AU2008315614A1 - SDF-1-based glycosaminoglycan antagonists and methods of using same - Google Patents

SDF-1-based glycosaminoglycan antagonists and methods of using same Download PDF

Info

Publication number
AU2008315614A1
AU2008315614A1 AU2008315614A AU2008315614A AU2008315614A1 AU 2008315614 A1 AU2008315614 A1 AU 2008315614A1 AU 2008315614 A AU2008315614 A AU 2008315614A AU 2008315614 A AU2008315614 A AU 2008315614A AU 2008315614 A1 AU2008315614 A1 AU 2008315614A1
Authority
AU
Australia
Prior art keywords
sdf
amino acids
mutant protein
protein according
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008315614A
Other languages
English (en)
Inventor
Simi Ali
John A. Kirby
Andreas Kungl
Jason Slingsby
Isa Werner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protaffin Biotechnologie AG
Original Assignee
Protaffin Biotechnologie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protaffin Biotechnologie AG filed Critical Protaffin Biotechnologie AG
Publication of AU2008315614A1 publication Critical patent/AU2008315614A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2008315614A 2007-10-24 2008-10-23 SDF-1-based glycosaminoglycan antagonists and methods of using same Abandoned AU2008315614A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07450189.1 2007-10-24
EP07450189A EP2053060A1 (en) 2007-10-24 2007-10-24 SDF-1-based glyocosaminoglycan antagonists and methods of using same
PCT/EP2008/008960 WO2009053064A1 (en) 2007-10-24 2008-10-23 Sdf-1-based glycosaminoglycan antagonists and methods of using same

Publications (1)

Publication Number Publication Date
AU2008315614A1 true AU2008315614A1 (en) 2009-04-30

Family

ID=39133777

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008315614A Abandoned AU2008315614A1 (en) 2007-10-24 2008-10-23 SDF-1-based glycosaminoglycan antagonists and methods of using same

Country Status (13)

Country Link
US (1) US20100298203A1 (enExample)
EP (2) EP2053060A1 (enExample)
JP (1) JP2011501675A (enExample)
KR (1) KR20100085041A (enExample)
CN (1) CN101835800A (enExample)
AU (1) AU2008315614A1 (enExample)
BR (1) BRPI0818009A2 (enExample)
CA (1) CA2702502A1 (enExample)
EA (1) EA201000688A1 (enExample)
IL (1) IL205300A0 (enExample)
MX (1) MX2010004025A (enExample)
NZ (1) NZ584278A (enExample)
WO (1) WO2009053064A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201200470A1 (ru) * 2009-09-11 2012-08-30 Протаффин Биотехнологие Аг Композиция для лечения опосредуемого cxcl8 воспаления легкого
CN102094043B (zh) * 2010-11-23 2012-11-07 山东农业大学 猪趋化因子cxcl12基因及其应用
EP2686344A1 (en) 2011-03-16 2014-01-22 Protaffin Biotechnologie AG Fgfr1-based antagonists with improved glycosaminoglycan affinity and methods of using same
WO2013007704A2 (en) 2011-07-08 2013-01-17 Protaffin Biotechnologie Ag Novel sdf-1-based glycosaminoglycan antagonist and methods of using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364894A (en) * 1993-03-31 1994-11-15 Tremco, Inc. Emulsification of asphalt and modified asphalt with primary emulsifier polymers comprised of acrylic acid type monomers
JP2000507596A (ja) * 1996-04-02 2000-06-20 プロジェニクス・ファーマスーティカルス・インコーポレーテッド Ｃｄ４▲上＋▼細胞のｈｉｖ―１感染を防ぐ方法
AU5811001A (en) * 2000-05-09 2001-11-20 Univ British Columbia Cxcr4 antagonist treatment of hematopoietic cells
WO2004094465A2 (en) * 2003-04-23 2004-11-04 The Board Of Trustees Of The University Of Illinois Office Of Technology Management University Of Illinois At Urbana-Champaign Synthetic molecules that mimic chemokines
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
US7662221B2 (en) * 2006-06-23 2010-02-16 Johns Manville Spray applied building wrap coating material, spray applied building wrap, and building construction assembly
AT504685B1 (de) * 2006-12-20 2009-01-15 Protaffin Biotechnologie Ag Fusionsproteine

Also Published As

Publication number Publication date
WO2009053064A8 (en) 2009-07-16
CN101835800A (zh) 2010-09-15
JP2011501675A (ja) 2011-01-13
BRPI0818009A2 (pt) 2015-04-14
IL205300A0 (en) 2010-12-30
MX2010004025A (es) 2010-04-30
EP2053060A1 (en) 2009-04-29
NZ584278A (en) 2012-06-29
EA201000688A1 (ru) 2010-10-29
US20100298203A1 (en) 2010-11-25
CA2702502A1 (en) 2009-04-30
EP2203473A1 (en) 2010-07-07
WO2009053064A1 (en) 2009-04-30
KR20100085041A (ko) 2010-07-28

Similar Documents

Publication Publication Date Title
Morla et al. A fibronectin self-assembly site involved in fibronectin matrix assembly: reconstruction in a synthetic peptide.
Czaplewski et al. Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1α, MIP-1β, and RANTES: characterization of active disaggregated chemokine variants
JP7028775B2 (ja) Ｆｇｆ２１変異体
US7541435B2 (en) Antagonists of cxcr3-binding cxc chemokines
US7740833B2 (en) Therapeutic uses of chemokine variants
US7425324B2 (en) Antagonists of MCP proteins
AU2008315614A1 (en) SDF-1-based glycosaminoglycan antagonists and methods of using same
Sebollela et al. Heparin-binding sites in granulocyte-macrophage colony-stimulating factor: localization and regulation by histidine ionization
AU2002358144B2 (en) Chemokine mutants acting as chemokine antagonists
SK287523B6 (sk) Použitie CC chemokínového mutanta, farmaceutický prostriedok s obsahom chemokínového mutanta, skrátený a mutovaný humánny RANTES a spôsob jeho výroby
EP2687537A1 (en) Polypeptide drug against hepatitis b virus x protein
AU2003302755B2 (en) Use of CC-chemokine mutants against liver diseases
EP1673388B1 (en) Cxcl8 antagonists
WO2013007704A2 (en) Novel sdf-1-based glycosaminoglycan antagonist and methods of using same
US20070016967A1 (en) Novel IFNgamma-like polypeptides

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted