CN101909607B - 具有尿素成分的透皮治疗系统 - Google Patents

具有尿素成分的透皮治疗系统 Download PDF

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Publication number
CN101909607B
CN101909607B CN200880124963.5A CN200880124963A CN101909607B CN 101909607 B CN101909607 B CN 101909607B CN 200880124963 A CN200880124963 A CN 200880124963A CN 101909607 B CN101909607 B CN 101909607B
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CN
China
Prior art keywords
layer
active substance
carbamide
urea
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880124963.5A
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English (en)
Chinese (zh)
Other versions
CN101909607A (zh
Inventor
M·霍斯特曼
G·霍夫曼
S·韦德斯伯格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of CN101909607A publication Critical patent/CN101909607A/zh
Application granted granted Critical
Publication of CN101909607B publication Critical patent/CN101909607B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN200880124963.5A 2008-01-30 2008-12-09 具有尿素成分的透皮治疗系统 Expired - Fee Related CN101909607B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008006791.1 2008-01-30
DE102008006791A DE102008006791B4 (de) 2008-01-30 2008-01-30 Transdermales Therapeutisches System mit Harnstoff-Komponente und Verfahren zu dessen Herstellung
PCT/EP2008/010426 WO2009095057A2 (de) 2008-01-30 2008-12-09 Transdermales therapeutisches system mit harnstoff-komponente

Publications (2)

Publication Number Publication Date
CN101909607A CN101909607A (zh) 2010-12-08
CN101909607B true CN101909607B (zh) 2014-05-14

Family

ID=40386379

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880124963.5A Expired - Fee Related CN101909607B (zh) 2008-01-30 2008-12-09 具有尿素成分的透皮治疗系统

Country Status (14)

Country Link
US (1) US9066887B2 (enExample)
EP (1) EP2234605B1 (enExample)
JP (1) JP5389824B2 (enExample)
KR (1) KR20100105866A (enExample)
CN (1) CN101909607B (enExample)
AU (1) AU2008349007B2 (enExample)
BR (1) BRPI0821975B8 (enExample)
CA (1) CA2710640C (enExample)
DE (1) DE102008006791B4 (enExample)
ES (1) ES2548295T3 (enExample)
MX (1) MX2010008334A (enExample)
PL (1) PL2234605T3 (enExample)
WO (1) WO2009095057A2 (enExample)
ZA (1) ZA201004012B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106333939A (zh) * 2016-10-09 2017-01-18 常州亚环环保科技有限公司 一种药用透皮材料的制备方法
CN109549929A (zh) * 2017-09-27 2019-04-02 天津金耀集团有限公司 一种有机固体溶液降低皮质激素药物粒径的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6280765B1 (en) * 1997-04-11 2001-08-28 L'oreal Pharmaceutical, cosmetic or dermo-pharmaceutical patch for the delivery of several active compounds of different nature

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1404583A (en) * 1971-10-08 1975-09-03 Vymatt Sa Urea compositions and methods of preparation thereof
CS164542B1 (enExample) * 1973-02-15 1975-11-07
DE2964135D1 (en) * 1978-06-16 1983-01-05 Phares Pharm Res Nv Pharmaceutical compositions containing urea
US4687481A (en) * 1984-10-01 1987-08-18 Biotek, Inc. Transdermal drug delivery system
US4699777A (en) * 1985-08-21 1987-10-13 Schering Corporation Compositions and method for enhancement of the transdermal flux of albuterol with a combination of 1-dodecyl-azacyclopheptan-2-one and urea
US5230896A (en) * 1989-10-12 1993-07-27 Warner-Lambert Company Transdermal nicotine delivery system
DE4210165A1 (de) 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
DE4310012A1 (de) * 1993-03-27 1994-09-29 Roehm Gmbh Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung
WO1997039740A1 (en) 1996-04-22 1997-10-30 Toyama Chemical Co., Ltd. Patch containing 1,2-ethanediol derivatives or salts thereof
DE19701949A1 (de) * 1997-01-13 1998-07-16 Jenapharm Gmbh Transdermales therapeutisches System
US20040018241A1 (en) * 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
GB9826656D0 (en) * 1998-12-03 1999-01-27 Novartis Ag Organic compounds
JP3962684B2 (ja) * 2000-11-06 2007-08-22 サムヤン コーポレイション 改善された水分吸収能および接着性を有する経皮投与剤
IL156353A0 (en) * 2000-12-15 2004-01-04 Schering Ag Water-free skin care formulations comprising micronized urea and method of manufacturing the same
US20050020658A1 (en) 2002-11-21 2005-01-27 Katsuyuki Inoo Selective cyclooxygenase-2 inhibitor patch
FR2867978B1 (fr) * 2004-03-29 2009-02-20 Galderma Res & Dev Patch d'amorolfine pour le traitement de l'onychomicose
DE102004028284A1 (de) * 2004-06-11 2006-01-05 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System auf Basis eines Schmelzklebstoffs zur Anwendung von Norelgestromin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6280765B1 (en) * 1997-04-11 2001-08-28 L'oreal Pharmaceutical, cosmetic or dermo-pharmaceutical patch for the delivery of several active compounds of different nature

Also Published As

Publication number Publication date
EP2234605A2 (de) 2010-10-06
BRPI0821975B8 (pt) 2023-02-07
PL2234605T3 (pl) 2016-01-29
CA2710640A1 (en) 2009-08-06
ZA201004012B (en) 2011-02-23
CN101909607A (zh) 2010-12-08
AU2008349007B2 (en) 2014-10-02
BRPI0821975B1 (pt) 2019-10-08
ES2548295T3 (es) 2015-10-15
US9066887B2 (en) 2015-06-30
WO2009095057A3 (de) 2010-03-04
AU2008349007A1 (en) 2009-08-06
DE102008006791A1 (de) 2009-08-06
HK1151716A1 (en) 2012-02-10
US20100310634A1 (en) 2010-12-09
MX2010008334A (es) 2010-08-23
JP2011510936A (ja) 2011-04-07
KR20100105866A (ko) 2010-09-30
BRPI0821975A2 (pt) 2015-06-23
EP2234605B1 (de) 2015-08-05
DE102008006791B4 (de) 2011-11-24
WO2009095057A2 (de) 2009-08-06
CA2710640C (en) 2015-12-08
JP5389824B2 (ja) 2014-01-15

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