CN102335379A - Traditional Chinese preparation for relieving alcoholism and protecting livers - Google Patents
Traditional Chinese preparation for relieving alcoholism and protecting livers Download PDFInfo
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- CN102335379A CN102335379A CN2010102308199A CN201010230819A CN102335379A CN 102335379 A CN102335379 A CN 102335379A CN 2010102308199 A CN2010102308199 A CN 2010102308199A CN 201010230819 A CN201010230819 A CN 201010230819A CN 102335379 A CN102335379 A CN 102335379A
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Abstract
The invention discloses a traditional Chinese preparation for relieving alcoholism and protecting livers. The traditional Chinese preparation is prepared from radix puerariae, hoveniae semoveniae semen, dark plum, chrysanthemum, dried orange peel, hawthorn, rhizoma polygonati, shizandra berry, gynostemma pentaphylla, caulis bambusae in taenian, tsaoko cardamom, salvia miltiorrhiza, oil orange, mulberry leaf, cassia seed, sea backthern, liquorice, jujube, galangal, medlar, ginseng flower, mint, spiceleaf and stevia rebaudiana bertoni. The traditional Chinese preparation can be prepared into tea, granules, oral liquid, tablets and the like. The traditional Chinese preparation has the significant effects of relieving alcoholism and protecting livers, and is an ideal preparation for health-care treatment of excessive drinking, alcoholic liver and fatty liver.
Description
The present invention a kind ofly specializes in insobriety, alcoholic liver, Patients with Fatty Liver health care and treats the preparation that combines.It is a raw material with Chinese medicine, can be made into medicinal tea, oral liquid, electuary, tablet etc.
Alcoholic liver is because a kind of hepatopathy that long-term excessive consumption of alcohol causes.In recent years, alcoholic liver has seriously endangered the healthy of people.Long-term excessive consumption of alcohol, the number of degrees of especially drinking are too high, excessively will make hepatocyte that degeneration, the necrosis of being inflamed property and fibrosis take place, and finally cause liver cirrhosis, and development have been to be difficult to reverse to the infringement of liver so far.If the not in addition treatment of science, the development of disease controlling so just develops into hepatocarcinoma probably.
China has 1,500 ten thousand chronic hepatitis patients approximately, and the ratio that its chronic hepatitis merges fatty liver is 86.2%.And the obese fatty liver number of the infected is more, and 50% obesity merging fatty liver is arranged approximately.Fatty liver is the key factor that causes liver cirrhosis.It is significant to the prevention liver cirrhosis to eliminate fatty liver.But still lack to fatty liver health care and the significant Chinese medicine preparation of therapeutic effect at present.
The present invention is on clinical practice basis for many years, constantly sums up to improve and improves the desirable preparation that is developed into.Through clinical observation, in conjunction with patient's actual needs, for executing the means of controlling, effective percentage reaches 100% with medicated tea etc.
Medicine of the present invention is made up of Radix Puerariae, Semen Hoveniae (Fructus Hoveniae), Fructus Mume, Flos Chrysanthemi, Pericarpium Citri Reticulatae, Fructus Crataegi, Rhizoma Polygonati, Fructus Schisandrae Chinensis, Herb Gynostemmae Pentaphylli, Caulis Bambusae In Taenia, Fructus Tsaoko, Radix Salviae Miltiorrhizae, Fructus Phyllanthi, Folium Mori, Semen Cassiae, Fructus Hippophae, Radix Glycyrrhizae, Fructus Jujubae, Rhizoma Alpiniae Officinarum, Fructus Lycii, Flos Ginseng, Herba Menthae, Herba Pelargonii Graveolentis, Folium Stevlae Rebaudianae.
Medicine compositing range of the present invention is: root of kudzu vine 9-15 gram hoveniae semoveniae semen 9-12 gram dark plum 6-12 gram chrysanthemum 4.5-9 gram dried orange peel 3-9 Keshan short, bristly hair or beard 9-12 gram sealwort 9-15 gram fruit of Chinese magnoliavine 1.5-6 gram caulis bambusae in taenian 4.5-9 gram gynostemma pentaphylla 3-6 gram tsaoko 3-6 gram red sage root 9-15 gram emblic 3-9 gram mulberry leaf 4.5-9 gram cassia seed 9-15 gram sea-buckthorn 3-9 gram Radix Glycyrrhizae 3-9 gram date 6-15 gram galangal 3-9 gram fruit of Chinese wolfberry 6-12 gram flower of Panax ginseng 1.5-9 gram peppermint 3-6 gram spiceleaf 1-3 gram STEVIA REBAUDIANA 3-9 gram.
The present invention's each component weight proportion of filling a prescription is: Radix Puerariae 9% Semen Hoveniae (Fructus Hoveniae) 6% Fructus Mume 6% Flos Chrysanthemi 3% Pericarpium Citri Reticulatae 3% Fructus Crataegi 6% Rhizoma Polygonati 9% Fructus Schisandrae Chinensis 4% Herb Gynostemmae Pentaphylli 3% Caulis Bambusae In Taenia 2% Fructus Tsaoko 2% Radix Salviae Miltiorrhizae 2% Fructus Phyllanthi 3% Folium Mori 4.5% Semen Cassiae 9% Fructus Hippophae 3% Radix Glycyrrhizae 3% Fructus Jujubae 6% Rhizoma Alpiniae Officinarum 3% Fructus Lycii 6% Flos Ginseng 1.5% Herba Menthae 3% Herba Pelargonii Graveolentis 2% Folium Stevlae Rebaudianae 1%.
The processing technique of medicine medicinal tea of the present invention is:
The medicine of formula ratio is chosen decontamination, oven dry, pulverizing, mixing sieve, in the sterilising filtration tea bag of packing into, seal promptly and get.Have on the tea bag to lead and carry short-term.
Medicine of the present invention can also be processed conventional pharmaceutical dosage form except can making above-mentioned medicinal tea, like electuary, and oral liquid, tablet, capsule etc.
The preparation technology of electuary of the present invention is:
By above-mentioned formula ratio, Chinese herbal medicine is chosen decontamination, mixed powder is broken into coarse powder (5-10 order), puts into extraction pot; The water that adds 3 times of amounts of crude drug weight boils back slow fire and boiled one hour again, leaches medicinal liquid; And then the water of adding Chinese herbal medicine weight qdx, boil back slow fire and boil half an hour again, leach medicinal liquid; With front and back secondary combining medicine, the cooling back adds 1-2 and doubly measures fully mixing placement of ethanol (concentration 99%), deposition.Get its supernatant after 20 hours, precipitate is cleaned with a small amount of 50-60% ethanol, and washing liquid merges with filtrating; Decompression recycling ethanol, wait be concentrated to finite concentration after, again the cooling left standstill 12 hours; Make thorough deposition; Filter, low-temperature evaporation to the thick paste shape of will filtrate is subsequent use, and the ratio of the thick paste side (80-90C) of reheating is 1.30-1.35.Wear into fine powder with crystallization of sucrose, it is subsequent use to cross the 80-100 mesh sieve, and it is subsequent use to get commercially available dextrin, and Chinese herb medicine thick paste, Icing Sugar, dextrin are got finished product by 1: 3: 1 weight ratio stirring and evenly mixing.
The preparation technology of oral liquid of the present invention is:
According to preparation identical prepared Chinese herbal medicine thick paste during electuary, thick paste use an amount of distilled water diluting, filter, it is 20% that diluent contains the crude drug amount, the adding simple syrup, potassium sorbate makes the oral liquid finished product.
The present invention uses bonded theory in Chinese and Western and method to realize the name of disease of alcohol-free liver, fatty liver in the Chinese medicine.But its performance belongs to " long-pending disease " " feeling of fullness " " costalgia " disease scopes such as " accumulation of phlegm in the hypochondrium " mostly, and is relevant with stagnation of liver-QI, phlegm-damp.We are at the prescription in principle without prejudice to traditional Chinese medical science eighteen incompatible medicaments nineteen medicaments of mutual restraint, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.
Typical case:
What XX woman suffered from fatty liver 3 years in 28 years old, and the glutamate pyruvate transaminase recurrent fluctuations is about 100u, repeatly through Chinese and western medical treatment, unsatisfactory curative effect.Sb.'s illness took a favorable turn after two months after only obey this tea, and the transaminase is normal, and clothes tea clinical symptom disappearance after half a year regains one's strength, can operate as normal.With nothing recurrence in anti-3 years.
34 years old Marketing Manager of Lee X man is on the drink in response to reward, often feel after drinking headache, inappetence, weak, feel sick, vomit, lose weight, upper right abdomen dull pain.Be alcoholic liver on inspection.This tea of back clothes after one month situation be clearly better, head is not bitterly, appetite increases, health energetically, generation such as no nausea and vomiting.
Embodiment:
1 kilogram of 2 kilograms of Folium Stevlae Rebaudianae of 3 kilograms of Herba Pelargonii Graveolentiss of 1.5 kilograms of Herba Menthaes of 6 kilograms of Flos Ginseng of 3 kilograms of Fructus Lycii of 6 kilograms of Rhizoma Alpiniae Officinarums of 3 kilograms of Fructus Jujubaes of 3 kilograms of Radix Glycyrrhizaes of 9 kilograms of Fructus Hippophaes of 4.5 kilograms of Semen Cassiaes of 3 kilograms of Folium Mori of 2 kilograms of Fructus Phyllanthis of 2 kilograms of Radix Salviae Miltiorrhizaes of 2 kilograms of Fructus Tsaokos of 3 kilograms of Caulis Bambusae In Taenia of 4 kilograms of Herb Gynostemmae Pentaphylli of 9 kilograms of Fructus Schisandrae Chinensis of 6 kilograms of Rhizoma Polygonatis of 3 kilograms of Fructus Crataegis of 3 kilograms of Pericarpium Citri Reticulataes of 6 kilograms of Flos Chrysanthemis of 6 kilograms of Fructus Mumes of 9 kilograms of Semen Hoveniae (Fructus Hoveniae)s of Radix Puerariae.
The above-mentioned raw materials medicine is chosen decontamination, oven dry, pulverizes, sieved, and the filtration paper bag of the sterilization of packing into promptly gets the teabag finished product.
Claims (7)
1. Chinese medicine preparation that relieves the effect of alcohol, protects the liver is characterized in that the content range of this medicine composition is:
Radix Puerariae 9-15 gram Semen Hoveniae (Fructus Hoveniae) 9-12 gram Fructus Mume 6-12 gram Flos Chrysanthemi 4.5-9 gram
Pericarpium Citri Reticulatae 3-9 Keshan short, bristly hair or beard 9-12 gram Rhizoma Polygonati 9-15 gram Fructus Schisandrae Chinensis 1.5-6 gram
Caulis Bambusae In Taenia 4.5-9 gram Herb Gynostemmae Pentaphylli 3-6 gram Fructus Tsaoko 3-6 gram Radix Salviae Miltiorrhizae 9-15 gram
Fructus Phyllanthi 3-9 gram Folium Mori 4.5-9 gram Semen Cassiae 9-15 gram Fructus Hippophae 3-9 gram
Radix Glycyrrhizae 3-9 gram Fructus Jujubae 6-15 gram Rhizoma Alpiniae Officinarum 3-9 gram Fructus Lycii 6-12 gram
Flos Ginseng 1.5-9 gram Herba Menthae 3-6 gram Herba Pelargonii Graveolentis 1-3 gram Folium Stevlae Rebaudianae 3-9 gram.
2. medicine according to claim 1 is characterized in that the each component percentage by weight is:
Radix Puerariae 9% Semen Hoveniae (Fructus Hoveniae) 6% Fructus Mume 6% Flos Chrysanthemi 3% Pericarpium Citri Reticulatae 3%
Fructus Crataegi 6% Rhizoma Polygonati 9% Fructus Schisandrae Chinensis 4% Herb Gynostemmae Pentaphylli 3% Caulis Bambusae In Taenia 2%
Fructus Tsaoko 2% Radix Salviae Miltiorrhizae 2% Fructus Phyllanthi 3% Folium Mori 4.5% Semen Cassiae 9%
Fructus Hippophae 3% Radix Glycyrrhizae 3% Fructus Jujubae 6% Rhizoma Alpiniae Officinarum 3% Fructus Lycii 6%
Flos Ginseng 1.5% Herba Menthae 3% Herba Pelargonii Graveolentis 2% Folium Stevlae Rebaudianae 1%.
3. medicine according to claim 1 and 2 is characterized in that it is medicinal tea, electuary, oral liquid, Tabules.
4. according to the method for preparing of the said medicinal tea of claim 3, it is characterized in that the medicine of formula ratio is chosen decontamination, oven dry, pulverize, mix and sieve, in the sterilising filtration tea bag of packing into, seal promptly and get, have on the tea bag to lead and carry short-term.
5. according to the method for preparing of the said medicament electuary of claim 3, it is characterized in that crude drug pulverizing, the decocte with water of formula ratio, the gained medicinal liquid is condensed into thick paste, add Icing Sugar, dextrin, mixing makes finished product.
6. according to the method for preparing of the said oral liquid of claim 3, it is characterized in that the Chinese herbal medicine dry product of formula ratio is ground into coarse powder, the water boil of adding crude drug weight triplication one hour goes out medicinal liquid; Add qdx water boil half an hour again, go out medicinal liquid, the secondary combining medicine, the cooling back adds 1-2 and doubly measures the ethanol mixing; Place post precipitation and get supernatant, reclaim ethanol, concentrated supernatant leaves standstill; Filter, flash to paste, add distilled water diluting, make diluent contain crude drug 20%; Add simple syrup, potassium sorbate again, through filtering, sterilization encapsulates and promptly gets the oral liquid finished product.
7. according to the method for preparing of the said tablet of claim 3, it is characterized in that Chinese medicine Fructus Mume, the Fructus Lycii decocte with water of formula ratio three times, 2 hours for the first time, second and third time each 1 hour, collecting decoction filters, and filtrating is condensed into thick paste.All the other 17 flavor Chinese medicine powders are broken into fine powder, sieve, with above-mentioned thick paste mixing, drying is ground into fine powder, with auxiliary materials and mixing, granulates, and puts 60-80 ℃ of drying.Granulate, tabletting, both.
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| CN2010102308199A CN102335379A (en) | 2010-07-20 | 2010-07-20 | Traditional Chinese preparation for relieving alcoholism and protecting livers |
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| CN102657834A (en) * | 2012-05-22 | 2012-09-12 | 湖南中医药大学 | Traditional Chinese medical composition for treatment of alcoholism and preparation process thereof |
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| CN110974888A (en) * | 2019-11-27 | 2020-04-10 | 中国科学院长春应用化学研究所 | Pharmaceutical composition with protective effect on alcoholic liver injury, preparation method and application thereof |
| CN110974888B (en) * | 2019-11-27 | 2021-11-05 | 中国科学院长春应用化学研究所 | Pharmaceutical composition with protective effect on alcoholic liver injury, preparation method and application thereof |
| CN113876890A (en) * | 2021-11-22 | 2022-01-04 | 河南医圣堂药业有限公司 | A Chinese medicinal composition for treating hepatopathy, and its preparation method |
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Address after: 100191 Beijing city Haidian District Luozhuang South Lane hongjialiyuan 2-203 Applicant after: Zhang Lizhong Address before: 100872 Beijing City, Haidian District Zhongguancun street, No. 59 people's Congress on 9-52 Applicant before: Zhang Lizhong |
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Application publication date: 20120201 |