CN101856401A - Externally-applied Chinese medical composition for treating insomnia - Google Patents
Externally-applied Chinese medical composition for treating insomnia Download PDFInfo
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- CN101856401A CN101856401A CN201010205073A CN201010205073A CN101856401A CN 101856401 A CN101856401 A CN 101856401A CN 201010205073 A CN201010205073 A CN 201010205073A CN 201010205073 A CN201010205073 A CN 201010205073A CN 101856401 A CN101856401 A CN 101856401A
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Abstract
The invention provides an externally-applied Chinese medical composition for treating insomnia. According to a formula, the Chinese medical composition comprises the components of tuber fleeceflower stem, flower of silktree albizzia, thinleaf milkwort root-bark, nacre mother of pearl, fructus ligustri lucidi and Coptis chinensis in a mass ratio of 6:6:6:5:5:2. The formula of the Chinese medical composition is reasonable. Based on the acupoint therapy of traditional Chinese medicament and the percutaneous absorption theory of modern pharmacy, the externally-applied Chinese medical composition is ground into powder and added with yellow rice or millet wine to form paste to be applied at Sanyinjiao, Yongquan, Zhaohai and Neiguan points on two sides of a human body. The externally-applied Chinese medical composition has the advantages of convenient medicament administration method, long-lasting medicament effect and few adverse reactions. In the invention, the Chinese medicament is applied at the points, the action of the Chinese medicament is transmitted by meridians and collaterals to regulate Qi and blood and cross Yin and Yang by 'conducting Yang from Yin and conducting Yin from Yang', and thus, the disease can be cured. The effective rate of the externally-applied Chinese medical composition is 72.1 percent and the cure and marked improvement rate of the externally-applied Chinese medical composition is 17.6 percent, so the externally-applied Chinese medical composition is an effective medicament for treating insomnia.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to the external medicine composition of Cure for insomnia.
Background technology
Insomnia claims DIMS (DIMS) again, is often referred to the patient does not satisfy and influence the social function on daytime to the length of one's sleep or quality a kind of subjective experience.The common cause that causes insomnia has: psychological factor: various contradictions in life, the work and the anxiety, depression, anxiety, excitement, the indignation that are caused of difficulty or ponder over too much etc.; Physiologic factor: psychentonia, hunger, fatigue, sexual excitation and some diseases, along with the rising at age, sleeper effect also can change; Medicine factor: drink, drug dependence, drug dependence and withdrawal symptom etc.; Bad environment and custom: bad environment or bad habit all can influence sleep for most people.
Classify by the course of disease: NIH (NIH 1983) is divided into insomnia: the transience insomnia continues a few days usually; Of short duration insomnia continues 1-3 week; Long-term insomnia: continue more than 3 weeks.According to the characteristics of insomnia, insomnia can be divided into three kinds again: 1. initial insomnia, be meant difficulty falling asleep, and arrive after midnight and can fall asleep.2. discontinuity insomnia sleeping rather is not meant, wakes up with a start easily, and nightmare is often arranged.3. terminal point insomnia is meant and falls asleep not difficultly that but the persistent period is not long, can not fall asleep after awake after midnight again.Classify by the order of severity: slight, accidental, little to the quality of life influence; Moderate takes place every night, moderate influence quality of life, accompanies certain symptom (irritability, anxiety, tired etc.); Severe takes place every night, has a strong impact on quality of life, and clinical symptoms is had outstanding performance.Chinese medicine is called " being insomnia ", " insomnia ", " must not crouch ", " unable to close the eyes ".This disease and conscience spleen kidney are in close relations, because of the source of blood, give birth to by essence of water and grainization, on give in the heart, then gains in depth of comprehension are supported; Be hidden in liver, then the liver body is soft; Have under one's command in spleen, then biochemistry does not stop; Adjusting degree of having is changed and is smart, is built in kidney, holds on the kidney essense in the heart, meets at kidney under the motive, keep in the cloudy essence, Wei Yang protect in outside, negative and positive are coordinated, then the mind peacefulness.The traditional Chinese medical science of tracing it to its cause is thought insomnia because visceral dysfunction, and negative and positive of qi and blood is become estranged, YANG failing to enter YIN, YIN failing to keep YANG well, mental derangement, and cause uneasy sleeping at night, even disease such as lie awake all night.
The method of Cure for insomnia is varied at present, and the method for the most frequently used Cure for insomnia remains Drug therapy.Western medicine somnifacient commonly used and tranquilizer though can produce instant curative effect, are taken medicine for a long time, and patient increases the toleration of medicine, and produce the dependency to medicine, and it easily produces the toxic and side effects of medicine for a long time.(Diao Yuanming; Chen Qun; The road is gorgeous.The tenth collection of thesis 2009:200-204 of scientific seminar of Diagnostics of Chinese Medicine branch of China Association of Traditional Chinese Medicine)
Summary of the invention
In order to enrich the Chinese medicine medicine of Cure for insomnia.The invention provides a kind of external medicine composition of Cure for insomnia.Described external medicine composition is selected acupoint application of Chinese herb for use, by the meridians conduction, and QI and blood regulating, " guiding QI in YIN meridian to expel the pathogen in YANG meridian, guiding QI in YANG meridians to expel the pathogen in YIN meridian " intersects negative and positive, thereby reaches the purpose of cure diseases.
The composition of the prescription of the external medicine composition of Cure for insomnia provided by the invention and quality proportioning are as follows: the mass ratio of Caulis Polygoni Multiflori, Flos Albiziae, Radix Polygalae, Concha Margaritifera, Fructus Ligustri Lucidi and Rhizoma Coptidis is 6: 6: 6: 5: 5: 2.
Its sweet in the mouth of Caulis Polygoni Multiflori has the effect " book on Chinese herbal medicine justice " of tranquilizing by nourishing the heart to say that it " controls to pacify less night and sleep "; Its extract of modern pharmacological research hands over rattan glycoside, Caulis Polygoni Multiflori anthraquinone and three kinds of compositions of Caulis Polygoni Multiflori flavone that the effect of improving animal sleep is all arranged.Flos Albiziae, sweet in the mouth is flat, and the Chang Yu resolving depression of calming the nerves is used for restlessness of asrhenia type and insomnia more, and depression is not joyous, diseases such as forgetful dreaminess, Shennong's Herbal is said: " Herba Albiziae master the five internal organs, and will make us happy carefree "; Modern pharmacological research shows, the Flos Albiziae delaying sanility, improve memory, strengthen sleep, the Flos Albiziae decoct, can obviously reduce spontaneous activity and the passive activity of mice, the central inhibitory action of obviously collaborative barbiturate prolongs pentobarbital sodium, sodium phenobarbital induced mice anesthesia duration.The Concha Margaritifera sweet in the mouth is flat, suppressing the hyperactive liver and subsiding YANG, and tranquilizing mind curing mainly the palpitation with fear insomnia, and irritability, " Chinese medicine voluminous dictionary " are pointed out " this thing (Concha Margaritifera) is double goes into the heart, liver two warps, with Concha Haliotidis but go into the Liver Channel person is different, so relate to the mind patient, must this ".Radix Polygalae, bitter in the mouth, the property suffering, temperature, GUIXIN, kidney, lung meridian, the Fructus Alpiniae Oxyphyllae of calming the nerves, gas and mind tranquilizing and the heart calming happily, can lead to kidney qi again and strong will is not forgotten, be restoring normal coordination between the heart and kidney, stable mind, the good merchantable brand of the strong knowledge of Fructus Alpiniae Oxyphyllae is used for the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, " book on Chinese herbal medicine is just " speech: " Radix Polygalae, the wholwe-hearted kidney of merit, so but the relieving palpitation spasmolytic; the peace that exorcises evil spirits dream ... " modern pharmacological research shows, active component 3,4 in the Radix Polygalae, 5-trimethoxy cinnamic acid (TMCA) all has synergism to barbiturate, polygalic acid has dopamine and varies receptor antagonist character external, can be used as tranquilizer and uses.Fructus Ligustri Lucidi sweet in the mouth, hardship, cool in nature, take a tonic or nourishing food to build up one's health Liver and kidney, be the product of clear benefit, the essentials of Matea Medica speech: " its liver and kidney tonifying, settling five organs ... " Rhizoma Coptidis bitter in the mouth, it is indispensable to control all diseases of heart-fire, is used for hyperactivity of heart-fire, dysphoria and insomnia, " property of medicine is separated " speech: " Rhizoma Coptidis, bitter in the mouth, cold in nature; nontoxic, go into heart channel ", " book on Chinese herbal medicine is newly organized " speech: Rhizoma Coptidis, go into the heart and collaterals of the uterus, pathogenic fire purging also can be gone into liver, ask to join one the medicine of tying-in greatly, all can go into it, and it is outstanding also full-time to go into the heart.
We are with Caulis Polygoni Multiflori, and Flos Albiziae is a monarch drug, reuse Caulis Polygoni Multiflori in the side and nourish heart to calm the nerves, and the Flos Albiziae resolving depression is to calm the nerves, and the two Chang Xiangxu is a usefulness, gets the effect of calming the nerves; With the Concha Margaritifera is ministerial drug, strengthens the effect that monarch drug is calmed the nerves, and is the ministerial drug restoring normal coordination between the heart and kidney with the Radix Polygalae, and heart-fire and kidney water were both helped, and negative and positive intersect, and the ministerial drug Fructus Ligustri Lucidi is the product of tonifying liver kidney yin, to change promoting generation of vital essence and blood, the mind must be supported, and keeping a sound mind helps cloudy to hold back sun; Rhizoma Coptidis is an adjuvant drug, and heat extraction is with consolidating YIN, in eliminating heart-fire, make to draw blood and must support, and coordination between the heart and kidney, water-ascending and fire-descending, normal and the Caulis Polygoni Multiflori treatment disarmony between the heart and kidney that matches is had a sleepless night.
As extra conductant ingredient, say " all wine alcohol is different, and only rice wine is gone into medicinal " (rice wine is yellow wine) with yellow wine on the Compendium of Material Medica, yellow wine has Tong Qumai, thick the intestines and stomach, profit skin, wet dissipation gas, support temper, hold up liver, remove therapeutical effect such as the wind therapeutic method to keep the adverse QI flowing downwards.Yellow wine can help improve blood circulation simultaneously, enhances metabolism.
Using traditional traditional Chinese medical science acupoint therapy and modern pharmacy Transdermal absorption theory, adopt Chinese medicine composition acupoint application treatment Cure for insomnia, is characteristic of the present invention.
Modern study shows, constantly stimulate human acupoint, can make the various teleneurons of place, acupuncture point skin enter active state, constantly promote nerve, body fluid regulating action and the immunologic function of human body, improve the functional activity of each internal organs organ, thereby reach the purpose of treatment disease.We select acupoint application of Chinese herb for use, by the meridians conduction, and QI and blood regulating, " guiding QI in YIN meridian to expel the pathogen in YANG meridian, guiding QI in YANG meridians to expel the pathogen in YIN meridian " intersects negative and positive, thereby reaches the purpose of cure diseases.
Sp 6 is Three Yin Channels of Foot (spleen meridian, kidney meridian, a liver channel of foot-Jueyin) confluent acupoint, adopts nearly portion to select the principle in cave, better brings into play the dual function of medicine and meridional point.Interior closing is the luo-connecting point of pericardium meridian, be one of the eight confluent acupoints connecting the eight extra channels, lead to that Zhaohai also is a eight confluent acupoints connecting the eight extra channels again in Yin Link Channel, Yin Link Vessel, logical yinqiao channel, choose two caves, nourishing YIN is to make sun, YIN and YANG balancing, insomnia spontaneous recovery, close simultaneously and join SANYINJIAO acupoint, also can orderly and clearly feelings will to calm the nerves, Zhaohai cooperates the insomnia that can treat hyperactivity of fire caused by deficiency of YIN with SANYINJIAO acupoint.Spring belongs to kidney meridian, says in the Huangdi's Internal Classics: " kidney is for spring, and the spring person foot heart also." " supernatant Lingbao City rule of treatment " speech: " its gas reaches the heart, and its former going up is led to the Sublingual, and name is said spring ", so with this cave restoring normal coordination between the heart and kidney.
The using method of the external medicine composition of Cure for insomnia provided by the invention is as follows: the external medicine composition of Cure for insomnia is ground into powder, add yellow wine and mix well into pasty state, evenly be coated in the medically acceptable strile gauze dressing, preceding sp 6, spring, Zhaohai, the Neiguan acupoint that spread on the human body bilateral in 30 minutes of sleeping every night kept somewhere and taken off after 8-10 hour.Each concrete consumption is as described in the embodiment 1.14 days is a course of treatment.
Taboo: this Chinese medicine composition skin allergy person is forbidden.
Criterion of therapeutical effect and therapeutic outcome criterion of therapeutical effect: unify Sleep efficiency value formula: sleep rate=(actual time for falling asleep/go to bed) to total time * 100% of getting up with reference to international standard.Wherein actual time for falling asleep persistent period in the index that is equivalent to have a sleepless night.
Recovery from illness: transference cure, sleep rate reach more than 75% (to be withdrawn under the condition of sleeping pill).
Produce effects: remission, sleep rate reach more than 65% (withdraws under the condition of sleeping pill).
Effectively: doing well,improving, sleep rate reach more than 55% (to be withdrawn under the condition of sleeping pill or dose minimizing 3/4) substantially.
Invalid: symptom such as preceding, the sleep rate is below 40%.Keep by sleeping pill.
Treatment case and therapeutic effect statistics:
According to mentioned above principle, use Drug therapy insomniac's 96 examples of the present invention, wherein, male 37 examples, women 59 examples; 20～62 years old age, average 38.6 years old; The course of disease 5 days～2.1 years, average 7.2 months.Accidental 41 examples; Moderate 32 examples; Severe 23 examples.
96 routine clinical cases, one the course of treatment administration time be 14 days.
Recovery from illness and obvious effective rate 17.6%, 2 examples of fully recovering, produce effects 15 examples; Totally 17 people, male 6 examples, women 11 examples; 20～42 years old age, average 25.2 years old; The course of disease 5 days～8 months, average 1.1 months.Slight 9 examples; Moderate 8 examples.
Effective percentage is 72.1%; Totally 69 people, male 25 examples, women 44 examples; 22～62 years old age, average 31.8 years old; The course of disease 5 days～2.1 years, average 3.1 months.Slight 31 examples; Moderate 24 examples; Severe 14 examples.
Invalid is 10.3%; Totally 10 people, male 6 examples, women 4 examples; 24～60 years old age, average 41.6 years old; The course of disease 1 month～2 years, average 1.2 years.Slight 1 example; Severe 9 examples.
Beneficial effect: the external medicine composition of Cure for insomnia provided by the invention, Caulis Polygoni Multiflori, Flos Albiziae, Radix Polygalae, Concha Margaritifera, Fructus Ligustri Lucidi, the Chinese medicine composition that Rhizoma Coptidis is formed sticks in human body bilateral sp 6, spring, Zhaohai, Neiguan acupoint.This Chinese medicine composition reasonable recipe, full side plays restoring normal coordination between the heart and kidney altogether, regulation between water and fire, negative and positive intersect, the merit of the peaceful will of calming the nerves.Modern study shows, constantly stimulate human acupoint, can make the various teleneurons of place, acupuncture point skin enter active state, constantly promote nerve, body fluid regulating action and the immunologic function of human body, improve the functional activity of each internal organs organ, thereby reach the purpose of treatment disease.Select acupoint application of Chinese herb for use, by the meridians conduction, QI and blood regulating, " guiding QI in YIN meridian to expel the pathogen in YANG meridian, guiding QI in YANG meridians to expel the pathogen in YIN meridian " intersects negative and positive, thereby reaches the purpose of cure diseases.The Chinese medicine application therapy is easy, quick, safe and reliable, have no side effect, and the diagnosis and treatment expense is cheap, is applicable to that different medical unit introduces, promotes, and can be accepted by vast insomniac.Its effective percentage is 72.1%, and recovery from illness and obvious effective rate 17.6% are a kind of active drugs that is used for the treatment of insomnia.
The specific embodiment
Embodiment 1
The external medicine composition of Cure for insomnia.Its prescription is as follows: Chinese medicine Caulis Polygoni Multiflori 6g, Flos Albiziae 6g, Radix Polygalae 6g, Concha Margaritifera 5g, Fructus Ligustri Lucidi 5g and Rhizoma Coptidis 2g.
The using method of this Chinese medicine composition is as follows: the external medicine composition of Cure for insomnia is ground into powder, add yellow wine and mix well into pasty state, evenly be coated in the big medically acceptable strile gauze dressing such as 8 grades, sleep every night on 8 acupuncture points of preceding sp 6, spring, Zhaohai and the Neiguan acupoint that spread on the human body bilateral in 30 minutes respectively, keep somewhere and take off after 8-10 hour.14 days is a course of treatment.
Taboo: this Chinese medicine composition skin allergy person is forbidden.
Claims (2)
1. the external medicine composition of Cure for insomnia is characterized in that, the composition and the mass ratio of its prescription are as follows: the mass ratio of Caulis Polygoni Multiflori, Flos Albiziae, Radix Polygalae, Concha Margaritifera, Fructus Ligustri Lucidi and Rhizoma Coptidis is 6: 6: 6: 5: 5: 2.
2. the external medicine composition of Cure for insomnia as claimed in claim 1 is characterized in that, its prescription is as follows: Chinese medicine Caulis Polygoni Multiflori 6g, Flos Albiziae 6g, Radix Polygalae 6g, Concha Margaritifera 5g, Fructus Ligustri Lucidi 5g and Rhizoma Coptidis 2g.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800463A (en) * | 2014-02-18 | 2014-05-21 | 河南中医学院 | Traditional Chinese medicine granules for treating insomnia |
| CN119732996A (en) * | 2024-12-27 | 2025-04-01 | 广东工业大学 | A Chinese medicine sleep-aiding soluble microneedle patch and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1973889A (en) * | 2006-11-07 | 2007-06-06 | 任广来 | Insomnia treating Chinese medicine |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1973889A (en) * | 2006-11-07 | 2007-06-06 | 任广来 | Insomnia treating Chinese medicine |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800463A (en) * | 2014-02-18 | 2014-05-21 | 河南中医学院 | Traditional Chinese medicine granules for treating insomnia |
| CN119732996A (en) * | 2024-12-27 | 2025-04-01 | 广东工业大学 | A Chinese medicine sleep-aiding soluble microneedle patch and preparation method thereof |
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| CN101856401B (en) | 2011-09-21 |
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