CN101862382A - Pearl health care product for improving sleeping - Google Patents

Pearl health care product for improving sleeping Download PDF

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Publication number
CN101862382A
CN101862382A CN201010113948A CN201010113948A CN101862382A CN 101862382 A CN101862382 A CN 101862382A CN 201010113948 A CN201010113948 A CN 201010113948A CN 201010113948 A CN201010113948 A CN 201010113948A CN 101862382 A CN101862382 A CN 101862382A
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Prior art keywords
sleep
extract
health care
sleeping
extractive
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CN201010113948A
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Chinese (zh)
Inventor
周树立
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Hainan Jingrun Zhenzhu Biological Technology Co Ltd
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Hainan Jingrun Zhenzhu Biological Technology Co Ltd
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Priority to CN201010113948A priority Critical patent/CN101862382A/en
Publication of CN101862382A publication Critical patent/CN101862382A/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention belongs to the technical field of health care products, in particular to a pearl health care product for improving sleeping, which is prepared by uniformly mixing pearl powder, spina date seed extractive, American ginseng extractive, Griffonia extractive and VB6. The invention efficiently utilizes the active constituent of natural plant extractives, and has the functions of tranquilizing and allaying excitement, nourishing heart and clearing heat and relieving fidgetness, can prolong the sleeping duration time and has excellent function of improving sleeping.

Description

A kind of pearl health products with improvement sleep
Technical field
The invention belongs to health product technology field, relate to a kind of health product that are used to improve sleep, be specifically related to a kind of pearl health products that improves sleep that has.
Background technology
People's life has 1/3 to spend in sleep approximately, sleep is human basic psychological need, normal and comfortable sleep is brought many benefits to a people healthy: the first, sleep is the basic life style that the mankind depend on for existence, but its allaying tiredness regains one's strength; The second, promote growth promoter, slow down aging promotes longevity, helps beautifying skin; Three, enhancing immunity, the rehabilitation body; Four, the protection brain regains one's vigor.Sleep takes place that obstacle (can't fall asleep, sleep not deeply, interrupt easily or sleep quality bad etc.) causes on the health easily, many puzzlements mentally, low etc. as distractibility, memory variation, tired, flag, giddy, headache, mood, therefore sleep is the interested research topics of people at all times.
The 21 century enemy of human health maximum is " insomnia ", modern society's work rhythm anxiety, and people's pressure is big, and the sleep disorder problem is more and more outstanding, and the whole world has people's existence sleep disorder in various degree of 27% approximately.Insomnia is a kind of common disease of people, and the lighter has difficulty in going to sleep, or easily wakes up in the back of sleeping; Weight person can lie awake all night.Diseases such as the normal spiritedness of insomniac is depressed, fatigue and weak, dizziness, cardiopalmus, agitation.With the passing of time body function descends, and can cause the generation of multiple disease, has a strong impact on people's health, work and life.To insomnia's treatment, Western medicine adopts the sedative hypnotic more, and better effects is arranged, but certain drug resistance and dependency are arranged, and certain side effect is arranged, and liver, kidney, stomach are all had certain influence at present; Chinese patent medicine is commonly used Cinnabar Sedative Pill, Tianwang Buxin Dan, and wherein, Cinnabar Sedative Pill includes Cinnabaris, Rhizoma Coptidis, Radix Angelicae Sinensis, Radix Rehmanniae Preparata etc., and Tianwang Buxin Dan includes the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Codonopsis etc., and these medicine adaptive surfaces are narrower, and some patient's result of use is not good.
Summary of the invention
The purpose of this invention is to provide a kind of pearl health products that improves sleep that has, can effectively prolong sleep time, reduce the number of times of awakening every night, increase a day sleep total amount, thereby reach the effect of improving sleep.
The technical solution adopted in the present invention:
A kind of pearl health products with improvement sleep is by Margarita powder, Semen Ziziphi Spinosae extract, Radix Panacis Quinquefolii extract, JIANAGU extract and V B6Make through mix homogeneously, wherein each components contents is by weight percentage: Margarita powder 25~85%, Semen Ziziphi Spinosae extract 5~65%, Radix Panacis Quinquefolii extract 0.5~30%, JIANAGU extract 5~50%, V B60.05~2%.
Saponin in the Radix Panacis Quinquefolii can effectively strengthen nervus centralis, reach with all worries set aside with fixed attention, effects such as allaying tiredness, memory reinforcing, applicable to symptoms such as insomnia, irritated, hypomnesis and senile dementias; The calmness of Semen Ziziphi Spinosae extract tool, syngignoscism; The contained 5-hydroxyryptophan of JIANAGU extract (5-HTP) is a control human body emotion, the precursor substance of the nerve conduction thing-serotonin of sleep state, additional 5-HTP can make the serotonin concentration of brain raise, anti-melancholy symptom also can promote the concentration of brain melatonin simultaneously, effectively improves sleep naturally.
The health product of above-mentioned improvement sleep can be the dosage forms on any pharmaceutics.
Manufacture method of the present invention is: by above-mentioned prescription each component weighed, and mixing, packing.
The present invention confirms to improve the effect of sleeping through animal experiment, experimental result and conclusion:
1, to the influence of spontaneous activity
48 male and female half and half of mice are divided into four groups at random.High, medium and low dosage group of the present invention gives 10.0ml/kg, 5.0ml/kg, 2.5ml/kg respectively, matched group gives with the volume normal saline, continuous irrigation stomach 30d, 30min after the last administration, mice is put into spontaneous activity enumerator endoadaptation 5min, write down the means of activity of mice in the 5min then, as shown in table 1:
This health food of table 1 is to the influence of mice 5min spontaneous activity
Figure GSA00000020271800031
By table as seen: high dose group can obviously reduce the spontaneous activity number of times of mice, with matched group notable difference is arranged relatively.
2, to the pentobarbital sodium influence of the length of one's sleep
60 of mices, male female dual-purpose is divided into four groups at random.High, medium and low dosage group of the present invention gives 10.0ml/kg, 5.0ml/kg, 2.5ml/kg respectively, and matched group gives with the volume normal saline, continuous irrigation stomach 30d, 30min after the last administration, every group of mouse peritoneal injection pentobarbital sodium 40mg/kg, the length of one's sleep of record mice, as shown in table 2:
This health food of table 2 is to the pentobarbital sodium inducing mouse influence of the length of one's sleep (x ± SD)
Figure GSA00000020271800032
By table as seen: middle and high dosage group has been compared significant difference with the blank group.
3, the hypnosis of pentobarbital sodium sub-threshold dose is tested
60 of mices, male female dual-purpose is divided into four groups at random.High, medium and low dosage group of the present invention gives 10.0ml/kg, 5.0ml/kg, 2.5ml/kg respectively, matched group gives with the volume normal saline, continuous irrigation stomach 30d, 30min after the last administration, each treated animal lumbar injection pentobarbital sodium 30mg/kg, the number of animals (to be index more than the righting reflex loss 1min) that observation is slept to each group generation in the 30min behind the pentobarbital sodium, shown in table 3, table 4:
This health food of table 3 is to the influence of the sleeping incidence rate of pentobarbital sodium sub-threshold dose mice (x ± SD)
Figure GSA00000020271800041
By table as seen: significant difference is arranged with the blank group.
This health food of table 4 is to the preclinical influence of sleeping of mice pentobarbital sodium
By table as seen: significant difference is arranged with the blank group.
4, conclusion: to improving the criterion of sleep function health food, can determine that this health food zoopery result has the function of improving sleep according to " health food check and assessment technique standard " (2003 editions).
The present invention effectively utilizes the effective ingredient of natural plant extracts, has the effect of tranquillizing and allaying excitement, the heart nourishing and intellengence improving, clearing heat and relieving fidgetness, can effectively prolong sleep time, reduce the number of times of awakening every night, increase a day sleep total amount, ensure sleep quality, have the effect of good improvement sleep.
Specific embodiments
The invention will be further described with indefiniteness embodiment below.
Embodiment one
Get Margarita powder 500g, Semen Ziziphi Spinosae extract (12 times of water extraction) 100g, Radix Panacis Quinquefolii extract (10 times of water extraction) 50g, V B65g, JIANAGU extract 100g, the mixer mix homogeneously is filled with capsule filling machine, and capsule is 1#, and loading 0.3g/ grain makes 2000 altogether.
Embodiment two
Get Margarita powder 500g, Semen Ziziphi Spinosae extract (12 times of water extraction) 300g, Radix Panacis Quinquefolii extract (10 times of water extraction) 100g, V B610g, JIANAGU extract 150g, the mixer mix homogeneously is filled with capsule filling machine, and capsule is 1#, and loading 0.3g/ grain makes 2800 altogether.

Claims (1)

1. one kind has the pearl health products that improves sleep, is by Margarita powder, Semen Ziziphi Spinosae extract, Radix Panacis Quinquefolii extract, JIANAGU extract and V B6Make through mix homogeneously, wherein each components contents is by weight percentage: Margarita powder 25~85%, Semen Ziziphi Spinosae extract 5~65%, Radix Panacis Quinquefolii extract 0.5~30%, JIANAGU extract 5~50%, V B60.05~2%.
CN201010113948A 2010-01-21 2010-01-21 Pearl health care product for improving sleeping Pending CN101862382A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201010113948A CN101862382A (en) 2010-01-21 2010-01-21 Pearl health care product for improving sleeping

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201010113948A CN101862382A (en) 2010-01-21 2010-01-21 Pearl health care product for improving sleeping

Publications (1)

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CN101862382A true CN101862382A (en) 2010-10-20

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107960469A (en) * 2017-09-13 2018-04-27 陕西理工大学 A kind of pearl milk powder for improving sleep and preparation method thereof
CN110898081A (en) * 2019-10-29 2020-03-24 广东医科大学 External massage preparation with functions of helping sleep and beautifying skin

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107960469A (en) * 2017-09-13 2018-04-27 陕西理工大学 A kind of pearl milk powder for improving sleep and preparation method thereof
CN110898081A (en) * 2019-10-29 2020-03-24 广东医科大学 External massage preparation with functions of helping sleep and beautifying skin

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Open date: 20101020