CN101822761B - Umbilical treatment patch for relieving pain and promoting lactation after caesarean section operation - Google Patents
Umbilical treatment patch for relieving pain and promoting lactation after caesarean section operation Download PDFInfo
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- CN101822761B CN101822761B CN2009100147575A CN200910014757A CN101822761B CN 101822761 B CN101822761 B CN 101822761B CN 2009100147575 A CN2009100147575 A CN 2009100147575A CN 200910014757 A CN200910014757 A CN 200910014757A CN 101822761 B CN101822761 B CN 101822761B
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Abstract
The invention belongs to the medical technical field, and discloses an umbilical treatment patch for relieving pain and promoting lactation after caesarean section operation. The umbilical treatment patch is prepared by the following traditional Chinese medicines by weight parts: 20g of astragalus, 15g of codonopsis pilosula, 10g of rhizoma cyperi, 10g of rhizoma corydalis, 10g of myrrh, 10g of faeces trogopterori, 10g of herba Leonuri, 10g of atractylodes macrocephala, 10g of angelica, 10g of semen vaccariae and 6g of medulla tetrapanacis. The components are grinded into powder and sealed for reserve. When in use, Shenque acupoint is conventionally disinfected, vinegar is used to blending the drug powder into a paste cake and the paste cake is stuck on an umbilicus and fixed by external rubberized fabric; and the patch is changed once daily for three days. The umbilical treatment patch has the advantages of good analgesic effect, easy production, convenient use, no toxic and side effect and the like, thus promoting secretion of milk of a parturient woman, being favorable for peristalsis of gastrointestinal tract and promoting gas passage by anus.
Description
The invention belongs to Chinese medicine preparation, the umbilicus of pain relieving and promotion lactogenic is treated Chinese herbs paste behind the cesarean section that particularly a kind of pure Chinese medicine is made.
Puerpera behind the cesarean section can produce dysphoria because of incision pain makes the puerpera, and is nervous, and it is not good enough to sleep, stress such as position, limitation of activity, and then influence early stage galactopoiesis, have a strong impact on puerpera's quality of life and child's suckling.Traditional analgesia method is the intramuscular injection pethidine hydrochloride, and its analgesia time is short, weak effect.PECA can produce good analgesic effect, yet the analgesia also produces certain influence to galactopoiesis.
The purpose of this invention is to provide and a kind ofly can effectively alleviate puerpera's postoperative pain, can promote the umbilicus of galactopoiesis to treat Chinese herbs paste simultaneously.
The present invention is achieved in that
Pain relieving and promote the umbilicus of lactogenic to treat preparation behind the cesarean section is characterized in that it being the umbilical treatment patch that the Chinese medicine by following weight parts is made: Radix Astragali 20g, Radix Codonopsis 15g, Rhizoma Cyperi 10g, Rhizoma Corydalis 10g, Myrrha 10g, Oletum Trogopterori 10g, Herba Leonuri 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Angelicae Sinensis 10g, Semen Vaccariae 10g, Medulla Tetrapanacis 6g.Be ground into powder, seal standby.Routine disinfection SHENQUE acupoint during use, vinegar mediation go up medicated powder and become pasty state medicine cake, are affixed on umbilical opening, the external immobilization with adhesive tape.
After the present invention adopts above-mentioned prescription, have following clinical effectiveness:
1, can effectively alleviate postoperative pain, total effective rate reaches 94%; And can promote galactopoiesis, the colostrum time in puerperal obviously shifts to an earlier date.
2, help gastrointestinal motility, promote passage of gas by anus.
3, pure Chinese medicinal preparation has no side effect.
4, make simply, easy to use.
The present invention is made for pure Chinese medicine, and modern pharmacological research proves:
The Radix Astragali: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance.But with replenishing QI to invigorate the spleen, QI invigorating rises blood together with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis.Qi and blood deficiency after managing property.Short estrogen action is arranged, the endometrium growth is repaired.Can strengthen the phagocytic function of reticuloendothelial system, increase the ability of virus induction interferon, enhancing antibody is synthetic, and immune system is had dual regulation.The Anhydroalkannin analgesia, suppressing the NO generation is one of its analgesic mechanism.
Radix Codonopsis: invigorating the spleen and replenishing QI, promote the production of body fluid and nourish blood.Can shorten and clotting time, the quantity of platelet increasing and coagulation function, promotion tissue regeneration, reparation, promotion hemostasis in puerperal.
Rhizoma Corydalis: grasp the hot logical property of temperature of loosing, can invigorate blood circulation, again can circulation of qi promoting, have good pain relieving effect.Tetrahydropalmatine in the Rhizoma Corydalis is a raceme, and its great advantage as analgesic is that toxicity is little, safety big, no addiction.
Myrrha, Oletum Trogopterori, Herba Leonuri: promoting blood circulation and stopping pain, removing stasis to stop bleeding.Be mainly used in postpartum stagnation pain, be gynecological's multiparity key medicine.Can obviously improve the hemorheology situation, weaken chemical algogenic substance to the influence of sensory nerve ending and bring into play analgesic activity.Herba Leonuri acts on the puerperal uterus and is excitation, shows as uterus tension force and strengthens, and shrinkage amplitude increases, and the rhythm and pace of moving things is accelerated; Oletum Trogopterori has the effect of two-ways regulation blood, and the one side of existing promotion blood coagulation has the clot dissolution of promotion effect again, promptly have the hemostasis and the dual-use function of invigorating blood circulation, hemostasis and do not stay the stasis of blood, thus residue is got rid of as early as possible, uterus shortening repair time, the menstruation recovery time in advance.
Rhizoma Cyperi: soothing the liver row stagnates, QI and blood regulating.It is obvious that the Rhizoma Cyperi ethanol extract is separated heat effect, is characterized in rapid-action, longer duration, and stronger analgesic activity is arranged, and the Rhizoma Cyperi water extract is also seen stronger analgesic activity.
Semen Vaccariae: be good at promoting blood circulation, row and not living is walked and is not kept.Function promoting blood circulation to restore menstrual flow, stimulating milk secretion detumescence, the master contains compositions such as Semen Vaccariae glycosides, Gypsogenin, multiple monosaccharide, has pharmacological actions such as antiearly pregnancy, antitumor, excited uterus, promotion galactopoiesis.The effect that also has pain relieving, antiinflammatory.
Medulla Tetrapanacis: clearing away heat and promoting diuresis, ventilation stimulating milk secretion.Has diuresis preferably, antiinflammatory and refrigeration function.Polyoses content is abundant in the Medulla Tetrapanacis, and polysaccharide has certain adjusting immunity and antioxidation.
The Rhizoma Atractylodis Macrocephalae: air making-up and spleen enlivening has the effect of regulating immunologic function.
Radix Angelicae Sinensis: the promoting blood circulation and stopping pain of enriching blood.Radix Angelicae Sinensis for the uterus have excited with suppress two kinds of effects, its water solublity, non-volatile, the crystallinity composition can excited uterus and make it to shrink and strengthen, its volatile oil can suppress uterine smooth muscle and it is relaxed, and the Radix Angelicae Sinensis crude polysaccharides has analgesic effect.
Blood stasis due to qi deficiency is the principal element of puerperal disease, and the deficiency of vital energy is a basic factor, and blood stasis is a direct factor, is caused stopping in the blood stasis by the deficiency of vital energy.It is hemorrhage to be that deficiency of vital energy blood loses astringency inducing, and haemophilia stops forming the stasis of blood, the blood stasis internal memory, and the fresh blood uneasiness causes haemophilia again, and it is hemorrhage that gas is not had is appended, and gas is with hematochezia, and so vicious cycle is more than.Therefore, the puerperal disease blood stasis due to qi deficiency has dependency, and the QI invigorating blood stasis dispelling then is the base therapy principle of puerperal disease.Therefore, we select Radix Astragali tonifying Qi and lifting yang, and benefit is defended consolidating superficial resistance.Use replenishing QI to invigorate the spleen together with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, QI invigorating rises blood.Qi and blood deficiency after managing property.The Rhizoma Cyperi depressed liver-energy dispersing and QI regulating, Rhizoma Corydalis, Myrrha, Oletum Trogopterori, Herba Leonuri promoting blood circulation, removing blood stasis and relieving pain are played qi-supplementing, blood-engendering so altogether, the merit of regulating qi to disperse stagnation pain relieving.Radix Astragali anti-inflammatory analgesic in the present invention prescription, the Rhizoma Corydalis promoting the circulation of QI to relieve pain, Myrrha, Oletum Trogopterori, Herba Leonuri can obviously improve the hemorheology situation, weaken chemical algogenic substance analgesic activity is brought into play in the influence of sensory nerve ending.Rhizoma Cyperi also has strong analgesic activity.
Effectively pain relieving can be alleviated puerpera's intense strain, can promote galactopoiesis.Simultaneously, but the Semen Vaccariae promoting blood circulation to restore menstrual flow, the stimulating milk secretion detumescence has the effect that promotes galactopoiesis, and Medulla Tetrapanacis ventilation stimulating milk secretion has antiinflammatory, regulates immunity and antioxidation etc.Therefore, medicine of the present invention can promote galactopoiesis, has better curative effect.
For verifying therapeutic effect of the present invention, the present invention in January, 2008-2008 year December carried out following clinical trial in Shandong Province's Liaocheng City second the People's Hospital:
1. data and method
1.1 source of data and branch group selection in January, 2008～2008 year December all do not have serious obstetric complication, no breast developmental defect and endocrinopathy in descending caesarean delivered mature primipara's 200 examples of epidural anesthesia.Two groups of the complete five equilibriums at random of art: experimental group 100 examples, postoperative adopts medicine of the present invention; Matched group 100 examples, postoperative adopts PECA.Puerpera's postoperative is all carried out direct rooming-in and breast feeding, all uses disposable perineal pad to collect postoperative hemorrhage.
1.2 research method experimental group: use medicine of the present invention.Concrete grammar is to get Radix Astragali 20g, Radix Codonopsis 15g, Rhizoma Cyperi 10g, Rhizoma Corydalis 10g, Myrrha 10g, Oletum Trogopterori 10g, Herba Leonuri 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Angelicae Sinensis 10g, Semen Vaccariae 10g, Medulla Tetrapanacis 6g.Be ground into powder, seal standby.Cesarean section is finished the beginning medication, the routine disinfection SHENQUE acupoint, and the vinegar mediation is gone up medicated powder and is become pasty state medicine cake, is affixed on umbilical opening, and the external immobilization with adhesive tape is changed 1 every day, totally 3 days.Matched group: 10min used the analgesia of disposable micro analgesic pump postoperative epidural before operation finished.With medicine composition is that sieve is sent caine 150mg, fentanyl 0.5mg, dexamethasone 10mg, is diluted to 100ml with normal saline, continues flow 2.0ml/h.
1.3 observation index
1.3.1. analgesic effect: record postoperative 72h analgesic effect, the pain classification is divided into 4 grades by the WHO staging with postoperative pain: 0 grade is painless; The I level, mild pain can be stood, can orthobiosis, sleep is interference-free; The II level, the moderate constant pain, sleep is disturbed, and needs to use analgesic; The III level, strong constant pain, sleep is subjected to serious interference, need use analgesic.Pain degree 0-I level is that effectively the II-III level is invalid.
1.3.2 colostrum time, intestinal evacuation time and 24h postpartum hemorrhage amount.
1.4 statistical procedures: the relatively employing t check of measurement data, the relatively employing of enumeration data
The x2 check, there is statistical significance P＜0.05 for difference.
2. result
2.1 analgesic effect relatively, sees Table 1.
Table 1 liang group analgesic effect relatively
Two groups of analgesic effect effective percentage compare no difference of science of statistics (x2=0.096, P＞0.05).
2.2 the comparison of two groups of colostrum times, intestinal evacuation time and 24h postpartum hemorrhage amounts sees Table 2.
The comparison of table 2 liang group colostrum time, intestinal evacuation time and 24h postpartum hemorrhage amount
The experimental group colostrum time is shorter than matched group, and significant difference (t=6.84, P＜0.01) is arranged;
The intestinal evacuation time is shorter than matched group, and significant difference (t=3.99, P＜0.01) is arranged; The 24h postpartum hemorrhage amount is less than matched group, and significant difference (t=10.57, P＜0.01) is arranged.
Above-mentioned evidence: analgesic effect was good after the present invention was used for cesarean section, and is suitable with PCEA pump analgesic effect.Effectively puerpera's intense strain can be obviously alleviated in analgesia, and Semen Vaccariae, Medulla Tetrapanacis have the stimulating milk secretion effect among the present invention simultaneously, and the experimental group colostrum time is significantly shorter than matched group, and difference has statistical significance.Medicine of the present invention is a umbilical treatment patch, easy to use, patient need not carry on the back pipe, do not influence on patient's bed and activity down, Rhizoma Corydalis in the pharmaceutical formulation, but that medicine circulation of qi promoting such as Rhizoma Cyperi disappear is stagnant, can promote the recovery of patient's enterokinesia, experimental group intestinal evacuation time also is significantly shorter than matched group, and difference has statistical significance.Radix Astragali hemostasis by invigorating QI in the side, Radix Codonopsis can shorten and clotting time, and the quantity of platelet increasing and coagulation function promote tissue regeneration, reparation, promote the hemostasis in puerperal.But blood-activating stasis-removing kind Chinese medicine Myrrha, Oletum Trogopterori, Herba Leonuri blood circulation and promoting silt, the effect of two-ways regulation blood is arranged, the one side of existing promotion blood coagulation, the clot dissolution of promotion effect is arranged again, promptly have the hemostasis and the dual-use function of invigorating blood circulation, hemostasis and do not stay the stasis of blood, thus residue is got rid of as early as possible, uterus shortening repair time, the menstruation recovery time in advance.And Qi-tonifying drug and blood circulation promoting medicine be best compatibility, proves absolutely that the inrigorating qi and promoting blood circulation hemostasis is the therapeutic regimen of puerperal disease.
Below in conjunction with embodiment medicine of the present invention is elaborated.
Get Radix Astragali 20g, Radix Codonopsis 15g, Rhizoma Cyperi 10g, Rhizoma Corydalis 10g, Myrrha 10g, Oletum Trogopterori 10g, Herba Leonuri 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Angelicae Sinensis 10g, Semen Vaccariae 10g, Medulla Tetrapanacis 6g.Be ground into powder, seal standby.Cesarean section is finished the beginning medication, the routine disinfection SHENQUE acupoint, and the vinegar mediation is gone up medicated powder and is become pasty state medicine cake, is affixed on umbilical opening, and the external immobilization with adhesive tape is changed 1 every day, totally 3 days.Can effectively treat pain behind the cesarean section, promote the breast milk secretion.
Below for utilizing the concrete case of Drug therapy of the present invention:
Example 1. poplars * *, the woman, 25 years old, because of 39 weeks of menolipsis, lower abdomen weighed down the sense of expanding and was admitted to hospital in 1 day.Previously body is strong, the menstruation rule.Have a medical check-up: T36.7 ℃ of BP 150/100mmHg, the cardiopulmonary auscultation is normal, pot belly, the high 35cm in palace, abdominal circumference 106cm, head presentation, floating, fetal rhythm umbilicus lower-left, 140 times/minute, anodinia, fetal membrane are not broken.Auxiliary examination: B ultrasonic is pregnant evening, the tire of living, head position, amniotic fluid depth capacity 2.0cm.Tentative diagnosis: 39 all gestation, oligohydramnios.At the hard descending low-segment cesarean section of waist combined anesthesia, see in the art that amniotic fluid is clear, measure about 300ml, help childbirth one boy baby with LOA, the neonate outward appearance does not have deformity, Apgar scoring 1 minute 10 minutes, Placenta Hominis, fetal membrane are given birth to complete.Operation is smooth, and hemorrhage few, patient vital signs is steady in the art.Art finishes the routine disinfection SHENQUE acupoint, gives medicine of the present invention, and the vinegar mediation is gone up medicated powder and become pasty state medicine cake, is affixed on umbilical opening, the external immobilization with adhesive tape.Change totally 3 days every day 1 time.Patient does not have pain substantially, the back 6 hours beginning bed activitieses of performing the operation, and postoperative beginning in 10 hours out-of-bed activity, postoperative promptly had colostrum to secrete in 20 hours, and postoperative 24h amount of bleeding is about 203ml, the aerofluxus of postoperative patient 45h intestinal.Patient was in hospital 7 days, recovered good, took out stitches and left hospital.
Example 2. grandsons * *, the woman, 24 years old, because of menolipsis 43
+ 6Week is admitted to hospital.Previously body is strong, menstruation irregularis, 28-45 days menstrual period.Have a medical check-up: the auscultation of T37.1 ℃ of BP 100/60mmHg cardiopulmonary is normal, pot belly, and the high 32cm in palace, abdominal circumference 101cm, the fetal head presentation, the fetal rhythm umbilical part, 140 times/minute, anodinia, fetal membrane are not broken.B ultrasonic: evening is pregnant, the tire of living, head position, two weeks of cord around neck, amniotic fluid depth capacity 8.6cm.Tentative diagnosis: 43
+ 6All gestation, polyhydramnios, cord around neck.At the hard descending low-segment cesarean section of waist combined anesthesia, see in the art that amniotic fluid is clear, about 1250ml that exhausts is with the suitable childbirth in ROA position one boy baby, 2 weeks of cord round the neck, development nutrition can, outward appearance does not have deformity, Apgar scoring 1 minute 5 minutes is through inhaling expectorant, treatment such as oxygen uptake scoring in back 5 minutes 8 minutes.Please advise oxygen uptake to observe after the newborn department of pediatrics consultation of doctors.Afterbirth is given birth to complete, and intraoperative hemorrhage is few, and patient does not have discomfort.Art finishes the routine disinfection SHENQUE acupoint, gives medicine of the present invention, and the vinegar mediation is gone up medicated powder and become pasty state medicine cake, is affixed on umbilical opening, the external immobilization with adhesive tape.Change totally 3 days every day 1 time.Patient's mild pain can be stood, the back 8 hours beginning bed activitieses of performing the operation, and postoperative beginning in 14 hours out-of-bed activity, postoperative had colostrum to secrete in 30 hours, and postoperative 24h amount of bleeding is about 213ml, the aerofluxus of postoperative patient 41h intestinal.Patient was in hospital 7 days, recovered good, took out stitches and left hospital, and the baby leaves hospital after giving oxygen inhalation therapy.
Claims (1)
1. cesarean postoperative analgesia and promote the umbilical treatment patch of lactogenic, it is characterized in that: the Chinese medicine by following weight parts is made: Radix Astragali 20g, Radix Codonopsis 15g, Rhizoma Cyperi 10g, Rhizoma Corydalis 10g, Myrrha 10g, Oletum Trogopterori 10g, Herba Leonuri 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Angelicae Sinensis 10g, Semen Vaccariae 10g, Medulla Tetrapanacis 6g, above-mentioned Chinese medicine is ground into powder, the last medicated powder of vinegar mediation becomes pasty state medicine cake during use, is affixed on umbilical opening.
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| CN2009100147575A CN101822761B (en) | 2009-03-03 | 2009-03-03 | Umbilical treatment patch for relieving pain and promoting lactation after caesarean section operation |
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| CN105079396A (en) * | 2015-10-09 | 2015-11-25 | 张晓林 | Spray capable of relieving incision pain after caesarean section operation and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137904A (en) * | 1995-06-15 | 1996-12-18 | 郑洪斌 | Yikang Zhixue soluble granules |
| CN1785320A (en) * | 2005-10-08 | 2006-06-14 | 徐本荣 | Chinese medicine for treating postpartum continuous lochia, incomplete miscarriage, menstrual pain |
| CN101112519A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating postpartum tormina |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137904A (en) * | 1995-06-15 | 1996-12-18 | 郑洪斌 | Yikang Zhixue soluble granules |
| CN1785320A (en) * | 2005-10-08 | 2006-06-14 | 徐本荣 | Chinese medicine for treating postpartum continuous lochia, incomplete miscarriage, menstrual pain |
| CN101112519A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating postpartum tormina |
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