CN101926926B - Traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis - Google Patents
Traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis Download PDFInfo
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- CN101926926B CN101926926B CN2010102837652A CN201010283765A CN101926926B CN 101926926 B CN101926926 B CN 101926926B CN 2010102837652 A CN2010102837652 A CN 2010102837652A CN 201010283765 A CN201010283765 A CN 201010283765A CN 101926926 B CN101926926 B CN 101926926B
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis, which is prepared from the following traditional Chinese medicines in part by weight: 50 to 80 parts of rhizoma heterosmilacis japonicae and 30 to 60 parts of raw rehmannia root. The traditional Chinese medicinal preparation may be formed into particles, capsules and tablets; and a dose of 13g is taken each time. When the traditional Chinese medicinal preparation is used for treating rheumatic arthritis and chronic infectious arthritis, an obvious effect is produced after administration, joint pain is relieved, join swelling is eliminated, the joint function is restored and improved, the effectiveness is over 98 percent, and the curing rate is over 78 percent. The formula has only two traditional Chinese medicines, so the preparation is simple and the price is low.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation of treating rheumatic arthritis or rheumatoid arthritis.
Background technology
Rheumatic arthritis or rheumatoid arthritis are a kind of frequently-occurring disease commonly encountered diseases, and doctor trained in Western medicine is used medicines such as glucocorticoids, immunosuppressant at present, and therapeutic effect is undesirable; And toxic side effect can not life-time service.Chinese medicine has certain curative effect for the treatment of rheumatic arthritis or rheumatoid arthritis, but decocts trouble, and the patient is difficult to adhere to.CN200510011961.3, a kind of Chinese medicine composition of treating rheumatic or rheumatoid arthritis or gout, its contained effective ingredient is to be processed by the following weight proportion raw material: Rhizoma Atractylodis 5-15 part, raw pearl barley 10-30 part, Pheretima 5-15 part, Radix Stephaniae Tetrandrae 7-22 part, Cortex Phellodendri 5-15 part, Rhizoma Dioscoreae Hypoglaucae 7-22 part, Caulis Lonicerae 10-30 part, windproof 5-15 part, Fructus Forsythiae 7-22 part, Radix Clematidis 6-18 part, Radix Cyathulae 7-22 part, Ramulus Mori 10-30 part.The coarse powder of above-mentioned raw material of Chinese medicine is minced or prepared slices of Chinese crude drugs decocting together, filter, obtain the water extract of above-mentioned raw materials; Or make the alcohol extract of above-mentioned raw materials with decoction and alcohol sedimentation technique, can be made into various dosage forms again.This prescription drug component is more, and price is higher.
Summary of the invention
The object of the present invention is to provide the instant tea of another kind of treatment rheumatic arthritis or rheumatoid arthritis, to realize determined curative effect, simple, lower, the taking convenience of price of component.
Medicine of the present invention is to be processed by the Chinese medicine of following weight ratio: hargil Poria 50-80, Radix Rehmanniae 30-60.
Method for preparing may further comprise the steps:
(1) the hargil Poria with formula ratio adds 6 ~ 10 times of water gagings decoctions 2 hours, decocts secondary altogether, and decocting liquid filters; Secondary filtrating is merged, and heating is concentrated into every ml and is equivalent to crude drug 2g, adds ethanol; Make pure content reach 75%, left standstill 10-15 hour, filter; Reclaim ethanol, get Rhizoma Smilacis Glabrae water decoction-alcohol sedimentation thing; Pure hypostasis vacuum drying is ground into the extractum fine powder, subsequent use;
(2) Radix Rehmanniae is added 6 ~ 10 times of water gagings and decocted 1 hour, decoct secondary altogether; Decocting liquid filters, and secondary filtrating is merged, and the relative density when heating is concentrated into 50 ℃ is 1.30 ~ 1.35 clear paste;
(3) with hargil Poria extract powder, Radix Rehmanniae clear paste, maltodextrin or starch are processed various dosage forms in 3: 2.5: 1～2 ratio mixings according to conventional method.
Said various dosage form comprises granule, capsule, tablet, takes 13g at every turn.
Prescription divides folding: the hargil Poria among the present invention has the detoxifcation dehumidifying, and easing joint movement is used for bones and muscles pain, damp and hot stranguria with turbid discharge, carbuncle Jie Xian.The Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Be used for the consumption of YIN caused by febrile disease tongue and fall excessive thirst, fever due to yin deficiency, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst.Two medicines are also used tool detoxifcation dehumidifying altogether, clearing away heat and cooling blood, and easing joint movement, effects such as wind dehumidifying are gone in bone and muscle strengthening; Thereby rheumatic arthritis or rheumatoid arthritis had therapeutic effect.
The present invention is used to treat rheumatic arthritis or rheumatoid arthritis, and positive effect is all arranged after taking, and has arthralgia and alleviates, and arthroncus is disappeared, the combined effect that the joint functional recovery takes a turn for the better; Reach 95% for the rheumatic arthritis cure rate, effective percentage is 100%; For the rheumatoid arthritis effective percentage is 97%, has only two flavor Chinese medicines in the prescription, and preparation is simple, price is lower.
The specific embodiment
Below in conjunction with embodiment the present invention is described further.
Embodiment 1:
(1) with hargil Poria 70 gram decocte with water secondaries, each 6 ~ 10 times of water gagings, each 2 hours, decocting liquid filtered; The filtrating secondary merges, and heating is concentrated into every ml and is equivalent to crude drug 2g, adds ethanol, makes pure content reach 75%; Left standstill 10 hours, and filtered, reclaim ethanol, get Rhizoma Smilacis Glabrae water decoction-alcohol sedimentation thing; Pure hypostasis vacuum drying is ground into the extractum fine powder, subsequent use;
(2) with Radix Rehmanniae 50 grams, add 8 ~ 6 times of water gagings, decoct secondary, each 1 hour, decocting liquid filtered, and filtrating merges, and the relative density when being concentrated into 50 ℃ is 1.30 ~ 1.35 clear paste;
(3) with hargil Poria extract powder, Radix Rehmanniae clear paste, maltodextrin is processed granulated quickly dissolving pastille 13g in 3: 2.5: 2 ratio mixings according to conventional method.
Usage: one bag of granulated quickly dissolving is poured in the cup, added 150ml hot water and directly reconstitute, for tea-drinking.Every day 2 ~ 3 times.
Clinical observation: examination treating rheumatic arthritis 117 examples, 114 examples will be taken medicine afternoon to 3 day, and 3 examples are in taking medicine back 6 days, and arthralgia alleviates, and arthroncus begins to disappear, and the joint function begins to recover then, and erythema nodosa disappears, and body temperature gradually falls.After the treatment of 2 ~ 7 weeks, 111 examples are cured 6 routine marked improvements.To rheumatoid arthritis 99 examples, treatment back marked improvement 87, progressive 9 examples, no obvious curative effects 3 examples.Most arthroncus begins to disappear in 4 ~ 20 all intrinsic articulation pain reliefs, and disorder of limb ' s activity takes a turn for the better; Though the arthroncus of minority case is disappeared rapidly, pain relief is slower.
Embodiment 2:
(1) with hargil Poria 80 gram decocte with water secondaries, add 8 ~ 10 times of amounts of water, each 2 hours, decocting liquid filtered; The filtrating secondary merges, and heating is concentrated into every ml and is equivalent to crude drug 2g, adds ethanol, makes pure content reach 75%; Left standstill 12 hours, and filtered, reclaim ethanol, get Rhizoma Smilacis Glabrae water decoction-alcohol sedimentation thing; Pure hypostasis vacuum drying is ground into the extractum fine powder, subsequent use;
(2) with Radix Rehmanniae 40 gram decocte with water secondaries, add 6 ~ 8 times of amounts of water, each 1 hour, decocting liquid filtered, and filtrating merges, and the relative density when being concentrated into 50 ℃ is 1.30 ~ 1.35 clear paste;
(3) with hargil Poria extract powder, Radix Rehmanniae clear paste, starch, 3: 2.5: 1 ratio mixings are processed capsule according to conventional method, every 0.15g.
Embodiment 3:
(1) with hargil Poria 75 gram decocte with water secondaries, add 8 ~ 10 times of amounts of water, each 2 hours, decocting liquid filtered; The filtrating secondary merges, and heating is concentrated into every ml and is equivalent to crude drug 2g, adds ethanol, makes pure content reach 75%; Left standstill 12 hours, and filtered, reclaim ethanol, get Rhizoma Smilacis Glabrae water decoction-alcohol sedimentation thing; Pure hypostasis vacuum drying is ground into the extractum fine powder, subsequent use;
(2) with Radix Rehmanniae 55 gram decocte with water secondaries, add 6 ~ 8 times of amounts of water, each 1 hour, decocting liquid filtered, and filtrating merges, and the relative density when being concentrated into 50 ℃ is 1.30 ~ 1.35 clear paste;
(3) with hargil Poria extract powder, clear paste, dextrin is processed tablet in 3: 2.5: 1 ratio mixings according to conventional method, every heavy 0.5g.
Claims (2)
1. a Chinese medicine preparation of treating rheumatic arthritis or rheumatoid arthritis is characterized in that, is processed by the Chinese medicine of following weight ratio: hargil Poria 50-80, Radix Rehmanniae 30-60.
2. the method for preparing of the Chinese medicine preparation of said treatment rheumatic arthritis of claim 1 or rheumatoid arthritis is characterized in that, may further comprise the steps:
(1) the hargil Poria with formula ratio adds 6 ~ 10 times of water gagings decoctions 2 hours, decocts secondary altogether, and decocting liquid filters; Secondary filtrating is merged, and heating is concentrated into every ml and is equivalent to crude drug 2g, adds ethanol; Make pure content reach 75%, left standstill 10-15 hour, filter; Reclaim ethanol, get hargil Poria water decoction-alcohol sedimentation thing; Pure hypostasis vacuum drying is ground into the extractum fine powder, subsequent use;
(2) Radix Rehmanniae is added 6 ~ 10 times of water gagings and decocted 1 hour, decoct secondary altogether; Decocting liquid filters, and secondary filtrating is merged, and the relative density when heating is concentrated into 50 ℃ is 1.30 ~ 1.35 clear paste;
(3) with hargil Poria extract powder, Radix Rehmanniae clear paste, maltodextrin or starch are processed various dosage forms in 3: 2.5: 1～2 ratio mixings according to conventional method.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102837652A CN101926926B (en) | 2010-09-17 | 2010-09-17 | Traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102837652A CN101926926B (en) | 2010-09-17 | 2010-09-17 | Traditional Chinese medicinal preparation for treating rheumatic arthritis and chronic infectious arthritis |
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| CN101926926A CN101926926A (en) | 2010-12-29 |
| CN101926926B true CN101926926B (en) | 2012-07-04 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105535752A (en) * | 2016-01-15 | 2016-05-04 | 吕富冉 | Chinese herb preparation for treating rheumatoid arthritis and nursing method |
| CN107233379A (en) * | 2017-06-27 | 2017-10-10 | 广州智润生物制药科技有限公司 | It is a kind of to treat Chinese medicine preparation of rheumatic arthritis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175441A (en) * | 1997-07-10 | 1998-03-11 | 迟经惠 | Medicine for releasing wind-heat toxin in blood |
| CN1557395A (en) * | 2004-01-19 | 2004-12-29 | 南京中医药大学 | Collateral channels clearing arthralgia dredging prescription for treating rheumatoid arthritis and its preparing process |
| CN101703708A (en) * | 2009-11-10 | 2010-05-12 | 卢速江 | Chinese medicinal preparation for treating rheumatoid arthritis and gout, and preparation method thereof |
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2010
- 2010-09-17 CN CN2010102837652A patent/CN101926926B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175441A (en) * | 1997-07-10 | 1998-03-11 | 迟经惠 | Medicine for releasing wind-heat toxin in blood |
| CN1557395A (en) * | 2004-01-19 | 2004-12-29 | 南京中医药大学 | Collateral channels clearing arthralgia dredging prescription for treating rheumatoid arthritis and its preparing process |
| CN101703708A (en) * | 2009-11-10 | 2010-05-12 | 卢速江 | Chinese medicinal preparation for treating rheumatoid arthritis and gout, and preparation method thereof |
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| CN101926926A (en) | 2010-12-29 |
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Owner name: HU'NAN XIANGQUAN PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: HUNAN XIANGQUAN PHARMACEUTICAL CO., LTD. |
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Address after: 416000 Ya Creek science and Technology Industrial Zone, Hunan, Jishou Patentee after: HUNAN XIANGQUAN PHARMACEUTICAL CO., LTD. Address before: 416000, Hunan, Xiangxi Tujia and Miao Autonomous Prefecture of Jishou Ya Creek science and Technology Industrial Park Patentee before: Hunan Xiangquan Pharmaceutical Co., Ltd. |