CA2702502A1 - Sdf-1-based glycosaminoglycan antagonists and methods of using same - Google Patents

Sdf-1-based glycosaminoglycan antagonists and methods of using same Download PDF

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Publication number
CA2702502A1
CA2702502A1 CA2702502A CA2702502A CA2702502A1 CA 2702502 A1 CA2702502 A1 CA 2702502A1 CA 2702502 A CA2702502 A CA 2702502A CA 2702502 A CA2702502 A CA 2702502A CA 2702502 A1 CA2702502 A1 CA 2702502A1
Authority
CA
Canada
Prior art keywords
sdf
amino acids
mutant protein
protein according
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2702502A
Other languages
English (en)
French (fr)
Inventor
Andreas Kungl
Isa Werner
Jason Slingsby
Simi Ali
John A. Kirby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protaffin Biotechnologie AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2702502A1 publication Critical patent/CA2702502A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/522Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2702502A 2007-10-24 2008-10-23 Sdf-1-based glycosaminoglycan antagonists and methods of using same Abandoned CA2702502A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07450189.1 2007-10-24
EP07450189A EP2053060A1 (en) 2007-10-24 2007-10-24 SDF-1-based glyocosaminoglycan antagonists and methods of using same
PCT/EP2008/008960 WO2009053064A1 (en) 2007-10-24 2008-10-23 Sdf-1-based glycosaminoglycan antagonists and methods of using same

Publications (1)

Publication Number Publication Date
CA2702502A1 true CA2702502A1 (en) 2009-04-30

Family

ID=39133777

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2702502A Abandoned CA2702502A1 (en) 2007-10-24 2008-10-23 Sdf-1-based glycosaminoglycan antagonists and methods of using same

Country Status (13)

Country Link
US (1) US20100298203A1 (enExample)
EP (2) EP2053060A1 (enExample)
JP (1) JP2011501675A (enExample)
KR (1) KR20100085041A (enExample)
CN (1) CN101835800A (enExample)
AU (1) AU2008315614A1 (enExample)
BR (1) BRPI0818009A2 (enExample)
CA (1) CA2702502A1 (enExample)
EA (1) EA201000688A1 (enExample)
IL (1) IL205300A0 (enExample)
MX (1) MX2010004025A (enExample)
NZ (1) NZ584278A (enExample)
WO (1) WO2009053064A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201200470A1 (ru) * 2009-09-11 2012-08-30 Протаффин Биотехнологие Аг Композиция для лечения опосредуемого cxcl8 воспаления легкого
CN102094043B (zh) * 2010-11-23 2012-11-07 山东农业大学 猪趋化因子cxcl12基因及其应用
EP2686344A1 (en) 2011-03-16 2014-01-22 Protaffin Biotechnologie AG Fgfr1-based antagonists with improved glycosaminoglycan affinity and methods of using same
WO2013007704A2 (en) 2011-07-08 2013-01-17 Protaffin Biotechnologie Ag Novel sdf-1-based glycosaminoglycan antagonist and methods of using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364894A (en) * 1993-03-31 1994-11-15 Tremco, Inc. Emulsification of asphalt and modified asphalt with primary emulsifier polymers comprised of acrylic acid type monomers
JP2000507596A (ja) * 1996-04-02 2000-06-20 プロジェニクス・ファーマスーティカルス・インコーポレーテッド Cd4▲上+▼細胞のhiv―1感染を防ぐ方法
AU5811001A (en) * 2000-05-09 2001-11-20 Univ British Columbia Cxcr4 antagonist treatment of hematopoietic cells
WO2004094465A2 (en) * 2003-04-23 2004-11-04 The Board Of Trustees Of The University Of Illinois Office Of Technology Management University Of Illinois At Urbana-Champaign Synthetic molecules that mimic chemokines
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
US7662221B2 (en) * 2006-06-23 2010-02-16 Johns Manville Spray applied building wrap coating material, spray applied building wrap, and building construction assembly
AT504685B1 (de) * 2006-12-20 2009-01-15 Protaffin Biotechnologie Ag Fusionsproteine

Also Published As

Publication number Publication date
WO2009053064A8 (en) 2009-07-16
CN101835800A (zh) 2010-09-15
JP2011501675A (ja) 2011-01-13
BRPI0818009A2 (pt) 2015-04-14
IL205300A0 (en) 2010-12-30
MX2010004025A (es) 2010-04-30
EP2053060A1 (en) 2009-04-29
NZ584278A (en) 2012-06-29
EA201000688A1 (ru) 2010-10-29
US20100298203A1 (en) 2010-11-25
AU2008315614A1 (en) 2009-04-30
EP2203473A1 (en) 2010-07-07
WO2009053064A1 (en) 2009-04-30
KR20100085041A (ko) 2010-07-28

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130903

FZDE Discontinued

Effective date: 20151023