CN101829035B - Hair nourishing pepper liquid for pepper and preparation method thereof - Google Patents
Hair nourishing pepper liquid for pepper and preparation method thereof Download PDFInfo
- Publication number
- CN101829035B CN101829035B CN201010127730XA CN201010127730A CN101829035B CN 101829035 B CN101829035 B CN 101829035B CN 201010127730X A CN201010127730X A CN 201010127730XA CN 201010127730 A CN201010127730 A CN 201010127730A CN 101829035 B CN101829035 B CN 101829035B
- Authority
- CN
- China
- Prior art keywords
- accounts
- hair nourishing
- pericarpium zanthoxyli
- oil
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000004209 hair Anatomy 0.000 title claims abstract description 37
- 239000007788 liquid Substances 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 235000002566 Capsicum Nutrition 0.000 title abstract 6
- 239000006002 Pepper Substances 0.000 title abstract 6
- 241000722363 Piper Species 0.000 title abstract 6
- 235000016761 Piper aduncum Nutrition 0.000 title abstract 6
- 235000017804 Piper guineense Nutrition 0.000 title abstract 6
- 235000008184 Piper nigrum Nutrition 0.000 title abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 48
- 238000003756 stirring Methods 0.000 claims abstract description 26
- 239000000341 volatile oil Substances 0.000 claims abstract description 24
- 239000000284 extract Substances 0.000 claims abstract description 22
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 18
- 229940119170 jojoba wax Drugs 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000002904 solvent Substances 0.000 claims abstract description 12
- 238000001914 filtration Methods 0.000 claims abstract description 8
- 239000012530 fluid Substances 0.000 claims abstract description 8
- 244000178231 Rosmarinus officinalis Species 0.000 claims abstract description 4
- 239000003921 oil Substances 0.000 claims description 21
- 241000628997 Flos Species 0.000 claims description 18
- 241001529742 Rosmarinus Species 0.000 claims description 17
- 238000004090 dissolution Methods 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 6
- 238000005406 washing Methods 0.000 claims description 6
- 238000005303 weighing Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- 238000000605 extraction Methods 0.000 claims 1
- 201000004384 Alopecia Diseases 0.000 abstract description 21
- 231100000360 alopecia Toxicity 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 7
- 206010001766 Alopecia totalis Diseases 0.000 abstract description 4
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 2
- 241000382455 Angelica sinensis Species 0.000 abstract 2
- 235000007866 Chamaemelum nobile Nutrition 0.000 abstract 2
- 244000042664 Matricaria chamomilla Species 0.000 abstract 2
- 235000007232 Matricaria chamomilla Nutrition 0.000 abstract 2
- 244000273928 Zingiber officinale Species 0.000 abstract 2
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 2
- 229940116229 borneol Drugs 0.000 abstract 2
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 2
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 2
- 235000008397 ginger Nutrition 0.000 abstract 2
- 235000013305 food Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 11
- 241001465754 Metazoa Species 0.000 description 9
- 210000004761 scalp Anatomy 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 210000003491 skin Anatomy 0.000 description 7
- 239000000126 substance Substances 0.000 description 6
- 206010040880 Skin irritation Diseases 0.000 description 4
- 230000036556 skin irritation Effects 0.000 description 4
- 231100000475 skin irritation Toxicity 0.000 description 4
- 241000699666 Mus <mouse, genus> Species 0.000 description 3
- 241000221095 Simmondsia Species 0.000 description 3
- 235000004433 Simmondsia californica Nutrition 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 3
- 231100000460 acute oral toxicity Toxicity 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 101100011509 Drosophila melanogaster Baldspot gene Proteins 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 208000005374 Poisoning Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000003779 hair growth Effects 0.000 description 2
- 208000024963 hair loss Diseases 0.000 description 2
- 230000003676 hair loss Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 231100000572 poisoning Toxicity 0.000 description 2
- 230000000607 poisoning effect Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 101100008047 Caenorhabditis elegans cut-3 gene Proteins 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010016936 Folliculitis Diseases 0.000 description 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 description 1
- 201000001880 Sexual dysfunction Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 208000004631 alopecia areata Diseases 0.000 description 1
- 239000003098 androgen Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000003659 hair regrowth Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 231100000872 sexual dysfunction Toxicity 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Abstract
The invention discloses hair nourishing pepper liquid and a preparation method thereof. The preparation method mainly comprises the following steps of: taking the extracts of raw materials including pharmaceutical/food pepper, cacumen biotae, angelica sinensis, ginger and fructus cnidii; filtering the extracts and vacuum condensing to obtain fluid extract; adding the fluid extract, borneol, jojoba oil, rosemary essential oil and chamomile essential oil into the rest water of the formula, stirring uniformly and filtering to obtain the product. The hair nourishing pepper liquid comprise the following raw materials in percentage by weight: 5% to 8% of pepper, 5% to 8% of cacumen biotae, 3% to 6% of angelica sinensis, 3% to 6% of ginger, 3% to 6% of fructus cnidii, 1% to 2% of borneol, 2% to 5% of jojoba oil, 1% to 3% of rosemary essential oil, 1% to 3% of chamomile essential oil, 5% to 10% of solubilizer, 10% to 15% of ethanol and the balance of water. The hair nourishing liquid has obvious curative effect in preventing and treating bald spots, alopecia totalis, seborrheic alopecia, alopecia after illness and simplex alopecia.
Description
One, technical field
The present invention relates to a kind of daily-use chemical industry articles for use, particularly a kind of is the hair nourishing liquid and preparation method thereof of main active with the Pericarpium Zanthoxyli.
Two, background technology
According to statistics, in 25 years old～35 years old man of China, have 40% people to suffer from alopecia in various degree approximately, total number of persons surpasses 1.5 hundred million; Also very many of the people of alopecia abroad, for example Japanese hair loss patient has 2,000 ten thousand people approximately; The U.S. has 3,500 ten thousand people approximately; France's hair loss patient accounts for 2% of population.The problem of the alopecia problem that become international is so prevention and treatment alopecia also become the problem of whole world medical profession and the concern of daily use chemicals circle.Therefore, the medicine of various at home and abroad treatment alopecias is with to educate the daily chemical products of sending out also fashionable thereupon.
But, educate the propaganda materials of each company of sending out product according to the production of collecting, the existing anti-alopecia product of China with educate that to send out a product major part all be to add the Chinese herbal medicine product.They all exist oneself advantage and deficiency separately, but generally speaking, and the effect of oozing of Chinese medicine preparation onset long action time, skin is slow, and what have does not even play the hair regrowth in the propaganda.And doctor trained in Western medicine is used chemotherapy more; Usually use hormone or use the Drug therapy of resisting androgen secretion; Really can play comparatively significantly curative effect in a short time; But inevitably produce some side effect, in case the phenomenon that also possibly have a rebound after the drug deactivated also can produce side effect such as cardiovascular disease, sexual dysfunction after some Western medicine is taken for a long time.
Three, summary of the invention
The purpose of this invention is to provide a kind of Pericarpium Zanthoxyli hair nourishing liquid; Be with Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens; The raw extract of Fructus Cnidii is a Main Ingredients and Appearance; Being equipped with Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil is raw material, makes up the hair nourishing liquid of processing in the proper ratio, and prevention and treatment bald spot, alopecia totalis, seborrheic alopecia, the alopecia of the simple property of post disease alopecia are had tangible curative effect.
Concrete technical scheme is:
A kind of Pericarpium Zanthoxyli hair nourishing liquid is mainly by Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, and the raw extract of Fructus Cnidii and Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil are formed, and its percentage by weight is: Pericarpium Zanthoxyli accounts for 5%～8% of total amount; Cacumen Platycladi accounts for 5%～8%, and Radix Angelicae Sinensis accounts for 3%～6%, and Rhizoma Zingiberis Recens accounts for 3%～6%; Fructus Cnidii accounts for 3%～6%, and Borneolum Syntheticum accounts for 1%～2%, and Jojoba oil accounts for 2%～5%; Rosemary ethereal oil accounts for 1%～3%, and the Flos Matricariae chamomillae quintessence oil accounts for 1%～3%, and solubilizing agent accounts for 5%～10%; 65% ethanol accounts for 10%～15%, and surplus is a pure water.
The method for preparing of above-mentioned Pericarpium Zanthoxyli hair nourishing liquid is characterized in that, comprises the following steps:
1) at first take by weighing Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens by the hair nourishing liquid composition of raw materials of claim 1, Fructus Cnidii, washing, oven dry mixes, and pulverizes, and joins in the extractor after crossing 10 mesh sieves:
2) 65% ethanol of 10 times of amounts of adding above-mentioned raw materials in extractor stirs under 60 ℃ ± 5 ℃ conditions and extracted 2～4 hours, filters; Keep filtrating, in filtering residue, add 65% ethanol of 6 times of material quantities then again, carry out the second time by above-mentioned process conditions and extract; Filter, merge filtrating twice;
The filtrating that 3) will obtain is carried out concentrating under reduced pressure, gets fluid extract;
4) get the Borneolum Syntheticum and 65% ethanol of formula ratio, under 40 ℃ ± 5 ℃ conditions, stir and make its abundant mixed dissolution, subsequent use;
5) get Jojoba oil, rosemary ethereal oil, Flos Matricariae chamomillae quintessence oil and the solubilizing agent of formula ratio, stir at ambient temperature and make its abundant mixed dissolution, subsequent use;
6) with 3) 4) 5) add in the water of prescription surplus, stir, filter, promptly get the Pericarpium Zanthoxyli hair nourishing liquid.
The Chinese medicine that the present invention adopts is the raw material of medicine-food two-purpose mostly; Harmless to human body skin; Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, the raw extract of Fructus Cnidii and Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil organic synthesis have following technical characterstic:
1, contains hair nourishing agent.High-nutrient such as Jojoba oil, Radix Angelicae Sinensis mass-energy is that hair growth provides prescribing adequate nutrition;
2, contain the hair stimulant.Rhizoma Zingiberis Recens and rosemary ethereal oil equalenergy stimulus scalp and root of hair can promote scalp blood circulation and scalp metabolism, strengthen the function that hair follicle is carried nutrition;
3, contain skin penetrant.Borneolum Syntheticum and plants essential oil can be strengthened the infiltration to scalp of medicine and nutrient substance, promote absorption and the utilization of scalp cells to medicine and nutrient substance.
4, contain the skin sterilization agent.Contain the various sterilization agent in this hair nourishing liquid, have bactericidal antiphlogistic and itching-relieving action like raw materials such as Pericarpium Zanthoxyli, Cacumen Platycladi, Fructus Cnidiis;
5, contain Radix Angelicae Sinensis, can " regulating menstruation and nourishing blood ", can strengthen blood circulation, promote medicine and nutrient substance transportation, promote hair growth;
Show through clinical experiment: Pericarpium Zanthoxyli hair nourishing liquid of the present invention reaches more than 98% the total effective rate of bald spot, alopecia totalis, seborrheic alopecia, the alopecia of the simple property of post disease alopecia.
1, acute oral toxicity test:
Tried thing: get Pericarpium Zanthoxyli hair nourishing liquid 7.0ml adding distil water to 20ml, stir, subsequent use, this Pericarpium Zanthoxyli hair nourishing liquid is a dark brown liquid, proportion 0.892.
Experimental animal: 20 of Kunming kind white mice, female, hero half and half, body weight 18～22g, one-level animal (No. the 08th～024, the moving card of doctor word) are provided by Shaanxi Province academy of traditional Chinese medicine experimental animal center.The Animal House quality certification number: the moving word of doctor 08-32 number.Animal feed, beverage are provided by Shaanxi Province academy of traditional Chinese medicine experimental animal center.
Animal housing's environment: temperature: 18～22 ℃, relative humidity: 40%～60%.
Test method: get 20 of the examination Mus of fasting 16h, female, male half and half, the dosage that receives thing by 6244mg/kg.bw (irritating gastric capacity 0.2ml/10g.bw) is once irritated stomach give, observe 4d continuously, record poisoning manifestations and death condition.
Result of the test: do not see in the observation period that any poisoning symptom and death appear in the examination Mus, female, male white mice acute oral toxicity LD50 is all greater than 6244mg/kg.bw.It is no abnormal to dissect internal organs such as animal observation Mouse Liver, kidney, spleen, heart, lung.
Evaluation of result: according to acute oral toxicity grade scale in " cosmetics health standard " (Ministry of Public Health 1999), this Pericarpium Zanthoxyli hair nourishing liquid belongs to nontoxic level product through chmice acute per os toxicity test proof.
2, skin irritation test:
The experiment of transdermal stimulation property shows: Pericarpium Zanthoxyli hair nourishing liquid of the present invention is non-stimulated to skin.
(1) test material and method
Tried thing: the Pericarpium Zanthoxyli hair nourishing liquid;
Animal: 4 of regular grade Japan large ear rabbits, body weight 2.4-2.7 kilogram, the animal quality certification number: No. 2008064, Yunnan.Body is looked into the animal no abnormality seen.
Environmental condition: room temperature: 22 ℃-23 ℃, relative humidity: 66%-68%;
Test method: according to " cosmetics health standard " (version in 2007) acute skin irritation property test, tested preceding 24 hours, experimental animal back spinal column diamond wool is cut 3 centimetres of QUMAO scope 3 cm x.Get and directly spread upon on the skin of right side by the no originality of examination 0.5 gram, with clean gauze covering, with nonirritant immobilization with adhesive tape 2 hours.The negative contrast of an other side.Remove 1 hour, 24 hours, 48 hours 72 h observation animal subject contact site dermoreaction and records that tried behind the thing.
(2) result of the test
(3) conclusion:
Under this experimental condition, being tried thing Pericarpium Zanthoxyli hair nourishing liquid is nonirritant to the White Rabbit acute skin irritation test by the skin irritation strength grading.
3, human body experiment on probation:
The human body proof test of 200 people being done in hospital; The effective percentage of alopecia areata, alopecia totalis, seborrheic alopecia, post disease alopecia, simple property alopecia all reaches more than 98%; And can prevent and treat pathologic alopecia, seborrheic dermatitis and folliculitis, scalp itch effectively, have strong microcirculation, the activation scalp cells; Reduce the fat secretion, reduce the effect of scalp pomade.Have no side effect after putting on the skin and comfort is arranged being coated with on the scalp.
Four, the specific embodiment
Embodiment 1:
A kind of Pericarpium Zanthoxyli hair nourishing liquid is mainly by Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, and the raw extract of Fructus Cnidii and Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil are formed.Its percentage by weight is: Pericarpium Zanthoxyli accounts for 5.5% of total amount, and Cacumen Platycladi accounts for 6.6%, and Radix Angelicae Sinensis accounts for 3%; Rhizoma Zingiberis Recens accounts for 3%, and Fructus Cnidii accounts for 4.4%, and Borneolum Syntheticum accounts for 1%; Jojoba oil accounts for 3.8%, and rosemary ethereal oil accounts for 2%, and the Flos Matricariae chamomillae quintessence oil accounts for 2%; Solubilizing agent accounts for 8%, 65% ethanol and accounts for 12%, and surplus is a pure water.
Take by weighing Pericarpium Zanthoxyli 55g, Cacumen Platycladi 66g, Radix Angelicae Sinensis 30 grams, Rhizoma Zingiberis Recens 30 grams, Fructus Cnidii 44g, washing, oven dry.Mix, pulverize, cross 10 mesh sieves, join then in the crushing container, in container, add 65% ethanol of 10 times of above-mentioned raw materials weight again, under 60 ℃ of temperature conditions, stir and extracted 3 hours, filter, keep filtrating; 65% ethanol that in filtering residue, adds 6 times of pigment weight again carries out the second time by above-mentioned process conditions and extracts, and filters, and merges filtrating twice.By the method concentrating under reduced pressure of routine, get the about 50g of fluid extract, this is the A phase.
Get 10 gram Borneolum Syntheticums and 120 grams, 65% ethanol, under 40 ℃ of conditions, stir and make its abundant mixed dissolution, subsequent use, this is the B phase;
Get 38 gram Jojoba oils, 20 gram rosemary ethereal oils, 20 gram Flos Matricariae chamomillae quintessence oils and 80 gram solubilizing agents, stir at ambient temperature and make its abundant mixed dissolution, subsequent use, this is the C phase;
A, B, C three are added in the 662 gram water, stir, filter, promptly get the Pericarpium Zanthoxyli hair nourishing liquid.
Embodiment 2:
A kind of Pericarpium Zanthoxyli hair nourishing liquid is mainly by Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, and the raw extract of Fructus Cnidii and Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil are formed.Its percentage by weight is: Pericarpium Zanthoxyli accounts for 8% of total amount, and Cacumen Platycladi accounts for 8%, and Radix Angelicae Sinensis accounts for 5%, and Rhizoma Zingiberis Recens accounts for 3%; Fructus Cnidii accounts for 3%, and Borneolum Syntheticum accounts for 2%, and Jojoba oil accounts for 5%, and rosemary ethereal oil accounts for 3%; The Flos Matricariae chamomillae quintessence oil accounts for 3%, and solubilizing agent accounts for 10%, 65% ethanol and accounts for 15%, and surplus is a pure water.
Take by weighing Pericarpium Zanthoxyli 80g, Cacumen Platycladi 80g, Radix Angelicae Sinensis 50 grams, Rhizoma Zingiberis Recens 30 grams, Fructus Cnidii 30g, washing, oven dry.Mix, pulverize, cross 10 mesh sieves, join then in the crushing container, in container, add 65% ethanol of 10 times of above-mentioned raw materials weight again, under 60 ℃ of temperature conditions, stir and extracted 3 hours, filter, keep filtrating; 65% ethanol that in filtering residue, adds 6 times of pigment weight again carries out the second time by above-mentioned process conditions and extracts, and filters, and merges filtrating twice.By the method concentrating under reduced pressure of routine, get the about 62.1g of fluid extract, this is the A phase.
Get 20 gram Borneolum Syntheticums and 150 grams, 65% ethanol, under 40 ℃ of conditions, stir and make its abundant mixed dissolution, subsequent use, this is the B phase;
Get 50 gram Jojoba oils, 30 gram rosemary ethereal oils, 30 gram Flos Matricariae chamomillae quintessence oils and 100 gram solubilizing agents, stir at ambient temperature and make its abundant mixed dissolution, subsequent use, this is the C phase;
A, B, C three are added in the 557.9 gram water, stir, filter, promptly get the Pericarpium Zanthoxyli hair nourishing liquid.
Embodiment 3:
A kind of Pericarpium Zanthoxyli hair nourishing liquid is mainly by Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, and the raw extract of Fructus Cnidii and Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil are formed.Its percentage by weight is: Pericarpium Zanthoxyli accounts for 5% of total amount, and Cacumen Platycladi accounts for 5%, and Radix Angelicae Sinensis accounts for 6%, and Rhizoma Zingiberis Recens accounts for 6%; Fructus Cnidii accounts for 6%, and Borneolum Syntheticum accounts for 2%, and Jojoba oil accounts for 2%, and rosemary ethereal oil accounts for 1%; The Flos Matricariae chamomillae quintessence oil accounts for 1%, and solubilizing agent accounts for 5%, 65% ethanol and accounts for 10%, and surplus is a pure water.
Take by weighing Pericarpium Zanthoxyli 50g, Cacumen Platycladi 50g, Radix Angelicae Sinensis 60 grams, Rhizoma Zingiberis Recens 60 grams, Fructus Cnidii 60g, washing, oven dry.Mix, pulverize, cross 10 mesh sieves, join then in the crushing container, in container, add 65% ethanol of 10 times of above-mentioned raw materials weight again, under 60 ℃ of temperature conditions, stir and extracted 3 hours, filter, keep filtrating; 65% ethanol that in filtering residue, adds 6 times of pigment weight again carries out the second time by above-mentioned process conditions and extracts, and filters, and merges filtrating twice.By the method concentrating under reduced pressure of routine, get the about 64.4g of fluid extract, this is the A phase.
Get 20 gram Borneolum Syntheticums and 100 grams, 65% ethanol, under 40 ℃ of conditions, stir and make its abundant mixed dissolution, subsequent use, this is the B phase;
Get 20 gram Jojoba oils, 10 gram rosemary ethereal oils, 10 gram Flos Matricariae chamomillae quintessence oils and 50 gram solubilizing agents, stir at ambient temperature and make its abundant mixed dissolution, subsequent use, this is the C phase;
A, B, C three are added in the 725.6 gram water, stir, filter, promptly get the Pericarpium Zanthoxyli hair nourishing liquid.
Claims (2)
1. Pericarpium Zanthoxyli hair nourishing liquid; It is characterized in that: the primary raw material of hair nourishing liquid is: Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, Fructus Cnidii; Its percentage by weight is: Pericarpium Zanthoxyli accounts for 5%～8% of total amount, and Cacumen Platycladi accounts for 5%～8%, and Radix Angelicae Sinensis accounts for 3%～6%; Rhizoma Zingiberis Recens accounts for 3%～6%, and Fructus Cnidii accounts for 3%～6%.Above raw material is prepared into hair nourishing liquid with Borneolum Syntheticum, Jojoba oil, rosemary ethereal oil and Flos Matricariae chamomillae quintessence oil after mixed extraction, Borneolum Syntheticum accounts for 1%～2%; Jojoba oil accounts for 2%～5%; Rosemary ethereal oil accounts for 1%～3%, and the Flos Matricariae chamomillae quintessence oil accounts for 1%～3%, and solubilizing agent accounts for 5%～10%; 65% ethanol accounts for 10%～15%, and surplus is a pure water; Its preparation method is following:
(1) at first take by weighing Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens by above-mentioned hair nourishing liquid composition of raw materials, Fructus Cnidii, washing, oven dry mixes, and pulverizes, and joins in the extractor behind 10 mesh sieves excessively;
(2) 65% ethanol of 10 times of amounts of adding above-mentioned raw materials in extractor stirs under 60 ℃ ± 5 ℃ conditions and extracted 2～4 hours, filters; Keep filtrating, in filtering residue, add 65% ethanol of 6 times of material quantities then again, carry out the second time by above-mentioned process conditions and extract; Filter, merge filtrating twice;
The filtrating that (3) will obtain is carried out concentrating under reduced pressure, gets fluid extract;
(4) get the Borneolum Syntheticum and 65% ethanol of formula ratio, under 40 ℃ ± 5 ℃ conditions, stir and make its abundant mixed dissolution, subsequent use;
(5) get Jojoba oil, rosemary ethereal oil, Flos Matricariae chamomillae quintessence oil and the solubilizing agent of formula ratio, stir at ambient temperature and make its abundant mixed dissolution, subsequent use;
(6) (3), (4), (5) are added in the water of prescription surplus, stir, filter, promptly get the Pericarpium Zanthoxyli hair nourishing liquid.
2. the method for preparing of a Pericarpium Zanthoxyli hair nourishing liquid is characterized in that, specifically comprises the following steps:
(1) at first take by weighing Pericarpium Zanthoxyli, Cacumen Platycladi, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens by the hair nourishing liquid composition of raw materials of claim 1, Fructus Cnidii, washing, oven dry mixes, and pulverizes, and joins in the extractor after crossing 10 mesh sieves.
(2) 65% ethanol of 10 times of amounts of adding above-mentioned raw materials in extractor stirs under 60 ℃ ± 5 ℃ conditions and extracted 2～4 hours, filters; Keep filtrating, in filtering residue, add 65% ethanol of 6 times of material quantities then again, carry out the second time by above-mentioned process conditions and extract; Filter, merge filtrating twice;
The filtrating that (3) will obtain is carried out concentrating under reduced pressure, gets fluid extract;
(4) get the Borneolum Syntheticum and 65% ethanol of formula ratio, under 40 ℃ ± 5 ℃ conditions, stir and make its abundant mixed dissolution, subsequent use;
(5) get Jojoba oil, rosemary ethereal oil, Flos Matricariae chamomillae quintessence oil and the solubilizing agent of formula ratio, stir at ambient temperature and make its abundant mixed dissolution, subsequent use;
(6) (3), (4), (5) are added in the water of prescription surplus, stir, filter, promptly get the Pericarpium Zanthoxyli hair nourishing liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010127730XA CN101829035B (en) | 2010-03-19 | 2010-03-19 | Hair nourishing pepper liquid for pepper and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010127730XA CN101829035B (en) | 2010-03-19 | 2010-03-19 | Hair nourishing pepper liquid for pepper and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101829035A CN101829035A (en) | 2010-09-15 |
| CN101829035B true CN101829035B (en) | 2012-08-01 |
Family
ID=42713357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010127730XA Active CN101829035B (en) | 2010-03-19 | 2010-03-19 | Hair nourishing pepper liquid for pepper and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101829035B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188690B (en) * | 2011-04-27 | 2014-08-20 | 林秀生 | Hair growth lotion and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1035436A (en) * | 1988-12-28 | 1989-09-13 | 王玉花 | A kind of manufacture method of hair growth promoter |
| CN1579428A (en) * | 2003-08-01 | 2005-02-16 | 韩勇 | External ready-made preparation of traditional Chinese medicine to prevent lipsotrichia and promote hair growth |
| CN1843428A (en) * | 2005-04-07 | 2006-10-11 | 韩勇 | Chinese medicinal preparation for treating alopecia and promoting hair growth |
-
2010
- 2010-03-19 CN CN201010127730XA patent/CN101829035B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1035436A (en) * | 1988-12-28 | 1989-09-13 | 王玉花 | A kind of manufacture method of hair growth promoter |
| CN1579428A (en) * | 2003-08-01 | 2005-02-16 | 韩勇 | External ready-made preparation of traditional Chinese medicine to prevent lipsotrichia and promote hair growth |
| CN1843428A (en) * | 2005-04-07 | 2006-10-11 | 韩勇 | Chinese medicinal preparation for treating alopecia and promoting hair growth |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101829035A (en) | 2010-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Balch | Prescription for herbal healing | |
| CN105395467B (en) | A kind of Chinese medicine composition, skin beautifying cosmetic and its application | |
| CN105833187A (en) | Botanical medicine composition with acne removing effect and application | |
| CN104856909A (en) | Sleeping pack capable of reducing melanin sediments and preparation method thereof | |
| KR100873033B1 (en) | Cosmetic composition for massage pack | |
| Olisova et al. | Russian traditional medicine in dermatology | |
| CN106728340A (en) | Chinese medicine composition with hair care effect and its preparation method and application | |
| KR20070074076A (en) | Anti-atopic cosmetic composition | |
| CN109303724A (en) | A kind of novel maintenance stoste composition of releiving containing folium artemisiae argyi | |
| CN102133167B (en) | Freckle removing facial mask made of traditional Chinese medicine and preparation process thereof | |
| CN106039022A (en) | Skin brightening and whitening traditional Chinese medicinal composition, skin brightening and whitening traditional Chinese medicinal preparation, skin brightening and whitening mask and preparation method | |
| CN101829035B (en) | Hair nourishing pepper liquid for pepper and preparation method thereof | |
| CN101095889A (en) | Plaster for treating ache and method for preparing the same | |
| CN110179708A (en) | A kind of plant assigns essential oil living and preparation method | |
| CN104856920A (en) | Sleep facial mask capable of removing acne marks and preparation method of sleep facial mask | |
| JPH09208479A (en) | Salicaceae plant mixture | |
| CN100486636C (en) | Paste for treating dental hyperesthesia and its preparing method | |
| CN102743506A (en) | Camellia japonica oil acne lotion and preparation method thereof | |
| CN105963201A (en) | Medicinal and edible sugar reducing toothpaste and preparation method thereof | |
| CN105232437A (en) | Composition and shower gel for skin whitening and preparation method of composition | |
| CN102028723B (en) | Hair-restoring Chinese herbal medicament for treating and preventing alopecia and production method thereof | |
| CN101766697A (en) | Antifungal medicament for treating skin tinea and preparation method thereof | |
| WO2019142042A1 (en) | Synergistic medicinal preparation for treating skin disorders like tinea versicolor | |
| CN110302129A (en) | One kind educating hair anticreep scalp nursing solution | |
| CN109432244A (en) | A kind of Chinese medicine preparation and its preparation method and application improving sensitive skin state |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: YUNNAN XICAO RESOURCE DEVELOPMENT CO., LTD. Free format text: FORMER OWNER: YUNNAN ZICAI BIOLOG RESOURCES DEVELOPMENT CO., LTD. Effective date: 20130114 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20130114 Address after: 650106, No. two, Xinguang alley, 169 hi tech Industrial Development Zone, Yunnan, Kunming Patentee after: YUNNAN WEST GRASS RESOURCES DEVELOPMENT CO.,LTD. Address before: 650106, No. two, Xinguang alley, 169 hi tech Industrial Development Zone, Yunnan, Kunming Patentee before: Yunnan Zicai Biological Resources Development Co.,Ltd. |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A Sichuan pepper hair growth liquid and its preparation method Effective date of registration: 20231225 Granted publication date: 20120801 Pledgee: Hua Xia Bank Co.,Ltd. Kunming Branch Pledgor: YUNNAN WEST GRASS RESOURCES DEVELOPMENT CO.,LTD. Registration number: Y2023980073832 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |