CN101861860B - Squalene plant fungicide and uses thereof - Google Patents
Squalene plant fungicide and uses thereof Download PDFInfo
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- CN101861860B CN101861860B CN 201010212511 CN201010212511A CN101861860B CN 101861860 B CN101861860 B CN 101861860B CN 201010212511 CN201010212511 CN 201010212511 CN 201010212511 A CN201010212511 A CN 201010212511A CN 101861860 B CN101861860 B CN 101861860B
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- squalene
- fungicide
- emulsifier
- weight portion
- plant
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- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 title claims abstract description 81
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 title claims abstract description 81
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 title claims abstract description 81
- 229940031439 squalene Drugs 0.000 title claims abstract description 81
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 title claims abstract description 81
- 239000000417 fungicide Substances 0.000 title claims abstract description 29
- 230000000855 fungicidal effect Effects 0.000 title claims abstract description 26
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 19
- 239000002904 solvent Substances 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 239000003814 drug Substances 0.000 claims abstract 4
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims description 38
- 241001518731 Monilinia fructicola Species 0.000 claims description 15
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 14
- 238000002360 preparation method Methods 0.000 claims description 13
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 10
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 7
- 229920000053 polysorbate 80 Polymers 0.000 claims description 7
- 239000007921 spray Substances 0.000 claims description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 5
- -1 glycol ester Chemical class 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 4
- 239000000375 suspending agent Substances 0.000 claims description 4
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 229920000136 polysorbate Polymers 0.000 claims description 2
- 239000004094 surface-active agent Substances 0.000 claims description 2
- 241001465754 Metazoa Species 0.000 abstract description 4
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 4
- 239000000575 pesticide Substances 0.000 abstract description 4
- 241000282414 Homo sapiens Species 0.000 abstract description 2
- 230000008901 benefit Effects 0.000 abstract description 2
- 230000006378 damage Effects 0.000 abstract description 2
- 201000010099 disease Diseases 0.000 abstract description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
- 230000036541 health Effects 0.000 abstract description 2
- 230000007774 longterm Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 239000002420 orchard Substances 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 230000004071 biological effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 description 25
- 239000003921 oil Substances 0.000 description 15
- 235000019198 oils Nutrition 0.000 description 15
- 230000000843 anti-fungal effect Effects 0.000 description 11
- 229940121375 antifungal agent Drugs 0.000 description 11
- 244000144730 Amygdalus persica Species 0.000 description 8
- 235000006040 Prunus persica var persica Nutrition 0.000 description 8
- 241000233866 Fungi Species 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- 239000003905 agrochemical Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000008096 xylene Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 230000004763 spore germination Effects 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 150000001336 alkenes Chemical class 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 238000002389 environmental scanning electron microscopy Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
- 241000379194 Abies sibirica Species 0.000 description 1
- 241000195940 Bryophyta Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000195628 Chlorophyta Species 0.000 description 1
- 241000251730 Chondrichthyes Species 0.000 description 1
- 235000007926 Craterellus fallax Nutrition 0.000 description 1
- 240000007175 Datura inoxia Species 0.000 description 1
- 240000006240 Linum usitatissimum Species 0.000 description 1
- 235000004431 Linum usitatissimum Nutrition 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 244000143590 Salvia chinensis Species 0.000 description 1
- 235000007154 Salvia chinensis Nutrition 0.000 description 1
- 235000005794 Salvia japonica Nutrition 0.000 description 1
- 241000251778 Squalus acanthias Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- LWZFANDGMFTDAV-BURFUSLBSA-N [(2r)-2-[(2r,3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O LWZFANDGMFTDAV-BURFUSLBSA-N 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- 150000007854 aminals Chemical class 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 239000003026 cod liver oil Substances 0.000 description 1
- 235000012716 cod liver oil Nutrition 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 150000003421 squalenes Chemical class 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明提供了一种以角鲨烯为主要原料，再加入溶剂、增溶剂和/或乳化剂制成的杀植物真菌剂，是一种对人畜安全、环境友好型的和谐农药，对生态环境长远发展、人类的健康和病害的综合治理都具有深远的意义。本发明的角鲨烯植物杀真菌剂与传统的农药相比，具有以下的特点和优点：1、角鲨烯具有较高的生物活性；2、角鲨烯广泛存在于动植物体内，来源广泛，可以成为很好的开发资源；3、角鲨烯因其来源于自然，不易造成农药药害、毒性残留，对人畜、生态环境安全；4、容易进行人工合成且自然来源广泛，为进行工业化生产提供了便利的条件；5、结合制备型植物中其他有效杀菌成分，混配制药，能进一步增强在农田果园上的杀菌作用。The invention provides a plant fungicide made by taking squalene as the main raw material and adding solvent, solubilizer and/or emulsifier. The comprehensive management of long-term development, human health and diseases has far-reaching significance. Compared with traditional pesticides, the squalene plant fungicide of the present invention has the following characteristics and advantages: 1, squalene has higher biological activity; 2, squalene is widely present in animals and plants, and has a wide range of sources 3. Because squalene is derived from nature, it is not easy to cause pesticide damage and toxic residues, and is safe for humans, animals and the ecological environment; 4. It is easy to artificially synthesize and has a wide range of natural sources. It is suitable for industrialization The production provides convenient conditions; 5. Combined with other effective bactericidal ingredients in the prepared plants, the mixed medicine can further enhance the bactericidal effect on farmland or orchards.
Description
Technical field
The present invention relates to the new purposes of a kind of squalene plant fungicide and squalene.
Background technology
Squalene has another name called shark alkene, squalene, dog-fish oil element or cod-liver oil terpene etc., chemical formula C
30H
50, chemical name 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosa carbon six alkene.Be colourless oil liquid, have pleasant smell, oxygen uptake becomes sticky as flax oily.Relative density 0.8584, fusing point-75 ℃, the about 330 ℃/normal pressure of boiling point (decomposition), 280 ℃/2.27kPa, 285 ℃/3.3kPa, 240～242 ℃/533Pa, 110 ℃ of flash-points, index of refraction 1.4965 (20 ℃), viscosity 0.012Pa*s is dissolved in ether, benzinum, acetone and carbon tetrachloride, be slightly soluble in pure and mild glacial acetic acid, water insoluble.Squalene does not exist only in the animal body, the part such as root, leaf, skin that also is present in many plants, in Salvia japonica, tobacco leaf, Abies sibirica bark, pteridophyte, green algae and bryophyte, content is also than horn of plenty in olive oil and the palm oil.Because it has stronger activity and oxygen carrying capacity, be widely used in aspects such as healthcare products and cosmetics at present.But still there be not the application report of squalene in the preparation botanical fungicide in the existing document; Still do not have at present a kind of good with environment compatibility, to the harmonious agricultural chemicals of mammalian safe.
Summary of the invention
The object of the invention is to disclose a kind of squalene plant fungicide, and order of the present invention also is the new purposes of open squalene in the preparation plant fungicide.
The present invention seeks to be achieved through the following technical solutions:
The application of squalene in the preparation plant fungicide.
Squalene is added conventional auxiliary material, according to common process, make various forms of fungicides: missible oil, suspending agent, pulvis or spray.
Wherein, auxiliary material is solvent, can also add solubilizer and/or emulsifier.Solvent is acetone, chloroform, benzene and/or dimethylbenzene, preferred dimethylbenzene; Solubilizer, emulsifier are spans, Tweens, glycol ester class, propylene glycol ester class and/or polyethylene glycol type non-ionic surface active agent.
Wherein, the raw material of missible oil consists of in the squalene fungicide of the present invention:
Squalene 20-60 weight portion dimethylbenzene 30-70 weight portion emulsifier 5-15 weight portion.
The raw material of missible oil composition is preferably in the squalene fungicide of the present invention:
Squalene 50 weight portion dimethylbenzene 40 weight portion emulsifier 10 weight portions.
The raw material of missible oil composition is preferably in the squalene fungicide of the present invention:
Squalene 30 weight portion dimethylbenzene 60 weight portion emulsifier 10 weight portions.
The raw material of missible oil composition is preferably in the squalene fungicide of the present invention:
Squalene 40 weight portion dimethylbenzene 50 weight portion emulsifier 10 weight portions.
Wherein, emulsifier is that the HLB value is 15 Tween-80.
The preparation method of missible oil is in the squalene fungicide of the present invention: with the squalene xylene soluble, add emulsifier therein again, dissolving namely can be used for sterilization.
Wherein, described fungi can be Monilinia fructicola.
The invention provides a kind ofly to person poultry safety, environmentally friendly harmonious agricultural chemicals, the comprehensive regulation of ecotope long term growth, human beings'health and disease is all had profound significance.Squalene plant fungicide of the present invention is compared with traditional agricultural chemicals, have following characteristics and advantage: 1, squalene has higher biologically active, through the spore germination determination experiment, can be when concentration be 2000 μ g/ml, the spore of the brown germ of peach is suppressed by squalene fully.Squalene with acetone diluted after, through suppressing the mycelial growth test, can be when concentration be 2000g/ml, squalene can reach 92.64% to the bacteriostasis rate of the brown germ of peach, visible squalene has stronger pesticide developing and is worth.2, squalene extensively is formed in the bodies of aminal and plant, and wide material sources can become well and exploit natural resources; 3, squalene derives from nature because of it, is difficult for causing pesticide injury, toxic residue, to people and animals, ecological environment security; 4, manually synthesize easily and natural source extensive, for carrying out the condition that suitability for industrialized production is provided convenience; 5, in conjunction with other effective sterilization components in the preparation type plant, pharmaceutical mixture can further strengthen the bactericidal action on the orchard, farmland; 6, missible oil is solvent with dimethylbenzene in the squalene plant fungicide of the present invention, can increase the solvability of squalene in water, and has the effect that promotes agricultural chemicals infiltration plant epidermis concurrently.
Description of drawings
Fig. 1: squalene is to the influence of peach brown rot fungus spore germination;
Fig. 2: the Monilinia fructicola that squalene is handled under the ESEM and spore and the mycelia form of contrast;
Fig. 3: squalene is handled spore structure and the contrast of Monilinia fructicola under the transmission electron microscope.
Following experimental example and embodiment are used for further specifying but are not limited to the present invention.
The screening experiment of experimental example 1 solvent of the present invention.
This experiment is screened the solvent of squalene, adopt acetone, chloroform, benzene, dimethylbenzene as the solvent of squalene respectively, adopt growth rate method, Monilinia fructicola is carried out bactericidal assay, concentration is made as 1500 μ g/ml, add a Tween-80 and make emulsifier, the results are shown in Table 1, optimize and select dimethylbenzene as optimum solvent.
Squalene is to the inhibitory action of Monilinia fructicola in table 1 different solvents
Experimental example 2 squalene plant fungicides of the present invention are to the inhibition experiment of Monilinia fructicola.
Prepare squalene plant antifungal missible oil of the present invention according to the embodiment of the invention 1 described raw material and method, this missible oil suppresses experiment through water dilution (extension rate sees Table 2) to Monilinia fructicola.Experimental result sees Table 3:
The table 2 concentration dilution multiple table of comparisons
Table 3 squalene plant antifungal of the present invention missible oil suppresses the result to the biologically active of Monilinia fructicola
Annotate: lowercase alphabet shows that the F value less than 0.05, has significant difference among the figure.
Experimental example 3 squalenes are to the fungus spore germination determination experiment
With acetone squalene is diluted to variable concentrations, measures it to the sprouting situation of peach brown rot fungus spore, result of the test is seen Fig. 1, and when concentration was 2000 μ g/ml, the spore of the brown germ of peach was suppressed by squalene fully.
Continuation has been carried out further research to the antifungal mechanism of squalene, handling the peach brown rot fungus with squalene is processed group, handling the peach brown rot fungus with the end through squalene is control group, and ESEM is also observed, and it is coarse and uneven to found that the Monilinia fructicola spore surface becomes; Mycelium also be distorted, rupture (as accompanying drawing 2).Transmission electron microscope observing finds that cavity appears in the organelle degraded of peach brown rot bacterial cell, and kytoplasm aggegation, appearance are run off, and cell structure is destroyed, and causes cell death (as accompanying drawing 3).Electron microscopic observation result further checking squalene of the present invention has significant inhibitory effect to Monilinia fructicola.
Following embodiment all can realize the described effect of above-mentioned experimental example.
Embodiment
Embodiment 1: squalene plant antifungal missible oil of the present invention
Squalene 50kg dimethylbenzene 40kg HLB value is 15 Tween-80 10kg.
With the squalene xylene soluble, add the HLB value therein again and be 15 Tween-80, dissolving can be adopted spray pattern control Monilinia fructicola.
Embodiment 2: squalene plant antifungal missible oil of the present invention
Squalene 30kg dimethylbenzene 60kg HLB value is 15 Tween-80 10kg.
With the squalene xylene soluble, add emulsifier therein again, dissolving can be adopted spray pattern control Monilinia fructicola.
Embodiment 3: squalene plant antifungal missible oil of the present invention
Squalene 40kg dimethylbenzene 50kg HLB value is 15 Tween-80 10kg.
With the squalene xylene soluble, add emulsifier therein again, dissolving can be adopted spray pattern control Monilinia fructicola.
Embodiment 4: squalene plant antifungal suspending agent of the present invention
Squalene added in the solvent acetone dissolve, add Arlacel-20 again, make squalene plant antifungal suspending agent according to common process, adopt the spraying mode to prevent and treat plant epiphyte.
Embodiment 5: squalene plant antifungal pulvis of the present invention
According to common process, add conventional auxiliary material, squalene is made pulvis, adopt the spraying mode to prevent and treat plant epiphyte.
Embodiment 6: squalene plant antifungal spray of the present invention
Squalene added in the solvent chloroform dissolve, add ethylene glycol again, make squalene plant antifungal spray according to common process, adopt the spraying mode to prevent and treat plant epiphyte.
Claims (7)
1. the application of squalene fungicide in preparation control plant epiphyte medicine, the raw material of this fungicide consists of: squalene 20-60 weight portion, dimethylbenzene 30-70 weight portion, emulsifier 5-15 weight portion; It is characterized in that wherein said plant epiphyte is Monilinia fructicola.
2. the application of a kind of squalene fungicide as claimed in claim 1 in preparation control plant epiphyte medicine is characterized in that the raw material of this fungicide consists of:
Squalene 50 weight portion dimethylbenzene 40 weight portion emulsifier 10 weight portions;
Or
Squalene 30 weight portion dimethylbenzene 60 weight portion emulsifier 10 weight portions;
Or
Squalene 40 weight portion dimethylbenzene 50 weight portion emulsifier 10 weight portions.
3. the application of a kind of squalene fungicide as claimed in claim 1 or 2 in preparation control plant epiphyte medicine is characterized in that wherein said emulsifier is that the HLB value is 15 Tween-80.
4. the application of squalene in the preparation plant fungicide is characterized in that wherein said plant epiphyte is Monilinia fructicola.
5. the application of squalene as claimed in claim 4 in the preparation plant fungicide, it is characterized in that when the preparation plant fungicide, squalene is added conventional auxiliary material, according to common process, make various forms of fungicides: missible oil, suspending agent, pulvis or spray.
6. the application of squalene as claimed in claim 5 in the preparation plant fungicide is characterized in that wherein said auxiliary material is solvent: acetone, chloroform, benzene and/or dimethylbenzene.
7. the application of squalene as claimed in claim 6 in the preparation plant fungicide is characterized in that wherein said auxiliary material also adds solubilizer and/or emulsifier; Described solubilizer, emulsifier are spans, Tweens, glycol ester class, propylene glycol ester class and/or polyethylene glycol type non-ionic surface active agent.
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| CN 201010212511 CN101861860B (en) | 2010-06-22 | 2010-06-22 | Squalene plant fungicide and uses thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201010212511 CN101861860B (en) | 2010-06-22 | 2010-06-22 | Squalene plant fungicide and uses thereof |
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| CN101861860A CN101861860A (en) | 2010-10-20 |
| CN101861860B true CN101861860B (en) | 2013-07-10 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101869103B (en) * | 2010-06-22 | 2013-07-10 | 北京农学院 | Plant miticide of squalene and applications thereof |
| CN103798362B (en) * | 2014-03-11 | 2015-09-02 | 华中农业大学 | The application of terbinafine HCl after oranges and tangerines are adopted in anti-corrosive fresh-keeping |
| CN114395401B (en) * | 2021-12-24 | 2023-11-24 | 神究富硒农业发展(山东)有限公司 | Cell repair liquid, preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484599A (en) * | 1993-11-30 | 1996-01-16 | The President And Fellows Of Harvard College | Control of insect pests |
| CN101869103A (en) * | 2010-06-22 | 2010-10-27 | 北京农学院 | A kind of squalene plant acaricide and its application |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006008573A (en) * | 2004-06-25 | 2006-01-12 | Katayama Chem Works Co Ltd | Wood preservative and wood processing method using the same |
| US20080146444A1 (en) * | 2006-12-19 | 2008-06-19 | Polymer Ventures, Inc. | Method and compositions for improving plant growth |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5484599A (en) * | 1993-11-30 | 1996-01-16 | The President And Fellows Of Harvard College | Control of insect pests |
| CN101869103A (en) * | 2010-06-22 | 2010-10-27 | 北京农学院 | A kind of squalene plant acaricide and its application |
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| CN101861860A (en) | 2010-10-20 |
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