CN101835800A - 基于sdf-1的糖胺聚糖拮抗物及其使用方法 - Google Patents

基于sdf-1的糖胺聚糖拮抗物及其使用方法 Download PDF

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Publication number
CN101835800A
CN101835800A CN200880113405A CN200880113405A CN101835800A CN 101835800 A CN101835800 A CN 101835800A CN 200880113405 A CN200880113405 A CN 200880113405A CN 200880113405 A CN200880113405 A CN 200880113405A CN 101835800 A CN101835800 A CN 101835800A
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CN
China
Prior art keywords
sdf
amino acid
mutein
protein
lys
Prior art date
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Pending
Application number
CN200880113405A
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English (en)
Chinese (zh)
Inventor
安德烈亚斯·孔格尔
艾萨·沃纳
贾森·斯林斯比
西米·阿利
约翰·A·柯比
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Protaffin Biotechnologie AG
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Protaffin Biotechnologie AG
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Filing date
Publication date
Application filed by Protaffin Biotechnologie AG filed Critical Protaffin Biotechnologie AG
Publication of CN101835800A publication Critical patent/CN101835800A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN200880113405A 2007-10-24 2008-10-23 基于sdf-1的糖胺聚糖拮抗物及其使用方法 Pending CN101835800A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07450189.1 2007-10-24
EP07450189A EP2053060A1 (en) 2007-10-24 2007-10-24 SDF-1-based glyocosaminoglycan antagonists and methods of using same
PCT/EP2008/008960 WO2009053064A1 (en) 2007-10-24 2008-10-23 Sdf-1-based glycosaminoglycan antagonists and methods of using same

Publications (1)

Publication Number Publication Date
CN101835800A true CN101835800A (zh) 2010-09-15

Family

ID=39133777

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880113405A Pending CN101835800A (zh) 2007-10-24 2008-10-23 基于sdf-1的糖胺聚糖拮抗物及其使用方法

Country Status (13)

Country Link
US (1) US20100298203A1 (enExample)
EP (2) EP2053060A1 (enExample)
JP (1) JP2011501675A (enExample)
KR (1) KR20100085041A (enExample)
CN (1) CN101835800A (enExample)
AU (1) AU2008315614A1 (enExample)
BR (1) BRPI0818009A2 (enExample)
CA (1) CA2702502A1 (enExample)
EA (1) EA201000688A1 (enExample)
IL (1) IL205300A0 (enExample)
MX (1) MX2010004025A (enExample)
NZ (1) NZ584278A (enExample)
WO (1) WO2009053064A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102094043A (zh) * 2010-11-23 2011-06-15 山东农业大学 重组猪趋化因子cxcl12哺乳动物细胞表达质粒的构建与应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201200470A1 (ru) * 2009-09-11 2012-08-30 Протаффин Биотехнологие Аг Композиция для лечения опосредуемого cxcl8 воспаления легкого
EP2686344A1 (en) 2011-03-16 2014-01-22 Protaffin Biotechnologie AG Fgfr1-based antagonists with improved glycosaminoglycan affinity and methods of using same
WO2013007704A2 (en) 2011-07-08 2013-01-17 Protaffin Biotechnologie Ag Novel sdf-1-based glycosaminoglycan antagonist and methods of using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364894A (en) * 1993-03-31 1994-11-15 Tremco, Inc. Emulsification of asphalt and modified asphalt with primary emulsifier polymers comprised of acrylic acid type monomers
JP2000507596A (ja) * 1996-04-02 2000-06-20 プロジェニクス・ファーマスーティカルス・インコーポレーテッド Ｃｄ４▲上＋▼細胞のｈｉｖ―１感染を防ぐ方法
AU5811001A (en) * 2000-05-09 2001-11-20 Univ British Columbia Cxcr4 antagonist treatment of hematopoietic cells
WO2004094465A2 (en) * 2003-04-23 2004-11-04 The Board Of Trustees Of The University Of Illinois Office Of Technology Management University Of Illinois At Urbana-Champaign Synthetic molecules that mimic chemokines
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
US7662221B2 (en) * 2006-06-23 2010-02-16 Johns Manville Spray applied building wrap coating material, spray applied building wrap, and building construction assembly
AT504685B1 (de) * 2006-12-20 2009-01-15 Protaffin Biotechnologie Ag Fusionsproteine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102094043A (zh) * 2010-11-23 2011-06-15 山东农业大学 重组猪趋化因子cxcl12哺乳动物细胞表达质粒的构建与应用
CN102094043B (zh) * 2010-11-23 2012-11-07 山东农业大学 猪趋化因子cxcl12基因及其应用

Also Published As

Publication number Publication date
WO2009053064A8 (en) 2009-07-16
JP2011501675A (ja) 2011-01-13
BRPI0818009A2 (pt) 2015-04-14
IL205300A0 (en) 2010-12-30
MX2010004025A (es) 2010-04-30
EP2053060A1 (en) 2009-04-29
NZ584278A (en) 2012-06-29
EA201000688A1 (ru) 2010-10-29
US20100298203A1 (en) 2010-11-25
AU2008315614A1 (en) 2009-04-30
CA2702502A1 (en) 2009-04-30
EP2203473A1 (en) 2010-07-07
WO2009053064A1 (en) 2009-04-30
KR20100085041A (ko) 2010-07-28

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Effective date of abandoning: 20100915

C20 Patent right or utility model deemed to be abandoned or is abandoned