolized fluids for fabrication of passive structures
KR101413124B1 (ko) * 2006-10-02 2014-07-01 필립모리스 프로덕츠 에스.에이. 연속적인 고압 전달 시스템

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450092A (en) * 1965-07-08 1969-06-17 Vilbiss Co The De Color change apparatus
US5526962A (en) * 1993-05-10 1996-06-18 Medimpex Ets. Double piston pump for administering medication
CN1222089A (zh) * 1996-05-15 1999-07-07 菲利普莫里斯生产公司 气溶胶和制备气溶胶的方法和设备
EP1066850A1 (en) * 1999-07-08 2001-01-10 Siemens-Elema AB Medical Nebulizer

Also Published As

Publication number Publication date
ES2623906T3 (es) 2017-07-12
US20150182707A1 (en) 2015-07-02
AU2008306583A1 (en) 2009-04-09
KR101533471B1 (ko) 2015-07-02
WO2009044280A3 (en) 2009-07-09
JP5205463B2 (ja) 2013-06-05
BRPI0817649B1 (pt) 2020-02-11
BRPI0817649B8 (pt) 2021-06-22
MX2010003494A (es) 2010-06-09
KR20100080823A (ko) 2010-07-12
PT2211955T (pt) 2017-06-29
HUE032676T2 (en) 2017-10-30
WO2009044280A2 (en) 2009-04-09
CN101932353A (zh) 2010-12-29
US20090084865A1 (en) 2009-04-02
BRPI0817649A2 (pt) 2017-05-16
JP2010540149A (ja) 2010-12-24
EP2211955A2 (en) 2010-08-04
CA2701389A1 (en) 2009-04-09
EP2211955B1 (en) 2017-04-12
CA2701389C (en) 2015-12-15
PL2211955T3 (pl) 2017-08-31

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