CN101829027B - 多功能漱口水 - Google Patents
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- 239000002324 mouth wash Substances 0.000 title abstract description 6
- 229940051866 mouthwash Drugs 0.000 title abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000008367 deionised water Substances 0.000 claims abstract description 14
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 14
- 125000003118 aryl group Chemical group 0.000 claims abstract description 6
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 6
- 239000012459 cleaning agent Substances 0.000 claims abstract description 6
- 239000000645 desinfectant Substances 0.000 claims abstract description 6
- 239000003381 stabilizer Substances 0.000 claims abstract description 6
- 239000004075 cariostatic agent Substances 0.000 claims abstract description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 8
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 claims description 6
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 6
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims description 3
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 claims description 3
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 claims description 3
- 108010011485 Aspartame Proteins 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 3
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 3
- 239000000605 aspartame Substances 0.000 claims description 3
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 3
- 235000010357 aspartame Nutrition 0.000 claims description 3
- 229960003438 aspartame Drugs 0.000 claims description 3
- 235000003270 potassium fluoride Nutrition 0.000 claims description 3
- 239000011698 potassium fluoride Substances 0.000 claims description 3
- 229940085605 saccharin sodium Drugs 0.000 claims description 3
- 235000013024 sodium fluoride Nutrition 0.000 claims description 3
- 239000011775 sodium fluoride Substances 0.000 claims description 3
- 229960004711 sodium monofluorophosphate Drugs 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 229940013618 stevioside Drugs 0.000 claims description 3
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 3
- 235000019202 steviosides Nutrition 0.000 claims description 3
- 244000246386 Mentha pulegium Species 0.000 claims description 2
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- 210000004556 brain Anatomy 0.000 claims description 2
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- 239000000470 constituent Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 abstract description 9
- 241000894006 Bacteria Species 0.000 abstract description 5
- 206010006326 Breath odour Diseases 0.000 abstract description 4
- 208000032139 Halitosis Diseases 0.000 abstract description 4
- 208000002925 dental caries Diseases 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
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- 230000000675 anti-caries Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 2
- 235000019799 monosodium phosphate Nutrition 0.000 description 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 2
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 2
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Abstract
本发明公开了一种属于口腔保健配制品的制备技术领域的口腔护理液及其制备方法。该漱口水包含消毒剂、防龋齿剂、清洁剂、清香剂、甜味剂、稳定剂、去离子水。本发明所提供的漱口水能抑制、清除口腔细菌，有效地防止蛀牙，同时，消除口臭，保持口气清新。该漱口水还具有制备简单、稳定性好等优点。
Description
技术领域
本发明属于口腔保健配制品的制备技术领域，特别涉及一种同时具有清洁、消毒、防龋齿和清新口气作用的多功能漱口水。
背景技术
随着人们生活水平的提高，口腔卫生与健康越来越受到人们的重视，人们已经不再局限于早晚两次的刷牙，对于这样的人群，尤其是对于外出者，便于随身携带的漱口水已经成为一种生活必备和时尚。漱口水作为一种口腔保健用品，可以分为清洁型和治疗型两大类。清洁型漱口水主要作用是除去口腔异味，治疗型则主要对口腔常见病进行辅助治疗。虽然市场上已有一些品牌的漱口水，但能将这两方面结合起来，使之既能保护牙齿，又能清新口气的产品并不多。相关专利“漱口水及其制备方法”(中国专利CN1142939)和“高疗效漱口水”(中国专利CN1066585)所涉及的发明就属于治疗型的漱口水；“一种多功能纯天然漱口水及其制备方法”(中国专利CN101627965)虽然具有这两方面功效，但其有效成分涉及水不溶性成分蜂胶、厚朴，在配制存放时容易析出，导致漱口水的浑浊，影响其稳定性和质感。
因此，提供一种能同时具有清洁、消毒、防龋齿和清新口气作用，并且易于制作、方便携带、性能稳定的漱口水实为必要。
发明内容
本发明提供了一种同时具有清洁、消毒、防龋齿和清新口气作用的多功能漱口水。
本发明提供的漱口水包含消毒剂、清洁剂、清香剂、甜味剂、稳定剂、去离 子水。其具体组分与重量百分比如下：
1)0.1％-5％的消毒剂，优选0.5％-3％，消毒剂为过氧化氢；
2)0.5％-10％的清洁剂，优选1％-5％，清洁剂为吐温20、山梨醇、十二烷基磺酸钠中的一种或几种；
3)0.01％-1％的清香剂，优选0.1％-0.5％，清香剂为水溶性薄荷脑、薄荷精、水果味香精中的一种或几种；
4)0.01％-1％的甜味剂，优选0.05-0.5％，甜味剂为糖精钠、阿斯巴甜、三氯蔗糖、甜菊糖中的一种或几种；
5)0.05％-2％的稳定剂，优选0.1％-1％，稳定剂为焦磷酸钠、磷酸二氢钠、EDTA二钠中的一种或几种；
6)去离子水，余量为去离子水。
该漱口水还含有防龋齿剂，具体为氟化钠、氟化钾、单氟磷酸钠中的一种或几种，重量百分比为0.05％-5％，优选0.1％-2％。
漱口水制备方法：将所有组分加入去离子水中溶解。
与现在有技术相比，本发明所提供的漱口水能抑制、清除口腔细菌，有效地防止蛀牙，同时，消除口臭，保持口气清新。该漱口水还具有制备简单、稳定性好等优点。
具体实施方式
以下非限制性实施例进一步叙述本发明范围内的优选实施方案。在不背离本发明范围的情况下，本实施例的很多变化是可能的。
实施例1
组分 重量百分比(％)
过氧化氢 1.00
单氟磷酸钠 0.70
吐温20 1.50
柠檬香精 0.15
阿斯巴甜 0.10
焦磷酸钠 0.30
去离子水 96.25
制备方法：将所有组分加入去离子水中溶解。
实施例2
组分 重量百分比(％)
过氧化氢 0.5
氟化钠 1.9
山梨醇 3.0
薄荷脑 0.5
糖精钠 0.15
磷酸二氢钠 0.25
去离子水 93.7
制备方法：将所有组分加入去离子水中溶解。
实施例3
组分 重量百分比(％)
过氧化氢 2.0
氟化钾 0.8
十二烷基磺酸钠 1.0
柠檬香精 0.2
甜菊糖 0.10
EDTA二钠 0.4
去离子水 95.5
制备方法：将所有组分加入去离子水中溶解。
将48名试验者平均分成四组，对实施例1-3中的三种配方漱口水及市上现有漱口水进行测试。试验者每天早、中、晚餐后都使用指定漱口水，持续三天。每次餐后取口腔液检查漱口水对细菌清除率，并观察试验者使用后三小时内的口气清新情况。各实验组的细菌清除率都采用平均值计算，口气清新情况按有效率计算。
| 有害细菌清除率 | 口腔异味被完全掩盖的比例 | |
| 实施例1 | 83％ | 92％ |
| 实施例2 | 92％ | 100％ |
| 实施例3 | 92％ | 100％ |
| 对照组 | 26.4％ | 66.7％ |
Claims (1)
1.一种多功能漱口水，其特征在于，该漱口水包含消毒剂、清洁剂、清香剂、甜味剂、稳定剂、防龋齿剂和去离子水；
所述的消毒剂为过氧化氢，重量百分比为0.1％-5％；
所述的清洁剂为吐温20、山梨醇、十二烷基磺酸钠中的一种或几种，重量百分比为0.5％-10％；
所述的清香剂为水溶性薄荷脑、薄荷精、水果味香精中的一种或几种，重量百分比为0.01％-1％；
所述的甜味剂为糖精钠、阿斯巴甜、三氯蔗糖、甜菊糖中的一种或几种，重量百分比为0.01％-1％；
所述的稳定剂为EDTA二钠，重量百分比为0.05％-2％；
所述的防龋齿剂为氟化钠、氟化钾、单氟磷酸钠中的一种或几种，重量百分比为0.05％-5％；
所述的去离子水含量为除去其它组分含量，余量为去离子水。
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| CN2010101732348A CN101829027B (zh) | 2010-05-11 | 2010-05-11 | 多功能漱口水 |
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| CN2010101732348A CN101829027B (zh) | 2010-05-11 | 2010-05-11 | 多功能漱口水 |
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| CN101829027B true CN101829027B (zh) | 2012-07-04 |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263375B (zh) * | 2013-05-30 | 2015-09-09 | 云南七丹药业股份有限公司 | 一种含三七提取物的漱口水及其制备方法 |
| CN106109366A (zh) * | 2016-08-30 | 2016-11-16 | 南京巨鲨显示科技有限公司 | 一种漱口水及其制备方法 |
| CN110638672A (zh) * | 2019-09-16 | 2020-01-03 | 陈秋迎 | 口腔检查或治疗用漱口水 |
| CN112603837A (zh) * | 2020-12-31 | 2021-04-06 | 丽水学院 | 一种含漱液及使用方法 |
| CN113679624A (zh) * | 2021-08-11 | 2021-11-23 | 上海驻净电子科技有限公司 | 一种具有凉感的洁净口腔护理剂 |
| CN116474606B (zh) * | 2023-05-11 | 2023-11-28 | 金华政祺生物技术有限公司 | 电解中性离子漱口水的制备装置、工艺及方法 |
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| CN101455620A (zh) * | 2007-12-13 | 2009-06-17 | 王惠明 | 一种漱口片组合物及制备方法 |
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| BRPI0502145A (pt) * | 2005-06-03 | 2007-01-23 | Mauricio Duarte Da Conceicao | enxaguatório para prevenção e tratamento da halitose |
| US20070254260A1 (en) * | 2005-12-02 | 2007-11-01 | Alden Wayne S Iv | Oral care compositions, methods, devices and systems |
| DE102006053693A1 (de) * | 2006-11-13 | 2008-05-15 | Henkel Kgaa | Zweiphasiges Mundwasser |
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Effective date of registration: 20220518 Address after: 528200 third floor, building B, No. 19, Dongyuan Road, Yuechi village, he village, Lishui Town, Nanhai District, Foshan City, Guangdong Province (residence declaration) Patentee after: Guangdong Lishang Biotechnology Co.,Ltd. Address before: 276100 Baichang village, Lizhuang Town, Tancheng County, Linyi City, Shandong Province Patentee before: SHANDONG JIANRONG TEACHING EQUIPMENT CO.,LTD. |
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