CN101848908B - 激酶抑制剂的组合物及其在治疗癌症和其它与激酶相关的疾病中的用途 - Google Patents

激酶抑制剂的组合物及其在治疗癌症和其它与激酶相关的疾病中的用途 Download PDF

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CN101848908B
CN101848908B CN200880114705.9A CN200880114705A CN101848908B CN 101848908 B CN101848908 B CN 101848908B CN 200880114705 A CN200880114705 A CN 200880114705A CN 101848908 B CN101848908 B CN 101848908B
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heterocycle
alkyl
aryl
cycloalkyl
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CN101848908A (zh
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李嘉强
刘继峰
李有志
李伟
H·罗格夫
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1Globe Biomedical Co Ltd
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Boston Biomedical Inc
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CN200880114705.9A 2007-09-06 2008-09-05 激酶抑制剂的组合物及其在治疗癌症和其它与激酶相关的疾病中的用途 Active CN101848908B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US97041007P 2007-09-06 2007-09-06
US60/970,410 2007-09-06
US1338907P 2007-12-13 2007-12-13
US61/013,389 2007-12-13
US7429508P 2008-06-20 2008-06-20
US61/074,295 2008-06-20
PCT/US2008/075418 WO2009033033A2 (en) 2007-09-06 2008-09-05 Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases

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CN101848908A CN101848908A (zh) 2010-09-29
CN101848908B true CN101848908B (zh) 2014-07-02

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WO2009033033A2 (en) * 2007-09-06 2009-03-12 Boston Biomedical, Inc. Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases
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ES2609459T3 (es) 2012-08-23 2017-04-20 The Institute Of Cancer Research : The Royal Cancer Hospital Compuestos heterocíclicos condensados y su uso
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CA2904152A1 (en) * 2013-03-13 2014-10-02 Boston Biomedical, Inc. 3-(aryl or heteroaryl) methyleneindolin-2-one derivatives as inhibitors of cancer stem cell pathway kinases for the treatment of cancer
US9187454B2 (en) 2013-03-13 2015-11-17 Boston Biomedical, Inc. Inhibitors of kinases and cancer stem cells, and methods of preparation and use thereof
EP3010903A1 (en) * 2013-06-20 2016-04-27 Boehringer Ingelheim International GmbH Olefin substituted oxindoles having ampk activity
TW201609094A (zh) * 2014-01-27 2016-03-16 波士頓生醫公司 治療癌症之新穎方法
WO2016057931A1 (en) 2014-10-10 2016-04-14 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration
US20180250261A1 (en) 2015-04-27 2018-09-06 Boston Biomedical, Inc. Method for treating cancer with a stat3 pathway inhibitor and kinase inhibitor
WO2017026119A1 (ja) * 2015-08-10 2017-02-16 大日本住友製薬株式会社 ５－（チアゾール－４－イル）インドリン－２－オン誘導体の精製方法
WO2017160978A1 (en) 2016-03-15 2017-09-21 Boston Biomedical, Inc. Cell cultures and use thereof
CA3029596A1 (en) 2016-06-28 2018-01-04 Boston Biomedical, Inc. Methods for treating cancer
WO2018098352A2 (en) 2016-11-22 2018-05-31 Jun Oishi Targeting kras induced immune checkpoint expression
US11299469B2 (en) 2016-11-29 2022-04-12 Sumitomo Dainippon Pharma Oncology, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
SG11202102684VA (en) 2018-09-18 2021-04-29 1 Globe Biomedical Co Ltd Treatment for non-alcoholic fatty liver disease
CN112996507B (zh) * 2018-09-18 2023-09-05 北京强新生物科技有限公司 肥胖症的治疗
IL312506A (en) 2021-11-08 2024-07-01 Progentos Therapeutics Inc Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof

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WO2009033033A2 (en) 2009-03-12
HK1148529A1 (en) 2011-09-09
LT2197878T (lt) 2016-09-26
US20180022743A1 (en) 2018-01-25
PL2197878T3 (pl) 2017-01-31
JP2019070051A (ja) 2019-05-09
US20100285006A1 (en) 2010-11-11
SI2197878T1 (sl) 2016-10-28
CN101848908A (zh) 2010-09-29
WO2009033033A3 (en) 2009-04-30
JP5974124B2 (ja) 2016-08-23
US9725444B2 (en) 2017-08-08
JP2010538091A (ja) 2010-12-09
US8299106B2 (en) 2012-10-30
US20190248781A1 (en) 2019-08-15
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HRP20161114T1 (hr) 2016-11-04
PT2197878T (pt) 2016-11-04
HUE030774T2 (hu) 2017-05-29
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