CN104547131A - Traditional Chinese medicine composition for treating prosopospasm - Google Patents
Traditional Chinese medicine composition for treating prosopospasm Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating prosopospasm, which is prepared from the following active ingredients: a spina date seed, ganoderma lucidum, valerian, schisandra chinensis, radix paeoniae alba, mulberries, flos rosae rugosae, tribulus terrestris, horsetail, magnetite, chrysophoron and liquorice. The traditional Chinese medicine composition for treating the prosopospasm finds a new path to treat the prosopospasm from an emotional theory, has a stable curative effect and few adverse effects, is convenient and safe to use and is a special medicine for treating the prosopospasm. Water decoction of the traditional Chinese medicine composition for treating the prosopospasm is used for treating 30 patients; after treatment for 4-6 weeks, a treatment group has a total effective rate of 90.00%, and a control group has a total effective rate of 80.00%; a difference in the total effective rates between the two groups has statistical significance (P less than 0.05); six cases in the control group have adverse effects; the treatment group has no adverse effect; and a difference in adverse effect incidence between the two groups has statistical significance (P less than 0.05).
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly one treats facial spasm Chinese medicine composition.
Background technology
Facial spasm is muscle rigidity within the scope of a kind of Silent Neuritis, intermittence, the domination of not autonomous, irregular ipsilateral neural institute or grand mal, morbidity mostly is orbicularis oculi intermittence in early days and twitches, after diffuse to other muscle of a side surface part gradually, patient is uncontrollable, fall asleep after stop.Clinical many with symptoms such as dizzy, tinnitus, feeling of fullness in the head are uncomfortable, irritated, symptom is that Progressive symmetric erythrokeratodermia increases the weight of, often because of psychentonia, excited and tired and bring out or aggravate.Primary disease is more common in women, and touching refractory, easily recurs, and has a strong impact on patient work and quality of life.Western medical treatment comprises operation, nerve block, radio frequency, Drug therapy etc., because of itself or have certain risk or side effect many, or relapse rate is high, and patient not easily accepts.Chinese traditional treatment mainly adopts acupuncture and moxibustion treatment, even if drug application therapy, concrete grammar or folk prescription are added and subtracted or treatment by typing, its curative effect how, depends on the height of doctor's professional skill to a great extent, and repeatedly go to a doctor, bring inconvenience to patient, and cause the significant wastage of social resources.Therefore, the treatment facial spasm special-purpose medicaments that development stable curative effect, untoward reaction are few, easy to use, safe is needed badly.
Summary of the invention
The object of the invention is to overcome above-mentioned deficiency existing in prior art, provide one to treat facial spasm Chinese medicine composition.
In order to realize foregoing invention object, the invention provides following technical scheme:
One treats facial spasm Chinese medicine composition, the medicament be made up of the crude drug of following mass ratio: Semen Ziziphi Spinosae 12 ~ 18 parts, Ganoderma 2 ~ 4 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Schisandrae Chinensis 4 ~ 8 parts, the Radix Paeoniae Alba 25 ~ 35 parts, 8 ~ 12 parts, Fructus Mori, Flos Rosae Rugosae 4 ~ 8 parts, Fructus Tribuli 6 ~ 10 parts, Herba Equiseti Hiemalis 6 ~ 10 parts, Magnetitum 15 ~ 25 parts, succinum 1 ~ 3 part, 4 ~ 6 parts, Radix Glycyrrhizae.
Herbal pharmacology effect of the present invention is as follows:
Semen Ziziphi Spinosae: sweet, sour, flat, GUIXIN, liver, gallbladder meridian.Nourish heart the liver benefiting, calms the nerves, arresting sweating.Semen Ziziphi Spinosae has calmness, hypnosis and antiarrhythmic effect, and can work in coordination with the central inhibitory action of barbiturate; There are convulsion, analgesia, body-temp. reducing, hypotensive effect; Semen Ziziphi Spinosae also has blood fat reducing, anti-hypoxia, antitumor, anticoagulant, strengthens immunologic function and the effect of excited uterus.
Ganoderma: sweet, flat, GUIXIN, lung, liver, kidney channel.Invigorating QI and tranquilization, relieving cough and asthma.Ganoderma has immunomodulating, blood sugar lowering, blood fat reducing, antioxidation, defying age and antitumor action; Can purify the blood, liver function protecting; There are calmness, convulsion, heart tonifying, arrhythmia, blood pressure lowering, antitussive and antiasthmatic effect.In addition, Ganoderma also has anticoagulation, anticoagulant and anti-allergic effects.
Rhizoma et radix valerianae: pungent, sweet, warm, GUIXIN, Liver Channel.Calm the nerves and regulate the flow of vital energy, promoting blood circulation and stopping pain.Rhizoma et radix valerianae has tranquilizing effect, and energy is dilating coronary blood vessel obviously, improves myocardial ischemia, reduces myocardial oxygen consumption, arrhythmia.
Fructus Schisandrae Chinensis: sour, sweet, warm, returns lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Fructus Schisandrae Chinensis all has excitation to nervous system maincenter at different levels, all has impact to corticocerebral excitement and process of inhibition, makes it to tend to balance; There is excitation to respiratory system, have antitussive and phlegm-dispelling functions; Can reduce blood pressure, function of gallbladder promoting, reduction serum transaminase, have protective effect to hepatocyte; Energy enhancing body is to the defence capability of nonspecific stimulation.
The Radix Paeoniae Alba: bitter, acid, to be slightly cold, returns liver, spleen channel.Nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG.The Radix Paeoniae Alba has immunity moderation, antiinflammatory, protects the liver, spasmolytic, analgesia, calmness, anti-frightened, antipyretic, antioxidation, resisting fatigue and the effect of phytoestrogen sample.
Fructus Mori: sweet, sour, cold, returns liver, kidney channel.Nourishing YIN and supplementing blood, promotes the production of body fluid and moisturizes.Fructus Mori has moderate to promote LT effect; Can promote that T cell is ripe, thus old and feeble T cell function is restored; Facilitation is had to young mouse humoral immune function; Facilitation is had to the growth of grain system CFU-GM; It reduces erythrocyte membrane NA
+-K
+the activity of-ATP enzyme may be one of action principle of its YIN nourishing; It prevents the leukopenic effect of caused by cyclophosphamide.
Flos Rosae Rugosae: sweet, micro-hardship, temperature, returns liver, spleen channel.Dispersing the stagnated live-QI to relieve the stagnation of QI, promoting blood circulation and stopping pain.Flos Rosae Rugosae has the effect of promotion bile secretion, has certain protective effect to experimental animal models myocardial ischemia.
Fructus Tribuli: pungent, bitter, tepor, slightly poisonous, returns Liver Channel.Suppressing the hyperactive liver is soothing the liver, dispelling pathogenic wind for improving eyesight.Fructus Tribuli has blood pressure lowering, diuresis, heart tonifying, raising body's immunity, strong, defying age, reduction blood glucose, anti-allergic effects.
Herba Equiseti Hiemalis: sweet, bitter, flat, returns lung, Liver Channel.Dispelling wind and heat pathogens, improving acuity of vision and removing nebula.Herba Equiseti Hiemalis has obvious blood vessel dilating, hypotensive effect, and can increase coronary artery blood flow, makes decreased heart rate; Suppress the effects such as nervus centralis, antiinflammatory, convergence and diuresis in addition.
Magnetitum: salty, cold, GUIXIN, liver, kidney channel.Tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, helping inspiration to relieve asthma.Magnetitum has relieving convulsion, anticonvulsant action, has synergism with amobarbital sodium, can extend its length of one's sleep to mice, have antagonism, the incubation period of convulsions is obviously extended to the mice convulsion that strychnine causes.
Succinum: sweet, flat, GUIXIN, liver, urinary bladder channel.Tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis, inducing diuresis for treating stranguria syndrome.Succinum has central inhibitory action; can obviously reduce mice autonomic activities; extend length of one's sleep of pentobarbital sodium, and rat audiogenic convulsion and white mice galvanic shock are reacted have protective effect, its time of occurrence can be extended to the convulsions that picrotoxin, strychnine, semicarbazides cause.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.Radix Glycyrrhizae has antiinflammatory, antiallergic, diuresis, blood fat reducing, hepatoprotective effect and estrogenic activity.
Chinese medicine is thought, facial spasm belongs to categories such as " wind card " " spasm syndrome " " muscle is cautious " " eyelid twitch " " muscular contractures ", and pathologic basis is void, wind, expectorant, the stasis of blood, for pathogenesis determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs numerous and complicated, is difficult to research and develop special-purpose medicaments.Primary disease is many to be brought out by Nervous and Mental Factors etc., therefore can simplify literary writing by leaving out superfluous words, and controls from emotional disorder opinion.Chinese medicine is thought, The heart controls mental activities, liver controlling conveyance and dispersion, and " all wind trembling and dizziness all belong to liver ", conscience two is dirty the closest with facial spasm onset relation, therefore, controls and should reinforcing the heart nourish blood, easing the affected liver dispelling wind, tranquillizing and allaying excitement.The present invention adopts Semen Ziziphi Spinosae, Ganoderma, Rhizoma et radix valerianae reinforcing the heart gas, and nourish heart blood; Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Fructus Mori nourish blood yin fluid astringing; Flos Rosae Rugosae, Fructus Tribuli, Herba Equiseti Hiemalis's dispelling wind resolving depression; Magnetitum, succinum tranquillizing the mind by relieving convulsion; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, and close Radix Paeoniae Alba sour and sweet drugs can transforme into YIN with easing the affected liver.All medicines share, and hit pathogenesis, specially do not relieve dizziness, high fever, infantile convulsions, epilepsy, etc. and wind stops certainly.
Preferably, the medicament be made up of the crude drug of following mass ratio of described treatment facial spasm Chinese medicine composition:
Semen Ziziphi Spinosae 14 ~ 16 parts, Ganoderma 2 ~ 4 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Schisandrae Chinensis 5 ~ 7 parts, the Radix Paeoniae Alba 28 ~ 32 parts, 9 ~ 11 parts, Fructus Mori, Flos Rosae Rugosae 5 ~ 7 parts, Fructus Tribuli 7 ~ 9 parts, Herba Equiseti Hiemalis 7 ~ 9 parts, Magnetitum 18 ~ 22 parts, succinum 1 ~ 3 part, 4 ~ 6 parts, Radix Glycyrrhizae.
Preferred further, the medicament that described treatment facial spasm Chinese medicine composition is made up of the crude drug of following mass ratio:
Semen Ziziphi Spinosae 15 parts, Ganoderma 3 parts, Rhizoma et radix valerianae 5 parts, Fructus Schisandrae Chinensis 6 parts, the Radix Paeoniae Alba 30 parts, 10 parts, Fructus Mori, Flos Rosae Rugosae 6 parts, Fructus Tribuli 8 parts, Herba Equiseti Hiemalis 8 parts, Magnetitum 20 parts, succinum 2 parts, 5 parts, Radix Glycyrrhizae.
Described treatment facial spasm Chinese medicine composition can adopt existing Chinese medicine preparation technology to be prepared into any conventional oral preparations, such as can decocting be adopted to obtain water decoction said components, by other existing Chinese medicine preparation technology, described treatment facial spasm Chinese medicine composition can also be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
compared with prior art, beneficial effect of the present invention
Treatment facial spasm Chinese medicine composition provided by the invention, look for another way from emotional disorder opinion and control facial spasm, stable curative effect, untoward reaction are few, easy to use, safe, are the special-purpose medicaments for the treatment of facial spasm.
one treats facial spasm Chinese medicine composition, and clinical efficacy is summed up
1 physical data
60 routine patients adopt random digits table that patient is divided into 2 groups at random, in treatment group 30 example, and man 11 example, female 19 example; ; Year at age (39.53 ± 6.78), individual month of the course of disease (6.16 ± 4.58).In matched group 30 example, man 7 example, female 23 example; Year at age (38.86 ± 6.91), individual month of the course of disease (5.89 ± 4.64).2 groups of physical data compare, and no significant difference (P > 0.05), has comparability.
2 diagnostic criterias
With reference to " practical neurological " (history Yuquan. practical neurological. Shanghai: Shanghai science tech publishing house, 1994:196.) in the diagnostic criteria of facial spasm: the paroxysmal of unknown cause, quick irregular facial spasm and without other nervous system positive sign person.
3 Therapeutic Method
The Chinese medicine composition water decoction of the oral the present invention's development for the treatment of group:
Semen Ziziphi Spinosae 15 grams, Ganoderma (grind into powder and take after mixing it with water) 3 grams, Rhizoma et radix valerianae 5 grams, Fructus Schisandrae Chinensis 6 grams, the Radix Paeoniae Alba 30 grams, 10 grams, Fructus Mori, Flos Rosae Rugosae 6 grams, Fructus Tribuli 8 grams, Herba Equiseti Hiemalis 8 grams, Magnetitum 20 grams, succinum (grind into powder and take after mixing it with water) 2 grams, 5 grams, Radix Glycyrrhizae, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Matched group oral carbamazepine 200 mg, every day three times.
4 therapeutic outcomes
4.1 criterions of therapeutical effect: reference literature [Samii M, Gunther T, Iaconetta G, et al.Microvascular de-compression to treat hemifacial spasm:long-term results fora consecutive series of 143 patients.Neurosurgery, 2002,50 (4): 712-719.] formulate.Spasm strength grading standard: 0 grade, without spasm; 1 grade, outside stimulus causes slight spasm; 2 grades, slight spasm, visible facial muscle twitches, nonfunctional obstacle; 3 grades, moderate spasm, facial spasm is obvious, has slight dysfunction; 4 grades, severe spasm, has severe dysfunction, affects work and life.Cure: transference cure, spasm is classified as 0 grade, without recurrence in March; Take a turn for the better: symptom obviously alleviates, and spasm frequency, amplitude all obviously reduce, spasm classification declines and is greater than more than 1 grade; Invalid: spasm classification does not decline, or rises on the contrary.
4.2 results: through treatment in 4 ~ 6 weeks, treatment group recovery from illness 12 example, take a turn for the better 15 examples, invalid 3 examples, and total effective rate is 90.00%; Matched group recovery from illness 8 example, take a turn for the better 16 examples, invalid 6 examples, and total effective rate is 80.00%; 2 groups of total effective rates compare, and difference has statistical significance (P < 0.05).Matched group has 6 routine patients and occurs the symptom such as dizziness, Nausea and vomiting, erythra, abdominal distention, blurred vision in various degree, and above-mentioned untoward reaction does not all appear in treatment group.2 groups of adverse reaction rates compare, and difference has statistical significance (P < 0.05).
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
Embodiment 1
One treats facial spasm Chinese medicine composition, by Semen Ziziphi Spinosae 18 grams, Ganoderma (grind into powder and take after mixing it with water) 4 grams, Rhizoma et radix valerianae 6 grams, Fructus Schisandrae Chinensis 8 grams, the Radix Paeoniae Alba 35 grams, 12 grams, Fructus Mori, Flos Rosae Rugosae 8 grams, Fructus Tribuli 10 grams, Herba Equiseti Hiemalis 10 grams, Magnetitum 25 grams, succinum (grind into powder and take after mixing it with water) 3 grams, 6 grams, Radix Glycyrrhizae, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 2
One treats facial spasm Chinese medicine composition, by Semen Ziziphi Spinosae 16 grams, Ganoderma (grind into powder and take after mixing it with water) 4 grams, Rhizoma et radix valerianae 6 grams, Fructus Schisandrae Chinensis 7 grams, the Radix Paeoniae Alba 32 grams, 11 grams, Fructus Mori, Flos Rosae Rugosae 7 grams, Fructus Tribuli 9 grams, Herba Equiseti Hiemalis 9 grams, Magnetitum 22 grams, succinum (grind into powder and take after mixing it with water) 3 grams, 6 grams, Radix Glycyrrhizae, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 3
One treats facial spasm Chinese medicine composition, by Semen Ziziphi Spinosae 15 grams, Ganoderma (grind into powder and take after mixing it with water) 3 grams, Rhizoma et radix valerianae 5 grams, Fructus Schisandrae Chinensis 6 grams, the Radix Paeoniae Alba 30 grams, 10 grams, Fructus Mori, Flos Rosae Rugosae 6 grams, Fructus Tribuli 8 grams, Herba Equiseti Hiemalis 8 grams, Magnetitum 20 grams, succinum (grind into powder and take after mixing it with water) 2 grams, 5 grams, Radix Glycyrrhizae, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 4
One treats facial spasm Chinese medicine composition, by Semen Ziziphi Spinosae 14 grams, Ganoderma (grind into powder and take after mixing it with water) 2 grams, Rhizoma et radix valerianae 4 grams, Fructus Schisandrae Chinensis 5 grams, the Radix Paeoniae Alba 28 grams, 9 grams, Fructus Mori, Flos Rosae Rugosae 5 grams, Fructus Tribuli 7 grams, Herba Equiseti Hiemalis 7 grams, Magnetitum 18 grams, succinum (grind into powder and take after mixing it with water) 1 gram, 4 grams, Radix Glycyrrhizae, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Embodiment 5
One treats facial spasm Chinese medicine composition, by Semen Ziziphi Spinosae 12 grams, Ganoderma (grind into powder and take after mixing it with water) 2 grams, Rhizoma et radix valerianae 4 grams, Fructus Schisandrae Chinensis 4 grams, the Radix Paeoniae Alba 25 grams, 8 grams, Fructus Mori, Flos Rosae Rugosae 4 grams, Fructus Tribuli 6 grams, Herba Equiseti Hiemalis 6 grams, Magnetitum 15 grams, succinum (grind into powder and take after mixing it with water) 1 gram, 4 grams, Radix Glycyrrhizae, conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
Claims (4)
1. treat a facial spasm Chinese medicine composition, it is characterized in that the medicament be made up of the crude drug of following mass ratio:
Semen Ziziphi Spinosae 12 ~ 18 parts, Ganoderma 2 ~ 4 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Schisandrae Chinensis 4 ~ 8 parts, the Radix Paeoniae Alba 25 ~ 35 parts, 8 ~ 12 parts, Fructus Mori, Flos Rosae Rugosae 4 ~ 8 parts, Fructus Tribuli 6 ~ 10 parts, Herba Equiseti Hiemalis 6 ~ 10 parts, Magnetitum 15 ~ 25 parts, succinum 1 ~ 3 part, 4 ~ 6 parts, Radix Glycyrrhizae.
2. treatment facial spasm Chinese medicine composition as claimed in claim 1, is characterized in that the medicament be made up of the crude drug of following mass ratio:
Semen Ziziphi Spinosae 14 ~ 16 parts, Ganoderma 2 ~ 4 parts, Rhizoma et radix valerianae 4 ~ 6 parts, Fructus Schisandrae Chinensis 5 ~ 7 parts, the Radix Paeoniae Alba 28 ~ 32 parts, 9 ~ 11 parts, Fructus Mori, Flos Rosae Rugosae 5 ~ 7 parts, Fructus Tribuli 7 ~ 9 parts, Herba Equiseti Hiemalis 7 ~ 9 parts, Magnetitum 18 ~ 22 parts, succinum 1 ~ 3 part, 4 ~ 6 parts, Radix Glycyrrhizae.
3. treatment facial spasm Chinese medicine composition as claimed in claim 1, is characterized in that the medicament be made up of the crude drug of following mass ratio:
Semen Ziziphi Spinosae 15 parts, Ganoderma 3 parts, Rhizoma et radix valerianae 5 parts, Fructus Schisandrae Chinensis 6 parts, the Radix Paeoniae Alba 30 parts, 10 parts, Fructus Mori, Flos Rosae Rugosae 6 parts, Fructus Tribuli 8 parts, Herba Equiseti Hiemalis 8 parts, Magnetitum 20 parts, succinum 2 parts, 5 parts, Radix Glycyrrhizae.
4. treat the preparation method of facial spasm Chinese medicine composition as claimed in claim 1, it is characterized in that the Chinese medicinal components of described mass ratio to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168882A (en) * | 2015-10-16 | 2015-12-23 | 朱云 | Traditional Chinese medicine nursing composition for treating wind-phlegm obstruction type hemi-facial spasm |
| CN105362770A (en) * | 2015-12-09 | 2016-03-02 | 徐冉 | Traditional Chinese medicine composition for treating facial spasm and preparation method |
| CN105617122A (en) * | 2016-04-06 | 2016-06-01 | 张立云 | Traditional Chinese medicine for treating wind-yang hyperactivity type prosopospasm |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060182794A1 (en) * | 2005-02-14 | 2006-08-17 | Pankaj Modi | Stabilized compositions for topical administration and methods of making same |
| CN101675972A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Blood-enriching tranquillizing traditional Chinese medicine composition |
-
2015
- 2015-01-05 CN CN201510001220.0A patent/CN104547131A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060182794A1 (en) * | 2005-02-14 | 2006-08-17 | Pankaj Modi | Stabilized compositions for topical administration and methods of making same |
| CN101675972A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Blood-enriching tranquillizing traditional Chinese medicine composition |
Non-Patent Citations (1)
| Title |
|---|
| 鲍远程: "《现代中医神经病学》", 30 September 2003, 人民卫生出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168882A (en) * | 2015-10-16 | 2015-12-23 | 朱云 | Traditional Chinese medicine nursing composition for treating wind-phlegm obstruction type hemi-facial spasm |
| CN105362770A (en) * | 2015-12-09 | 2016-03-02 | 徐冉 | Traditional Chinese medicine composition for treating facial spasm and preparation method |
| CN105617122A (en) * | 2016-04-06 | 2016-06-01 | 张立云 | Traditional Chinese medicine for treating wind-yang hyperactivity type prosopospasm |
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